Gastroenterology Hadjiliadis D, Khoruts A et. al.
Dec 31st, 2017 - Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5-10 times greater compared to the general population, and 25-30 times greater in CF patients after an organ transplantation. To address this risk, the CF Foundation convened a multi-stakeholder task force to develop CRC screening recommendatio...
Cancer Network; Slater H
Nov 17th, 2019 - The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), along with Tufts Medical Center, Fox Chase Cancer Center, and MD Anderson Cancer Center, announced a new clinical trial aiming to reduce malnutrition among patients with lung cancer by offering nutritional counseling and medically tailored meals to patie...
Nephrology Dialysis Transplantation; Kalantar-Zadeh K, et al
Nov 6th, 2019 - How often have you been told to eat more protein and less carbohydrates to stay healthy? This is not an emerging food culture but rather a prevailing dogma in our society. Physicians, dietitians and other health care professionals tell us constantly about the advantages of a high-protein diet (HPD), such as losing weight rapidly, burning calories, diminishing appetite, preventing obesity, manag...
Oct 28th, 2019 - Shingles (also known as herpes zoster) results from infection by the varicella zoster virus. This common virus causes chickenpox (also known as varicella), which is characterized by itchy spots on the skin that cover the whole body and usually occurs in childhood or adolescence. After the body fights the initial infection, the varicella zoster virus remains in nerve cells for the rest of a per...
Pediatrics Armstrong, S. et. al.
Oct 27th, 2019 - Severe obesity among youth is an “epidemic within an epidemic” and portends a shortened life expectancy for today’s children compared with those of their parents’ generation. Severe obesity has outpaced less severe forms of childhood obesity in prevalence, and it disproportionately affects adolescents. Emerging evidence has linked severe obesity to the development and progression of multiple co...
Medical Clinics of North America; Nanda A, et al
Oct 27th, 2019 - Asthma affects approximately 300 million people worldwide and approximately 7.5% of adults in the United States. Among adults, asthma results in about 10.5 million physician office visits per year and affects approximately 8.7% of blacks, 7.6% of whites, and 5.8% of Hispanics. Asthma is characterized by inflammation of airways, variable airflow obstruction, and bronchial hyperresponsiveness.3 I...
Oct 16th, 2019 - Single-dose Xofluza is the first and only antiviral medicine indicated specifically for patients at high risk of developing serious complications from influenza (flu) The Centers for Disease Control and Prevention (CDC) defines people at high risk of serious flu complications as those who have conditions such as asthma, chronic lung disease, diabetes, heart disease, morbid obesity or adults ...
BMJ Chen, C. et. al.
Oct 15th, 2019 - Objective To investigate the association between weight changes across adulthood and mortality. Design Prospective cohort study. Setting US National Health and Nutrition Examination Survey (NHANES) 1988-94 and 1999-2014. Participants 36 051 people aged 40 years or over with measured body weight and height at baseline and recalled weight at young adulthood (25 years old) and middle adul...
JAMA Cardiology; Chen, Y. et. al.
Oct 15th, 2019 - Question How have the trends in premature mortality from cardiovascular disease (CVD) changed in the United States during 2000 to 2015 by demographics and county-level factors, including education, rurality, and the prevalence of smoking, obesity, and diabetes? Findings In this study, CVD mortality rates increased significantly among American Indian/Alaska Native individuals age 25 to 49 y...
Morbidity and Mortality Weekly Report; Patel, M. et. al.
Oct 3rd, 2019 - What is already known about this topic? Measles was eliminated in the United States in 2000. High national coverage with measles, mumps, and rubella vaccine and rapid implementation of measles control measures prevent widespread measles transmission. What is added by this report? During January–September 2019, 1,249 U.S. measles cases were reported, the highest annual number since 1992...
Journal of the American College of Cardiology; Shapiro, M. et. al.
Oct 1st, 2019 - Although significant progress has been made to reduce the global burden of cardiovascular disease, efforts have focused primarily on treatment of manifest disease rather than on prevention of events. An enormous opportunity exists to transition focus from intervention to providing equal attention to prevention of cardiovascular disease. The nascent specialty of “preventive cardiology” is emergi...
American Family Physician; Saguil, A. et. al.
Sep 30th, 2019 - Hand-foot-and-mouth disease is caused by human enteroviruses and coxsackieviruses. Outbreaks can occur in the spring to fall and are common in North America, and most cases occur in patients younger than 10 years. Hand-foot-and-mouth disease is transmitted by fecal-oral, oral-oral, and respiratory droplet contact. Patients present with a low-grade fever, a maculopapular or papulovesicular rash ...
Sep 29th, 2019 - The 2019 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel of experts on the GINA Science Committee. This comprehensive and practical resource about one of the most common chronic lung diseases worldwide contains extensive citations from the scientifi...
Sep 25th, 2019 - David J. Amrol, MD reviewing Hardy J et al. Lancet 2019 Sep 14 Gauthier M and Wenzel SE. Lancet 2019 Sep 14
Sep 15th, 2019 - BACKGROUND: Donepezil, rivastigmine and galantamine are popular cholinesterase inhibitors used to manage the symptoms of Alzheimer disease and other dementias; regulatory agencies in several countries warn about a possible risk of rhabdomyolysis with donepezil, based on information from case reports. Our goal was to investigate the 30-day risk of admission to hospital with rhabdomyolysis associ...
Sep 11th, 2019 - GlaxoSmithKline (LSE/NYSE: GSK) today announced that the US Food and Drug Administration (FDA) has approved Nucala (mepolizumab) for use in children as young as six years old who are living with severe eosinophilic asthma. Nucala is the only targeted biologic to be approved for the condition in the six to 11-year age group in the US.
Sep 11th, 2019 - In 2018, nine states reported an adult obesity prevalence at or above 35 percent: Alabama, Arkansas, Iowa, Kentucky, Louisiana, Mississippi, Missouri, North Dakota, and West Virginia. This comes from the new obesity prevalence maps released today by the Centers for Disease Control and Prevention.
Annals of The Royal College of Surgeons of England; Hay D, et al
Sep 5th, 2019 - Intragastric balloons have been used as an invasive non-surgical treatment for obesity for over 30 years. Within the last 37 years, we have found only 27 cases reported in the literature of intestinal obstruction caused by a migrated intragastric balloon. We report the laparoscopic management of such a case and make observations from similar case presentations published in the literature. A ...
Aug 25th, 2019 - 2018 - 2019 Measles Outbreak in Rockland County: As of August 26, 2019, there are 312* confirmed reported cases of measles in Rockland County. *On Monday, August 26, 2019, 16 historical cases of measles were added to the current total. These cases occurred between early February 2019 and mid-May 2019.
Aug 11th, 2019 - The U.S. Food and Drug Administration is warning consumers not to purchase or drink a product sold online as a medical treatment due to a recent rise in reported health issues. Since 2010, the FDA has warnedExternal Link Disclaimer consumers about the dangers of Miracle or Master Mineral Solution, Miracle Mineral Supplement, MMS, Chlorine Dioxide (CD) Protocol, Water Purification Solution (WPS)...
American Family Physician;
Jul 28th, 2019 - Measles is one of the most highly transmissible diseases, with 90% of unvaccinated persons infected after contact.1 In 2000, the Centers for Disease Control and Prevention (CDC) declared that measles was eliminated in the United States, but that elimination status may be revoked if the current chain of measles transmission and outbreaks continues for one year, through the fall of 2019. As ...
Jul 17th, 2019 - Measles is one of the most easily transmitted viruses known to man. It spreads via the respiratory system – much like influenza and TB. An infected person coughs the virus and others inhale it. The measles virus remains infectious in the air up to two hours after the infectious individual has left the area.
Jul 16th, 2019 - Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved RECARBRIO™ (imipenem, cilastatin, and relebactam) for injection, 1.25 grams, a new combination antibacterial. RECARBRIO is indicated in patients 18 years of age and older who have limited or no alternative treatment options, for the treatment of comp...
The Journal of Allergy and Clinical Immunology: In Practice; Raita, Y. et. al.
Jul 15th, 2019 - Background Patients with asthma have a high incidence of acute myocardial infarction and ischemic stroke. Objective To investigate the acute effect of asthma exacerbation on these cardiovascular events. Methods Using population-based inpatient data of 3 geographically diverse US states (Florida, Nebraska, and New York) during the period 2011 to 2014, we conducted a self-controlled case...
Jul 15th, 2019 - Polycystic kidney disease is a disorder that affects the kidneys and other organs. Clusters of fluid-filled sacs, called cysts, develop in the kidneys and interfere with their ability to filter waste products from the blood. The growth of cysts causes the kidneys to become enlarged and can lead to kidney failure. Cysts may also develop in other organs, particularly the liver.
Jul 14th, 2019 - Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA) announced today that the U.S. Food and Drug Administration (FDA) has approved AirDuo® Digihaler™ (fluticasone propionate 113 mcg and salmeterol 14 mcg) Inhalation Powder, a combination therapy digital inhaler with built-in sensors that connects to a companion mobile application to provide information on inhaler use to people with asthma....
Jul 12th, 2019 - Our objective was to compare obesity prevalence among human immunodeficiency virus (HIV)-infected adults receiving care and the U.S. general population and identify obesity correlates among HIV-infected men and women. Cross-sectional data was collected in 2009 to 2010 from 2 nationally representative surveys: Medical Monitoring Project (MMP) and National Health and Nutrition Examination Surv...
Jun 29th, 2019 - Autosomal Dominant Polycystic Kidney Disease (ADPKD) resulted in end-stage renal disease (ESRD) by age 53, on average, and was responsible for 6 percent of ESRD cases in the U.S.
Jun 26th, 2019 - NUCALA (mepolizumab) has clinical data on exacerbation reduction. Learn about NUCALA for patients with severe eosinophilic asthma.
Jun 24th, 2019 - Atopic dermatitis is a chronic, itchy skin condition that is very common in children but may occur at any age. It is also known as eczema and atopic eczema and was formerly known as Besnier prurigo. It is the most common form of dermatitis. Atopic dermatitis usually occurs in people who have an 'atopic tendency'. This means they may develop any or all of three closely linked conditions; atop...
May 29th, 2019 - Today, CDC is reporting 971 cases of measles in the United States thus far in 2019. This is the greatest number of cases reported in the U.S. since 1994, when 963 cases were reported for the entire year. CDC continues to work with affected state and local health departments to get ongoing outbreaks under control.
The Cochrane Database of Systematic Reviews; Threapleton, C. et. al.
May 23rd, 2019 - Chronic obstructive pulmonary disease (COPD; including chronic bronchitis and emphysema) is a chronic respiratory condition characterised by shortness of breath, cough and recurrent exacerbations. Long‐term antibiotic use may reduce both bacterial load and inflammation in the airways. Studies have shown a reduction of exacerbations with antibiotics in comparison to placebo in people with COPD, ...
Cancer Spectrum; Zhang, F. et. al.
May 21st, 2019 - Diet is an important risk factor for cancer that is amenable to intervention. Estimating the cancer burden associated with diet informs evidence-based priorities for nutrition policies to reduce cancer burden in the US. Methods Using a Comparative Risk Assessment model that incorporated nationally representative data on dietary intake, national cancer incidence, and estimated associations o...
May 2nd, 2019 - Racial and ethnic disparities in severe maternal morbidity — life-threatening maternal complications associated with childbirth — have persisted and increased at high rates among U.S. women, according to an analysis of nearly 20 years of California hospital records funded by the National Institutes of Health. Known risk factors for these complications — such as blood pressure disorders, asthma ...
Apr 25th, 2019 - The United States is currently experiencing the greatest number of reported cases of measles, also known as rubeola, since the disease was eliminated in 20001. Outbreaks have been confirmed in 22 states and the number of cases and their distribution is increasing rapidly. These measles outbreaks have been linked to travelers bringing back cases of measles from other countries. This situation co...
Apr 22nd, 2019 - BAROnova, Inc., a medical device company focused on the development of first-in-class non-surgical solutions for the treatment of obesity, announced today that the U.S. Food and Drug Administration (FDA) has approved the TransPyloric Shuttle® (TPS®) Device, a non-surgical weight loss solution for adult individuals suffering from obesity with a body mass index (BMI) of 30 to 40 kg/m2. The device...
Apr 14th, 2019 - Measles, Also Known As Rubeola, Is A Highly Contagious Airborne Viral Illness That Infects Approximately Nine Out Of Ten Exposed Susceptible Individuals. Measles Infection Was Common Until The Measles, Mumps, And Rubella (MMR) Vaccine Was Licensed In 1963 And Became Part Of The Routine Immunization Schedule. By 2000, Measles Was Essentially Eliminated From The United States. In The Last Decade,...
Apr 13th, 2019 - Gelesis, a biotechnology company developing first-in-class hydrogel therapeutics to treat obesity and other chronic diseases related to the gastrointestinal (GI) tract, today announced that the United States Food and Drug Administration (FDA) has cleared the Company’s lead product candidate, PLENITY™ (Gelesis100), as an aid in weight management in adults with a Body Mass Index (BMI) of 25–40 k...
Apr 2nd, 2019 - Types of DTC genetic tests A broad range of genetic test types are offered DTC, including: Carrier testing for diseases such as cystic fibrosis and hemochromatosis Pharmacogenomic testing Testing for predisposition to complex diseases such as hereditary cancers, cardiovascular disease and depression Whole exome or genome sequencing Testing to determine ancestry
Mar 31st, 2019 - Measles Cases in 2019 From January 1 to February 21, 2019, 159** individual cases of measles have been confirmed in 10 states. In a given year, more measles cases can occur for any of the following reasons: an increase in the number of travelers who get measles abroad and bring it into the U.S., and/or further spread of measles in U.S. communities with pockets of unvaccinated people.
Mar 31st, 2019 - On World Autism Awareness Day, we speak out against discrimination, celebrate the diversity of our global community and strengthen our commitment to the full inclusion and participation of people with autism. Supporting them to achieve their full potential is a vital part of our efforts to uphold the core promise of the 2030 Agenda for Sustainable Development: to leave no one behind
Mar 31st, 2019 - Autism Spectrum Disorder (ASD) is a developmental disability that can cause significant social, communication and behavioral challenges. CDC is working to find out how many children have ASD, discover the risk factors, and raise awareness of the signs.
Benson, A. et. al.
Mar 31st, 2019 - Incidence and mortality rates for cancer overall are declining, but both incidence and mortality rates for hepatocellular carcinoma (HCC) are increasing.1,2 Risk factors for development of HCC include infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV), and cirrhosis of the liver (eg, alcohol cirrhosis).3 Metabolic disorders (ie, obesity, diabetes, impaired glucose metabolism,...
Biomedicines Jones L, et al
Mar 27th, 2019 - The gut microbiota is extremely important for the health of the host across its lifespan.Recent studies have elucidated connections between the gut microbiota and neurological diseaseand disorders such as depression, anxiety, Alzheimer's disease (AD), autism, and a host of otherbrain illnesses. Dysbiosis of the normal gut flora can have negative consequences for humans,especially throughout key...
Mar 24th, 2019 - The latest national and state data on the burden of asthma among children and adults.
McGrew, C.,et al
Mar 18th, 2019 - This American Medical Society for Sports Medicine position statement update is directed towards healthcare providers of patients involved in sport and exercise. There have been significant advances in clinical and scientific research in the understanding of blood-borne pathogens (BBPs), and this update incorporates these advancements.
Mar 17th, 2019 - This clinical report updates and replaces a 2008 clinical report from the American Academy of Pediatrics, which addressed the roles of maternal and early infant diet on the prevention of atopic disease, including atopic dermatitis, asthma, and food allergy. As with the previous report, the available data still limit the ability to draw firm conclusions about various aspects of atopy prevention ...
Mar 14th, 2019 - Mumps is a viral illness caused by a paramyxovirus, a member of the Rubulavirus family. The average incubation period for mumps is 16 to 18 days, with a range of 12 to 25 days.
Mar 13th, 2019 - The American Academy of Pediatrics (AAP) will advise families to vaccinate their children against influenza next season with either the flu shot or the nasal spray vaccine for the best protection against the virus during the 2019-2020 flu season. The recommendation differs slightly from last year, when AAP cited a preference for the injected vaccine over the nasal spray - except in cases whe...
Emerging Infectious Diseases; Weigand, M. et. al.
Mar 12th, 2019 - We characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurring amid the current pertussis disease resurgence and provide a foundation for needed research to direct future public health control strategies.