About 37,620 results

ALLMedicine™ Systemic Lupus Erythematosus Center

Research & Reviews  12,269 results

Deciphering novel common gene signatures for rheumatoid arthritis and systemic lupus er...
PloS One; Tyagi N, Mehla K et. al.

Mar 18th, 2023 - Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) are the two highly prevalent debilitating and sometimes life-threatening systemic inflammatory autoimmune diseases. The etiology and pathogenesis of RA and SLE are interconnected in ...

Profiling of kidney involvement in systemic lupus erythematosus by deep learning using ...
Clinical and Experimental Nephrology; Kimura T, Ikeuchi H et. al.

Mar 18th, 2023 - Kidney involvement frequently occurs in systemic lupus erythematosus (SLE), and its clinical manifestations are complicated. We profiled kidney involvement in SLE patients using deep learning based on data from the National Database of Designated ...

Prevalence and clinical associations of ultrasound-confirmed enthesitis in systemic lup...
Rheumatology (Oxford, England); Fagni F, Bettiol A et. al.

Mar 18th, 2023 - To assess the prevalence of ultrasound (US)-confirmed enthesitis in a cohort of patients with systemic lupus erythematosus (SLE) and to analyze the clinical associations to enthesitis during the course of SLE. In a retrospective analysis of the SL...

The association between C509T, T869C, G915C gene polymorphisms of transforming growth f...
Medicine Chen N, Dai Y et. al.

Mar 18th, 2023 - The relationship between transforming growth factor-β1 (TGF- β1) gene polymorphisms and systemic lupus erythematosus (SLE) has been reported in many studies, but there were still controversies with regard to their conclusions. Relevant documents w...

Meta-analysis of clinical risk factors of patients with systemic lupus erythematosus co...
Medicine Meng Y, Chifeng L et. al.

Mar 18th, 2023 - To systematically evaluate the clinical risk factors of patients with systemic lupus erythematosus (SLE) complicated with invasive fungal infection (IFI) among patients. A meta-analysis was performed of all the literatures germane to estimate the ...

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Guidelines  11 results

The significance of the low sex ratios of offspring and of sibs of probands with system...
Early Human Development; James WH, Grech V

Sep 8th, 2019 - There is good evidence that there are significantly low sex ratios (proportions male) in the offspring of patients with some immune diseases e.g. systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). There is also strong evidence that ...

2019 update of the EULAR recommendations for the management of systemic lupus erythemat...
Annals of the Rheumatic Diseases; Fanouriakis A, Kostopoulou M et. al.

Mar 31st, 2019 - Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic literature review (01/2007-12/2017), followed by modified Delphi method, to f...

First Latin American clinical practice guidelines for the treatment of systemic lupus e...
Annals of the Rheumatic Diseases; Pons-Estel BA, Bonfa E et. al.

Jul 27th, 2018 - Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therap...

The British Society for Rheumatology guideline for the management of systemic lupus ery...
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: Executive Summary.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,immunology,therapy,

The British Society for Rheumatology guideline for the management of systemic lupus ery...
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,therapy,standards,standards,

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Drugs  605 results see all →

Clinicaltrials.gov  759 results

Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus

Mar 10th, 2023 - The primary objective is to evaluate the efficacy and safety of efavaleukin alfa in subjects with active systemic lupus erythematosus.

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

Mar 10th, 2023 - The purpose of this study is to evaluate long-term safety and tolerability of dapirolizumab pegol treatment.

Validation of Patient E-tool to Measure Systemic Lupus Activity

Mar 10th, 2023 - Systemic Lupus Erythematosus (SLE) is a rare and chronic autoimmune disease. Disease activity (DA) is marked by remissions, spontaneous relapses or induced by therapeutic modifications. SLE exposes to serious complications requiring close medical ...

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

Mar 10th, 2023 - The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population.

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE)

Mar 10th, 2023 - Study Description: This is a double blind placebo-controlled study to characterize whether blocking type I IFN receptor signaling with anifrolumab will lead to improvements in vascular function, decreases in vascular inflammation and modulation of...

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News  1,379 results

Painful blue fingers
MDedge Family Medicine; Arissa Young, MD, Marian Kaldas, MD et. al.

Mar 9th, 2023 - A 48-year-old woman with a history of systemic lupus erythematosus (SLE) presented to the emergency department from the rheumatology clinic for digital ischemia. The clinical manifestations of her SLE consisted predominantly of arthralgias, which.

Experts share real-world experience prescribing voclosporin, belimumab for lupus nephritis
Jeff Craven

Mar 8th, 2023 - Although patients with lupus nephritis recently gained two new add-on treatment options in voclosporin (Lupkynis) and belimumab (Benlysta), there have been little data published with real-world experience in using these drugs. Voclosporin, a calci.

New tool better estimates cardiovascular risk in people with lupus
Ted Bosworth

Feb 16th, 2023 - A tool that incorporates lupus-related variables with traditional risk factors provides a much more accurate assessment of cardiovascular (CV) risk in patients with systemic lupus erythematosus (SLE), according to data presented at the annual meet.

Pregnant women with RA and their infants at risk for adverse outcomes and rehospitalization

Feb 15th, 2023 - Key clinical point: Pregnant women with vs without rheumatoid arthritis (RA) and their infants should be closely monitored prenatally and during the year after delivery as they are at a higher risk for rehospitalization within 2 years and more lik.

Two biomarkers identify high-risk lupus nephritis
Ted Bosworth

Feb 14th, 2023 - At the time of a nephritis flare in patients with systemic lupus erythematosus (SLE), elevated levels of two neutrophil extracellular trap (NET) protein complexes, elastase-DNA and HMGB1-DNA, predict declining renal function, poor response to ther.

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Patient Education  25 results see all →