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ALLMedicine™ Developmental Disorders Center

Research & Reviews  1,263 results

Structural and functional specificity of H3K36 methylation.
https://doi.org/10.1186/s13072-022-00446-7 10.1038/nrm3382 10.1038/38444 10.1007/s10577-005-1024-3 10.1016/j.molcel.2017.04.012 10.1073/pnas.1920725117 10.1146/annurev.biochem.75.103004.142422 10.1038/47412 10.1126/science.1063127 10.1016/j.biosystems.2017.11.005 10.1002/em.21830 10.1093/nar/gky245 10.1038/emboj.2010.329 10.1007/s10577-012-9288-x 10.1016/j.cell.2016.07.005 10.1016/j.celrep.2017.08.058 10.1093/nar/gkx1276 10.1038/s41375-019-0456-2 10.1093/emboj/cdg288 10.1186/1476-4598-5-26 10.1016/j.gene.2007.04.027 10.1073/pnas.0906831106 10.1074/jbc.M109.034462 10.1016/j.molcel.2011.08.042 10.1074/jbc.M808431200 10.1074/jbc.M110.203307 10.1038/nrm3274 10.1186/s13578-020-0374-z 10.1074/jbc.M110.204115 10.1073/pnas.1002653107 10.1128/MCB.00993-07 10.1007/s00018-017-2517-x 10.1093/nar/gkw008 10.1128/MCB.22.5.1298-1306.2002 10.1002/wdev.109 10.1128/MCB.25.8.3305-3316.2005 10.1074/jbc.C500423200 10.1038/s41586-019-1517-4 10.1002/jcp.26836 10.1038/s41588-019-0398-7 10.1101/cshperspect.a026468 10.1038/s41388-018-0429-3 10.7150/jca.38391 10.2741/4834 10.1038/s41419-020-2266-x 10.1080/15476286.2016.1144009 10.1172/JCI94292 10.1186/s13059-017-1235-x 10.1093/nar/gkw814 10.1016/j.celrep.2017.05.057 10.1158/1078-0432.CCR-12-3886 10.18632/oncotarget.9368 10.5582/bst.2016.01228 10.1016/j.biocel.2021.106155 10.1007/s00401-013-1095-8 10.1158/0008-5472.CAN-10-0120 10.1074/jbc.M116.739375 10.1038/s41467-018-04329-y 10.7554/eLife.02482 10.1038/nsmb.2314 10.1371/journal.pgen.1002717 10.1038/nsmb.2796 10.3389/fgene.2014.00296 10.1038/nsmb.2866 10.1073/pnas.1620208114 10.1038/s41467-021-21663-w 10.3390/genes9010009 10.1038/s41571-020-0350-x 10.1101/gr.158253.113 10.1016/j.ccell.2015.09.015 10.1242/jcs.226969 10.1021/ja307060p 10.1038/s41467-019-11726-4 10.1128/EC.4.8.1455-1464.2005 10.1073/pnas.0506350102 10.1093/nar/gkv393 10.1128/MCB.00001-08 10.1101/gad.1700008 10.1093/hmg/7.9.1463 10.4161/cc.10.16.17113 10.1074/jbc.M116.720748 10.1158/0008-5472.CAN-13-1000 10.1016/j.febslet.2009.05.038 10.1038/s41467-018-07511-4 10.1080/1354750X.2020.1734861 10.1073/pnas.97.13.7284 10.4155/fmc-2016-0071 10.1186/s13046-019-1462-y 10.1126/sciadv.abg7444 10.1186/s13027-021-00347-6 10.1080/21655979.2021.2009963 10.1038/ncb1608 10.1016/j.bbrc.2008.12.093 10.3389/fonc.2020.600514 10.1016/j.bbrc.2019.08.020 10.1016/j.molcel.2021.08.034 10.2147/CMAR.S222673 10.1158/1541-7786.MCR-14-0292-T 10.3324/haematol.13426 10.1038/s41419-021-04267-6 10.1038/s41388-021-01747-z 10.1038/s42003-020-01186-8 10.1038/s41419-019-1347-1 10.1038/s41467-019-12811-4 10.1038/leu.2013.204 10.1038/s41467-021-26913-5 10.1158/1541-7786.MCR-20-0092 10.1158/1538-7445.AM2021-1106 10.1007/s10549-017-4258-9 10.2147/OTT.S191732 10.1038/s41419-021-04205-6 10.1038/s41586-020-03170-y 10.3892/or.2017.5936 10.1093/jmcb/mjz098 10.1073/pnas.1314608110 10.1038/s41586-020-03069-8 10.1038/s41467-017-01080-8 10.3389/fonc.2021.754093 10.1158/2159-8290.CD-16-0058 10.1038/ng.3547 10.1210/jc.2014-2280 10.18632/oncotarget.2967 10.1038/ncomms10207 10.1038/sj.ejhg.5201050 10.1038/s41586-019-1534-3 10.1093/hmg/ddac026 10.1038/s41439-021-00151-z 10.1007/s13258-021-01091-2 10.1002/glia.23867 10.1101/mcs.a004044 10.1038/s41436-021-01158-1 10.1038/srep26597 10.1186/s13039-020-00483-5 10.1038/s41598-019-43458-2 10.3390/genes12071053 10.1002/ajmg.a.38193 10.1016/j.cell.2019.12.036 10.1016/j.ejmg.2018.05.003 10.1038/s41380-019-0642-7 10.1101/gad.284323.116 10.1038/ng.2699 10.1038/s42003-020-01223-6 10.1038/s41421-021-00261-6 10.1016/j.str.2019.01.016 10.1242/dev.163808 10.1186/gb-2005-6-8-227 10.1016/j.cell.2006.07.026 10.1038/nature08448 10.1093/nar/gkx1010 10.1128/MCB.01229-09 10.1111/j.1365-2443.2011.01573.x 10.1074/jbc.M109.085043 10.1016/j.celrep.2020.107751 10.1074/jbc.M111.273953 10.1038/srep43906 10.1146/annurev.biophys.34.040204.144452 10.1074/jbc.M410483200 10.1126/science.1184208 10.1074/jbc.M806564200 10.1038/nsmb.2449 10.1016/j.tips.2013.11.005 10.1016/j.tcb.2009.02.003 10.1038/nrm2298 10.1016/j.molcel.2011.03.025 10.1073/pnas.1819029116 10.1074/jbc.M110.194027 10.1016/j.celrep.2019.12.060 10.7554/eLife.41497 10.1016/j.celrep.2012.09.020 10.1242/dev.095786 10.1016/j.celrep.2020.108390 10.1371/journal.pgen.1004566 10.1016/j.cell.2012.09.002 10.7554/eLife.61964 10.1038/nature10833 10.1126/science.1232245 10.1038/ng.2814 10.1371/journal.pone.0152673 10.1016/j.jmb.2018.04.014 10.1016/j.cell.2007.05.009 10.1016/j.cell.2005.06.026 10.1038/nature11326 10.1371/journal.pbio.0030328 10.1016/j.cell.2005.01.001 10.1128/MCB.25.21.9447-9459.2005 10.1016/j.celrep.2014.12.027 10.1371/journal.pgen.1001173 10.1074/jbc.M116.718742 10.1126/science.1124000 10.1093/emboj/cdg248 10.1186/gb-2008-9-11-r167 10.1038/ncomms13610 10.1038/emboj.2012.221 10.1038/nature06561 10.15698/mic2020.03.711 10.1038/nsmb1239 10.1128/MCB.01068-13 10.1038/embor.2012.146 10.1016/j.cell.2009.02.004 10.1007/s00294-019-00962-2 10.1016/j.molcel.2017.05.026 10.1534/genetics.116.199422 10.1038/hdy.2010.44 10.1016/j.jmb.2019.09.006 10.1128/jb.135.3.1156-1157.1978 10.1021/ac301727c 10.1093/nar/23.2.203 10.1016/j.jsb.2016.03.013 10.1038/nature14176 10.1073/pnas.2021795118 10.1093/nar/18.19.5735 10.1016/S0021-9258(17)32497-3 10.1038/cr.2017.31 10.1016/j.canlet.2017.08.030 10.1186/s13045-019-0805-7 10.1038/nature11112 10.1016/j.cell.2012.05.003 10.1038/nchembio.1432 10.1016/j.cell.2014.08.005 10.1038/s41586-019-1016-7 10.1038/nature18298 10.1093/molbev/msy096
Epigenetics & Chromatin; Lam UTF, Tan BKY et. al.

May 18th, 2022 - The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function mutations ...

Dorsal visual stream activity during coherent motion processing is not related to math ...
NeuroImage. Clinical; Laws ML, Matejko AA et. al.

May 18th, 2022 - Math disability (MD) or developmental dyscalculia is a highly prevalent learning disability involving deficits in computation and arithmetic fact retrieval and is associated with dysfunction of parietal and prefrontal cortices. It has been suggest...

Cellular protrusions in 3D: Orchestrating early mouse embryogenesis.
Seminars in Cell & Developmental Biology; Omelchenko T

May 17th, 2022 - Cellular protrusions generated by the actin cytoskeleton are central to the process of building the body of the embryo. Problems with cellular protrusions underlie human diseases and syndromes, including implantation defects and pregnancy loss, co...

The electrophysiological markers of hyperacusis: a scoping review.
International Journal of Audiology; Bigras C, Villatte B et. al.

May 14th, 2022 - Hyperacusis is known as a reduced tolerance to sounds perceived as normal to the majority of the population. There is currently no agreed definition, diagnostic tool, or objective measure of its occurrence. The purpose of this review is to catalog...

Study of Parental Stress and Care Consumption Until 24 Months Corrected Age of Infants at a High Risk of Developmental Delay, After Discharge From Neonatal Intensive Care

May 10th, 2022 - Cerebral palsy (CP) is the leading cause of motor disability in children, affecting 125,000 people in France and with 1800 new cases per year. Prematurity remains a major risk factor, although children born at term represent 52% of children with c...

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Clinicaltrials.gov  31 results

Study of Parental Stress and Care Consumption Until 24 Months Corrected Age of Infants at a High Risk of Developmental Delay, After Discharge From Neonatal Intensive Care

May 10th, 2022 - Cerebral palsy (CP) is the leading cause of motor disability in children, affecting 125,000 people in France and with 1800 new cases per year. Prematurity remains a major risk factor, although children born at term represent 52% of children with c...

Biomarker-Driven Pharmacological Treatment of Adolescents With Autism Spectrum Disorder With Gabapentin

Apr 12th, 2022 - Outline of Research Plan The investigators will recruit 40 adolescents with ASD (age 13-17) to participate in an 8-week open label clinical trial of gabapentin, with wraparound neuroimaging to assess the primary outcome of Aim 1 (response of RAI G...

Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities. CHROmosome MAPping and Sequencing (CHROMA...

Mar 22nd, 2022 - Chromosome aberrations are found in up to 1% of the general population. Structural aberrations, either balanced (3.6‰) or unbalanced (0.9‰), represent a third of them. Most (but not all) unbalanced anomalies are associated with a relevant phenotyp...

NEURodevelopmental Outcome After Persistent Pulmonary Hypertension Of the Newborn

Nov 23rd, 2021 - Neonatal pulmonary hypertension is a rare but serious condition resulting from a lack of adaptation to extra-uterine life in some newborns. In the short term, the risk of death requires rapid and appropriate management of this transient pathology....

Brain Plasticity Underlying Acquisition of New Organizational Skills in Children

Oct 5th, 2021 - Organizational, time management and planning (OTMP) skills deficits are impairing features of developmental disorders, such as Attention Deficit Hyperactive Disorder (ADHD), which compromise school performance and family relations. The manualized ...

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News  109 results


ADHD (attention-deficit/hyperactivity disorder) is one of the most common childhood developmental disorders and often lasts into adulthood.

Magnitude of Mortality Increase in People With Psychiatric Disorders During the Pandemic

Oct 11th, 2021 - People with mental health conditions have been disproportionately affected by the COVID-19 pandemic, according to research published in  The Lancet Regional Health – Europe . The findings suggest that the pandemic has exacerbated pre-existing heal...

Twofold Increased Risk for Death From COVID-19 in Psych Patients

Jul 22nd, 2021 - Patients with a mental illness, particularly a psychotic or mood disorder, are twice as likely to die after infection with SARS-CoV-2 compared with those without a psychiatric diagnosis, according to the results of the largest study of its kind to...

A Quick Tour of the New Lyme Disease Guideline

Jun 14th, 2021 - This transcript has been edited for clarity. Hello. This is Paul Auwaerter for Medscape Infectious Diseases, speaking from Johns Hopkins University School of Medicine. Spring is in full swing and tick season has certainly returned. I thought I wou...

New 'Atlas' Maps Links Between Mental Disorders, Physical Illnesses

May 11th, 2020 - Mental illnesses are associated with a significantly increased risk of subsequent physical diseases, new research shows. An international team of researchers has created an 'atlas' that maps the relationship between specific mental disorders and t...

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Patient Education  2 results see all →