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About 1,168 results

ALLMedicine™ Hereditary Spastic Paraplegia Center

Research & Reviews  460 results

Iron-sensitive MR imaging of the primary motor cortex to differentiate hereditary spast...
https://doi.org/10.1007/s00330-022-08865-6 10.1016/S1474-4422(19)30235-2 10.1007/s10072-020-04981-7 10.1007/s11910-021-01099-x 10.1007/s12311-016-0803-z 10.1111/j.1365-2990.2004.00587.x 10.1016/S1474-4422(08)70258-8 10.1136/jnnp.37.1.8 10.1016/0303-8467(92)90010-Z 10.1001/archneurpsyc.1956.02330200038005 10.1007/s004010000255 10.1212/WNL.55.1.89 10.1055/s-2001-15265 10.1136/jnnp.44.10.871 10.1001/archneurol.2009.19 10.3390/brainsci11050611 10.3174/ajnr.A2043 10.1016/j.expneurol.2011.12.024 10.1371/journal.pone.0035241 10.3174/ajnr.A4562 10.1016/j.nicl.2016.04.011 10.3174/ajnr.A5423 10.1016/j.nicl.2019.101934 10.1111/j.1468-1331.2010.02951.x 10.1016/S0140-6736(83)92879-9 10.1212/01.wnl.0000228242.53336.90 10.1136/jnnp-2019-322541 10.1080/146608200300079536 10.1016/S0022-510X(99)00210-5 10.2307/2529310 10.1080/14660820410021267 10.1212/01.wnl.0000200962.94777.71 10.3390/brainsci11050578 10.3390/brainsci11030403 10.1007/s00401-013-1115-8 10.1007/s00401-011-0916-x 10.1148/radiol.14141715 10.3389/fneur.2018.01117 10.1007/s00415-015-7791-7 10.1212/01.WNL.0000058901.75728.4E 10.1016/S1474-4422(11)70015-1 10.3174/ajnr.A2067 10.1093/brain/115.2.495 10.1007/s00401-003-0687-0 10.1007/s00401-007-0234-5 10.1001/archneur.1981.00510100058008 10.1111/j.1440-1789.1997.tb00042.x 10.1016/j.nicl.2017.10.024 10.1080/21678421.2020.1837173 10.1136/jnnp.2009.201103 10.1016/j.jns.2009.09.025 10.3389/fneur.2018.00981 10.1002/ana.20652 10.1001/jama.2014.14604 10.1186/1471-2350-14-118 10.1002/ana.25263 10.3389/fgene.2019.00434 10.1212/01.wnl.0000338530.77394.60 10.1002/ana.23641
European Radiology; Cosottini M, Donatelli G et. al.

May 21st, 2022 - Hereditary spastic paraplegia (HSP) is a group of genetic neurodegenerative diseases characterised by upper motor neuron (UMN) impairment of the lower limbs. The differential diagnosis with primary lateral sclerosis (PLS) and amyotrophic lateral s...

Genetic origin of patients having spastic paraplegia with or without other neurologic m...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109329
BMC Neurology; Chen J, Zhao Z et. al.

May 17th, 2022 - Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases characterized by lower-limb spastic paraplegia with highly genetic and clinical heterogeneity. However, the clinical sign of spastic paraplegia can also be seen in a vari...

Childhood-onset writer's cramp in hereditary spastic paraplegia type 15.
https://doi.org/10.1017/cjn.2022.59
The Canadian Journal of Neurological Sciences. Le Journal... Moura J, Sardoeira A et. al.

May 12th, 2022 - Childhood-onset writer's cramp in hereditary spastic paraplegia type 15.|2022|Moura J,Sardoeira A,Oliveira J,Mendes A,Barros J,|

Cytoskeleton saga: Its regulation in normal physiology and modulation in neurodegenerat...
https://doi.org/10.1016/j.ejphar.2022.175001
European Journal of Pharmacology; Sen S, Lagas S et. al.

May 8th, 2022 - Cells are fundamental units of life. To ensure the maintenance of homeostasis, integrity of structural and functional counterparts is needed to be essentially balanced. The cytoskeleton plays a vital role in regulating the cellular morphology, sig...

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
https://clinicaltrials.gov/ct2/show/NCT05354622

May 4th, 2022 - The hereditary spastic paraplegias (HSP) are a group of more than 80 inherited neurogenetic diseases that share the common feature of progressive spasticity. Collectively, the HSPs present the most common cause of inherited spasticity and associat...

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Clinicaltrials.gov  6 results

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
https://clinicaltrials.gov/ct2/show/NCT05354622

May 4th, 2022 - The hereditary spastic paraplegias (HSP) are a group of more than 80 inherited neurogenetic diseases that share the common feature of progressive spasticity. Collectively, the HSPs present the most common cause of inherited spasticity and associat...

Phenotype, Genotype and Biomarkers 2
https://clinicaltrials.gov/ct2/show/NCT04875416

Apr 7th, 2022 - The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (PLS), hereditary spastic paraplegia (HSP), progr...

Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31
https://clinicaltrials.gov/ct2/show/NCT02859428

Oct 20th, 2020 - The Neurogenetics Branch (NGB) within the National Institute of Neurological Disorders and Stroke (NINDS) is conducting a study to evaluate patients with hereditary spastic paraplegia types 3A, 4 and 31. The objective of this study is to understan...

Physiotherapy in Hereditary Spastic Paraplegia
https://clinicaltrials.gov/ct2/show/NCT03961906

May 23rd, 2019 - This is a randomized single-center parallel study with a control group design. A blinded block randomization in groups of four was performed in equal parts toward the treatment (TPC) or the control (regular standard-of-care) group using randomizat...

Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia
https://clinicaltrials.gov/ct2/show/NCT02604186

Nov 7th, 2017 - Introduction Hereditary spastic paraplegias (SPG) constitute a heterogeneous group of diseases with a common predominant feature: spasticity of the lower limbs and difficulty walking. The neurologic examination reveals spasticity, exaggerated and ...

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News  1 results

New Compound Promising for ALS, Other Upper Motor Neuron Diseases
https://www.medscape.com/viewarticle/947056

Mar 11th, 2021 - NEW YORK (Reuters Health) - A new compound, NU-9, improved diseased upper motor neurons (UMN) in mice and shows promise for treating amyotrophic lateral sclerosis (ALS) in humans, though more work is needed before a clinical trial can be started, ...

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