×
About 2,273 results

ALLMedicine™ Osteogenesis Imperfecta Center

Research & Reviews  857 results

Experiences of Women of Short Stature During the Perinatal Period.
https://doi.org/10.1016/j.jogn.2022.03.006
Journal of Obstetric, Gynecologic, and Neonatal Nursing :... Nthenge S, Smith L et. al.

May 14th, 2022 - To explore the experiences of women of short stature, including women with dwarfism and osteogenesis imperfecta (OI), during the perinatal period. Qualitative descriptive. Telephone interviews with women of short stature from across the United Sta...

Genotype-phenotype relationship and follow-up analysis of a Chinese osteogenesis imperf...
https://doi.org/10.1016/j.eprac.2022.05.003
Endocrine Practice : Official Journal of the American Col... Wei S, Yao Y et. al.

May 14th, 2022 - Evaluating the genotype-phenotype relationship and the effect of treatment on the clinical course of Osteogenesis imperfecta (OI). We established a Chinese hospitalized OI cohort and followed up for an average of 6 years. All the patients were con...

Evaluation and Treatment of Patients With Connective Tissue Disease
https://clinicaltrials.gov/ct2/show/NCT00076830

May 13th, 2022 - This protocol seeks to formalize the application of accepted diagnostic and therapeutic measures in the study of individuals with known or suspected bone-related connective tissue disorders, including Osteogenesis Imperfecta and melorheostosis. It...

Osteoporosis in Solid Organ Transplantation Overview of Management
https://emedicine.medscape.com/article/128108-overview

May 2nd, 2022 - Practice Essentials Osteoporosis is common and the risk of fracture is high among patients who have undergone solid organ transplantation. [1] The pretransplant bone evaluation should include a careful history, with particular attention to risk fa...

Osteoporosis in Solid Organ Transplantation
https://emedicine.medscape.com/article/128108-print

May 2nd, 2022 - Osteoporosis is common and the risk of fracture is high among patients who have undergone solid organ transplantation.[1] The pretransplant bone evaluation should include a careful history, with particular attention to risk factors for osteoporosi...

see more →

Guidelines  1 results

Consensus guidelines on the use of bisphosphonate therapy in children and adolescents.
https://doi.org/10.1111/jpc.13768
Journal of Paediatrics and Child Health; Simm PJ, Biggin A et. al.

Mar 6th, 2018 - Bisphosphonate therapy is the mainstay of pharmacological intervention in young people with skeletal fragility. The evidence of its use in a variety of conditions remains limited despite over three decades of clinical experience. On behalf of the ...

see more →

Drugs  3 results see all →

Clinicaltrials.gov  27 results

Evaluation and Treatment of Patients With Connective Tissue Disease
https://clinicaltrials.gov/ct2/show/NCT00076830

May 13th, 2022 - This protocol seeks to formalize the application of accepted diagnostic and therapeutic measures in the study of individuals with known or suspected bone-related connective tissue disorders, including Osteogenesis Imperfecta and melorheostosis. It...

Genetics of Ehlers-Danlos Syndrome
https://clinicaltrials.gov/ct2/show/NCT03093493

Apr 28th, 2022 - Ehlers-Danlos Syndrome (EDS) is a genetic disease that affects collagen synthesis and structure resulting in multisystem connective tissue involvement with twelve different subtypes. The clinical manifestations of EDS include skin hyperextensibili...

Experimental Evaluation of Back Braces for the Treatment of Spinal Deformity Produced With 3D Printing Technology
https://clinicaltrials.gov/ct2/show/NCT04282408

Mar 31st, 2022 - The proposed investigation is a pilot study that involves pediatric patients affected by spinal deformity (Adolescent Idiopathic Scoliosis and Osteogenesis Imperfecta). The main goal is to evaluate the acceptability, the safety and the overall sat...

Clear Aligners for the Treatment of Dental Malocclusion in OI Types III and IV
https://clinicaltrials.gov/ct2/show/NCT04815564

Feb 28th, 2022 - Osteogenesis imperfecta (OI) is a heritable connective tissue disorder leading to frequent fractures and bone deformities. In about 90% of individuals with OI, the disease is caused by dominant mutations in one of the two genes coding for collagen...

Study to Assess the Efficacy and Safety of Setrusumab in Participants With Osteogenesis Imperfecta
https://clinicaltrials.gov/ct2/show/NCT05125809

Feb 24th, 2022 - Participants in Cohort A will be randomized 1:1:1 to receive setrusumab (low or high dose) or placebo. Participants will continue receiving their assigned dose of setrusumab until the phase 3 dose is determined. After the phase 3 dose(s) of setrus...

see more →

News  16 results

Anti-TGF-Beta Therapy Promising in Osteogenesis Imperfecta
https://www.medscape.com/viewarticle/969125

Feb 28th, 2022 - NEW YORK (Reuters Health) - In adults with osteogenesis imperfecta (OI), a single administration of fresolimumab, a pan-anti-TGF-beta neutralizing antibody, improved bone mass and turnover in a phase 1 study. Currently, there is no specific therap...

Gene, Stem-Cell Therapies Emerge as Options for Fetal Care
https://www.medscape.com/viewarticle/933799

Jul 14th, 2020 - NEW YORK (Reuters Health) - Fetal gene and stem-cell therapies are emerging as treatment options for select conditions, according to a new review. "Fetal cellular and gene therapies are feasible and primed to become viable treatments for a number ...

Product Update: Vistara; Ultravision trocar; CompuFlo Epidural; and Philips ultrasound
https://www.mdedge.com/node/159697/path_term/49726

Feb 28th, 2018 - PRENATAL SCREENING FOR SINGLE-GENE DISORDERS Vistara®, a non-invasive prenatal test (NIPT) from Natera, Inc, screens for single-gene disorders after 9 weeks’ gestation. Complementing the Panorama® NIPT, Vistara tests for major anatomic abnormaliti.

Osteogenesis Imperfecta Foundation Plans Conference
https://www.mdedge.com/clinicianreviews/article/158949/rare-diseases/osteogenesis-imperfecta-foundation-plans-conference

Feb 20th, 2018 - July 13-15, 2018, will be the dates of the biennial conference of the Osteogenesis Imperfecta Foundation. To take place in Baltimore, the program will feature forums with leading experts, practical living advice and research.

Osteogenesis Imperfecta Foundation Biennial Conference
https://www.mdedge.com/pediatrics/article/155756/rare-diseases/osteogenesis-imperfecta-foundation-biennial-conference

Jan 8th, 2018 - The Osteogenesis Imperfecta Foundation (OIF) will host its biennial national conference in Baltimore July 13-15, 2018. The program will feature sessions on medical advances and practical living guidance, along with forums with leading experts in o.

see more →

Patient Education  5 results see all →