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About 29,098 results

ALLMedicine™ Systemic Lupus Erythematosus Center

Research & Reviews  10,076 results

Elevated serum cholesterol levels are associated with proteinuria over 0.5 g/day in pre...
https://doi.org/10.1177/03946320221101287
International Journal of Immunopathology and Pharmacology; Liu H, Li Q et. al.

May 21st, 2022 - Background: Systemic lupus erythematosus (SLE) commonly occurs in premenopausal women and is associated with elevated estrogen levels. Patients with SLE may have abnormal serum triglyceride (TG) levels, and lipid reportedly promotes kidney damage ...

Epigenetic Regulation of IFI44L Expression in Monocytes Affects the Functions of Monocy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113863
Journal of Immunology Research; Luo S, Wu R et. al.

May 21st, 2022 - Interferon-inducible 44 like (IFI44L) is a newly discovered interferon-induced gene and has been reported to overexpress in systemic lupus erythematosus (SLE). However, little is known about the mechanism and function of IFI44L overexpression in S...

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
https://clinicaltrials.gov/ct2/show/NCT04895696

May 20th, 2022 - The purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythematosus (SLE).

Study of Systemic Lupus Erythematosus
https://clinicaltrials.gov/ct2/show/NCT00001372

May 20th, 2022 - This research protocol will evaluate subjects with systemic lupus erythematosus (SLE) and their relatives to study the pathogenesis and natural history of the disease and the mechanisms leading to enhanced organ damage. Patients will be evaluated ...

Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus
https://clinicaltrials.gov/ct2/show/NCT04233164

May 20th, 2022 - Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome that causes pervasive immune dysregulation in all cells of the innate and adaptive immune system. Most patients with SLE require glucocorticoid treatment at some point of the dis...

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Guidelines  11 results

The significance of the low sex ratios of offspring and of sibs of probands with system...
https://doi.org/10.1016/j.earlhumdev.2019.104871
Early Human Development; James WH, Grech V

Sep 8th, 2019 - There is good evidence that there are significantly low sex ratios (proportions male) in the offspring of patients with some immune diseases e.g. systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). There is also strong evidence that ...

2019 update of the EULAR recommendations for the management of systemic lupus erythemat...
https://doi.org/10.1136/annrheumdis-2019-215089
Annals of the Rheumatic Diseases; Fanouriakis A, Kostopoulou M et. al.

Mar 31st, 2019 - Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic literature review (01/2007-12/2017), followed by modified Delphi method, to f...

First Latin American clinical practice guidelines for the treatment of systemic lupus e...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225798
Annals of the Rheumatic Diseases; Pons-Estel BA, Bonfa E et. al.

Jul 27th, 2018 - Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therap...

The British Society for Rheumatology guideline for the management of systemic lupus ery...
https://doi.org/10.1093/rheumatology/kex291
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: Executive Summary.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,immunology,therapy,

The British Society for Rheumatology guideline for the management of systemic lupus ery...
https://doi.org/10.1093/rheumatology/kex286
Rheumatology (Oxford, England); Gordon C, Amissah-Arthur MB et. al.

Oct 14th, 2017 - The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults.|2017|Gordon C,Amissah-Arthur MB,Gayed M,Brown S,Bruce IN,|diagnosis,therapy,standards,standards,

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Drugs  343 results see all →

Clinicaltrials.gov  249 results

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
https://clinicaltrials.gov/ct2/show/NCT04895696

May 20th, 2022 - The purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythematosus (SLE).

Study of Systemic Lupus Erythematosus
https://clinicaltrials.gov/ct2/show/NCT00001372

May 20th, 2022 - This research protocol will evaluate subjects with systemic lupus erythematosus (SLE) and their relatives to study the pathogenesis and natural history of the disease and the mechanisms leading to enhanced organ damage. Patients will be evaluated ...

Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus
https://clinicaltrials.gov/ct2/show/NCT04233164

May 20th, 2022 - Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome that causes pervasive immune dysregulation in all cells of the innate and adaptive immune system. Most patients with SLE require glucocorticoid treatment at some point of the dis...

Effect of Insoles in Patients With Systemic Lupus Erythematosus
https://clinicaltrials.gov/ct2/show/NCT04098055

May 19th, 2022 - Demonstrate that custom-made insoles improve painful symptomatology, health and foot function in subjects with SLE and podiatric involvement.

Hydroxychloroquine and Indapamide in SPMS
https://clinicaltrials.gov/ct2/show/NCT05013463

May 18th, 2022 - In patients with SPMS, there is ongoing slow and continuous loss of nerve cells, which causes damage to the brain and spinal cord. This ultimately becomes noticeable as slowly and continuously worsening disability. While the cause of this ongoing ...

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News  948 results

Expanded Treatment Options for Lupus Nephritis
https://www.mdedge.com/rheumatology/article/254271/lupus-connective-tissue-diseases/expanded-treatment-options-lupus
Joan Merrill, MD

May 6th, 2022 - Lupus nephritis (LN) affects approximately 25%-60% of patients with systemic lupus erythematosus. Currently, guideline-directed therapy recommends a combination of steroids plus either mycophenolate mofetil or cyclophosphamide.

Lupus May Lead to Worse Stroke Outcomes for Women, but Not Men
https://www.medscape.com/viewarticle/973212

Apr 29th, 2022 - Women with systemic lupus erythematosus (SLE) experience worse outcomes after an acute stroke than does the general population, but men with SLE do not, according to an analysis of the U.S. National Inpatient Sample presented at the annual meeting...

Experimental Lupus Therapy Only Shows Significant Effect at Highest Dose
https://www.medscape.com/viewarticle/970425

Mar 17th, 2022 - (Reuters Health) - Up to 54% of patients with systemic lupus erythematosus (SLE) were helped by daily therapy with Bristol Myers Squibb's experimental drug iberdomide, but only at the highest dose tested, researchers report in Thursday's New Engla...

Mixed Results for Oral Lupus Drug in Phase II
https://www.medpagetoday.com/rheumatology/lupus/97690

Mar 16th, 2022 - What could be the first oral medication specific for systemic lupus erythematosus (SLE) was more effective than placebo in a randomized phase II trial, though the results were something less than a home run. With 288 patients assigned to three dos...

Health Disparities Exist Across Rheumatology: What Can Be Done?
https://www.medscape.com/viewarticle/969350

Feb 28th, 2022 - Disparities in healthcare exist in every specialty. In rheumatology, health disparities look like lack of access to care and lack of education on the part of rheumatologists and their patients, according to a speaker at the 2022 Rheumatology Winte...

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Patient Education  12 results see all →