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About 1,245 results

ALLMedicine™ Paget Disease Center

Research & Reviews  443 results

Neutrophil-to-lymphocyte ratio is a potential prognostic biomarker for extramammary Pag...
https://doi.org/10.1111/1346-8138.16533
The Journal of Dermatology; Maeda T, Uehara J et. al.

Jul 30th, 2022 - The neutrophil-to-lymphocyte ratio (NLR) is a useful prognostic biomarker for many cancer types. However, the prognostic value of NLR in patients with extramammary Paget disease (EMPD) remains unclear. This study aimed to determine whether NLR is ...

A clinicopathologic study of malignancy in VCP-associated multisystem proteinopathy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287862
Orphanet Journal of Rare Diseases; Shmara A, Perez-Rosendahl M et. al.

Jul 16th, 2022 - Valosin containing protein (VCP) is an important protein with many vital functions mostly related to the ubiquitin-proteasome system that provides protein quality control. VCP-associated inclusion body myopathy with Paget disease of bone and front...

Autophagic factors in Paget disease.
https://doi.org/10.1016/j.prp.2022.154001
Pathology, Research and Practice; Karpathiou G, Mobarki M et. al.

Jul 8th, 2022 - Despite autophagy being a principal mechanism of tumor progression, its role has been never studied in Paget disease, a difficult to treat intraepithelial neoplasia affecting mainly the breast and the vulvar regions. Twenty seven cases (17 extrama...

The European Society of Gynaecological Oncology (ESGO), the International Society for t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232287
Journal of Lower Genital Tract Disease; Preti M, Joura E et. al.

Jun 29th, 2022 - The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD), and the European Federation for Colposcopy (EFC) develop...

The European Society of Gynaecological Oncology (ESGO), the International Society for t...
https://doi.org/10.1136/ijgc-2021-003262
International Journal of Gynecological Cancer : Official ... Preti M, Joura E et. al.

Jun 22nd, 2022 - The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD), and the European Federation for Colposcopy (EFC) develop...

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Clinicaltrials.gov  6 results

Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery
https://clinicaltrials.gov/ct2/show/NCT03770338

May 18th, 2022 - For this project, adult patients (>40 years) undergoing lumbar spinal fusion will be randomized to undergo teriparatide treatment for 1 month prior to surgery. Patients will have their baseline BMD assessed by DEXA scan must be considered as osteo...

Zoledronic Acid Compared to Percutaneous Treatment in Osteoid Osteoma
https://clinicaltrials.gov/ct2/show/NCT02739555

Feb 23rd, 2022 - Osteoid osteomas (OOs) are small, benign but painful bone tumors, mainly observed in children and young adults. Pain, almost universal, is characteristically greater at night. Pain is well relieved by NSAIDs but resolution is not always complete a...

Ultrasound Localization and Guided Injection for Superior Cluneal Nerve Entrapment
https://clinicaltrials.gov/ct2/show/NCT04478344

Dec 15th, 2021 - Introduction: Superior cluneal nerve (SCN) entrapment is the commonly omitted diagnosis in chronic low back pain. The superior cluneal nerve is the terminal branch of the lateral branches of the posterior rami of the L1-L3 spinal nerves, which pas...

Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
https://clinicaltrials.gov/ct2/show/NCT01353430

Apr 9th, 2021 - The investigators are researching families with inherited inclusion body myopathy (IBM) and/or Paget disease of bone (PDB) and/or dementia (FTD) which is also called IBMPFD. IBMPFD is caused by mutations in the VCP gene. Our main goal is to unders...

Characterization of Familial Myopathy and Paget Disease of Bone
https://clinicaltrials.gov/ct2/show/NCT01166854

Apr 5th, 2021 - Diffuse Optical Spectroscopy, the technique is fast and painless and was developed at the University of California, Irvine. The Diffuse Optical Spectroscopy instrument is actively involved in research studies, but is not yet a part of routine clin...

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News  48 results

Male presents with weakness in the legs and edema
https://www.mdedge.com/prostate-cancer-challenge-center/article/247409/prostate-cancer/male-presents-weakness-legs-and

Oct 14th, 2021 - Carcinomas like prostate cancer possess notable bony tropism and can metastasize to the lumbar‐sacral spine and pelvis, draining through the pelvic plexus of the lumbar region. Approximately 90% of patients with advanced prostate cancer develop bo.

Trending Clinical Topic: Hearing Loss
https://reference.medscape.com/viewarticle/953019

Jun 18th, 2021 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook. Find the late...

Trending Clinical Topic: Hearing Loss
https://www.medscape.com/viewarticle/953019

Jun 18th, 2021 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook. Find the late...

NCI-MATCH Results Offer Clues for the Use of Agents Across Tumor Types
https://www.onclive.com/view/nci-match-results-offer-clues-for-the-use-of-agents-across-tumor-types

Dec 5th, 2020 - Lyndsay Harris, MD A trickle of positive findings from NCI-MATCH, a precision medicine trial of numerous agents across tumor types, has encouraged investigators to broaden the number of trial arms, which now stand at 40, and expand enrollment. Si...

PD-1 Signaling in Extramammary Paget Disease
https://www.mdedge.com/dermatology/article/225511/mixed-topics/pd-1-signaling-extramammary-paget-disease/paget-disease
Mohammed Dany, MD, PhD

Jul 15th, 2020 - Primary extramammary Paget disease (EMPD) is an adnexal carcinoma of the apocrine gland ducts that presents as an erythematous patch on cutaneous sites rich with apocrine glands. 1 Primary EMPD can be in situ or invasive with the potential to becom.

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Patient Education  1 results see all →