ALLMedicine™ Syndactyly Center

May 15th, 2022 - When a de novo balanced reciprocal translocation is identified in patients with multiple congenital abnormalities, attempts are often made to infer the relationship between the phenotype of the patient and genes in the proximity of the breakpoint....

May 14th, 2022 - The formation of the digits is a tightly regulated process. During embryogenesis, disturbance of genetic pathways in limb development could result in syndactyly; a common congenital malformation consisting of webbing in adjacent digits. Currently,...

May 4th, 2022 - This study aimed to analyze the reliability and validity of the Vancouver Scar Scale (VSS) and the Withey score after syndactyly release. Over a 3-year period, 13 patients who underwent syndactyly release were evaluated. The mean age at the time o...

Mar 31st, 2022 - Cutis marmorata telangiectatica congenita (CMTC) is characterized by coarse-meshed capillary malformations arranged in asymmetrically distributed patches. The disorder may be associated with hyper- or hypoplastic limbs, syndactyly, cleft palate, a...

Mar 12th, 2022 - Apert syndrome is a multisystem genetic disorder typically characterized by craniosynostosis and syndactyly. Studies also report an increased incidence of hearing loss in children with Apert syndrome in comparison to the general population. The ai...

Feb 2nd, 2021 - Takeaway First trimester use of macrolide antibiotics (mainly erythromycin, spiramycin, clarithromycin and azithromycin) was not associated with an increased risk of congenital heart defects (CHDs) as a whole. Erythromycin, clarithromycin and azit...

Sep 29th, 2020 - The Diagnosis: Onychodystrophy Secondary to Polydactyly Radiographs of the feet demonstrated an accessory distal phalanx of the left great toe with a similar smaller accessory distal phalanx on the right great toe (Figure). The patient was referre.

Apr 3rd, 2014 - Discussion This patient's presentation is consistent with Moebius (or Möbius) syndrome. Moebius syndrome is a rare congenital condition that was first described by German neurologist Paul Julius Möbius. The current definition varies among investig...

Aug 28th, 2013 - An examination of nearly 1 million birth records revealed a 3-fold increased risk for tetralogy of Fallot among infants whose mothers took fluconazole in the first trimester, according to a study published in the August 29 issue of the New England...

Jan 9th, 2006 - Action Points Remind patients, especially patients who are pregnant or are interesting in becoming pregnant, about this new danger of smoking. This study found a dose-response relationship between maternal smoking and an increased risk for webbed ...