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About 1,185 results

ALLMedicine™ Lung Pathology Center

Research & Reviews  455 results

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.
https://doi.org/10.1371/journal.ppat.1010498
PLoS Pathogens; Belouzard S, Machelart A et. al.

May 20th, 2022 - Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those exhibiting antiviral activity agai...

Using Biomarkers to Predict TB Treatment Duration
https://clinicaltrials.gov/ct2/show/NCT02821832

May 13th, 2022 - Shortening the duration of treatment for patients with drug sensitive tuberculosis from 6 to 4 months has been attempted many times in clinical trials but thus far all have failed. These failures reveal our incomplete understanding of factors driv...

Role of Genetic Factors in the Development of Lung Disease
https://clinicaltrials.gov/ct2/show/NCT00001532

May 13th, 2022 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation.
https://doi.org/10.1016/j.taap.2022.116044
Toxicology and Applied Pharmacology; Ulu A, Sveiven S et. al.

May 8th, 2022 - IL-22 is a unique cytokine that is upregulated in many chronic inflammatory diseases, including asthma, and modulates tissue responses during inflammation. However, the role of IL-22 in the resolution of inflammation and how this contributes to lu...

Verdiperstat attenuates acute lung injury by modulating MPO/μ-calpain/β-catenin signaling.
https://doi.org/10.1016/j.ejphar.2022.174940
European Journal of Pharmacology; Ren R, Xu Z et. al.

Apr 25th, 2022 - Verdiperstat, a myeloperoxidase (MPO) inhibitor, is a well-known drug used for the treatment of multisystem atrophy. However, its therapeutic effect on acute lung injury (ALI) remains to be elucidated. In this study, the effect of verdiperstat on ...

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Guidelines  1 results

Pneumothorax and Pregnancy: A Systematic Review of the Current Literature and Proposal ...
https://doi.org/10.1055/s-0040-1702160
The Thoracic and Cardiovascular Surgeon; Agrafiotis AC, Assouad J et. al.

Mar 22nd, 2020 - Spontaneous pneumothorax occurs rarely during pregnancy with less than 100 cases reported in the English literature. There is no strong evidence concerning the treatment of spontaneous pneumothorax during pregnancy and labor. The aim of this study...

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Clinicaltrials.gov  10 results

Using Biomarkers to Predict TB Treatment Duration
https://clinicaltrials.gov/ct2/show/NCT02821832

May 13th, 2022 - Shortening the duration of treatment for patients with drug sensitive tuberculosis from 6 to 4 months has been attempted many times in clinical trials but thus far all have failed. These failures reveal our incomplete understanding of factors driv...

Role of Genetic Factors in the Development of Lung Disease
https://clinicaltrials.gov/ct2/show/NCT00001532

May 13th, 2022 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

HIV-related Accelerated Aging of the Airway Epithelium
https://clinicaltrials.gov/ct2/show/NCT01974219

Jun 18th, 2021 - While the epidemiologic data linking HIV infection to an increased risk for COPD is clear, the pathogenesis of the accelerated development of COPD in HIV infected smokers is not understood. We have focused on the SAE as the central target for the ...

#StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19
https://clinicaltrials.gov/ct2/show/NCT04385264

May 11th, 2021 - BACKGROUND Despite drastic quarantine measures, COVID-19 continues to propagate and threatens global healthcare systems by saturating their capacity with high transmissibility and the particularly protracted length of stay needed by those requirin...

The Added Value of CT Scanning in Patients With an Unilateral Pleural Effusion
https://clinicaltrials.gov/ct2/show/NCT03270215

Dec 17th, 2020 - Objectives Is CT-scanning better than chest x-ray plus a thoracocentesis for discriminating malignant from benign pleural effusions? What is the added value of a CT-scanning to chest x-ray plus thoracocentesis for discriminating malignant from ben...

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News  8 results

Trastuzumab Deruxtecan Shows “Remarkable” Responses in HER2+ Breast Cancer, Requires Monitoring of Respiratory Symptoms
https://www.onclive.com/view/trastuzumab-deruxtecan-shows-remarkable-responses-in-her2-breast-cancer-requires-monitoring-of

Jul 16th, 2020 - Fam-trastuzumab deruxtecan-nxki (Enhertu) has shown impressive response rates and progression-free survival (PFS) outcomes in patients with heavily pretreated metastatic HER2-positive breast cancer, explained Charles E. Geyer, Jr, MD, who added th...

'Chemical Burns' Seen as Possible Cause of Vaping Lung Damage
https://www.staging.medscape.com/viewarticle/919361

Oct 3rd, 2019 - Lung injuries from vaping probably result from direct toxicity or tissue damage caused by noxious chemical fumes, rather than from an accumulation of lipids in the lungs, pathology data suggest. "We were not surprised by what we found, regarding t...

'Chemical Burns' Seen as Possible Cause of Vaping Lung Damage
https://www.medscape.com/viewarticle/919361

Oct 3rd, 2019 - Lung injuries from vaping probably result from direct toxicity or tissue damage caused by noxious chemical fumes, rather than from an accumulation of lipids in the lungs, pathology data suggest. "We were not surprised by what we found, regarding t...

CDC: Black Lung Resurgent Among Kentucky Coal Miners
https://www.medpagetoday.com/pulmonology/generalpulmonary/62111

Dec 16th, 2016 - The U.S. Centers for Disease Control and Prevention is reporting a large, recent cluster of advanced black lung disease occurring among coal miners living and working in a single region of eastern Kentucky. Between January 2015 and August 2016, 60...

Supraglottic Airway Versus Endotracheal Tube During Interventional Pulmonary Procedures
https://www.medscape.com/viewarticle/922110

Abstract and Introduction Abstract Background: As the field of interventional pulmonology (IP) expands, anesthesia services are increasingly being utilized when complex procedures of longer duration are performed on sicker patients with high risk ...

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