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About 69,793 results

ALLMedicine™ Asthma Center

Research & Reviews  23,970 results

A qualitative and quantitative comparison of IgE antibody profiles with two multiplex p...
https://doi.org/10.1111/cea.14016
Clinical and Experimental Allergy : Journal of the Britis... Scala E, Caprini E et. al.

Sep 16th, 2021 - Clinically complex phenotypes require more and more sophisticated and comprehensive diagnostic approaches, able to discriminate genuine sensitizations from cross-reactivity. Interpretative complexity of multiplex diagnostic arrays has somewhat lim...

Pharmacokinetics and Pharmacodynamics of Itepekimab in Healthy Adults and Patients With...
https://doi.org/10.1111/cts.13157
Clinical and Translational Science; Kosloski MP, Kalliolias GD et. al.

Sep 16th, 2021 - Itepekimab is a monoclonal antibody that targets interleukin-33 and has been shown to reduce airway inflammation and associated tissue damage in preclinical studies. We assessed the safety, tolerability, pharmacokinetics, and pharmacodynamic profi...

Time-Varying Association Between Severe Respiratory Syncytial Virus Infections and Subs...
https://doi.org/10.1093/infdis/jiab308
The Journal of Infectious Diseases; Wang X, Li Y et. al.

Sep 16th, 2021 - Early-life severe respiratory syncytial virus (RSV) infection has been associated with subsequent risk of asthma and recurrent wheeze. However, changes in the association over time and the interaction effect of the age at first RSV infection are l...

Physical Activity Among Urban Children with Asthma: Does Sleep Matter?
https://doi.org/10.1007/s10880-021-09815-y 10.1093/sleep/28.12.1568 10.1164/ajrccm.160.6.ats8-99 10.1093/jpepsy/jsq016 10.3109/09540269409023267 10.1183/13993003.00504-2018 10.1177/1367493512456109 10.1016/j.acap.2019.07.001 10.1016/j.acap.2011.05.006 10.1093/jpepsy/jsu025 10.1371/journal.pone.0204953 10.1186/s13102-019-0128-6 10.1164/rccm.200906-0836OC 10.1001/archpedi.152.12.1197 10.1542/peds.2006-1846 10.1155/2015/645645 10.1016/j.anai.2017.01.014 10.1093/jpepsy/jsv046 10.1016/j.sleh.2017.03.008 10.1016/j.sleh.2019.08.003 10.1093/jpepsy/jsl050 10.1542/peds.113.4.e341 10.1016/j.jaci.2006.12.662 10.1007/BF03404163 10.4172/2161-105X.1000232 10.1093/jpepsy/jsx052 10.1016/j.jaip.2014.02.005 10.1007/s11882-016-0609-6 10.1016/j.amepre.2013.11.001 10.1111/ijpo.12619 10.1542/peds.2008-2164 10.5664/jcsm.5866 10.1016/j.jaci.2018.02.004 10.1093/sleep/31.3.395 10.1016/j.jpeds.2006.04.061 10.1016/j.jpeds.2016.03.063 10.1038/sj.ijo.0801621 10.1249/MSS.0b013e318206476e 10.1002/ppul.1950150204 10.1136/bjsports-2012-091347 10.1249/01.mss.0000185292.71933.91 10.2165/00007256-200535020-00003 10.1111/pai.12670 10.3109/02770903.2015.1108435
Journal of Clinical Psychology in Medical Settings; D'Angelo C, Jelalian E et. al.

Sep 16th, 2021 - The present study examined associations between sleep and physical activity among a diverse sample of 97 urban children (ages 7-9) with persistent asthma. Differences in associations were evaluated by race/ethnicity and weight status. The extent t...

The Montelukast Therapy in Asthmatic Children with and without Food Allergy: Does It Ma...
https://doi.org/10.1159/000517865
International Archives of Allergy and Immunology; Sahiner UM, Arik Yilmaz E et. al.

Sep 15th, 2021 - Children with food allergy are at increased risk for asthma and asthma morbidity. Since leukotrienes are implicated in the pathogenesis of both asthma and probably in food allergies, we hypothesized that asthmatic children with concomitant food al...

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Guidelines  35 results

Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the Nation...
https://doi.org/10.1001/jama.2020.21974
JAMA Cloutier MM, Dixon AE et. al.

Dec 4th, 2020 - Asthma is a major public health problem worldwide and is associated with excess morbidity, mortality, and economic costs associated with lost productivity. The National Asthma Education and Prevention Program has released the 2020 Asthma Guideline...

Implementation of the Addendum Guidelines for Peanut Allergy Prevention by US allergist...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590504
The Journal of Allergy and Clinical Immunology; Johnson JL, Gupta RS et. al.

Aug 4th, 2020 - In 2017, the Addendum Guidelines for the Prevention of Peanut Allergy were published with recommendations on early introduction of peanut-containing foods based on infants' clinical history. We sought to conduct a nationwide US survey to assess Gu...

Adult Patients with Respiratory Distress: Current Evidence-based Recommendations for Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390576
The Western Journal of Emergency Medicine; Hodroge SS, Glenn M et. al.

Jul 30th, 2020 - We developed evidence-based recommendations for prehospital evaluation and treatment of adult patients with respiratory distress. These recommendations are compared with current protocols used by the 33 local emergency medical services agencies (L...

Considerations on biologicals for patients with allergic disease in times of the COVID-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300800
Allergy Vultaggio A, Agache I et. al.

Jun 6th, 2020 - The outbreak of the SARS-CoV-2-induced coronavirus disease 2019 (COVID-19) pandemic re-shaped doctor-patient interaction and challenged capacities of healthcare systems. It created many issues around the optimal and safest way to treat complex pat...

Managing Chronic Cough Due to Asthma and NAEB in Adults and Adolescents: CHEST Guidelin...
https://doi.org/10.1016/j.chest.2019.12.021
Chest Côté A, Russell RJ et. al.

Jan 24th, 2020 - Asthma and non-asthmatic eosinophilic bronchitis (NAEB) are among the commonest causes of chronic cough in adults. We sought to determine the role of non-invasive measurements of airway inflammation, including induced sputum and fractional exhaled...

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Drugs  859 results see all →

Clinicaltrials.gov  60 results

Small Airways Disease (SAD) in Severe Asthma as a Novel Endpoint and Distinct Target for Mepolizumab (SASAM Study)
https://clinicaltrials.gov/ct2/show/NCT05040997

Sep 10th, 2021 - Study hypothesis We hypothesize that mepolizumab has a significant beneficial effect on small airways disease in severe asthmatics and that the evaluation of small airways before and during treatment may represent a distinctive marker of response ...

Gamma MSC Asthma 21
https://clinicaltrials.gov/ct2/show/NCT05035862

Sep 5th, 2021 - Asthma affects one out of every 10 patients in the United States. Many of these patients have poor asthma symptom control. For example, patients with moderate-to-severe persistent asthma have ongoing symptoms and airway inflammation despite aggres...

Study of Mepolizumab-based Regimen Compared to Conventional Therapeutic Strategy in Patients With Eosinophilic Granulomatosis With Polyangiitis (E-merge)
https://clinicaltrials.gov/ct2/show/NCT05030155

Sep 1st, 2021 - Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is a rare systemic small-vessel vasculitis, associated with asthma and blood and tissue eosinophilia. EGPA belongs to the group of antineutrophil cytopla...

Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients
https://clinicaltrials.gov/ct2/show/NCT05019209

Aug 30th, 2021 - Atopic dermatitis (AD) is a chronic skin disease characterized by a relapsing course and typical clinical manifestation with itchy, eczematous lesions. The majority of AD patients reveals elevated IgE serum levels (> 100kU / L), which classifies t...

Telecounselling for Asthma Counseling
https://clinicaltrials.gov/ct2/show/NCT05021796

Aug 26th, 2021 - Asthma education is essential in improving outcomes in asthma management. Patients with asthma exacerbation frequently present to the urgent care centre or emergency department for emergency treatment. Nurse-led asthma education was considered as ...

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News  2,980 results

Benralizumab Promising for Severe, Chronic Rhinosinusitis With Nasal Polyps
https://www.medscape.com/viewarticle/954835

Jul 15th, 2021 - Benralizumab (Fasenra) significantly reduced nasal polyp score (NPS) and average nasal blockage score (NBS) compared with placebo for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) in a phase 3 trial. The randomized, multic...

Tezepelumab Reduces Asthma Exacerbation Rates by 56%
https://www.medscape.com/viewarticle/954777

Jul 14th, 2021 - The US Food and Drug Administration (FDA) has granted priority review for the biologic tezepelumab (AstraZeneca/Amgen) for treatment of severe asthma. The announcement was reported July 8, just days before the start of the European Academy of Alle...

Short-Acting Beta Agonist Overuse 'a Global Public Health Issue'
https://www.medscape.com/viewarticle/954587

Jul 11th, 2021 - About one third of asthma patients have high use of short-acting beta agonists (SABAs) in Europe across all severity levels, said Santiago Quirce, MD, PhD, with Hospital Universitario in Madrid, Spain. High use — defined as three or more canisters...

Dupilumab Safe, Effective in Kids 6-11 With Moderate-to-Severe Asthma
https://www.medscape.com/viewarticle/954586

Jul 10th, 2021 - Dupilumab (Dupixent, Sanofi and Regeneron) significantly reduced exacerbations compared with placebo in children ages 6-11 years who had moderate-to-severe asthma in a phase 3 trial. A fully human monoclonal antibody, dupilumab also improved lung ...

Fast Five Quiz: Severe Asthma Management
https://reference.medscape.com/viewarticle/951633

Jul 7th, 2021 - Asthma is a common, chronic inflammatory disorder of the airways characterized by shortness of breath, wheezing, coughing, chest tightness, variable airflow limitation, and tissue remodeling. Nearly 400 million people around the world have asthma,...

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Patient Education  13 results see all →