About 266 results
Causes and Evaluation of Chronic Dyspnea

Jul 11th, 2015 - Chronic dyspnea is shortness of breath that lasts more than one month. The perception of dyspnea varies based on behavioral and physiologic responses. Dyspnea that is greater than expected with the degree of exertion is a symptom of disease. Most cases of dyspnea result from asthma, heart failure and myocardial ischemia, chronic obstructive pulmonary disease, interstitial lung disease, pneumoni...

Guidelines for the Use of Iron Supplements to Prevent and Treat Iron Deficiency Anemia

Jan 1st, 1998 - Iron deficiency anemia is the most common micronutrient deficiency in the world today. It impacts the lives of millions of women and children contributing to poor cognitive development, increased maternal mortality and decreased work capacity. Yet with appropriate public health action, this form of micronutrient malnutrition can be brought under control. These guidelines are offered as an imp...

Replacement meals boost nutrient intake by pregnant women with obesity

Dec 27th, 2019 - The secondary micronutrient analysis that Dr. Phelan reported documented the high prevalence of micronutrient deficiencies among the study participants at baseline.

Choosing Wisely: 5 Recommendations on Testing to Avoid in Pediatric Hematology

Dec 10th, 2019 - ORLANDO, Florida — There's a new Choosing Wisely list in hematology focused specifically on children, with five tests or procedures that experts advise should be avoided, with some exceptions. The list, which was produced by an expert panel with representatives from the American Society of Hematology and the American Society of Pediatric Hematology/Oncology (ASPHO), includes five tests or proce...

Think twice: Choosing Wisely recommendations on testing to avoid in pediatric hematology

Dec 10th, 2019 - Previous studies on the platelet transfusions in patients with hematologic malignancies have shown that 10,000/mcL is the appropriate threshold, with no difference in bleeding above that number and increased bleeding below it, Dr. Bercovitz said.

FDA OKs Asthma Drug Benralizumab (Fasenra) for At-Home Use

Oct 3rd, 2019 - The US Food and Drug Administration has approved a self-administered version of benralizumab (Fasenra, AstraZeneca), which comes in a prefilled, single-use autoinjector (Fasenra Pen), the company has announced. Benralizumab is an antieosinophil humanized monoclonal antibody that selectively targets the interleukin-5 receptor expressed on the surface of eosinophils. Since 2017, it has been avail...

Anemia in Early Pregnancy Linked to Autism, ADHD, Intellectual Disability in Kids

Sep 23rd, 2019 - Iron deficiency anemia early in pregnancy appears to increase the risk of neurodevelopmental disorders, including autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and intellectual disability (ID) in offspring. Results of a large population-based study showed the risk of ASD and ADHD in children whose mothers had anemia in early pregnancy was 44% and 37% higher, r...

Anemia in early pregnancy linked with risk for neurodevelopmental disorders

Sep 20th, 2019 - Children born to mothers with iron-deficiency anemia early in pregnancy may be at higher risk for neurodevelopmental disorders, a new study suggests. In an analysis of data on more than half a million babies born in Sweden, researchers found that anemia in the mother before the 30th week of pregnancy was linked with a heightened risk of disorders including autism, ADHD and intellectual disabili...

Benralizumab trials cast doubt on eosinophil depletion’s role in COPD treatment

Sep 12th, 2019 - Depletion of eosinophils in blood and sputum By week 4, benralizumab substantially depleted blood eosinophils. In addition, treatment substantially depleted sputum eosinophils by week 24.

Penicillin-susceptible Streptococcus pneumoniae most common cause of bacteremic CAP
Jill D. Pivovarov, MDedge News

Jun 24th, 2019 - A study found that only 2% of children hospitalized with community-acquired pneumonia (CAP) actually had any causative pathogen in their blood culture results, despite national guidelines that recommend blood cultures for all children hospitalized with moderate to severe CAP. CDC/Dr.

A better approach to the diagnosis of PE
MDedge Family Medicine; Andrew H. Slattengren, DO, Shailendra Prasad, MBBS, MPH et. al.

Jun 10th, 2019 - ILLUSTRATIVE CASE Penny E is a 48-year-old woman with a history of asthma who presents with wheezing and respiratory distress. There are no clinical signs of deep vein thrombosis or hemoptysis.

Eosinophil levels affect glucocorticoid response in mild, persistent asthma
Will Pass, MDedge News

May 19th, 2019 - Patients with mild asthma who rely solely on short-acting beta2-agonists (SABAs) to control their asthma symptoms remain at increased risk of exacerbations, according to investigators. Two recent studies presented at the American Thoracic Society’s international conference demonstrated the benefits of glucocorticoid therapy among patients with mild persistent or intermittent asthma while highli.

Master trial seeks to aid drug development for pediatric AML
Jennifer Smith

May 12th, 2019 - NEW ORLEANS – Researchers are organizing a master trial in an attempt to improve the treatment of pediatric acute myeloid leukemia (AML). The Pediatric Acute Leukemia (PedAL) trial is an effort to collect data on all pediatric AML patients.

Researchers to be honored at ASPHO
Jennifer Smith

Apr 22nd, 2019 - Several hematology and oncology researchers will receive awards at the 2019 conference of the American Society of Pediatric Hematology/Oncology (ASPHO), which takes place May 1-4. Dr.

Vitamins in Early Pregnancy and Autism Risk

Feb 27th, 2019 - Autism was less likely to recur in high-risk families when mothers took prenatal vitamins -- particularly folic acid and perhaps iron as well -- in the first month of their pregnancy, an analysis of MARBLES study data found. Of 241 children with older siblings who had autism spectrum disorder (ASD), those whose mothers took prenatal vitamins during the first month were half as likely to receive...

Tranexamic acid shows improvements in heavy menstrual bleeding
Bianca Nogrady

Feb 13th, 2019 - The antifibrinolytic drug tranexamic acid appears to significantly improve quality of life for young women who experience heavy menstrual bleeding, new research suggests. Writing in the Journal of Pediatric & Adolescent Gynecology, Sarah H.

Benralizumab maintains effectiveness in severe asthma at 2 years
Jim Kling

Jan 10th, 2019 - Benralizumab is safe and effective for the treatment of uncontrolled asthma out to 2 years, according findings of the BORA trial, an extension study of the phase 3 SIROCCO and CALIMA trials. The study follows up and reinforces previously reported 1-year data and was reported by William W.

Morning Break: Vaccine Skeptic in the House; 'Iron Man' Clinics; Tampon Recall

Dec 13th, 2018 - Note that some links may require subscriptions. Tennessee's controversial congressman-elect Mark Green, MD, suggested that the CDC is "fraudulently" withholding information on vaccine research that may show a link to autism, the Nashville Tennessean reported. Fentanyl is already killing thousands of Americans, but could it be used to kill millions? A Bloomberg investigation has a discomfiting a...

Emapalumab safe, effective in pediatric primary hemophagocytic lymphohistiocytosis
Andrew D. Bowser

Dec 4th, 2018 - SAN DIEGO – Emapalumab, an interferon gamma-blocking antibody, controls disease activity and has a favorable safety profile in patients with primary hemophagocytic lymphohistiocytosis (HLH), according to Franco Locatelli, MD, of the department of pediatric hematology and oncology at Ospedale Pediatrico Bambino Gesù, Rome. Andrew D.

Similar Rates of Fetal Growth Restriction Seen With Two Popular Bariatric Procedures

Aug 15th, 2018 - NEW YORK (Reuters Health) - Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) appear to result in similar rates of fetal growth restriction, according to French researchers. "Our study is the first clearly showing that SG induces the same fetal growth restriction as RYGB," the team note in Surgery for Obesity and Related Diseases, online July 20. In their study, they found fetal growt...