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About 4,830 results

ALLMedicine™ Antiphospholipid Syndrome Center

Research & Reviews  1,733 results

The challenges in diagnosing pediatric primary antiphospholipid syndrome.
https://doi.org/10.1177/09612033221108853
Lupus Demir S, Keskin A et. al.

Jun 25th, 2022 - Pediatric primary antiphospholipid syndrome (APS) is a very rare disease with significant distinctions from the APS in adults. Herein, we present our experience in the diagnosis and treatment of six pediatric primary APS patients, who met the upda...

Antiphospholipid Syndrome in Patients with Venous Thromboembolism.
https://doi.org/10.1055/s-0042-1749590
Seminars in Thrombosis and Hemostasis; Pengo V, Denas G

Jun 22nd, 2022 - Unprovoked (or provoked by mild risk factors) venous thromboembolism (VTE) in young patients, VTE in uncommon sites, or cases of unexplained VTE recurrence may be positive for antiphospholipid antibodies (aPL) and thus may be diagnosed with antiph...

Added value of antiphosphatidylserine/prothrombin antibodies in the workup of thromboti...
https://doi.org/10.1111/jth.15785
Journal of Thrombosis and Haemostasis : JTH; Vandevelde A, Chayoua W et. al.

Jun 18th, 2022 - Diagnosis of antiphospholipid syndrome (APS) requires persistent presence of lupus anticoagulant (LAC), anticardiolipin (aCL) IgG/IgM, or anti-β2 glycoprotein I (aβ2GPI) IgG/IgM antibodies. Other antiphospholipid antibodies (aPL) such as antiphosp...

Assessing the cardiovascular risk in patients with systemic lupus erythematosus: QRISK ...
https://doi.org/10.1016/j.ijcard.2022.06.040
International Journal of Cardiology; AliceMSc B, MassimoMD R et. al.

Jun 18th, 2022 - We aimed to apply and compare the QRISK3 and the adjusted Global AntiPhospholipid Syndrome (APS) Score (aGAPSS) in a cohort of systemic lupus erythematosus (SLE) patients, with and without a concomitant diagnosis of APS, in order to assess their a...

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Guidelines  4 results

First Latin American clinical practice guidelines for the treatment of systemic lupus e...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225798
Annals of the Rheumatic Diseases; Pons-Estel BA, Bonfa E et. al.

Jul 27th, 2018 - Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therap...

European evidence-based recommendations for diagnosis and treatment of paediatric antip...
https://doi.org/10.1136/annrheumdis-2016-211001
Annals of the Rheumatic Diseases; Groot N, de Graeff N et. al.

May 6th, 2017 - Antiphospholipid syndrome (APS) is rare in children, and evidence-based guidelines are sparse. Consequently, management is mostly based on observational studies and physician's experience, and treatment regimens differ widely. The Single Hub and A...

Practice Bulletin No. 132: Antiphospholipid syndrome.
https://doi.org/10.1097/01.AOG.0000423816.39542.0f
Obstetrics and Gynecology;

Nov 22nd, 2012 - Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of characteristic clinical features and specified levels of circulating antiphospholipid antibodies (Box 1 and Box 2). Diagnosis requires that at least one clinical ...

ACOG Practice Bulletin No. 118: antiphospholipid syndrome.
https://doi.org/10.1097/AOG.0b013e31820a61f9
Obstetrics and Gynecology;

Dec 22nd, 2010 - ACOG Practice Bulletin No. 118: antiphospholipid syndrome.|2010||

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Clinicaltrials.gov  82 results

Clinical Characteristics and Outcomes of SLE Patients Admitted to Critical Care Unit
https://clinicaltrials.gov/ct2/show/NCT05418855

Jun 14th, 2022 - Systemic lupus erythematosus (SLE) is a systemic heterogeneous autoimmune disease with a highly variable course and prognosis that many different organs may be affected . It has wide spectrum of clinical presentation that affects all ages and ethn...

Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia
https://clinicaltrials.gov/ct2/show/NCT05199909

May 27th, 2022 - Antiphospholipid syndrome (APS) is a disease spectrum characterized by thrombosis and/or pathological pregnancy, and characterized by persistent antiphospholipid antibodies (APL) positive in laboratory examination. The incidence of thrombocytopeni...

The BeLimumab Antiphospholipid Syndrome Trial (BLAST)
https://clinicaltrials.gov/ct2/show/NCT05020782

May 23rd, 2022 - AIM: The primary objective of the BeLimumab Antiphospholipid Syndrome Trial (BLAST) is to evaluate the safety and tolerability of belimumab for up to 24 months in patients with persistent aPL positivity and clinical features attributable to aPL th...

Placental Pathology and Inflammatory Factor Analysis of OAPS
https://clinicaltrials.gov/ct2/show/NCT05378516

May 18th, 2022 - 1. To clarify the correlation between antiphospholipid antibody, ACC1 expression level, Treg cell and placental pathological changes associated with antiphospholipid syndrome. 2. Reveal that antiphospholipid antibodies affect Treg cell differentia...

IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
https://clinicaltrials.gov/ct2/show/NCT03152058

May 2nd, 2022 - Antiphospholipid syndrome (APS) is an autoimmune disorder that occurs most commonly in women of reproductive-age and is associated with thrombosis and adverse pregnancy outcomes (APOs), such as fetal loss and preterm birth due to severe preeclamps...

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News  109 results

Infant with mottled skin
https://www.mdedge.com/familymedicine/article/255237/dermatology/infant-mottled-skin
MDedge Family Medicine;

Jun 9th, 2022 - The net-like, violaceous pattern on the infant’s skin was characteristic of livedo reticularis. Livedo reticularis is thought to arise from a change in underlying cutaneous blood flow.

EULAR CVD Management Guidance Focuses on Gout, Lupus, Vasculitis
https://www.medscape.com/viewarticle/969087

Feb 24th, 2022 - New recommendations from the European Alliance of Associations for Rheumatology (EULAR) provide both broad and detailed advice for cardiovascular risk management in various rheumatic and musculoskeletal diseases (RMDs), many of which can lead to a...

Scleral Plaques in Nephrogenic Systemic Fibrosis
https://www.mdedge.com/dermatology/article/251366/mixed-topics/scleral-plaques-nephrogenic-systemic-fibrosis
Sean Dreyer, MD, Lina Rodriguez, MD et. al.

Feb 2nd, 2022 - To the Editor: A 44-year-old man with a history of systemic lupus erythematosus (SLE) complicated by lupus nephritis, end-stage renal disease, and antiphospholipid syndrome was evaluated for progressive skin tightening over the last 3 years, predo.

Low Preconception Complement Levels Linked to Adverse Pregnancy Outcomes in Antiphospholipid Syndrome
https://www.medscape.com/viewarticle/960632

Oct 11th, 2021 - Low serum levels of two complement proteins are linked to worse pregnancy outcomes in women with antiphospholipid syndrome (APS), the results of a multicenter study appear to confirm. The study evaluated preconception complement levels in 260 preg...

Reticular Rash on the Chest
https://www.mdedge.com/dermatology/article/244078/reticular-rash-chest
Zaydi Javeed, MD, Noura Ayoubi, MD et. al.

Aug 10th, 2021 - The Diagnosis: Erythema Ab Igne Based on the clinical findings and history, a diagnosis of erythema ab igne (EAI), a skin reaction to chronic infrared radiation exposure, was made. The name of this condition translates from Latin as “redness from.

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Patient Education  4 results see all →