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About 440 results

ALLMedicine™ Aa Amyloidosis Center

Research & Reviews  165 results

Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology...
https://doi.org/10.1038/s41467-021-27688-5
Nature Communications; Heerde T, Rennegarbe M et. al.

Jan 12th, 2022 - Several studies showed that seeding of solutions of monomeric fibril proteins with ex vivo amyloid fibrils accelerated the kinetics of fibril formation in vitro but did not necessarily replicate the seed structure. In this research we use cryo-ele...

A multicenter study of the clinical, laboratory characteristics, and potential prognost...
https://doi.org/10.1111/hdi.12993
Hemodialysis International. International Symposium on Ho... Bilgic Koylu E, Eren Sadioglu R et. al.

Jan 1st, 2022 - While light chain (AL) amyloidosis is more common in western countries, the most common type of amyloidosis is amyloid A (AA) amyloidosis in Eastern Mediterranean Region, including Turkey. Although worse prognosis has been attributed to the AL amy...

Dismal Prognosis of Acute Allergic Tubulointerstitial Nephritis in Patients with AA Amy...
https://doi.org/10.1159/000520151
Nephron Yildirim T, Gok-Oguz E et. al.

Dec 2nd, 2021 - Patients with AA amyloidosis may present with acute kidney injury that progresses to end-stage kidney disease in a short period of time. Acute allergic tubulointerstitial nephritis (aTIN) is a frequent cause of acute kidney injury in patients with...

Post-translational modification of amyloid a protein in patients with AA amyloidosis.
https://doi.org/10.1080/13506129.2021.1997985
Amyloid : the International Journal of Experimental and C... Kluve-Beckerman B, Smith JT et. al.

Nov 18th, 2021 - AA amyloidosis is a disease caused by extracellular deposition of insoluble β-pleated sheet fibrils composed of amyloid A (AA) protein, an amino (N)-terminal fragment of serum amyloid A (SAA). The deposits disrupt tissue structure and compromise o...

In the limelight: AA amyloidosis exposes TNF receptor-1 associated periodic syndrome.
https://doi.org/10.1093/rheumatology/keab540
Rheumatology (Oxford, England); Cavalli G, Campochiaro C et. al.

Sep 25th, 2021 - In the limelight: AA amyloidosis exposes TNF receptor-1 associated periodic syndrome.|2021|Cavalli G,Campochiaro C,Dagna L,|

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Clinicaltrials.gov  3 results

Recurrent AA Amyloidosis After Renal Transplantation
https://clinicaltrials.gov/ct2/show/NCT02704065

Apr 18th, 2017 - AA amyloidosis is a rare but serious complication of several chronic inflammatory diseases including recurrent hereditary periodic fever syndromes. Although end-stage renal disease related to AA amyloidosis is well characterized, there is limited ...

Progression of Renal Amyloidosis of FMF and Relation to Serum SAA Level
https://clinicaltrials.gov/ct2/show/NCT01168570

Aug 17th, 2010 - FMF is an inherited inflammatory disorder typically presented in most causes as recurrent episodes of fever and serositis. Phenotype II, another kind of this disorder, has atypical courses, when the inflammation proceeds without any clinical sign....

Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis
https://clinicaltrials.gov/ct2/show/NCT00035334

Feb 14th, 2006 - AA amyloidosis is associated with chronic inflammatory conditions (rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease), chronic infection (tuberculosis, osteomyelitis), and Familial Mediterranean Fever. Rheumatoid arthritis i...

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News  5 results

Fast Five Quiz: How Much Do You Know About Amyloidosis?
https://reference.medscape.com/viewarticle/903213_3

Nov 2nd, 2018 - Immunoglobulin light chain amyloidosis (AL) is the most common type of systemic amyloidosis in the United States, with an estimated 12,000 US adults currently living with the condition. Outside of the United States, AA amyloidosis is more common t...

Rely on Colchicine for FMF, Experts Say
https://www.medpagetoday.com/rheumatology/generalrheumatology/55872

Jan 27th, 2016 - Action Points An international group of experts has formulated new recommendations for the management of the autoinflammatory condition known as familial Mediterranean fever, focusing principally on the use of colchicine to prevent both acute atta...

Familial Mediterranean Fever
https://www.medscape.com/viewarticle/450325_1

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

Familial Mediterranean Fever
https://www.medscape.com/viewarticle/450325

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

AL Amyloidosis: Advances in Diagnostics and Treatment
https://www.medscape.com/viewarticle/918626

Abstract and Introduction Abstract AL amyloidosis (light chain; previously also called primary amyloidosis) is a systemic disease characterized by an amyloid deposition process affecting many organs, and which still has unsatisfactory survival of ...

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Patient Education  3 results see all →