ALLMedicine™ AA Amyloidosis Center

Feb 2nd, 2023 - History All patients with Schnitzler syndrome present with a chronic, recurrent, urticarial eruption. Pruritus is usually absent at the disease onset, but lesions may become mildly pruritic in approximately 45% of patients after 3-4 years. The ski...

Jan 17th, 2023 - Cardiac and neurological involvements are the main clinical features of hereditary transthyretin (ATTRv) amyloidosis. Few data are available about ATTRv amyloid nephropathy (ATTRvN). We retrospectively included 30 patients with biopsy-proven ATTRv...

Dec 23rd, 2022 - Long-term kidney transplantation (KT) results in patients with familial Mediterranean fever (FMF)-related amyloidosis are not well studied. This study reviewed the long-term survival outcomes of FMF patients who underwent KT. We compared the outco...

Dec 22nd, 2022 - Data on use of IL-1 blockers in kidney transplant recipients (KTRs) with familial Mediterranean fever (FMF) are very limited. We aimed to evaluate the efficacy and safety of anakinra and canakinumab in the transplantation setting. In this retrospe...

Dec 19th, 2022 - Practice Essentials Amyloidosis comprises a heterogeneous group of diseases in which normally soluble plasma proteins are deposited in the extracellular space in an abnormal, insoluble, fibrillar form. Amyloid A (AA) amyloidosis, previously known ...

Nov 1st, 2021 - Amyloidosis is a rare disease characterized by infiltration and continuous accumulation of insoluble fibrillar proteins in the extracellular matrix in various organs including kidney, nerve, liver, heart and skeletal muscle. Its prevalence is esti...

Jan 28th, 2021 - Inflammatory bowel diseases (IBD) comprise two types of chronic intestinal disorders: Crohn's disease (CD) and ulcerative colitis (UC). CD involves the ileum and colon, but it can affect any region of the intestine, often discontinuously. UC invol...

Jan 11th, 2021 - Auto-inflammatory Diseases (AIDs) are defined by disorders of the innate immunity. They manifest themselves as episodes of inflammation associated with general signs and organ damage, mainly to the cutaneous, musculoskeletal and digestive systems....

Apr 18th, 2017 - AA amyloidosis is a rare but serious complication of several chronic inflammatory diseases including recurrent hereditary periodic fever syndromes. Although end-stage renal disease related to AA amyloidosis is well characterized, there is limited ...

Mar 10th, 2016 - The primary purpose of this study is to assess the efficacy and safety of treatment with Kiacta in adult patients with AA Amyloidosis.

Nov 2nd, 2018 - Immunoglobulin light chain amyloidosis (AL) is the most common type of systemic amyloidosis in the United States, with an estimated 12,000 US adults currently living with the condition. Outside of the United States, AA amyloidosis is more common t...

Jan 27th, 2016 - Action Points An international group of experts has formulated new recommendations for the management of the autoinflammatory condition known as familial Mediterranean fever, focusing principally on the use of colchicine to prevent both acute atta...

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

Abstract and Introduction Abstract AL amyloidosis (light chain; previously also called primary amyloidosis) is a systemic disease characterized by an amyloid deposition process affecting many organs, and which still has unsatisfactory survival of ...