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About 5,348 results

ALLMedicine™ Schistosomiasis Center

Research & Reviews  2,090 results

Endemic Thoracic Infections in Sub-Saharan Africa.
https://doi.org/10.1016/j.rcl.2022.01.003
Radiologic Clinics of North America; Rydzak CE, Lima AS et. al.

May 10th, 2022 - Although many of the thoracic infections endemic to Africa are also present around the world, this article focuses on entities that are emerging or disproportionately affect populations living in sub-Saharan Africa. Important emerging or reemergin...

Diagnosis of Schistosoma infection in non-human animal hosts: A systematic review and m...
https://doi.org/10.1371/journal.pntd.0010389
PLoS Neglected Tropical Diseases; Liang S, Ponpetch K et. al.

May 7th, 2022 - Reliable and field-applicable diagnosis of schistosome infections in non-human animals is important for surveillance, control, and verification of interruption of human schistosomiasis transmission. This study aimed to summarize uses of available ...

Morbidity indicators of urogenital schistosomosis and risk factors in school children i...
https://doi.org/10.17420/ap67801.409
Annals of Parasitology; Esiere RK, Ibeneme EO et. al.

May 3rd, 2022 - The morbidity indicators and risk factors of urinary schistosomosis in school-age children were ascertained in three Senatorial Districts of Cross River State (CRS). A cross-sectional study conducted between April 2015 and March 2016. Seven hundre...

A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B prote...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065910
EBioMedicine Perera DJ, Hassan AS et. al.

May 3rd, 2022 - Schistosomiasis is an underestimated neglected tropical disease which affects over 236.6 million people worldwide. According to the CDC, the impact of this disease is second to only malaria as the most devastating parasitic infection. Affected ind...

Comparing the accuracy of two diagnostic methods for detection of light Schistosoma hae...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053789
PloS One; Mohammed H, Landeryou T et. al.

Apr 30th, 2022 - Reagent urinalysis dipstick and filtration have been recommended diagnostic methods for the detection of urogenital schistosomiasis. However, the accurate diagnosis of light infections using these methods presents a major challenge. This study eva...

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Drugs  2 results see all →

Clinicaltrials.gov  24 results

Circulating Cathodic Antigen Test Compared to Microscopy for Diagnosis of Urinary Schistosomiasis in Sohag
https://clinicaltrials.gov/ct2/show/NCT05276414

Apr 8th, 2022 - Schistosomiasis is a chronic infection endemic in 74 tropical and sub-tropical countries. Sub-Saharan Africa carries the highest burden (90%) of schistosomiasis which caused by both Schistosoma mansoni and Schistosoma haematobium. The prevalence o...

Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults
https://clinicaltrials.gov/ct2/show/NCT03910972

Jan 20th, 2022 - The study will recruit up to 290 healthy adult males and non-pregnant females into a two-part clinical trial of a vaccine to protect against schistosomiasis caused by infection with S. mansoni. Two formulations of the Sm-TSP-2 vaccine will be test...

Single-sex Female Controlled Human Schistosomiasis Mansoni Infection
https://clinicaltrials.gov/ct2/show/NCT04269915

Aug 5th, 2021 - Groups of 3 or 7 volunteers will be exposed to a predetermined number of female Schistosoma mansoni cercariae until 10 volunteers are found infected.

A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults
https://clinicaltrials.gov/ct2/show/NCT03110757

Feb 2nd, 2021 - The study will be conducted as a randomized, controlled, double blind Phase 1b dose-escalating clinical trial in up to 60 healthy adult males and non-pregnant females living in the S. mansoni-endemic area of Americaninhas, Brazil. The study will r...

Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST)
https://clinicaltrials.gov/ct2/show/NCT02868385

Nov 18th, 2020 - An open label, randomized controlled trial of single vs. multiple treatments of praziquantel in intestinal African schistosomiasis in Côte d'Ivoire This study aims to determine the efficacy of repeated (up to four times) praziquantel treatment aga...

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News  23 results

Tropical Worm Disease Drug for Preschoolers Shown to Work in Africa Trial
https://www.medscape.com/viewarticle/963029

Nov 17th, 2021 - FRANKFURT (Reuters) - An adjusted version of an established drug against schistosomiasis, a tropical parasitic worm disease, has been shown to work in preschool children, likely offering a cure for millions, Germany's Merck KGaA said. In a late-st...

BCL-2 Emerges as an Attractive Target in Solid and Hematologic Cancers
https://www.onclive.com/view/bcl2-emerges-as-an-attractive-target-in-solid-and-hematologic-cancers

Dec 5th, 2020 - The gene encoding B-cell lymphoma-2 (BCL-2) was identified more than 30 years ago in a patient with follicular lymphoma (FL) who had a chromosomal translocation that led to dysregulated BCL-2 expression.1 When the BCL-2 gene product was reported t...

What Neglected Tropical Diseases Teach Us About Stigma
https://www.mdedge.com/dermatology/article/209336/infectious-diseases/what-neglected-tropical-diseases-teach-us-about?channel=234
Aileen Y. Chang, MD, Maria T. Ochoa, MD

Oct 3rd, 2019 - Neglected tropical diseases (NTDs) are a group of 20 diseases that typically are chronic and cause long-term disability, which negatively impacts work productivity, child survival, and school performance and attendance with adverse effect on futur.

Ebola in the DRC: Will New Tx Bring Hope in the New Year?
https://www.medpagetoday.com/infectiousdisease/ebola/77286

Jan 7th, 2019 - The latest Ebola outbreak in the Democratic Republic of the Congo continues to rage on, with no end in sight. In this exclusive MedPage Today video, two infectious disease experts -- Peter Hotez, MD, of Baylor College of Medicine in Houston and An...

Gene study reveals secrets of parasitic worms, possible treatments
https://www.reuters.com/article/us-health-worms/gene-study-reveals-secrets-of-parasitic-worms-possible-treatments-idUSKCN1NA21V

Nov 5th, 2018 - LONDON (Reuters) - The largest study to date of the genetic makeup of parasitic worms has found hundreds of new clues about how they invade the human body, evade its immune system and cause disease. FILE PHOTO: A giant 25m worm representing the pa...

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