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About 48,646 results

ALLMedicine™ Cystic Fibrosis Center

Research & Reviews  23,407 results

PROMISE: Working with the CF community to understand emerging clinical and research nee...
https://doi.org/10.1016/j.jcf.2021.02.003
Journal of Cystic Fibrosis : Official Journal of the Euro... Nichols DP, Donaldson SH et. al.

Feb 23rd, 2021 - Highly effective CFTR modulator drug therapy is increasingly available to those with cystic fibrosis. Multiple observational research studies are now being conducted to better understand the impacts of this important therapeutic milestone on long-...

Withdrawal of dornase alfa increases ventilation inhomogeneity in children with cystic ...
https://doi.org/10.1016/j.jcf.2021.02.004
Journal of Cystic Fibrosis : Official Journal of the Euro... Voldby C, Green K et. al.

Feb 23rd, 2021 - The lung clearance index (LCI) is increasingly used as an outcome in clinical trials of patients with mild cystic fibrosis (CF) lung disease. Yet, understanding the impact of standard CF respiratory therapy on LCI is needed. We assessed to what de...

An evaluation of healthcare utilization and clinical charges in children and adults wit...
https://doi.org/10.1002/ppul.25251
Pediatric Pulmonology; Perkins RC, Shah M et. al.

Feb 23rd, 2021 - Prior studies have estimated healthcare costs for cystic fibrosis (CF) of $8000-$131,000, but do not account for impacts of CF modulator therapy. This study aims to assess utilization patterns and cost of CF care in a center in the United States. ...

Outcomes of cystic fibrosis pulmonary exacerbations treated with antibiotics with activ...
https://doi.org/10.1016/j.jcf.2021.02.001
Journal of Cystic Fibrosis : Official Journal of the Euro... Castner LM, Zimbric M et. al.

Feb 22nd, 2021 - Obligate and facultative anaerobic bacteria are prevalent in cystic fibrosis (CF) airways. Increases in anaerobe relative abundance have been associated with CF pulmonary exacerbations (PEx); however, the impact of antibiotic treatment of anaerobe...

Novel Correctors and Potentiators Enhance Functional Rescue of CFTR Nonsense Mutation T...
https://doi.org/10.1165/rcmb.2019-0291OC
American Journal of Respiratory Cell and Molecular Biology; Mutyam V, Sharma J et. al.

Feb 22nd, 2021 - Premature termination codons (PTCs) in cystic fibrosis transmembrane conductance regulator (CFTR) result in nonfunctional CFTR protein and are the proximate cause of ~11% of CF-causing alleles for which no treatments exist. CFTR corrector, lumacaf...

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Guidelines  85 results

Academy of Nutrition and Dietetics: 2020 Cystic Fibrosis Evidence Analysis Center Evide...
https://doi.org/10.1016/j.jand.2020.03.015
Journal of the Academy of Nutrition and Dietetics; McDonald CM, Alvarez JA et. al.

Jun 17th, 2020 - The Academy of Nutrition and Dietetics Evidence Analysis Center conducted a systematic review of the literature to develop an evidence-based practice guideline for primary nutrition issues in cystic fibrosis (CF). This guideline is designed to com...

Direct-to-consumer genetic testing
https://www.ama-assn.org/delivering-care/precision-medicine/direct-consumer-genetic-testing

Apr 2nd, 2019 - Types of DTC genetic tests A broad range of genetic test types are offered DTC, including: Carrier testing for diseases such as cystic fibrosis and hemochromatosis Pharmacogenomic testing Testing for predisposition to complex diseases such as her...

Practice Advisory: Cell-free DNA to Screen for Single-Gene Disorders
https://www.acog.org/Clinical-Guidance-and-Publications/Practice-Advisories/Cell-free-DNA-to-Screen-for-Single-Gene-Disorders

Feb 20th, 2019 - The continued innovation in cell-free technology combined with the desire for a maternal blood test to predict the risk for fetal genetic disorders during a pregnancy has broadened the application of cell-free DNA screening beyond aneuploidy to si...

Home Oxygen Therapy for Children. An Official American Thoracic Society Clinical Practice Guideline
https://www.atsjournals.org/doi/full/10.1164/rccm.201812-2276ST
Hayes,D.,et al

Jan 31st, 2019 - Although home oxygen therapy is commonly required in the care of children, there is a striking lack of empirical evidence regarding implementation, monitoring, and discontinuation of supplemental oxygen therapy. The panel formulated and provided t...

Nutritional Considerations in Pediatric Pancreatitis: A Position Paper from the NASPGHA...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020697
Journal of Pediatric Gastroenterology and Nutrition; Abu-El-Haija M, Uc A et. al.

Jun 21st, 2018 - Wide variations exist in how physicians manage the nutritional aspects of children affected by acute pancreatitis (AP), acute recurrent pancreatitis (ARP), and chronic (CP) pancreatitis. Better consensus for optimal management is needed. This cons...

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Drugs  95 results see all →

Clinicaltrials.gov  24,203 results

PROMISE: Working with the CF community to understand emerging clinical and research nee...
https://doi.org/10.1016/j.jcf.2021.02.003
Journal of Cystic Fibrosis : Official Journal of the Euro... Nichols DP, Donaldson SH et. al.

Feb 23rd, 2021 - Highly effective CFTR modulator drug therapy is increasingly available to those with cystic fibrosis. Multiple observational research studies are now being conducted to better understand the impacts of this important therapeutic milestone on long-...

Withdrawal of dornase alfa increases ventilation inhomogeneity in children with cystic ...
https://doi.org/10.1016/j.jcf.2021.02.004
Journal of Cystic Fibrosis : Official Journal of the Euro... Voldby C, Green K et. al.

Feb 23rd, 2021 - The lung clearance index (LCI) is increasingly used as an outcome in clinical trials of patients with mild cystic fibrosis (CF) lung disease. Yet, understanding the impact of standard CF respiratory therapy on LCI is needed. We assessed to what de...

An evaluation of healthcare utilization and clinical charges in children and adults wit...
https://doi.org/10.1002/ppul.25251
Pediatric Pulmonology; Perkins RC, Shah M et. al.

Feb 23rd, 2021 - Prior studies have estimated healthcare costs for cystic fibrosis (CF) of $8000-$131,000, but do not account for impacts of CF modulator therapy. This study aims to assess utilization patterns and cost of CF care in a center in the United States. ...

Outcomes of cystic fibrosis pulmonary exacerbations treated with antibiotics with activ...
https://doi.org/10.1016/j.jcf.2021.02.001
Journal of Cystic Fibrosis : Official Journal of the Euro... Castner LM, Zimbric M et. al.

Feb 22nd, 2021 - Obligate and facultative anaerobic bacteria are prevalent in cystic fibrosis (CF) airways. Increases in anaerobe relative abundance have been associated with CF pulmonary exacerbations (PEx); however, the impact of antibiotic treatment of anaerobe...

Novel Correctors and Potentiators Enhance Functional Rescue of CFTR Nonsense Mutation T...
https://doi.org/10.1165/rcmb.2019-0291OC
American Journal of Respiratory Cell and Molecular Biology; Mutyam V, Sharma J et. al.

Feb 22nd, 2021 - Premature termination codons (PTCs) in cystic fibrosis transmembrane conductance regulator (CFTR) result in nonfunctional CFTR protein and are the proximate cause of ~11% of CF-causing alleles for which no treatments exist. CFTR corrector, lumacaf...

see more →

News  813 results

Fast Five Quiz: Spinal Muscular Atrophy Clinical Presentation
https://reference.medscape.com/viewarticle/944574

Jan 31st, 2021 - Spinal muscular atrophy (SMA) consists of a group of autosomal-recessive disorders characterized by progressive weakness of the lower motor neurons. Estimates suggest 1 in 6000 to 1 in 10,000 individuals are affected, making SMA the second most co...

Telehealth Finds Acceptance Among Patients With Cf, Clinicians
https://www.medscape.com/viewarticle/941411

Nov 22nd, 2020 - Telehealth is widely accepted among individuals with cystic fibrosis (CF) and the physicians who treat them, according to three new studies. The surveys examined attitudes during the COVID-19 pandemic, which complicates interpretation of the surve...

Cystic Fibrosis Patients' Vulnerability to COVID-19 Infection: Preliminary Data Ease Fears
https://www.medscape.com/viewarticle/940797

Nov 10th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Clinicians treating patients with cystic fibrosis (CF) have had to face the possibility that their patients may be particularly susceptible to SAR...

Home Spirometry Improved Monitoring of Cystic Fibrosis Patients During COVID-19 Pandemic
https://www.staging.medscape.com/viewarticle/940517

Nov 5th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Home spirometry has become increasingly used among cystic fibrosis patients during the COVID-19 pandemic, and new research suggests that home devi...

Home Spirometry Improved Monitoring of Cystic Fibrosis Patients During COVID-19 Pandemic
https://www.medscape.com/viewarticle/940517

Nov 5th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Home spirometry has become increasingly used among cystic fibrosis patients during the COVID-19 pandemic, and new research suggests that home devi...

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Patient Education  43 results see all →