ALLMedicine™ Asthma Center

Jul 31st, 2021 - Cockroach allergen is one of the most important asthma triggers for children. There is an extensive body of research on interventions to reduce exposure. However, adherence to these interventions is low. Insight into the knowledge, attitudes, and ...

Jul 31st, 2021 - Asthma is a heterogeneous syndrome substantiating the urgent requirement for endotype-specific biomarkers. Dysbalance of fibrosis and fibrolysis in asthmatic lung tissue leads to reduced levels of the inflammation-protective collagen 4 (COL4A3). T...

Jul 31st, 2021 - Researchers use different definitions to identify children with asthma in epidemiological surveys. We conducted a systematic review to describe the definitions used in epidemiologic studies for wheeze and asthma in the paediatric population, aimed...

Jul 31st, 2021 - Omalizumab is an anti-IgE monoclonal antibody used in severe allergic asthma. Herein, we describe a case of eosinophilic granulomatosis with polyangiitis, which manifested 3 months after initiation of omalizumab therapy, while maintenance corticos...

Jul 31st, 2021 - Asthma is characterized by recurrent episodes of wheezing, dyspnea, chest tightness and cough. In addition to respiratory symptoms, previous studies have reported the presence of pain. To analyse the nociceptive processing of young adults with wel...

Dec 4th, 2020 - Asthma is a major public health problem worldwide and is associated with excess morbidity, mortality, and economic costs associated with lost productivity. The National Asthma Education and Prevention Program has released the 2020 Asthma Guideline...

Aug 4th, 2020 - In 2017, the Addendum Guidelines for the Prevention of Peanut Allergy were published with recommendations on early introduction of peanut-containing foods based on infants' clinical history. We sought to conduct a nationwide US survey to assess Gu...

Jul 30th, 2020 - We developed evidence-based recommendations for prehospital evaluation and treatment of adult patients with respiratory distress. These recommendations are compared with current protocols used by the 33 local emergency medical services agencies (L...

Jun 6th, 2020 - The outbreak of the SARS-CoV-2-induced coronavirus disease 2019 (COVID-19) pandemic re-shaped doctor-patient interaction and challenged capacities of healthcare systems. It created many issues around the optimal and safest way to treat complex pat...

Jan 24th, 2020 - Asthma and non-asthmatic eosinophilic bronchitis (NAEB) are among the commonest causes of chronic cough in adults. We sought to determine the role of non-invasive measurements of airway inflammation, including induced sputum and fractional exhaled...

May 8th, 2020 - Subjects who have not met investigational product discontinuation criteria and have attended the EOT visit in either study D5180C00007 or D5180C00009 will be offered the opportunity to consent for the Multicentre, Double-blind, Randomized, Paralle...

May 6th, 2020 - Prevention/ Disease modification of asthma.

May 6th, 2020 - A Phase 3b Proof-of-Concept study to evaluate the ability of fevipiprant dose 1 and dose 2, compared with placebo, as add-on to nasal spray standard-of-care (SoC), in reducing endoscopic nasal polyp score in adult (≥ 18 years) patients with nasal ...

May 5th, 2020 - Objective: The aim of the study was to evaluate the validity and reliability of the six-minute pegboard and ring test in patients with controlled and partially controlled asthma. Demographic information: Name, age, diagnosis, occupation, body weig...

May 4th, 2020 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

Jul 15th, 2021 - Benralizumab (Fasenra) significantly reduced nasal polyp score (NPS) and average nasal blockage score (NBS) compared with placebo for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) in a phase 3 trial. The randomized, multic...

Jul 14th, 2021 - The US Food and Drug Administration (FDA) has granted priority review for the biologic tezepelumab (AstraZeneca/Amgen) for treatment of severe asthma. The announcement was reported July 8, just days before the start of the European Academy of Alle...

Jul 11th, 2021 - About one third of asthma patients have high use of short-acting beta agonists (SABAs) in Europe across all severity levels, said Santiago Quirce, MD, PhD, with Hospital Universitario in Madrid, Spain. High use — defined as three or more canisters...

Jul 10th, 2021 - Dupilumab (Dupixent, Sanofi and Regeneron) significantly reduced exacerbations compared with placebo in children ages 6-11 years who had moderate-to-severe asthma in a phase 3 trial. A fully human monoclonal antibody, dupilumab also improved lung ...

Jul 7th, 2021 - Asthma is a common, chronic inflammatory disorder of the airways characterized by shortness of breath, wheezing, coughing, chest tightness, variable airflow limitation, and tissue remodeling. Nearly 400 million people around the world have asthma,...