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About 1,590 results

ALLMedicine™ Neurotoxins Center

Research & Reviews  581 results

Cytochrome P450 enzymes and metabolism of drugs and neurotoxins within the mammalian br...
https://doi.org/10.1016/bs.apha.2022.04.003
Advances in Pharmacology (San Diego, Calif.); Stocco MR, Tyndale RF

Aug 12th, 2022 - Cytochrome P450 enzymes (CYPs) that metabolize xenobiotics are expressed and active in the brain. These CYPs contribute to the metabolism of many centrally acting compounds, including clinically used drugs, drugs of abuse, and neurotoxins. Althoug...

The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicoti...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352773
Nature Communications; Nys M, Zarkadas E et. al.

Aug 5th, 2022 - Bites by elapid snakes (e.g. cobras) can result in life-threatening paralysis caused by venom neurotoxins blocking neuromuscular nicotinic acetylcholine receptors. Here, we determine the cryo-EM structure of the muscle-type Torpedo receptor in com...

Microglia in multiple sclerosis: Protectors turn destroyers.
https://doi.org/10.1016/j.neuron.2022.06.023
Neuron Yong VW

Jul 27th, 2022 - Microglia are implicated in all stages of multiple sclerosis (MS). Microglia alterations are detected by positron emission tomography in people living with MS prior to the formation of structural lesions determined through magnetic resonance imagi...

Meet Argireline, the neurotoxinlike cosmeceutical
https://www.mdedge.com/dermatology/article/256393/aesthetic-dermatology/meet-argireline-neurotoxinlike-cosmeceutical
Chloe Goldman, MD

Jul 20th, 2022 - Acetyl hexapeptide-8 (or -3), better known by its brand name, Argireline (Lubrizol; Wickliffe, Ohio), is a synthetic peptide gaining popularity in cosmeceutical products for its antiaging benefits. Argireline was developed by the company Lipotec i.

Use of Cosmetic Facial Injectables After Facial Aesthetic Surgery.
https://doi.org/10.1093/asj/sjac171
Aesthetic Surgery Journal; Talwar AA, Shulkin JM et. al.

Jun 29th, 2022 - Over the last two decades, both invasive and minimally-invasive aesthetic procedures have proliferated. Aesthetic surgeons often recommend injectable treatments after cosmetic facial surgery for multiple reasons. Yet, literature is lacking on how ...

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Clinicaltrials.gov  17 results

Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhotic Patients
https://clinicaltrials.gov/ct2/show/NCT05279586

Mar 15th, 2022 - Hepatic encephalopathy (HE) is a reversible neuropsychiatric changes, it occurs in 30%-45% of cirrhotic patients during their life. Once HE is developed, the 1-year mortality exceeds 60%. The high morbidity and mortality combined with the costs un...

Effect of Training on Brain Volume in Ataxia
https://clinicaltrials.gov/ct2/show/NCT04837027

Jan 11th, 2022 - Individuals with degenerative cerebellar disease (DCD) exhibit gradual loss of coordination resulting in impaired balance, gait deviations, and severe, progressive disability. With no available disease-modifying medications, balance training is th...

Ataxia and Exercise Disease Using MRI and Gait Analysis
https://clinicaltrials.gov/ct2/show/NCT03701776

Nov 4th, 2021 - Individuals with degenerative cerebellar disease (DCD) exhibit gradual loss of coordination resulting in impaired balance, gait deviations, and severe, progressive disability. With no available disease-modifying medications, balance training is th...

Environmental Epidemiology of Essential Tremor
https://clinicaltrials.gov/ct2/show/NCT04576676

Sep 28th, 2021 - This research is devoted to studying the causes of tremor, and especially essential tremor (ET), which is the most common type of tremor. Since 2000, this lab has been investigating whether several environmental neurotoxins are associated with ET....

Evaluation of the Effect of Cooled Haemodialysis on Cognitive Function in Patients Suffering With End-stage KD
https://clinicaltrials.gov/ct2/show/NCT03645733

Feb 11th, 2020 - Patients with End-Stage Kidney Disease (ESKD) need haemodialysis to remove excess toxins and fluid from the body and maintain life. They also must restrict their fluid intake, take a median of 19 medications and follow a special diet1. In the UK, ...

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News  37 results

Meet Argireline, the neurotoxinlike cosmeceutical
https://www.mdedge.com/dermatology/article/256393/aesthetic-dermatology/meet-argireline-neurotoxinlike-cosmeceutical
Chloe Goldman, MD

Jul 20th, 2022 - Acetyl hexapeptide-8 (or -3), better known by its brand name, Argireline (Lubrizol; Wickliffe, Ohio), is a synthetic peptide gaining popularity in cosmeceutical products for its antiaging benefits. Argireline was developed by the company Lipotec i.

New Botulism Guidelines Focus on Mass-Casualty Events
https://www.medscape.com/viewarticle/952251

Jun 1st, 2021 - Botulinum toxin is said to be the most lethal substance known. Inhaling just 1-3 nanograms of toxin per kilogram of body mass constitutes a lethal dose.  Now the Centers for Disease Control and Prevention (CDC) has published the first comprehensiv...

Does Eating Fish Protect the Brain Against Air Pollution's Harmful Effects?
https://www.staging.medscape.com/viewarticle/934117

Jul 17th, 2020 - Moderate dietary intake of omega-3 polyunsaturated fatty acids in the form of one to two servings of fish weekly may help counteract the potential harmful effects of air pollution on the brain, a new study suggests. Among older women living in are...

Does Eating Fish Protect the Brain Against Air Pollution's Harmful Effects?
https://www.medscape.com/viewarticle/934117

Jul 17th, 2020 - Moderate dietary intake of omega-3 polyunsaturated fatty acids in the form of one to two servings of fish weekly may help counteract the potential harmful effects of air pollution on the brain, a new study suggests. Among older women living in are...

What’s Eating You? Dusky Pigmy Rattlesnake Envenomation and Management
https://www.mdedge.com/dermatology/article/211554/practice-management/whats-eating-you-dusky-pigmy-rattlesnake-envenomation
Mario J. Sequeira, MD, Andrew J. Sequeira

Nov 5th, 2019 - Rattlesnakes are pit vipers with a rattle attached to the tip of the tail and facial pits located between the eyes and nose with a special organ that detects heat energy (infrared light) and is used for hunting prey. There are 2 genera of rattlesn.

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Patient Education  1 results see all →