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About 1,240 results

ALLMedicine™ Respiratory Syncytial Virus Infection Center

Research & Reviews  455 results

RSV-CLASS - Clinical Assessment Severity Score: An Easy-to-use Clinical Disease Severit...
https://doi.org/10.1002/jmv.28541
Journal of Medical Virology; Gsenger J, Bruckner T et. al.

Feb 3rd, 2023 - Respiratory syncytial virus (RSV) is the most common cause of acute respiratory tract infection in infants and young children often leading to severe disease requiring hospitalization. However, validated tools for systematic assessment of disease ...

Under-ascertainment of Respiratory Syncytial Virus infection in adults due to diagnosti...
https://doi.org/10.1093/infdis/jiad012
The Journal of Infectious Diseases; Onwuchekwa C, Moreo LM et. al.

Jan 21st, 2023 - Most observational population-based studies identify RSV by nasal/nasopharyngeal swab RT-PCR only. We conducted a systematic review and meta-analyses to quantify specimen and diagnostic testing-based under-ascertainment of adult RSV infection. EMB...

Incidence of Respiratory Syncytial Virus Infection in Older Adults Before and During th...
https://doi.org/10.1001/jamanetworkopen.2022.50634
JAMA Network Open; Juhn YJ, Wi CI et. al.

Jan 21st, 2023 - Little is known about the burden and outcomes of respiratory syncytial virus (RSV)-positive acute respiratory infection (ARI) in community-dwelling older adults. To assess the incidence of RSV-positive ARI before and during the COVID-19 pandemic, ...

Impact of the COVID-19 pandemic on the epidemiology of other communicable diseases in J...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837205
International Journal of Infectious Diseases : IJID : Off... Hirae K, Hoshina T et. al.

Jan 16th, 2023 - To elucidate the impact of the COVID-19 pandemic on the epidemiology of other infectious diseases. We investigated the epidemiology of 36 communicable diseases during 2015-2021 in Japan and compared the number of cases in each disease between the ...

PLZF promotes the development of asthma tolerance via affecting memory phenotypes of im...
https://doi.org/10.1016/j.intimp.2022.109559
International Immunopharmacology; Li N, Shi T et. al.

Dec 17th, 2022 - Clarifying the pathogenesis of asthma and/or identifying the specific pathway underlying oral asthma tolerance (OT) would be of great significance. In our previous study, promyelocytic leukemia zinc finger (PLZF), which reportedly regulates memory...

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Guidelines  1 results

Updated guidance for palivizumab prophylaxis among infants and young children at increa...
https://doi.org/10.1542/peds.2014-1665
Pediatrics ,

Jul 30th, 2014 - Palivizumab was licensed in June 1998 by the Food and Drug Administration for the reduction of serious lower respiratory tract infection caused by respiratory syncytial virus (RSV) in children at increased risk of severe disease. Since that time, ...

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Clinicaltrials.gov  12 results

Study to Evaluate Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection.
https://clinicaltrials.gov/ct2/show/NCT02387606

Oct 26th, 2022 - This is a randomized (study medication assigned to participants by chance), double-blind (neither physician nor participant knows the identity of the assigned treatment), placebo-controlled, single-center study of JNJ 53718678 in healthy adult par...

Study to Evaluate Safety and Antiviral Activity of Doses of JNJ-53718678 in Children (>=28 Days to <=3 Years) With Respiratory Syncytial Virus Infection
https://clinicaltrials.gov/ct2/show/NCT03656510

May 16th, 2022 - JNJ-53718678 is an investigational respiratory syncytial virus (RSV) specific fusion inhibitor and is under development for the treatment of RSV infection, which results in an upper and/or lower respiratory tract illness. The primary hypothesis of...

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults
https://clinicaltrials.gov/ct2/show/NCT04752644

Apr 1st, 2022 - A Phase 2a, Randomised, Double-Blinded, Placebo-Controlled Study to Assess the Safety, Immunogenicity and Efficacy of the Recombinant MVA-BN®-RSV Vaccine against Respiratory Syncytial Virus Infection in the Virus Challenge Model in Healthy Adult P...

An Exploratory Study to Evaluate the Prophylactic Efficacy of a Single Immunization of Ad26.RSV.preF Against Respiratory Syncytial Virus Infection in a Virus Challenge Model in Healthy 18 to 50 Yea...
https://clinicaltrials.gov/ct2/show/NCT03334695

Jul 23rd, 2021 - The purpose of this study is to assess a trend for the prophylactic efficacy of a single dose of 1*10^11 virus particles (vp) of adenovirus serotype 26 respiratory syncytial virus pre-fusion F protein (Ad26.RSV.preF) administered intramuscularly t...

A Long-term Follow-up Study to Evaluate the Impact of Lumicitabine on the Incidence of Asthma and/or Wheezing in Infants and Children With a History of Respiratory Syncytial Virus Infection
https://clinicaltrials.gov/ct2/show/NCT03332459

Apr 13th, 2021 - RSV is a leading cause of lower respiratory tract disease in infants. The primary hypothesis is that treatment of RSV-infected infants/children with lumicitabine (also known as JNJ-64041575 or ALS-008176) will decrease subsequent wheezing/asthma c...

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News  25 results

Acid Suppressants Worsen Respiratory Symptoms in Infants
https://www.staging.medscape.com/viewarticle/927518

Mar 26th, 2020 - For children exposed to acid-suppressant medications, such as proton pump inhibitors and histamine 2 receptor antagonists, during their first year of life, the risk for recurrent wheeze at age 3 is significantly elevated, researchers warn. "We are...

FUO, pneumonia often distinguishes influenza from RSV in hospitalized young children
https://www.mdedge.com/familymedicine/article/206884/pulmonary-infections/fuo-pneumonia-often-distinguishes-influenza-rsv?channel=39313
MDedge Infectious Disease; Bruce Jancin

Aug 22nd, 2019 - LJUBLJANA, SLOVENIA – Fever of unknown origin and pneumonia are two clinical features useful in distinguishing between influenza and respiratory syncytial virus infection as the cause of hospitalization in infants and young children, Cihan Papan,.

FUO, pneumonia often distinguishes influenza from RSV in hospitalized young children
https://www.mdedge.com/infectiousdisease/article/206884/pulmonary-infections/fuo-pneumonia-often-distinguishes-influenza
Bruce Jancin

Aug 22nd, 2019 - LJUBLJANA, SLOVENIA – Fever of unknown origin and pneumonia are two clinical features useful in distinguishing between influenza and respiratory syncytial virus infection as the cause of hospitalization in infants and young children, Cihan Papan,.

VIDEO: Rapid influenza test obviates empiric antivirals
https://www.mdedge.com/chestphysician/article/150645/lung-cancer/video-rapid-influenza-test-obviates-empiric-antivirals
Mitchel L. Zoler, PhD, MDedge News

Oct 31st, 2017 - TORONTO – A test that only requires a maximum 2-hour wait for results was highly accurate at detecting influenza and respiratory syncytial virus infection in lung transplant patients, according to research presented at the CHEST annual meeting on.

Is Nebulized Hypertonic Saline More Effective for Bronchiolitis?
https://www.medscape.com/viewarticle/886314

Oct 10th, 2017 - Hypertonic Versus Normal Saline Nebulizer Treatments The goal of a recent study[1] was to evaluate whether nebulized hypertonic saline (3%) was more beneficial than nebulized normal saline (0.9%) in the treatment of infants presenting to the emerg...

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Patient Education  3 results see all →