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ALLMedicine™ Developmental Disorders Center

Research & Reviews  1,263 results

Structural and functional specificity of H3K36 methylation.
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Epigenetics & Chromatin; Lam UTF, Tan BKY et. al.

May 18th, 2022 - The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function mutations ...

Dorsal visual stream activity during coherent motion processing is not related to math ...
https://doi.org/10.1016/j.nicl.2022.103042
NeuroImage. Clinical; Laws ML, Matejko AA et. al.

May 18th, 2022 - Math disability (MD) or developmental dyscalculia is a highly prevalent learning disability involving deficits in computation and arithmetic fact retrieval and is associated with dysfunction of parietal and prefrontal cortices. It has been suggest...

Cellular protrusions in 3D: Orchestrating early mouse embryogenesis.
https://doi.org/10.1016/j.semcdb.2022.05.005
Seminars in Cell & Developmental Biology; Omelchenko T

May 17th, 2022 - Cellular protrusions generated by the actin cytoskeleton are central to the process of building the body of the embryo. Problems with cellular protrusions underlie human diseases and syndromes, including implantation defects and pregnancy loss, co...

The electrophysiological markers of hyperacusis: a scoping review.
https://doi.org/10.1080/14992027.2022.2070083
International Journal of Audiology; Bigras C, Villatte B et. al.

May 14th, 2022 - Hyperacusis is known as a reduced tolerance to sounds perceived as normal to the majority of the population. There is currently no agreed definition, diagnostic tool, or objective measure of its occurrence. The purpose of this review is to catalog...

Study of Parental Stress and Care Consumption Until 24 Months Corrected Age of Infants at a High Risk of Developmental Delay, After Discharge From Neonatal Intensive Care
https://clinicaltrials.gov/ct2/show/NCT05233371

May 10th, 2022 - Cerebral palsy (CP) is the leading cause of motor disability in children, affecting 125,000 people in France and with 1800 new cases per year. Prematurity remains a major risk factor, although children born at term represent 52% of children with c...

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Clinicaltrials.gov  31 results

Study of Parental Stress and Care Consumption Until 24 Months Corrected Age of Infants at a High Risk of Developmental Delay, After Discharge From Neonatal Intensive Care
https://clinicaltrials.gov/ct2/show/NCT05233371

May 10th, 2022 - Cerebral palsy (CP) is the leading cause of motor disability in children, affecting 125,000 people in France and with 1800 new cases per year. Prematurity remains a major risk factor, although children born at term represent 52% of children with c...

Biomarker-Driven Pharmacological Treatment of Adolescents With Autism Spectrum Disorder With Gabapentin
https://clinicaltrials.gov/ct2/show/NCT05063656

Apr 12th, 2022 - Outline of Research Plan The investigators will recruit 40 adolescents with ASD (age 13-17) to participate in an 8-week open label clinical trial of gabapentin, with wraparound neuroimaging to assess the primary outcome of Aim 1 (response of RAI G...

Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities. CHROmosome MAPping and Sequencing (CHROMA...
https://clinicaltrials.gov/ct2/show/NCT05290051

Mar 22nd, 2022 - Chromosome aberrations are found in up to 1% of the general population. Structural aberrations, either balanced (3.6‰) or unbalanced (0.9‰), represent a third of them. Most (but not all) unbalanced anomalies are associated with a relevant phenotyp...

NEURodevelopmental Outcome After Persistent Pulmonary Hypertension Of the Newborn
https://clinicaltrials.gov/ct2/show/NCT04841070

Nov 23rd, 2021 - Neonatal pulmonary hypertension is a rare but serious condition resulting from a lack of adaptation to extra-uterine life in some newborns. In the short term, the risk of death requires rapid and appropriate management of this transient pathology....

Brain Plasticity Underlying Acquisition of New Organizational Skills in Children
https://clinicaltrials.gov/ct2/show/NCT04108273

Oct 5th, 2021 - Organizational, time management and planning (OTMP) skills deficits are impairing features of developmental disorders, such as Attention Deficit Hyperactive Disorder (ADHD), which compromise school performance and family relations. The manualized ...

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News  109 results

ADHD
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/428100

ADHD (attention-deficit/hyperactivity disorder) is one of the most common childhood developmental disorders and often lasts into adulthood.

Magnitude of Mortality Increase in People With Psychiatric Disorders During the Pandemic
https://www.medscape.com/viewarticle/960680

Oct 11th, 2021 - People with mental health conditions have been disproportionately affected by the COVID-19 pandemic, according to research published in  The Lancet Regional Health – Europe . The findings suggest that the pandemic has exacerbated pre-existing heal...

Twofold Increased Risk for Death From COVID-19 in Psych Patients
https://www.medscape.com/viewarticle/955237

Jul 22nd, 2021 - Patients with a mental illness, particularly a psychotic or mood disorder, are twice as likely to die after infection with SARS-CoV-2 compared with those without a psychiatric diagnosis, according to the results of the largest study of its kind to...

A Quick Tour of the New Lyme Disease Guideline
https://www.medscape.com/viewarticle/951589

Jun 14th, 2021 - This transcript has been edited for clarity. Hello. This is Paul Auwaerter for Medscape Infectious Diseases, speaking from Johns Hopkins University School of Medicine. Spring is in full swing and tick season has certainly returned. I thought I wou...

New 'Atlas' Maps Links Between Mental Disorders, Physical Illnesses
https://www.medscape.com/viewarticle/930313

May 11th, 2020 - Mental illnesses are associated with a significantly increased risk of subsequent physical diseases, new research shows. An international team of researchers has created an 'atlas' that maps the relationship between specific mental disorders and t...

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Patient Education  2 results see all →