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About 14,976 results

ALLMedicine™ Pertussis Center

Research & Reviews  6,677 results

Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection.
https://doi.org/10.1186/s12879-021-06090-y
BMC Infectious Diseases; Jiang W, Wei C et. al.

May 4th, 2021 - The prevalent resurgence of pertussis has recently become a critical public health problem worldwide. To understand pertussis pathogenesis and the host response to both the pathogen and vaccines, a suitable pertussis animal model, particularly a n...

Pertussis vaccine effectiveness and duration of protection - A systematic review and me...
https://doi.org/10.1016/j.vaccine.2021.04.032
Vaccine Wilkinson K, Righolt CH et. al.

May 3rd, 2021 - A comprehensive review of observational pertussis vaccine effectiveness (VE) studies is needed to update gaps from previous reviews. We conducted a systematic review of VE and duration of protection studies for the whole-cell (wP) and acellular (a...

Characterization of a Rat Model of Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody...
https://doi.org/10.1159/000515421
Nephron Cerullo D, Rottoli D et. al.

Apr 28th, 2021 - Necrotizing crescentic glomerulonephritis (GN) associated with anti-neutrophil cytoplasmic antibodies (ANCA) against myeloperoxidase (MPO) is a devastating disease that quickly progresses to kidney failure. Current therapies are broadly immunosupp...

Bacterial RTX toxins and host immunity.
https://doi.org/10.1097/QCO.0000000000000726
Current Opinion in Infectious Diseases; Ahmad JN, Sebo P

Apr 26th, 2021 - RTX toxin action often defines the outcome of bacterial infections. Here, we discuss the progress in understanding the impacts of RTX toxin activities on host immunity. Bordetella pertussis CyaA activity paralyzes sentinel phagocytic cells by elev...

Construction and evaluation of a pertactin-deficient live attenuated pertussis vaccine ...
https://doi.org/10.1016/j.vaccine.2021.04.014
Vaccine Solans L, Debrie AS et. al.

Apr 26th, 2021 - Pertussis, mainly caused by Bordetella pertussis, is a severe respiratory disease that can be fatal, especially in young infants. Vaccines, massively implemented since the middle of the last century, have substantially reduced the pertussis incide...

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Guidelines  37 results

Licensure of a Diphtheria and Tetanus Toxoids and Acellular Pertussis, Inactivated Poli...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004397
MMWR. Morbidity and Mortality Weekly Report; Oliver SE, Moore KL

Feb 6th, 2020 - On December 21, 2018 the Food and Drug Administration (FDA) licensed a hexavalent combined diphtheria and tetanus toxoids and acellular pertussis (DTaP) adsorbed, inactivated poliovirus (IPV), Haemophilus influenzae type b (Hib) conjugate (meningo...

Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccines: Upd...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367039
MMWR. Morbidity and Mortality Weekly Report; Havers FP, Moro PL et. al.

Jan 23rd, 2020 - Since 2005, a single dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine has been recommended by the Advisory Committee on Immunization Practices (ACIP) for adolescents and adults (1,2). After receipt of Tdap,...

Genomic Survey of Bordetella pertussis Diversity, United States, 2000–2013
https://wwwnc.cdc.gov/eid/article/25/4/18-0812_article
Emerging Infectious Diseases; Weigand,M.,et al

Mar 12th, 2019 - We characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurri...

Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919600
MMWR. Recommendations and Reports : Morbidity and Mortali... Liang JL, Tiwari T et. al.

Apr 27th, 2018 - This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria, and pertussis in the United States. As a comprehensive summary of previ...

Committee Opinion No. 718 Summary: Update on Immunization and Pregnancy: Tetanus, Dipht...
https://doi.org/10.1097/AOG.0000000000002293
Obstetrics and Gynecology;

Aug 23rd, 2017 - The overwhelming majority of morbidity and mortality attributable to pertussis infection occurs in infants who are 3 months and younger. Infants do not begin their own vaccine series against pertussis until approximately 2 months of age. This leav...

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Drugs  55 results see all →

Clinicaltrials.gov  7,297 results

Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection.
https://doi.org/10.1186/s12879-021-06090-y
BMC Infectious Diseases; Jiang W, Wei C et. al.

May 4th, 2021 - The prevalent resurgence of pertussis has recently become a critical public health problem worldwide. To understand pertussis pathogenesis and the host response to both the pathogen and vaccines, a suitable pertussis animal model, particularly a n...

Pertussis vaccine effectiveness and duration of protection - A systematic review and me...
https://doi.org/10.1016/j.vaccine.2021.04.032
Vaccine Wilkinson K, Righolt CH et. al.

May 3rd, 2021 - A comprehensive review of observational pertussis vaccine effectiveness (VE) studies is needed to update gaps from previous reviews. We conducted a systematic review of VE and duration of protection studies for the whole-cell (wP) and acellular (a...

Characterization of a Rat Model of Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody...
https://doi.org/10.1159/000515421
Nephron Cerullo D, Rottoli D et. al.

Apr 28th, 2021 - Necrotizing crescentic glomerulonephritis (GN) associated with anti-neutrophil cytoplasmic antibodies (ANCA) against myeloperoxidase (MPO) is a devastating disease that quickly progresses to kidney failure. Current therapies are broadly immunosupp...

Bacterial RTX toxins and host immunity.
https://doi.org/10.1097/QCO.0000000000000726
Current Opinion in Infectious Diseases; Ahmad JN, Sebo P

Apr 26th, 2021 - RTX toxin action often defines the outcome of bacterial infections. Here, we discuss the progress in understanding the impacts of RTX toxin activities on host immunity. Bordetella pertussis CyaA activity paralyzes sentinel phagocytic cells by elev...

Construction and evaluation of a pertactin-deficient live attenuated pertussis vaccine ...
https://doi.org/10.1016/j.vaccine.2021.04.014
Vaccine Solans L, Debrie AS et. al.

Apr 26th, 2021 - Pertussis, mainly caused by Bordetella pertussis, is a severe respiratory disease that can be fatal, especially in young infants. Vaccines, massively implemented since the middle of the last century, have substantially reduced the pertussis incide...

see more →

News  899 results

Tdap in Pregnancy Not Tied to Childhood Adverse Outcomes
https://www.medscape.com/viewarticle/949617

Apr 20th, 2021 - (Reuters Health) - Maternal tetanus, diphtheria, and acellular pertussis (Tdap) vaccination during pregnancy isn't associated with adverse outcomes for offspring through early childhood, a new study suggests. Researchers examined data on 625,643 l...

Fast Five Quiz: DTaP and Tdap Vaccines
https://reference.medscape.com/viewarticle/943498

Jan 27th, 2021 - Vaccination series against diphtheria, tetanus, and pertussis (DTaP); tetanus, diphtheria, and pertussis (Tdap); and tetanus and diphtheria (Td) provide necessary protection against these diseases and their associated complications. It is importan...

Two Thirds of US Teens Fail to Get Needed Vaccines
https://www.staging.medscape.com/viewarticle/939695

Oct 22nd, 2020 - Only 30.6% of American adolescents complete three routinely recommended vaccinations, new research has found, but that number varies widely by state. The Advisory Committee on Immunization Practices recommends that by age 17, adolescents complete ...

Two Thirds of US Teens Fail to Get Needed Vaccines
https://www.medscape.com/viewarticle/939695

Oct 22nd, 2020 - Only 30.6% of American adolescents complete three routinely recommended vaccinations, new research has found, but that number varies widely by state. The Advisory Committee on Immunization Practices recommends that by age 17, adolescents complete ...

What to Do About Interference Between Maternal Pertussis Vaccination, Infant's DTwP Shot
https://www.medscape.com/viewarticle/935153

Aug 4th, 2020 - NEW YORK (Reuters Health) - Health providers should pay extra attention to infants with signs of pertussis given the potential interaction between maternal vaccination for the disease and the baby's responses to diphtheria, tetanus, and whole-cell...

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Patient Education  11 results see all →