ALLMedicine™ Precocious Puberty Center

May 14th, 2022 - We report the challenging case of a 6-year-old boy with precocious puberty related to histologically proven Leydig cell tumor. Multiparametric ultrasound and magnetic resonance imaging (MRI) was performed. Interesting findings were scarcely or nev...

May 13th, 2022 - Androgen excess in childhood results in pseudoprecocious puberty, accelerated childhood growth with premature epiphyseal fusion, adult short stature, and unknown metabolic and psychological perturbations. Congenital adrenal hyperplasia (CAH) and f...

Apr 24th, 2022 - In the COVID-19 pandemic, there was an increase in consultations for precocious puberty. We aim to analyze differences in female puberty before and during the COVID-19 pandemic. A cross-sectional analytical study was designed at the Pediatric Endo...

Apr 22nd, 2022 - The drug being tested in this study is called leuprorelin acetate depot 3M. Leuprorelin acetate depot 3M will be tested to treat children who have central precocious puberty. This study will look at the efficacy and safety of leuprorelin acetate d...

Apr 22nd, 2022 - Patients with childhood brain tumors are at risk of endocrine disorders. The prevalence of endocrine disorders varies across the world but is unknown in Malaysia. This study's objectives were to determine the prevalence of endocrine disorders amon...

May 13th, 2022 - Androgen excess in childhood results in pseudoprecocious puberty, accelerated childhood growth with premature epiphyseal fusion, adult short stature, and unknown metabolic and psychological perturbations. Congenital adrenal hyperplasia (CAH) and f...

Apr 22nd, 2022 - The drug being tested in this study is called leuprorelin acetate depot 3M. Leuprorelin acetate depot 3M will be tested to treat children who have central precocious puberty. This study will look at the efficacy and safety of leuprorelin acetate d...

Apr 13th, 2022 - The purpose of the protocol is to assess the efficacy of the triptorelin 6 month PR (Prolonged Release) formulation in suppressing LH (Luteinising hormone) levels to prepubertal levels (defined as a peak LH ≤5 IU/L) after i.v. GnRH (Gonadotropin-r...

Mar 31st, 2022 - The primary objective of the study is to assess the safety and efficacy of a leuprolide acetate (LA) 45 mg 6-month depot formulation for the treatment of CPP in children who are either naïve to treatment with a gonadotropin-releasing hormone agoni...

Mar 22nd, 2022 - For patients enter extension phase, two additional Triptorelin injections will be given at month 6 and month 9 visits.

Nov 10th, 2021 - Sudeep Taksali thought he'd won his battle to avoid a steep price tag on a medicine for his daughter. He was wrong. Dr Sudeep Taksali In 2020, he'd fought to get insurance to cover a lower-priced version of a drug his then-8-year-old needed. She'd...

May 7th, 2021 - Cannabidiol (CBD), purchased online, has been linked to early puberty in a very young child with severe intractable epilepsy. The case report describes the unusual instance of a 2-year-old boy with severe, uncontrolled epilepsy who was treated wit...

May 3rd, 2021 - NEW YORK (Reuters Health) - Researchers from the U.K. are reporting a case of early puberty in a 2-year-old boy who was given cannabidiol (CBD) oil his mother purchased online to help control epileptic seizures. The start of puberty before the age...

Apr 28th, 2021 - Point: Bans on Pediatric Transgender/Gender-Nonconforming Care Are Anti-science, Anti-family, Anti-American Elyse D. Pine, MD Seven years ago, in my pediatric endocrine practice, I met a smart, kind, but anxious child who was assigned female at bi...

Mar 12th, 2021 - Children who have been treated for brain tumors often experience significant weight gain, and new findings suggest that this could be a sign of hypothalamic-pituitary (HP) dysfunction. "We believe that endocrine surveillance should be initiated ea...