About 10,112 results
Th2 cells promote eosinophil-independent pathology in a murine model of allergic bronch...
European Journal of Immunology; Dietschmann A, Schruefer S et. al.

Feb 27th, 2020 - Repeated inhalation of airborne conidia derived from the fungus Aspergillus fumigatus (Af) can lead to a severe eosinophil-dominated inflammatory condition of the lung termed allergic bronchopulmonary aspergillosis (ABPA). ABPA affects about 5 million individuals worldwide and the mechanisms regulating lung pathology in ABPA are poorly understood. Here, we used a mouse model of ABPA to investig...

Endoscopic management of eosinophilic esophagitis presenting as a double lumen esophagus.
Endoscopy Santiago Garcia J, Duffy J et. al.

Feb 27th, 2020 - Endoscopic management of eosinophilic esophagitis presenting as a double lumen esophagus.|2020|Santiago Garcia J,Duffy J,Ortiz-Fernandez-Sordo J,Budihal S,Parra-Blanco A,|

Validation of hepatitis C virus RNA detection using capillary blood by fingerprick (Gen...
Journal of Viral Hepatitis; Bielen R, Koc ÖM et. al.

Feb 27th, 2020 - To achieve the ambitious goals of the WHO to eliminate hepatitis C virus (HCV) infection as a public health threat by 2030, innovative approaches are needed to improve the uptake for screening and treatment in people who inject drugs (PWID). Important barriers to care are difficult venous access and the two-step approach in current point-of care tests, using an HCV antibody screening test follo...

Frontiers in Genitourinary Pathology.
Archives of Pathology & Laboratory Medicine; Huang J, Zhang L

Feb 26th, 2020 - This special section includes 4 articles as the proceedings of the Fifth Princeton Integrated Pathology Symposium (PIPS): Genitourinary Pathology, and an update on neuroendocrine tumor of the prostate. The symposium took place at the Princeton Medical Center, Plainsboro, New Jersey, on Sunday April 15, 2018. We hope again that this collection of outstanding reviews will serve as a handy referen...

High correlation between ethanol concentrations in post-mortem femoral blood and in alt...
Journal of Analytical Toxicology; Thelander G, Kugelberg FC et. al.

Feb 26th, 2020 - In connection with medicolegal autopsies peripheral blood (e.g. from a femoral vein) is the specimen of choice for toxicological analysis, although alternative specimens are also sometimes submitted, such as bile, cerebrospinal fluid (CSF), vitreous humor (VH), bladder urine, pleural effusions and/or lung fluid. Ethanol concentrations were determined in duplicate in femoral blood and in various...

Differences in Management of Eosinophilic Esophagitis in Europe: an Assessment of Curre...
Journal of Pediatric Gastroenterology and Nutrition; Tourlamain G, Garcia-Puig R et. al.

Feb 25th, 2020 - To assess differences in the diagnosis and management of Eosinophilic Esophagitis (EoE) by European pediatric (PG) and adult gastroenterologists (AG), and their self-reported adherence to guidelines. A multiple-choice questionnaire gauged the diagnostic and management strategies of gastroenterologists treating children or adults in 14 European countries and the United Arab Emirates (UAE). Quest...

Neuronal selectivity of botulinum neurotoxins.
Toxicon : Official Journal of the International Society on Toxinology; Poulain B, Lemichez E et. al.

Feb 25th, 2020 - Botulinum neurotoxins (BoNTs) are highly potent toxins responsible for a severe disease, called botulism. They are also efficient therapeutic tools with an increasing number of indications ranging from neuromuscular dysfunction to hypersecretion syndrome, pain release, depression as well as cosmetic application. BoNTs are known to mainly target the motor-neurons terminals and to induce flaccid ...

Prevalence of and mothers' knowledge, attitude and practice towards glucose-6-phosphate...
BMJ Open; Kasemy ZA, Bahbah WA et. al.

Feb 24th, 2020 - Neonatal jaundice (NNJ) is a frequent complication of glucose-6-phosphate dehydrogenase (G6PD) deficiency. To estimate the prevalence of G6PD deficiency among neonates with jaundice and to assess mothers' perception towards G6PD and NNJ. A cross-sectional study was carried out on 487 ethnic Egyptian neonates with indirect hyperbilirubinaemia from June 2018 to July 2019. The collected data inclu...

Trachealization of Esophagus: Eosinophilic Esophagitis.
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association; Paleti S, Hanson JA et. al.

Feb 23rd, 2020 - Trachealization of Esophagus: Eosinophilic Esophagitis.|2020|Paleti S,Hanson JA,Rustagi T,|

The key role of allergists-immunologists in the management of eosinophilic esophagitis.
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology; Spergel JM

Feb 23rd, 2020 - The key role of allergists-immunologists in the management of eosinophilic esophagitis.|2020|Spergel JM,|

Pathology and Multimodality Imaging of Acute and Chronic Femoral Stenting in Humans.
JACC. Cardiovascular Interventions; Kuntz SH, Torii S et. al.

Feb 20th, 2020 - The objective of this study was to comprehensively evaluate the pathology of acute and chronic femoral stenting in symptomatic atherosclerotic patients and to understand the causes of stent failure (SF) using multimodality imaging including micro-computed tomography. Although the pathology of coronary stenting has been well studied, the pathology of lower extremity femoral stenting remains poor...

Granulomatous Skin Diseases in a Tertiary Care Portuguese Hospital: A 10-Year Retrospec...
The American Journal of Dermatopathology; Queirós CS, Uva L et. al.

Feb 20th, 2020 - Granulomatous skin diseases comprise an extensive group of pathologies whose diagnosis usually requires a histopathological examination. At this level, various types of granulomas can be distinguished, namely tuberculoid, sarcoid, necrobiotic, suppurative, xanthogranuloma, and foreign-body granulomas. This study aimed to determine the frequency and pattern of different granulomatous skin lesion...

New methods for sex estimation using sternum and rib morphology.
International Journal of Legal Medicine; Peleg S, Pelleg Kallevag R et. al.

Feb 17th, 2020 - Sex estimation of skeletal remains is of great importance in the fields of physical and forensic anthropology. Since skeletons are often incomplete, it is essential to estimate sex from as many skeletal remains as possible. The aim of this study was to establish new methods for estimating sex using the morphology of the sternum and the fifth to ninth ribs. We considered two conditions of skelet...

Eosinophilic gastroenteritis: epidemiology, diagnosis, and treatment.
Current Opinion in Allergy and Clinical Immunology; Kinoshita Y, Ishihara S

Feb 17th, 2020 - Although several reviews concerning diagnosis and treatment of eosinophilic esophagitis (EoE) have been presented, there are few in regard to eosinophilic gastroenteritis (EGE). Fortunately, findings related to epidemiology, as well as diagnosis and treatment of this disease have recently been increasing. The rates of incidence of both EoE and EGE have been reported to be increasing. For accura...

Comorbid Occurrence of Eosinophilic Esophagitis and Inflammatory Bowel Disease.
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association; Sonnenberg A, Turner KO et. al.

Feb 13th, 2020 - Comorbid Occurrence of Eosinophilic Esophagitis and Inflammatory Bowel Disease.|2020|Sonnenberg A,Turner KO,Genta RM,|

Dietary treatment of eosinophilic gastrointestinal disorders in children.
Current Opinion in Clinical Nutrition and Metabolic Care; Gutiérrez-Junquera C, Zevit N

Feb 12th, 2020 - To provide an overview of recent developments on dietary treatment of eosinophilic gastrointestinal disorders (EGID) in children. Food antigens are the main triggers of eosinophilic esophagitis (EoE); however, currently available allergy tests cannot reliably identify eliciting antigens. Studies evaluating the six-food empiric elimination diet (6FED-milk, wheat/gluten, egg, soy/legumes, nuts an...

Potential of the zebrafish model for the forensic toxicology screening of NPS: A compar...
Neurotoxicology Morbiato E, Bilel S et. al.

Feb 12th, 2020 - The increased diffusion of the so-called novel psychoactive substances (NPS) and their continuous change in structure andconceivably activity has led to the need of a rapid screening method to detect their biological effects as early as possible after their appearance in the market. This problem is very felt in forensic pathology and toxicology, so the preclinical study is fundamental in the ap...

Eosinophilic esophagitis: comorbidities and atopic disease in Nevada.
Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus; Anderson J, Moonie S et. al.

Feb 11th, 2020 - Eosinophilic esophagitis (EoE) is a rare, immune-mediated illness. We aimed to examine the comorbidities and sensitization patterns associated with an EoE diagnosis in Nevada. The study goal was two-fold: to determine the most common EoE comorbidities and sequela in the state of Nevada using healthcare utilization records across all settings and to determine the most common food and aeroallerge...

Sleep manifestations, sleep architecture in children with Eosinophilic esophagitis pres...
Sleep Medicine; Siriwat R, Gurbani N et. al.

Feb 11th, 2020 - To describe sleep manifestations, polysomnographic (PSG) findings, and specific sleep disorders in children with Eosinophilic Esophagitis (EoE). This retrospective study included children with EoE who were referred to sleep clinics. Clinical manifestations, PSG variables, and diagnosis of sleep disorders were analyzed. Sleep architecture of patients with EoE was compared to control subjects. In...

Applying the Functional Luminal Imaging Probe to Esophageal Disorders.
Current Gastroenterology Reports; Donnan EN, Pandolfino JE

Feb 10th, 2020 - The functional luminal imaging probe (FLIP) uses high-resolution planimetry to provide a three-dimensional image of the esophageal lumen by measuring diameter, volume, and pressure changes. The goal of this review is to summarize the most recent advances in applying the (FLIP) to esophageal disorders. The FLIP has been studied in esophageal disease states including gastroesophageal reflux disea...