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About 177 results

ALLMedicine™ Juvenile Retinoschisis Center

Research & Reviews  87 results

Optical coherence tomography analyses based segmentation and relative intensity evaluat...
https://doi.org/10.1177/1120672121995110
European Journal of Ophthalmology; Christodoulou PD

Feb 17th, 2021 - We aim to provide a description of the optical coherence tomography findings in the outer macula hyperreflective bands of our patients with X-linked juvenile retinoschisis. Also to categorize these changes and to quantitatively and qualitatively c...

A case of undiagnosed X-linked retinoschisis presenting as unilateral macular demarcati...
https://doi.org/10.1177/1120672120943119
European Journal of Ophthalmology; Cozzupoli GM, Amoroso F et. al.

Jul 21st, 2020 - We intend to describe an uncommon presentation of X-linked juvenile retinoschisis (XLRS) in a 17-year-old boy showing a macular demarcation line in the right eye and an inferior peripheral bullous retinoschisis in both right and left eye, at his f...

Retinoschisin and Cardiac Glycoside Crosstalk at the Retinal Na/K-ATPase.
https://doi.org/10.1167/iovs.61.5.1
Investigative Ophthalmology & Visual Science; Schmid V, Plössl K et. al.

May 11th, 2020 - Mutations in the RS1 gene, which encodes retinoschisin, cause X-linked juvenile retinoschisis, a retinal dystrophy in males. Retinoschisin specifically interacts with the retinal sodium-potassium adenosine triphosphatase (Na/K-ATPase), a transmemb...

Clinical and Genetic Studies of X-Linked Juvenile Retinoschisis
https://clinicaltrials.gov/ct2/show/NCT00055029

Apr 28th, 2020 - Objectives: The overall goal of this protocol is to better understand the etiology of XLRS disease to facilitate further research to identify a potential treatment for the disease. The specific primary objectives of this study are to: Investigate ...

Retinal Function in X-Linked Juvenile Retinoschisis.
https://doi.org/10.1167/iovs.19-27897
Investigative Ophthalmology & Visual Science; Ambrosio L, Hansen RM et. al.

Nov 20th, 2019 - To assess retinal function in young patients with X-linked juvenile retinoschisis (XLRS), a disorder that is known to alter ERG postreceptor retinal components and also possibly photoreceptor components. ERG responses to full-field stimuli were re...

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Clinicaltrials.gov  89 results

Optical coherence tomography analyses based segmentation and relative intensity evaluat...
https://doi.org/10.1177/1120672121995110
European Journal of Ophthalmology; Christodoulou PD

Feb 17th, 2021 - We aim to provide a description of the optical coherence tomography findings in the outer macula hyperreflective bands of our patients with X-linked juvenile retinoschisis. Also to categorize these changes and to quantitatively and qualitatively c...

A case of undiagnosed X-linked retinoschisis presenting as unilateral macular demarcati...
https://doi.org/10.1177/1120672120943119
European Journal of Ophthalmology; Cozzupoli GM, Amoroso F et. al.

Jul 21st, 2020 - We intend to describe an uncommon presentation of X-linked juvenile retinoschisis (XLRS) in a 17-year-old boy showing a macular demarcation line in the right eye and an inferior peripheral bullous retinoschisis in both right and left eye, at his f...

Retinoschisin and Cardiac Glycoside Crosstalk at the Retinal Na/K-ATPase.
https://doi.org/10.1167/iovs.61.5.1
Investigative Ophthalmology & Visual Science; Schmid V, Plössl K et. al.

May 11th, 2020 - Mutations in the RS1 gene, which encodes retinoschisin, cause X-linked juvenile retinoschisis, a retinal dystrophy in males. Retinoschisin specifically interacts with the retinal sodium-potassium adenosine triphosphatase (Na/K-ATPase), a transmemb...

Clinical and Genetic Studies of X-Linked Juvenile Retinoschisis
https://clinicaltrials.gov/ct2/show/NCT00055029

Apr 28th, 2020 - Objectives: The overall goal of this protocol is to better understand the etiology of XLRS disease to facilitate further research to identify a potential treatment for the disease. The specific primary objectives of this study are to: Investigate ...

Retinal Function in X-Linked Juvenile Retinoschisis.
https://doi.org/10.1167/iovs.19-27897
Investigative Ophthalmology & Visual Science; Ambrosio L, Hansen RM et. al.

Nov 20th, 2019 - To assess retinal function in young patients with X-linked juvenile retinoschisis (XLRS), a disorder that is known to alter ERG postreceptor retinal components and also possibly photoreceptor components. ERG responses to full-field stimuli were re...

see more →

News  1 results

New FDA Orphan Drugs: AMT 011, Axitinib, Gene Therapy for Juvenile Retinoschisis
https://www.medscape.com/viewarticle/558018

Jun 8th, 2007 - June 8, 2007 — The US Food and Drug Administration (FDA) has granted orphan drug designation for AMT 011 for the treatment of lipoprotein lipase deficiency, axitinib for the treatment of pancreatic cancer, and adeno-associated viral vector express...

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