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About 255 results

ALLMedicine™ Crossmatching Center

Research & Reviews  81 results

COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted ren...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946887
Human Immunology; Roll GR, Bray RA et. al.

Mar 4th, 2023 - Although rare, infection and vaccination can result in antibodies to human leukocyte antigens (HLA). We analyzed the effect of SARS-CoV-2 infection or vaccination on HLA antibodies in waitlisted renal transplant candidates. Specificities were coll...

Porcine Kidney Xenotransplantation in Patients With End-Stage Kidney Disease
https://clinicaltrials.gov/ct2/show/NCT05340426

Feb 16th, 2023 - Twenty patients with ESKD listed for kidney allotransplantation at UAB will be enrolled to receive either one or two porcine kidney xenotransplants from a 10-GE pig donor, contingent on the pig's overall size at the time of procurement. Recruitmen...

Comparison of platelet antibody screen, crossmatching and HLA antibody testing in patie...
https://doi.org/10.1016/j.transci.2022.103622
Transfusion and Apheresis Science : Official Journal of T... Chapman JM, Wendt L et. al.

Dec 20th, 2022 - Patients undergoing recurrent platelet transfusions can become refractory to these transfusions. Platelet antibody screens (Immucor), platelet crossmatching assays (Immucor), and HLA antibody testing are commonly used to test these patients. The r...

Alloimmunization following antigen-negative red blood cell transfusion.
https://doi.org/10.1111/trf.17208
Transfusion Jacobs JW, Binns TC et. al.

Dec 3rd, 2022 - Red blood cell (RBC) alloimmunization can occur secondary to transfusion or pregnancy. It is observed most frequently among patients with hemoglobinopathies and myeloid neoplasms. Although previous antigen exposure is generally required for alloim...

Combined Liver-Kidney Transplantation in High Immunologic Risk Recipients: Kidney Graft...
https://doi.org/10.1016/j.transproceed.2022.10.007
Transplantation Proceedings; Cholbi E, Espí J et. al.

Nov 20th, 2022 - Candidates for combined liver-kidney transplant frequently present pretransplant HLA sensitization in most cases related to elevated prior transfusion requirements. The urgency criterion and the evidence of the protective effect at the immunologic...

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Guidelines  2 results

Red blood cell specifications for patients with hemoglobinopathies: a systematic review...
https://doi.org/10.1111/trf.14611
Transfusion Compernolle V, Chou ST et. al.

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

British Society for Histocompatibility & Immunogenetics and British Transplantation Soc...
https://doi.org/10.1111/j.1744-313X.2010.00955.x
International Journal of Immunogenetics; Howell WM, Harmer A et. al.

Jul 31st, 2010 - Ongoing technological developments in antibody detection and characterisation allowing relative quantitation of HLA-specific antibody levels, combined with crossmatch results, now allow a graded assessment of patient potential donor immunological ...

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Drugs  10 results see all →

Clinicaltrials.gov  3 results

Porcine Kidney Xenotransplantation in Patients With End-Stage Kidney Disease
https://clinicaltrials.gov/ct2/show/NCT05340426

Feb 16th, 2023 - Twenty patients with ESKD listed for kidney allotransplantation at UAB will be enrolled to receive either one or two porcine kidney xenotransplants from a 10-GE pig donor, contingent on the pig's overall size at the time of procurement. Recruitmen...

Cadaveric Islet Transplantation in Patients With Insulin-Dependent Diabetes Mellitus
https://clinicaltrials.gov/ct2/show/NCT00579371

Jun 15th, 2018 - We hypothesize that the following improvements to islet transplantation will increase the islet mass successfully isolated and allow for engraftment from a single pancreas. The improvements are: Using Two-Layer method preservation to improve pancr...

Collaborative Corneal Transplantation Studies (CCTS)
https://clinicaltrials.gov/ct2/show/NCT00000137

Sep 17th, 2009 - Approximately 20 percent of corneal transplant patients, about 6,000 per year, face donor tissue rejection at rates of up to 60 percent because of corneal vascularization or prior graft rejection. Histocompatibility antigen matching and/or crossma...

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News  6 results

Team Spirit Guides Gandara in Personalizing Care
https://www.onclive.com/view/team-spirit-guides-gandara-in-personalizing-care

Dec 5th, 2020 - David R. Gandara, MD Each morning, David R. Gandara, MD, wakes up energized to spend another day as an oncologist in lung cancer practice and research, a field in which advances have been more rapid than anything previously seen in oncology. As ...

Daratumumab Triplet Delays Progression in Multiple Myeloma
https://www.onclive.com/view/daratumumab-triplet-delays-progression-in-multiple-myeloma

Dec 4th, 2020 - Peter F. Lebowitz, MD, PhD Adding daratumumab (Darzalex) to standard bortezomib (Velcade) and dexamethasone improved progression-free survival (PFS) in patients with relapsed/refractory multiple myeloma enrolled in the phase III CASTOR (MMY3004) ...

FDA Approves Daratumumab for Pretreated Multiple Myeloma
https://www.onclive.com/view/fda-approves-daratumumab-for-pretreated-multiple-myeloma

Dec 4th, 2020 - Richard Pazdur, MD Acting 4 months ahead of schedule, the FDA has granted an accelerated approval to the CD38-targeted monoclonal antibody daratumumab (Darzalex) as a monotherapy for patients with multiple myeloma following at least 3 prior thera...

Team Spirit Guides Gandara in Personalizing Care
https://www.onclive.com/publications/oncology-live/2018/vol-19-no-13/team-spirit-guides-gandara-in-personalizing-care

Jun 30th, 2018 - David R. Gandara, MD Each morning, David R. Gandara, MD, wakes up energized to spend another day as an oncologist in lung cancer practice and research, a field in which advances have been more rapid than anything previously seen in oncology. As th...

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