ALLMedicine™ Crossmatching Center

May 6th, 2022 - HLA Ab analysis is carried out as a routine assay both pre- and post-heart transplantation to identify Abs directed against HLA with a focus post-transplant on those Abs that are donor-specific. While virtual crossmatching has decreased the requir...

Apr 3rd, 2022 - Transfusion of ABO blood group-mismatched blood or administration to the wrong recipient may result in fatal adverse events. To prevent these types of errors, various strategies have been employed. Recently, we developed a novel sample collection ...

Feb 24th, 2022 - Comprehensive and accurate human leukocyte antigen (HLA) typing within a short turnaround time is a crucial initial step for allocating deceased donor organs for transplantation. Erroneous HLA typing of deceased donors can be catastrophic and resu...

Feb 21st, 2022 - Complement dependent cytotoxicity crossmatch (CDC-XM) has been the original standard crossmatch test, whereas, flow cytometry crossmatch (FCXM) is an enhanced and highly sensitive crossmatch assay performed to detect donor specific anti-HLA antibo...

Sep 24th, 2021 - All UK H&I laboratories and transplant units operate under a single national kidney offering policy, but there have been variations in approach regarding when to undertake the pre-transplant crossmatch test. In order to minimize cold ischaemia tim...

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

Jul 31st, 2010 - Ongoing technological developments in antibody detection and characterisation allowing relative quantitation of HLA-specific antibody levels, combined with crossmatch results, now allow a graded assessment of patient potential donor immunological ...

Sep 17th, 2009 - Approximately 20 percent of corneal transplant patients, about 6,000 per year, face donor tissue rejection at rates of up to 60 percent because of corneal vascularization or prior graft rejection. Histocompatibility antigen matching and/or crossma...

Jun 30th, 2018 - David R. Gandara, MD Each morning, David R. Gandara, MD, wakes up energized to spend another day as an oncologist in lung cancer practice and research, a field in which advances have been more rapid than anything previously seen in oncology. As th...

PALM DESERT, CALIF. — Just 9% of obstetric patients who required transfusions had no identifiable risk factors for hemorrhage in a study presented at the annual meeting of the Society for Obstetric Anesthesia and Perinatology.