About 1,558 results
Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations.
Gastroenterology Hadjiliadis D, Khoruts A et. al.

Dec 31st, 2017 - Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5-10 times greater compared to the general population, and 25-30 times greater in CF patients after an organ transplantation. To address this risk, the CF Foundation convened a multi-stakeholder task force to develop CRC screening recommendatio...

New Clinical Trial Aims to Reduce Malnutrition Among Patients with Lung Cancer
Cancer Network; Slater H

Nov 17th, 2019 - The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), along with Tufts Medical Center, Fox Chase Cancer Center, and MD Anderson Cancer Center, announced a new clinical trial aiming to reduce malnutrition among patients with lung cancer by offering nutritional counseling and medically tailored meals to patie...

High-protein Diet is Bad for Kidney Health: Unleashing the Taboo
Nephrology Dialysis Transplantation; Kalantar-Zadeh K, et al

Nov 6th, 2019 - How often have you been told to eat more protein and less carbohydrates to stay healthy? This is not an emerging food culture but rather a prevailing dogma in our society. Physicians, dietitians and other health care professionals tell us constantly about the advantages of a high-protein diet (HPD), such as losing weight rapidly, burning calories, diminishing appetite, preventing obesity, manag...

Shingles - Genetics Home Reference - NIH

Oct 28th, 2019 - Shingles (also known as herpes zoster) results from infection by the varicella zoster virus. This common virus causes chickenpox (also known as varicella), which is characterized by itchy spots on the skin that cover the whole body and usually occurs in childhood or adolescence. After the body fights the initial infection, the varicella zoster virus remains in nerve cells for the rest of a per...

Pediatric Metabolic and Bariatric Surgery: Evidence, Barriers, and Best Practices
Pediatrics Armstrong, S. et. al.

Oct 27th, 2019 - Severe obesity among youth is an “epidemic within an epidemic” and portends a shortened life expectancy for today’s children compared with those of their parents’ generation. Severe obesity has outpaced less severe forms of childhood obesity in prevalence, and it disproportionately affects adolescents. Emerging evidence has linked severe obesity to the development and progression of multiple co...

Asthma in Adults
Medical Clinics of North America; Nanda A, et al

Oct 27th, 2019 - Asthma affects approximately 300 million people worldwide and approximately 7.5% of adults in the United States. Among adults, asthma results in about 10.5 million physician office visits per year and affects approximately 8.7% of blacks, 7.6% of whites, and 5.8% of Hispanics. Asthma is characterized by inflammation of airways, variable airflow obstruction, and bronchial hyperresponsiveness.3 I...

Genentech Announces FDA Approval of Xofluza (Baloxavir Marboxil) for People at High Risk of Developing Influenza-Related Complications

Oct 16th, 2019 - Single-dose Xofluza is the first and only antiviral medicine indicated specifically for patients at high risk of developing serious complications from influenza (flu) The Centers for Disease Control and Prevention (CDC) defines people at high risk of serious flu complications as those who have conditions such as asthma, chronic lung disease, diabetes, heart disease, morbid obesity or adults ...

Weight change across adulthood in relation to all cause and cause specific mortality: prospective cohort study
BMJ Chen, C. et. al.

Oct 15th, 2019 - Objective To investigate the association between weight changes across adulthood and mortality. Design Prospective cohort study. Setting US National Health and Nutrition Examination Survey (NHANES) 1988-94 and 1999-2014. Participants 36 051 people aged 40 years or over with measured body weight and height at baseline and recalled weight at young adulthood (25 years old) and middle adul...

Association of Cardiovascular Disease With Premature Mortality in the United States
JAMA Cardiology; Chen, Y. et. al.

Oct 15th, 2019 - Question How have the trends in premature mortality from cardiovascular disease (CVD) changed in the United States during 2000 to 2015 by demographics and county-level factors, including education, rurality, and the prevalence of smoking, obesity, and diabetes? Findings In this study, CVD mortality rates increased significantly among American Indian/Alaska Native individuals age 25 to 49 y...

National Update on Measles Cases and Outbreaks — United States, January 1–October 1, 2019
Morbidity and Mortality Weekly Report; Patel, M. et. al.

Oct 3rd, 2019 - What is already known about this topic? Measles was eliminated in the United States in 2000. High national coverage with measles, mumps, and rubella vaccine and rapid implementation of measles control measures prevent widespread measles transmission. What is added by this report? During January–September 2019, 1,249 U.S. measles cases were reported, the highest annual number since 1992...

Preventive Cardiology as a Subspecialty of Cardiovascular Medicine
Journal of the American College of Cardiology; Shapiro, M. et. al.

Oct 1st, 2019 - Although significant progress has been made to reduce the global burden of cardiovascular disease, efforts have focused primarily on treatment of manifest disease rather than on prevention of events. An enormous opportunity exists to transition focus from intervention to providing equal attention to prevention of cardiovascular disease. The nascent specialty of “preventive cardiology” is emergi...

Hand-Foot-and-Mouth Disease: Rapid Evidence Review
American Family Physician; Saguil, A. et. al.

Sep 30th, 2019 - Hand-foot-and-mouth disease is caused by human enteroviruses and coxsackieviruses. Outbreaks can occur in the spring to fall and are common in North America, and most cases occur in patients younger than 10 years. Hand-foot-and-mouth disease is transmitted by fecal-oral, oral-oral, and respiratory droplet contact. Patients present with a low-grade fever, a maculopapular or papulovesicular rash ...

Global Initiative for Asthma: Global Strategy for Asthma Management & Prevention

Sep 29th, 2019 - The 2019 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel of experts on the GINA Science Committee. This comprehensive and practical resource about one of the most common chronic lung diseases worldwide contains extensive citations from the scientifi...

Can Mild Asthma Be Managed with Only As-Needed Inhaled Steroids Plus a Bronchodilator?

Sep 25th, 2019 - David J. Amrol, MD reviewing Hardy J et al. Lancet 2019 Sep 14 Gauthier M and Wenzel SE. Lancet 2019 Sep 14

Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study

Sep 15th, 2019 - BACKGROUND: Donepezil, rivastigmine and galantamine are popular cholinesterase inhibitors used to manage the symptoms of Alzheimer disease and other dementias; regulatory agencies in several countries warn about a possible risk of rhabdomyolysis with donepezil, based on information from case reports. Our goal was to investigate the 30-day risk of admission to hospital with rhabdomyolysis associ...

Nucala is the first biologic approved in the US for six to 11-year-old children with severe eosinophilic asthma

Sep 11th, 2019 - GlaxoSmithKline (LSE/NYSE: GSK) today announced that the US Food and Drug Administration (FDA) has approved Nucala (mepolizumab) for use in children as young as six years old who are living with severe eosinophilic asthma. Nucala is the only targeted biologic to be approved for the condition in the six to 11-year age group in the US.

New CDC Obesity Prevalence Maps: Nine states report adult obesity at or above 35 percent

Sep 11th, 2019 - In 2018, nine states reported an adult obesity prevalence at or above 35 percent: Alabama, Arkansas, Iowa, Kentucky, Louisiana, Mississippi, Missouri, North Dakota, and West Virginia. This comes from the new obesity prevalence maps released today by the Centers for Disease Control and Prevention.

Laparoscopic management of a migrated intragastric balloon causing mechanical small bowel obstruction: a case report and review of the literature
Annals of The Royal College of Surgeons of England; Hay D, et al

Sep 5th, 2019 - Intragastric balloons have been used as an invasive non-surgical treatment for obesity for over 30 years. Within the last 37 years, we have found only 27 cases reported in the literature of intestinal obstruction caused by a migrated intragastric balloon. We report the laparoscopic management of such a case and make observations from similar case presentations published in the literature. A ...

County of Rockland, New York :: Measles Information

Aug 25th, 2019 - 2018 - 2019 Measles Outbreak in Rockland County: As of August 26, 2019, there are 312* confirmed reported cases of measles in Rockland County. *On Monday, August 26, 2019, 16 historical cases of measles were added to the current total. These cases occurred between early February 2019 and mid-May 2019.

FDA warns consumers about the dangerous and potentially life threating side effects of Miracle Mineral Solution

Aug 11th, 2019 - The U.S. Food and Drug Administration is warning consumers not to purchase or drink a product sold online as a medical treatment due to a recent rise in reported health issues. Since 2010, the FDA has warnedExternal Link Disclaimer consumers about the dangers of Miracle or Master Mineral Solution, Miracle Mineral Supplement, MMS, Chlorine Dioxide (CD) Protocol, Water Purification Solution (WPS)...

The Family Physician’s Role in the Prevention of Measles
American Family Physician;

Jul 28th, 2019 - Measles is one of the most highly transmissible diseases, with 90% of unvaccinated persons infected after contact.1 In 2000, the Centers for Disease Control and Prevention (CDC) declared that measles was eliminated in the United States, but that elimination status may be revoked if the current chain of measles transmission and outbreaks continues for one year, through the fall of 2019. As ...

City of El Paso- Measles Information

Jul 17th, 2019 - Measles is one of the most easily transmitted viruses known to man. It spreads via the respiratory system – much like influenza and TB. An infected person coughs the virus and others inhale it. The measles virus remains infectious in the air up to two hours after the infectious individual has left the area.

FDA Approves Merck’s RECARBRIO™ (imipenem, cilastatin, and relebactam) For the Treatment of Adults with Complicated Urinary Tract and Complicated Intra-Abdominal Bacterial Infections Where Limited ...

Jul 16th, 2019 - Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved RECARBRIO™ (imipenem, cilastatin, and relebactam) for injection, 1.25 grams, a new combination antibacterial. RECARBRIO is indicated in patients 18 years of age and older who have limited or no alternative treatment options, for the treatment of comp...

Risk of Acute Myocardial Infarction and Ischemic Stroke in Patients with Asthma Exacerbation: A Population-Based, Self-Controlled Case Series Study
The Journal of Allergy and Clinical Immunology: In Practice; Raita, Y. et. al.

Jul 15th, 2019 - Background Patients with asthma have a high incidence of acute myocardial infarction and ischemic stroke. Objective To investigate the acute effect of asthma exacerbation on these cardiovascular events. Methods Using population-based inpatient data of 3 geographically diverse US states (Florida, Nebraska, and New York) during the period 2011 to 2014, we conducted a self-controlled case...

Polycystic kidney disease

Jul 15th, 2019 - Polycystic kidney disease is a disorder that affects the kidneys and other organs. Clusters of fluid-filled sacs, called cysts, develop in the kidneys and interfere with their ability to filter waste products from the blood. The growth of cysts causes the kidneys to become enlarged and can lead to kidney failure. Cysts may also develop in other organs, particularly the liver.

Teva Announces FDA Approval of AirDuo® Digihaler™ (fluticasone propionate 113 mcg and salmeterol 14 mcg) Inhalation Powder

Jul 14th, 2019 - Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA) announced today that the U.S. Food and Drug Administration (FDA) has approved AirDuo® Digihaler™ (fluticasone propionate 113 mcg and salmeterol 14 mcg) Inhalation Powder, a combination therapy digital inhaler with built-in sensors that connects to a companion mobile application to provide information on inhaler use to people with asthma....

Obesity Among HIV-Infected Adults Receiving Medical Care in the United States: Data From the Cross-Sectional Medical Monitoring Project and National Health and Nutrition Examination Survey

Jul 12th, 2019 - Our objective was to compare obesity prevalence among human immunodeficiency virus (HIV)-infected adults receiving care and the U.S. general population and identify obesity correlates among HIV-infected men and women. Cross-sectional data was collected in 2009 to 2010 from 2 nationally representative surveys: Medical Monitoring Project (MMP) and National Health and Nutrition Examination Surv...

NIH Fact Sheets - Autosomal Dominant Polycystic Kidney Disease

Jun 29th, 2019 - Autosomal Dominant Polycystic Kidney Disease (ADPKD) resulted in end-stage renal disease (ESRD) by age 53, on average, and was responsible for 6 percent of ESRD cases in the U.S.

Clinical Trials | NUCALA (mepolizumab)

Jun 26th, 2019 - NUCALA (mepolizumab) has clinical data on exacerbation reduction. Learn about NUCALA for patients with severe eosinophilic asthma.

Atopic dermatitis/Eczema | DermNet NZ

Jun 24th, 2019 - Atopic dermatitis is a chronic, itchy skin condition that is very common in children but may occur at any age. It is also known as eczema and atopic eczema and was formerly known as Besnier prurigo. It is the most common form of dermatitis. Atopic dermatitis usually occurs in people who have an 'atopic tendency'. This means they may develop any or all of three closely linked conditions; atop...

U.S. measles cases in first five months of 2019 surpass total cases per year for past 25 years

May 29th, 2019 - Today, CDC is reporting 971 cases of measles in the United States thus far in 2019. This is the greatest number of cases reported in the U.S. since 1994, when 963 cases were reported for the entire year. CDC continues to work with affected state and local health departments to get ongoing outbreaks under control.

Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease
The Cochrane Database of Systematic Reviews; Threapleton, C. et. al.

May 23rd, 2019 - Chronic obstructive pulmonary disease (COPD; including chronic bronchitis and emphysema) is a chronic respiratory condition characterised by shortness of breath, cough and recurrent exacerbations. Long‐term antibiotic use may reduce both bacterial load and inflammation in the airways. Studies have shown a reduction of exacerbations with antibiotics in comparison to placebo in people with COPD, ...

Preventable Cancer Burden Associated with Poor Diet in the United States
Cancer Spectrum; Zhang, F. et. al.

May 21st, 2019 - Diet is an important risk factor for cancer that is amenable to intervention. Estimating the cancer burden associated with diet informs evidence-based priorities for nutrition policies to reduce cancer burden in the US. Methods Using a Comparative Risk Assessment model that incorporated nationally representative data on dietary intake, national cancer incidence, and estimated associations o...

Rate of life-threatening childbirth complications increasing sharply across U.S. racial, ethnic groups

May 2nd, 2019 - Racial and ethnic disparities in severe maternal morbidity — life-threatening maternal complications associated with childbirth — have persisted and increased at high rates among U.S. women, according to an analysis of nearly 20 years of California hospital records funded by the National Institutes of Health. Known risk factors for these complications — such as blood pressure disorders, asthma ...

Practice Advisory: Management of Pregnant and Reproductive-Aged Women during a Measles Outbreak

Apr 25th, 2019 - The United States is currently experiencing the greatest number of reported cases of measles, also known as rubeola, since the disease was eliminated in 20001. Outbreaks have been confirmed in 22 states and the number of cases and their distribution is increasing rapidly. These measles outbreaks have been linked to travelers bringing back cases of measles from other countries. This situation co...

BAROnova Announces FDA Approval of the TransPyloric Shuttle® (TPS®) Device

Apr 22nd, 2019 - BAROnova, Inc., a medical device company focused on the development of first-in-class non-surgical solutions for the treatment of obesity, announced today that the U.S. Food and Drug Administration (FDA) has approved the TransPyloric Shuttle® (TPS®) Device, a non-surgical weight loss solution for adult individuals suffering from obesity with a body mass index (BMI) of 30 to 40 kg/m2. The device...

Measles & the MMR Vaccine: Recommendations Around Pregnancy, Including the Periconception and Postpartum Periods

Apr 14th, 2019 - Measles, Also Known As Rubeola, Is A Highly Contagious Airborne Viral Illness That Infects Approximately Nine Out Of Ten Exposed Susceptible Individuals. Measles Infection Was Common Until The Measles, Mumps, And Rubella (MMR) Vaccine Was Licensed In 1963 And Became Part Of The Routine Immunization Schedule. By 2000, Measles Was Essentially Eliminated From The United States. In The Last Decade,...

Gelesis Granted FDA Clearance to Market PLENITY™ — a New Prescription Aid in Weight Management

Apr 13th, 2019 - Gelesis, a biotechnology company developing first-in-class hydrogel therapeutics to treat obesity and other chronic diseases related to the gastrointestinal (GI) tract, today announced that the United States Food and Drug Administration (FDA) has cleared the Company’s lead product candidate, PLENITY™ (Gelesis100), as an aid in weight management in adults with a Body Mass Index (BMI) of 25–40 k...

Direct-to-consumer genetic testing

Apr 2nd, 2019 - Types of DTC genetic tests A broad range of genetic test types are offered DTC, including: Carrier testing for diseases such as cystic fibrosis and hemochromatosis Pharmacogenomic testing Testing for predisposition to complex diseases such as hereditary cancers, cardiovascular disease and depression Whole exome or genome sequencing Testing to determine ancestry

Measles Cases and Outbreaks

Mar 31st, 2019 - Measles Cases in 2019 From January 1 to February 21, 2019, 159** individual cases of measles have been confirmed in 10 states. In a given year, more measles cases can occur for any of the following reasons: an increase in the number of travelers who get measles abroad and bring it into the U.S., and/or further spread of measles in U.S. communities with pockets of unvaccinated people.

World Autism Awareness Day 2 April

Mar 31st, 2019 - On World Autism Awareness Day, we speak out against discrimination, celebrate the diversity of our global community and strengthen our commitment to the full inclusion and participation of people with autism. Supporting them to achieve their full potential is a vital part of our efforts to uphold the core promise of the 2030 Agenda for Sustainable Development: to leave no one behind

Autism Spectrum Disorder (ASD) | Autism | NCBDDD | CDC

Mar 31st, 2019 - Autism Spectrum Disorder (ASD) is a developmental disability that can cause significant social, communication and behavioral challenges. CDC is working to find out how many children have ASD, discover the risk factors, and raise awareness of the signs.

Guidelines Insights: Hepatobiliary Cancers, Version 2.2019
Benson, A. et. al.

Mar 31st, 2019 - Incidence and mortality rates for cancer overall are declining, but both incidence and mortality rates for hepatocellular carcinoma (HCC) are increasing.1,2 Risk factors for development of HCC include infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV), and cirrhosis of the liver (eg, alcohol cirrhosis).3 Metabolic disorders (ie, obesity, diabetes, impaired glucose metabolism,...

The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation
Biomedicines Jones L, et al

Mar 27th, 2019 - The gut microbiota is extremely important for the health of the host across its lifespan.Recent studies have elucidated connections between the gut microbiota and neurological diseaseand disorders such as depression, anxiety, Alzheimer's disease (AD), autism, and a host of otherbrain illnesses. Dysbiosis of the normal gut flora can have negative consequences for humans,especially throughout key...

Asthma Data, Statistics, and Surveillance

Mar 24th, 2019 - The latest national and state data on the burden of asthma among children and adults.

AMSSM position statement update: blood-borne pathogens in the context of sports participation
McGrew, C.,et al

Mar 18th, 2019 - This American Medical Society for Sports Medicine position statement update is directed towards healthcare providers of patients involved in sport and exercise. There have been significant advances in clinical and scientific research in the understanding of blood-borne pathogens (BBPs), and this update incorporates these advancements.

The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing...

Mar 17th, 2019 - This clinical report updates and replaces a 2008 clinical report from the American Academy of Pediatrics, which addressed the roles of maternal and early infant diet on the prevention of atopic disease, including atopic dermatitis, asthma, and food allergy. As with the previous report, the available data still limit the ability to draw firm conclusions about various aspects of atopy prevention ...

Mumps | For Healthcare Providers | CDC

Mar 14th, 2019 - Mumps is a viral illness caused by a paramyxovirus, a member of the Rubulavirus family. The average incubation period for mumps is 16 to 18 days, with a range of 12 to 25 days.

AAP Updates Vaccine Recommendations for 2019-2020 Flu Season

Mar 13th, 2019 - The American Academy of Pediatrics (AAP) will advise families to vaccinate their children against influenza next season with either the flu shot or the nasal spray vaccine for the best protection against the virus during the 2019-2020 flu season. The recommendation differs slightly from last year, when AAP cited a preference for the injected vaccine over the nasal spray - except in cases whe...

Genomic Survey of Bordetella pertussis Diversity, United States, 2000–2013
Emerging Infectious Diseases; Weigand, M. et. al.

Mar 12th, 2019 - We characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurring amid the current pertussis disease resurgence and provide a foundation for needed research to direct future public health control strategies.

Pancreatic Adenocarcinoma, Version 1.2019
Journal of the National Comprehensive Cancer Network; Tempero, M. et. al.

Mar 9th, 2019 - In 2019, an estimated 56,770 people in the United States will be diagnosed with pancreatic cancer and approximately 45,750 will die of the disease.1 Pancreatic cancer is the fourth most common cause of cancer-related death among US men (after lung, prostate, and colorectal cancers) and women (after lung, breast, and colorectal cancers).1 From 1999 to 2008, the incidence of pancreatic cancer inc...

Measles - StatPearls

Mar 5th, 2019 - Measles, also known as rubeola, is a preventable, highly contagious, acute febrile viral illness. It remains an important cause of global mortality and morbidity, particularly in the regions of Africa and Southeast Asia

Adhansia XR Approved for the Treatment of Pediatric, Adult ADHD

Feb 28th, 2019 - The Food and Drug Administration (FDA) has approved Adhansia XR (methylphenidate HCl extended-release; Adlon Therapeutics), a central nervous system stimulant, for the treatment of attention deficit hyperactivity disorder (ADHD) in patients 6 years and older. The approval of Adhansia XR was based on data from 4 clinical trials evaluating the safety and efficacy of the treatment in adult and ...

Vaccine Storage and Handling

Feb 27th, 2019 - Proper vaccine storage and handling practices play a very important role in protecting individuals and communities from vaccine-preventable diseases.Vaccine quality is the shared responsibility of everyone, from the time vaccine is manufactured until it is administered.

Asthma More Common in Opioid-Dependent Patients
Boyles, S.

Feb 23rd, 2019 - The prevalence of asthma was nearly twice as high as the national average in a cohort of opioid-dependent patients receiving acute care at an inner city hospital in a New York City borough, with female sex more closely linked to higher asthma risk than male sex, researchers reported here.

Coverage from the American Academy of Allergy, Asthma and Immunology (AAAAI) 2019 Meeting

Feb 21st, 2019 - American Academy of Allergy, Asthma and Immunology (AAAAI) 2019 Meeting: Read clinically focused news coverage of key developments from AAAAI 2019

Practice Advisory: Cell-free DNA to Screen for Single-Gene Disorders

Feb 20th, 2019 - The continued innovation in cell-free technology combined with the desire for a maternal blood test to predict the risk for fetal genetic disorders during a pregnancy has broadened the application of cell-free DNA screening beyond aneuploidy to single-gene disorders. Examples of single-gene disorders include various skeletal dysplasias, sickle cell disease and cystic fibrosis. Although this tec...

Genetic Syndromes and Gynecologic Implications in Adolescents

Feb 20th, 2019 - As adolescents with a genetic syndrome transition to adult medical care, they may be referred to obstetrician–gynecologists for routine preventive or contraceptive services, screening, or counseling for sexually transmitted infection, or for menstrual management. Although some genetic syndromes have no physical or intellectual impairment, others have significant ones; therefore, education and g.

Measles- IDSA

Feb 11th, 2019 - The declaration of a public health emergency in the state of Washington in January 2019, after confirmation of 26 measles cases there, follows a report in December 2018 showing steep climbs and severe outbreaks of the virus worldwide. The spread of measles reflects stalled vaccination coverage, continued vaccine avoidance, and the need for intensive community education on the safety and effecti...

Sleep Problems in 2- to 5-Year-Olds With Autism Spectrum Disorder and Other Developmental Delays
Reynolds, A.

Feb 10th, 2019 - Sleep problems can impact daytime behavior, quality of life, and overall health. We compared sleep habits in young children with autism spectrum disorder (ASD) and other developmental delays and disorders and in children from the general population (POP). We included 2- to 5-year-old children whose parent completed all items on the Children’s Sleep Habits Questionnaire (CSHQ) in a multisite cas...

American Medical Society for Sports Medicine Position Statement on Concussion in Sport
Harmon, Kimberly G.

Feb 10th, 2019 - Abstract: Sport-related concussion (SRC) is a common injury in recreational and organized sport. Over the past 30 years, there has been significant progress in our scientific understanding of SRC, which in turn has driven the development of clinical guidelines for diagnosis, assessment, and management of SRC.

ACIP Vaccine Recommendations and Guidelines

Feb 4th, 2019 - The Advisory Committee on Immunization Practices (ACIP) is a group of medical and public health experts that develop recommendations on how to use vaccines to control diseases in the United States

Recommended Adult Immunization Schedule, United States, 2019
Kim, D. et. al.

Feb 4th, 2019 - In October 2018, the Advisory Committee on Immunization Practices (ACIP) voted to approve the Recommended Adult Immunization Schedule, United States, 2019, for adults aged 19 years or older. The 2019 adult immunization schedule, available at www.cdc.gov/vaccines/schedules, summarizes ACIP recommendations in 2 tables and accompanying notes (Figure). The full ACIP recommendations for each vaccine...

Rising cancer incidence in younger adults: is obesity to blame?
Marinac, C. et. al.

Feb 2nd, 2019 - Although cancer has historically been considered a disease of aging, a reported sharp rise in colorectal cancer incidence among adults aged 54 years and younger beginning in the mid-1980s for the colon and mid-1970s for the rectum has motivated researchers to examine risk factors for early onset disease. In The Lancet Public Health, Hyuna Sung and colleagues3 report a rigorous and extensive ana...

Emerging cancer trends among young adults in the USA: analysis of a population-based cancer registry
Sung, H. et. al.

Feb 2nd, 2019 - Cancer trends in younger adults, often under 50 years, reflect recent changes in carcinogenic exposures, which could foreshadow the future overall disease burden. Previous studies reported an increase in early onset colorectal cancer, which could partly reflect the obesity epidemic. We examined age-specific contemporary incidence trends in the USA for 30 common cancers, including 12 obesity-rel...

Effects of Influenza Vaccination in the United States during the 2017–2018 Influenza Season
Rolfes, M. et. al.

Feb 1st, 2019 - The severity of the 2017–2018 influenza season in the U.S. was high with influenza A(H3N2) viruses predominating. We report influenza vaccine effectiveness (VE) and estimate the number of vaccine prevented influenza-associated illnesses, medical visits, hospitalizations, and deaths for the 2017–2018 influenza season.

Home Oxygen Therapy for Children. An Official American Thoracic Society Clinical Practice Guideline
Hayes, D. et. al.

Jan 31st, 2019 - Although home oxygen therapy is commonly required in the care of children, there is a striking lack of empirical evidence regarding implementation, monitoring, and discontinuation of supplemental oxygen therapy. The panel formulated and provided the rationale for clinical recommendations for home oxygen therapy based on scant empirical evidence, expert opinion, and clinical experience to aid cl...

Hepatitis, Nonalcoholic Steatohepatitis
Sharma, B. et. al.

Jan 31st, 2019 - Nonalcoholic, fatty liver disease (NAFLD) is defined as the ectopic accumulation of fat in the liver (hepatic steatosis) when no other causes of secondary, liver fat accumulation are present. As minor deposition of fat can occur in healthy adults, deposition of fat in at least 5% of hepatocytes is considered pathologic. Nonalcoholic steatohepatitis (NASH) is diagnosed via a liver biopsy when th...

Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials
Sievert, K. et. al.

Jan 29th, 2019 - This study suggests that the addition of breakfast might not be a good strategy for weight loss, regardless of established breakfast habit. Caution is needed when recommending breakfast for weight loss in adults, as it could have the opposite effect. Further randomised controlled trials of high quality are needed to examine the role of breakfast eating in the approach to weight management.

The Link Between School Attendance and Good Health
Allison, M. et. al.

Jan 27th, 2019 - More than 6.5 million children in the United States, approximately 13% of all students, miss 15 or more days of school each year. The rates of chronic absenteeism vary between states, communities, and schools, with significant disparities based on income, race, and ethnicity. Chronic school absenteeism, starting as early as preschool and kindergarten, puts students at risk for poor school perfo...

Economic burden of food allergy- A systematic review

Jan 27th, 2019 - Food allergy (FA) is a life-threatening condition that is a growing health concern worldwide. Currently in the United States, 8% of children have a parent-reported FA.1 Much of the epidemiological work on FA has focused primarily on children; however, recent estimates have found that 10.8% of adults in the US have a self-reported FA.2 Furthermore, numerous studies have estimated the prevalence ...

Association of Childhood Lead Exposure With Adult Personality Traits and Lifelong Mental Health
Reuben, A. et. al.

Jan 22nd, 2019 - Question: Is childhood lead exposure associated with the risk of mental illness or difficult personality traits in adulthood? Findings: In this longitudinal cohort study of 579 New Zealand children followed up for more than 30 years, greater lead exposure in childhood was significantly associated with greater psychopathology across the life course and with difficult personality traits in adulth...

Human Papillomavirus Vaccine Effectiveness and Herd Protection in Young Women
Spinner, C. et. al.

Jan 21st, 2019 - Clinical trials of the 4-valent human papillomavirus (HPV) vaccine demonstrate high efficacy, but surveillance studies are essential to examine the long-term impact of vaccine introduction on HPV prevalence in community settings. The aims of this study were to determine during the 11 years after vaccine introduction the prevalence of (1) vaccine-type HPV in adolescent and young adult women who ...

Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children
Davidovics, Z. et. al.

Jan 21st, 2019 - Fecal microbiota transplantation (FMT) is becoming part of the treatment algorithms against recurrent Clostridium difficile infection (rCDI) both in adult and pediatric gastroenterology practice. With our increasing recognition of the critical role the microbiome plays in human health and disease, FMT is also being considered as a potential therapy for other disorders, including inflammatory bo...

Initiative to Improve Exclusive Breastfeeding by Delaying the Newborn Bath
DiCioccio, H. et. al.

Jan 20th, 2019 - Objective: To examine whether delayed newborn bathing would increase rates of in-hospital exclusive breastfeeding and plans to use human milk at discharge.Design: A retrospective, two-group, pre- and postintervention design. Setting/Local Problem: At our facility, the initial bath was completed within 2 hours of birth, and the rate of in-hospital exclusive breastfeeding was low. Participants: C...

Ten threats to global health in 2019

Jan 20th, 2019 - The world is facing multiple health challenges. These range from outbreaks of vaccine-preventable diseases like measles and diphtheria, increasing reports of drug-resistant pathogens, growing rates of obesity and physical inactivity to the health impacts of environmental pollution and climate change and multiple humanitarian crises.

Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Exposed and H...
Office of AIDS Research Advisory Council

Jan 8th, 2019 - This report updates the last version of the Guidelines for the Prevention and Treatment of Opportunistic Infections (OIs) in HIV-Exposed and HIV-Infected Children, published in 2013. 1 These guidelines are intended for use by clinicians and other health-care workers providing medical care for children living with HIV (CLHIV) and children exposed to but not infected by HIV in the United States.

Body Piercing Infections - StatPearls
Preslar, D.et al

Jan 5th, 2019 - Body piercings have become increasingly popular and a socially acceptable form of body modification. The most common site of piercings is the ear, with increasing popularity involving the mouth, nose, eyebrows, nipples, navel, and genitals. Localized cellulitis is the most common infectious complication resulting from body piercings. If not identified and treated accordingly these localized in...

Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in patients with solid tumors, vaccinated before or during chemotherapy: A randomized trial
Vink, P.

Dec 31st, 2018 - The adjuvanted recombinant zoster vaccine (RZV) has demonstrated >90% efficacy against herpes zoster in adults ≥50 years of age and 68% efficacy in autologous hematopoietic stem cell transplant recipients ≥18 years of age. We report the immunogenicity and safety of RZV administered to patients with solid tumors (STs) before or at the start of a chemotherapy cycle.

Imaging of Kidney Cysts and Cystic Kidney Diseases in Children: An International Working Gro...

Dec 31st, 2018 - Kidney cysts can manifest as focal disease (simple and complex kidney cysts), affect a whole kidney (eg, multicystic dysplastic kidney or cystic dysplasia), or manifest as bilateral cystic disease (eg, autosomal recessive polycystic kidney disease [ARPKD] or autosomal dominant polycystic kidney disease [ADPKD]). In children, as opposed to adults, a larger proportion of kidney cysts are due to g.

Obesity as a Disease: The Obesity Society 2018 Position Statement

Dec 19th, 2018 - The emerging obesity epidemic and accompanying health consequences led The Obesity Society (TOS) in 2008 to publish a position paper defining obesity as a disease. Since then, new information has emerged on the underlying mechanisms leading to excess adiposity and the associated structural, cardiometabolic, and functional disturbances.

2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza

Dec 18th, 2018 - These clinical practice guidelines are an update of the guidelines published by the Infectious Diseases Society of America (IDSA) in 2009, prior to the 2009 H1N1 influenza pandemic. This document addresses new information regarding diagnostic testing, treatment and chemoprophylaxis with antiviral medications, and issues related to institutional outbreak management for seasonal influenza. It is ...

Summary of Revisions: Standards of Medical Care in Diabetes—2019

Dec 18th, 2018 - The field of diabetes care is rapidly changing as new research, technology, and treatments that can improve the health and well-being of people with diabetes continue to emerge. With annual updates since 1989, the American Diabetes Association (ADA) has long been a leader in producing guidelines that capture the most current state of the field. To that end, the “Standards of Medical Care in Dia...

Diabetes Advocacy: Standards of Medical Care in Diabetes—2019

Dec 18th, 2018 - Managing the daily health demands of diabetes can be challenging. People living with diabetes should not have to face additional discrimination due to diabetes. By advocating for the rights of those with diabetes at all levels, the American Diabetes Association (ADA) can help to ensure that they live a healthy and productive life. A strategic goal of the ADA is that more children and adults wit...

Children and Adolescents: Standards of Medical Care in Diabetes—2019

Dec 18th, 2018 - The management of diabetes in children and adolescents cannot simply be derived from care routinely provided to adults with diabetes. The epidemiology, pathophysiology, developmental considerations, and response to therapy in pediatric-onset diabetes are different from adult diabetes. There are also differences in recommended care for children and adolescents with type 1 as opposed to type 2 di...

Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2019

Dec 18th, 2018 - Population health is defined as “the health outcomes of a group of individuals, including the distribution of health outcomes within the group”; these outcomes can be measured in terms of health outcomes (mortality, morbidity, health, and functional status), disease burden (incidence and prevalence), and behavioral and metabolic factors (exercise, diet, A1C, etc.) (1). Clinical practice recomme...

Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2019

Dec 18th, 2018 - Type 1 diabetes and type 2 diabetes are heterogeneous diseases in which clinical presentation and disease progression may vary considerably. Classification is important for determining therapy, but some individuals cannot be clearly classified as having type 1 or type 2 diabetes at the time of diagnosis. The traditional paradigms of type 2 diabetes occurring only in adults and type 1 diabetes o...

Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2019

Dec 18th, 2018 - Screening for prediabetes and type 2 diabetes risk through an informal assessment of risk factors (Table 2.3) or with an assessment tool, such as the American Diabetes Association risk test (Fig. 2.1), is recommended to guide providers on whether performing a diagnostic test for prediabetes (Table 2.5) and previously undiagnosed type 2 diabetes (Table 2.2) is appropriate (see Section 2 “Classif...

Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2019

Dec 17th, 2018 - In the hospital, both hyperglycemia and hypoglycemia are associated with adverse outcomes, including death. Therefore, inpatient goals should include the prevention of both hyperglycemia and hypoglycemia. Hospitals should promote the shortest safe hospital stay and provide an effective transition out of the hospital that prevents acute complications and readmission.

Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2019

Dec 17th, 2018 - There is strong and consistent evidence that obesity management can delay the progression from prediabetes to type 2 diabetes (1–5) and is beneficial in the treatment of type 2 diabetes (6–17). In patients with type 2 diabetes who are overweight or obese, modest and sustained weight loss has been shown to improve glycemic control and to reduce the need for glucose-lowering medications (6–8). Sm...

Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2019

Dec 17th, 2018 - A successful medical evaluation depends on beneficial interactions between the patient and the care team. The Chronic Care Model (1–3) (see Section 1 “Improving Care and Promoting Health in Populations”) is a patient-centered approach to care that requires a close working relationship between the patient and clinicians involved in treatment planning. People with diabetes should receive health c...

Lifestyle Management: Standards of Medical Care in Diabetes—2019

Dec 17th, 2018 - DSMES services facilitate the knowledge, skills, and abilities necessary for optimal diabetes self-care and incorporate the needs, goals, and life experiences of the person with diabetes. The overall objectives of DSMES are to support informed decision making, self-care behaviors, problem-solving, and active collaboration with the health care team to improve clinical outcomes, health status, an...

AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm

Dec 14th, 2018 - This algorithm for the comprehensive management of persons with type 2 diabetes (T2D) was developed to provide clinicians with a practical guide that considers the whole patient, his or her spectrum of risks and complications, and evidence-based approaches to treatment. It is now clear that the progressive pancreatic beta-cell defect that drives the deterioration of metabolic control over time ...

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection
Office of AIDS Research Advisory Council

Dec 13th, 2018 - The Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection (Pediatric Guidelines) address the use of antiretroviral therapy (ART) for children living with HIV, including adolescents with sexual maturity rating (SMR, formerly Tanner staging) I to III (the guidelines developed by the Panel on Antiretroviral Guidelines for Adults and Adolescents are suitable for the care and ma.

The Asthma Controller Step-down Yardstick
Chipps, B.,et al

Dec 10th, 2018 - Asthma guidelines recommend a control-based approach to disease management in which the assessment of impairment and risk is linked to step-based therapy. Using this model, controller treatment is adjusted—upward or downward—according to a patient's level of asthma control over time.

Recommendations for the Use of Antiretroviral Drugs in Pregnant Women with HIV Infection and...
Office of AIDS Research Advisory Council

Dec 6th, 2018 - Recommendations regarding HIV screening in pregnancy, treatment of pregnant women who are living with HIV, and the use of antiretroviral (ARV) drugs for prevention of perinatal transmission of HIV have evolved considerably in the United States since the mid-1990s, reflecting changes in both the epidemic and also in the science of prevention and treatment. With the implementation of recommendati.

HPV Vaccination for Males and Females
American Urological Association

Nov 30th, 2018 - Based on the prevalence and significance of HPV infection and its sequelae as well as the safety and efficacy of HPV vaccines, the American Urological Association (AUA) supports routine immunization with HPV vaccine for boys and girls 11 through 12 years of age. In addition, the AUA recommends the vaccination of others not previously vaccinated aged 13 through 26 years in accordance with nation.

Management of Neonates Born at ?34 6/7 Weeks’ Gestation With Suspected or Proven Early-Onset...
Puopolo, Karen M.

Nov 30th, 2018 - Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born preterm, particularly among newborn infants of the lowest gestational age. Currently, most preterm infants with very low birth weight are treated empirically with antibiotics for risk of EOS, often for prolonged periods, in the absence of a culture-confirmed infection.

Screening Examination of Premature Infants for Retinopathy of Prematurity
Fierson, W.

Nov 30th, 2018 - This policy statement revises a previous statement on screening of preterm infants for retinopathy of prematurity (ROP) that was published in 2013. ROP is a pathologic process that occurs in immature retinal tissue and can progress to a tractional retinal detachment, which may then result in visual loss or blindness.

Vibrio Cholerae - StatPearls

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hypovolemic shock and metabolic acidosis.