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About 505 results

ALLMedicine™ AA Amyloidosis Center

Research & Reviews  186 results

DES-Amyloidoses "Amyloidoses through the looking-glass": A knowledgebase developed for ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312389
PloS One; Bajic VP, Salhi A et. al.

Jul 26th, 2022 - More than 30 types of amyloids are linked to close to 50 diseases in humans, the most prominent being Alzheimer's disease (AD). AD is brain-related local amyloidosis, while another amyloidosis, such as AA amyloidosis, tends to be more systemic. Th...

AA Amyloidosis associated with cancers.
https://doi.org/10.1093/ndt/gfac217
Nephrology, Dialysis, Transplantation : Official Publicat... Bharati J, Lahoud OB et. al.

Jul 23rd, 2022 - Systemic AA amyloidosis is associated with systemic inflammatory processes such as autoimmune disorders or chronic infections. In addition, AA amyloidosis can develop in a localized or systemic form in patients with malignant neoplastic disorders,...

Gain-of-function mutations in ALPK1 cause an NF-κB-mediated autoinflammatory disease: f...
https://doi.org/10.1136/annrheumdis-2022-222629
Annals of the Rheumatic Diseases; Kozycki CT, Kodati S et. al.

Jul 23rd, 2022 - To test the hypothesis that ROSAH (retinal dystrophy, optic nerve oedema, splenomegaly, anhidrosis and headache) syndrome, caused by dominant mutation in ALPK1, is an autoinflammatory disease. This cohort study systematically evaluated 27 patients...

Frequency of AA amyloidosis has decreased in Behçet's syndrome: a retrospective study w...
https://doi.org/10.1093/rheumatology/keac223
Rheumatology (Oxford, England); Karatemiz G, Esatoglu SN et. al.

Jun 4th, 2022 - A decline in the frequency of AA amyloidosis secondary to RA and infectious diseases has been reported. We aimed to determine the change in the frequency of AA amyloidosis in our Behçet's syndrome (BS) patients and to summarize the clinical charac...

Efficacy of canakinumab on AA amyloidosis in late-onset NLRP3-associated autoinflammato...
https://doi.org/10.1007/s10067-022-06130-1
Clinical Rheumatology; Itamiya T, Komai T et. al.

Mar 23rd, 2022 - There have been hundreds of reports on mutations in the NLRP3 gene related to NLRP3-associated autoinflammatory disease, but few of these mutations have occurred as both germline and somatic mosaic mutations. In this case-based review, we report a...

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Clinicaltrials.gov  8 results

Registre HEAR, Healthcare European Amyloidosis Registry
https://clinicaltrials.gov/ct2/show/NCT05101304

Nov 1st, 2021 - Amyloidosis is a rare disease characterized by infiltration and continuous accumulation of insoluble fibrillar proteins in the extracellular matrix in various organs including kidney, nerve, liver, heart and skeletal muscle. Its prevalence is esti...

Renal Manifestations of IBD
https://clinicaltrials.gov/ct2/show/NCT04301297

Jan 28th, 2021 - Inflammatory bowel diseases (IBD) comprise two types of chronic intestinal disorders: Crohn's disease (CD) and ulcerative colitis (UC). CD involves the ileum and colon, but it can affect any region of the intestine, often discontinuously. UC invol...

Establishment of Genomic, Transcriptomic and Functional Characteristics of Tumor Cells in Hyperinflammatory Hemopathies
https://clinicaltrials.gov/ct2/show/NCT04702932

Jan 11th, 2021 - Auto-inflammatory Diseases (AIDs) are defined by disorders of the innate immunity. They manifest themselves as episodes of inflammation associated with general signs and organ damage, mainly to the cutaneous, musculoskeletal and digestive systems....

Recurrent AA Amyloidosis After Renal Transplantation
https://clinicaltrials.gov/ct2/show/NCT02704065

Apr 18th, 2017 - AA amyloidosis is a rare but serious complication of several chronic inflammatory diseases including recurrent hereditary periodic fever syndromes. Although end-stage renal disease related to AA amyloidosis is well characterized, there is limited ...

Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis
https://clinicaltrials.gov/ct2/show/NCT01215747

Mar 10th, 2016 - The primary purpose of this study is to assess the efficacy and safety of treatment with Kiacta in adult patients with AA Amyloidosis.

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News  5 results

Fast Five Quiz: How Much Do You Know About Amyloidosis?
https://reference.medscape.com/viewarticle/903213_3

Nov 2nd, 2018 - Immunoglobulin light chain amyloidosis (AL) is the most common type of systemic amyloidosis in the United States, with an estimated 12,000 US adults currently living with the condition. Outside of the United States, AA amyloidosis is more common t...

Rely on Colchicine for FMF, Experts Say
https://www.medpagetoday.com/rheumatology/generalrheumatology/55872

Jan 27th, 2016 - Action Points An international group of experts has formulated new recommendations for the management of the autoinflammatory condition known as familial Mediterranean fever, focusing principally on the use of colchicine to prevent both acute atta...

Familial Mediterranean Fever
https://www.medscape.com/viewarticle/450325_1

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

Familial Mediterranean Fever
https://www.medscape.com/viewarticle/450325

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

AL Amyloidosis: Advances in Diagnostics and Treatment
https://www.medscape.com/viewarticle/918626

Abstract and Introduction Abstract AL amyloidosis (light chain; previously also called primary amyloidosis) is a systemic disease characterized by an amyloid deposition process affecting many organs, and which still has unsatisfactory survival of ...

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Patient Education  3 results see all →