ALLMedicine™ Aa Amyloidosis Center

Jan 12th, 2022 - Several studies showed that seeding of solutions of monomeric fibril proteins with ex vivo amyloid fibrils accelerated the kinetics of fibril formation in vitro but did not necessarily replicate the seed structure. In this research we use cryo-ele...

Jan 1st, 2022 - While light chain (AL) amyloidosis is more common in western countries, the most common type of amyloidosis is amyloid A (AA) amyloidosis in Eastern Mediterranean Region, including Turkey. Although worse prognosis has been attributed to the AL amy...

Dec 2nd, 2021 - Patients with AA amyloidosis may present with acute kidney injury that progresses to end-stage kidney disease in a short period of time. Acute allergic tubulointerstitial nephritis (aTIN) is a frequent cause of acute kidney injury in patients with...

Nov 18th, 2021 - AA amyloidosis is a disease caused by extracellular deposition of insoluble β-pleated sheet fibrils composed of amyloid A (AA) protein, an amino (N)-terminal fragment of serum amyloid A (SAA). The deposits disrupt tissue structure and compromise o...

Sep 25th, 2021 - In the limelight: AA amyloidosis exposes TNF receptor-1 associated periodic syndrome.|2021|Cavalli G,Campochiaro C,Dagna L,|

Apr 18th, 2017 - AA amyloidosis is a rare but serious complication of several chronic inflammatory diseases including recurrent hereditary periodic fever syndromes. Although end-stage renal disease related to AA amyloidosis is well characterized, there is limited ...

Aug 17th, 2010 - FMF is an inherited inflammatory disorder typically presented in most causes as recurrent episodes of fever and serositis. Phenotype II, another kind of this disorder, has atypical courses, when the inflammation proceeds without any clinical sign....

Feb 14th, 2006 - AA amyloidosis is associated with chronic inflammatory conditions (rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease), chronic infection (tuberculosis, osteomyelitis), and Familial Mediterranean Fever. Rheumatoid arthritis i...

Nov 2nd, 2018 - Immunoglobulin light chain amyloidosis (AL) is the most common type of systemic amyloidosis in the United States, with an estimated 12,000 US adults currently living with the condition. Outside of the United States, AA amyloidosis is more common t...

Jan 27th, 2016 - Action Points An international group of experts has formulated new recommendations for the management of the autoinflammatory condition known as familial Mediterranean fever, focusing principally on the use of colchicine to prevent both acute atta...

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

Abstract and Introduction Background: The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinica...

Abstract and Introduction Abstract AL amyloidosis (light chain; previously also called primary amyloidosis) is a systemic disease characterized by an amyloid deposition process affecting many organs, and which still has unsatisfactory survival of ...