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About 221 results

ALLMedicine™ Pediatric Neuroblastoma Center

Research & Reviews  107 results

Non-inferiority of fragmented care for high-risk pediatric neuroblastoma patients: a si...
https://doi.org/10.1080/08880018.2021.1922557
Pediatric Hematology and Oncology; Tarnasky AM, Achey MA et. al.

May 10th, 2021 - Pediatric neuroblastoma (NB) patients receive multi-modal therapy and may experience care fragmented among multiple institutions with a significant travel burden, which has been associated with poor outcomes for some adult cancers. We hypothesized...

Prognostic significance of pretreatment 18F-FDG positron emission tomography/computed t...
https://doi.org/10.1007/s00247-021-05005-y 10.1016/S0140-6736(07)60983-0 10.1001/jama.2019.11642 10.1200/JCO.2008.16.6876 10.18632/oncotarget.7933 10.1200/JCO.2001.19.14.3397 10.2967/jnumed.108.060467 10.1016/j.ejrad.2015.09.027 10.1007/s13139-016-0451-8 10.2967/jnumed.110.083303 10.1097/RLU.0000000000001529
Pediatric Radiology; Sung AJ, Weiss BD et. al.

Feb 25th, 2021 - 18F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) shows tumor activity in most neuroblastomas, but the role of 18F-FDG PET/CT in neuroblastoma remains to be defined. This study explored the prognostic significance of 18F-FDG PET...

Mixed Findings in Pediatric Neuroblastoma CAR-T Therapy Trial.
https://doi.org/10.1001/jama.2020.26233
JAMA Abbasi J

Jan 12th, 2021 - Mixed Findings in Pediatric Neuroblastoma CAR-T Therapy Trial.|2021|Abbasi J,|therapy,therapeutic use,

Prognostic significance of MYCN related genes in pediatric neuroblastoma: a study based...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320557
BMC Pediatrics; Wang H, Wang X et. al.

Jun 30th, 2020 - Neuroblastoma patients with MYCN amplification are associated with poor prognosis. However, the prognostic relevance of MYCN associated genes in neuroblastoma is unclear. The expression profiles of MYCN associated genes were identified from Therap...

How well do image-defined risk factors (IDRFs) predict surgical outcomes and survival i...
https://doi.org/10.1007/s00383-020-04696-y
Pediatric Surgery International; Parhar D, Joharifard S et. al.

Jun 13th, 2020 - Since their introduction to the International Neuroblastoma Risk Group (INRG) staging system in 2009, the role of Image-Defined Risk Factors (IDRFs) in predicting outcomes has been studied in heterogeneous populations with varying results. We cond...

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Clinicaltrials.gov  111 results

Non-inferiority of fragmented care for high-risk pediatric neuroblastoma patients: a si...
https://doi.org/10.1080/08880018.2021.1922557
Pediatric Hematology and Oncology; Tarnasky AM, Achey MA et. al.

May 10th, 2021 - Pediatric neuroblastoma (NB) patients receive multi-modal therapy and may experience care fragmented among multiple institutions with a significant travel burden, which has been associated with poor outcomes for some adult cancers. We hypothesized...

Heritability Genes Identified in Childhood Neuroblastoma
https://ascopost.com/issues/may-10-2021/heritability-genes-identified-in-childhood-neuroblastoma/

May 9th, 2021 - Researchers have made progress in unravelling the genetic underpinnings of pediatric neuroblastoma. Two main inherited pathogenic genetic variants have been identified and appear to be associated with worse outcomes: the ALK gene and loss of funct...

Prognostic significance of pretreatment 18F-FDG positron emission tomography/computed t...
https://doi.org/10.1007/s00247-021-05005-y 10.1016/S0140-6736(07)60983-0 10.1001/jama.2019.11642 10.1200/JCO.2008.16.6876 10.18632/oncotarget.7933 10.1200/JCO.2001.19.14.3397 10.2967/jnumed.108.060467 10.1016/j.ejrad.2015.09.027 10.1007/s13139-016-0451-8 10.2967/jnumed.110.083303 10.1097/RLU.0000000000001529
Pediatric Radiology; Sung AJ, Weiss BD et. al.

Feb 25th, 2021 - 18F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) shows tumor activity in most neuroblastomas, but the role of 18F-FDG PET/CT in neuroblastoma remains to be defined. This study explored the prognostic significance of 18F-FDG PET...

Mixed Findings in Pediatric Neuroblastoma CAR-T Therapy Trial.
https://doi.org/10.1001/jama.2020.26233
JAMA Abbasi J

Jan 12th, 2021 - Mixed Findings in Pediatric Neuroblastoma CAR-T Therapy Trial.|2021|Abbasi J,|therapy,therapeutic use,

Prognostic significance of MYCN related genes in pediatric neuroblastoma: a study based...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320557
BMC Pediatrics; Wang H, Wang X et. al.

Jun 30th, 2020 - Neuroblastoma patients with MYCN amplification are associated with poor prognosis. However, the prognostic relevance of MYCN associated genes in neuroblastoma is unclear. The expression profiles of MYCN associated genes were identified from Therap...

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News  3 results

Tandem transplants provide EFS edge in pediatric neuroblastoma
https://www.mdedge.com/neurology/article/207309/cns/brain-cancer/tandem-transplants-provide-efs-edge-pediatric?channel=27970
Neil Osterweil

Aug 29th, 2019 - For young patients with high-risk neuroblastoma, an intensive consolidation regimen with tandem autologous stem cell transplants was associated with significantly better event-free survival, compared with single-transplant consolidation, results o.

cfDNA reveals targetable mutations in pediatric neuroblastoma, sarcoma
https://www.mdedge.com/hematology-oncology/article/166137/sarcoma-gist/cfdna-reveals-targetable-mutations-pediatric/page/0/1

May 20th, 2018 - For example, in one patient with stage 4 MYCN-amplified neuroblastoma, both tumor analysis and cfDNA revealed MYCN amplification, but cfDNA also show multiple new mutations, including a targetable NRAS mutation, secondary to clonal mutation. In 5.

ASCO 2009: Immunotherapy Prolongs Survival in High-risk Pediatric Neuroblastoma
https://www.medscape.com/viewarticle/703011

May 18th, 2009 - May 19, 2009 — An experimental immunotherapy product has been shown to improve overall survival and to reduce the risk for relapse in children with high-risk neuroblastoma. The results from a phase 3 clinical trial are due to be presented at the u...

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