×
About 498 results

ALLMedicine™ Dystonias Center

Research & Reviews  182 results

Long-Term Outcomes of Deep Brain Stimulation for Pediatric Dystonia.
https://doi.org/10.1159/000524577
Pediatric Neurosurgery; Malatt C, Tagliati M

Apr 20th, 2022 - Background Deep brain stimulation (DBS) has been utilized for over two decades to treat medication refractory dystonia in children. Short-term benefit has been demonstrated for inherited, isolated and idiopathic cases, with less efficacy in heredo...

Paroxysmal limb dystonias associated with GABBR2 pathogenic variant: A case-based liter...
https://doi.org/10.1016/j.braindev.2022.03.010
Brain & Development; D'Onofrio G, Riva A et. al.

Apr 14th, 2022 - De novo mutations in the GABBR2 (Gamma-Aminobutyric acid Type B Receptor Subunit 2) gene have recently been reported to be associated with a form of early-infantile epileptic encephalopathy (EIEE59; OMIM# 617904), as well as a Rett syndrome (RTT)-...

Neuropsychological Functioning in Primary Dystonia: Updated and Expanded Multidomain Me...
https://doi.org/10.1002/mds.29022
Movement Disorders : Official Journal of the Movement Dis... Aita SL, Del Bene VA et. al.

Apr 7th, 2022 - Primary dystonia is conventionally considered as a motor disorder, though an emerging literature reports associated cognitive dysfunction. Here, we conducted meta-analyses on studies comparing clinical measures of cognition in persons with primary...

Brain-Computer Interfaces in Laryngeal Dystonia
https://clinicaltrials.gov/ct2/show/NCT04421365

Mar 31st, 2022 - Dystonia is a neurological disorder, which causes involuntary, sustained muscle contractions, resulting in uncontrollable twisting, repetitive movements, and abnormal postures. Selective impairment of motor control of highly skilled and goal-orien...

A dystonia mouse model with motor and sequencing deficits paralleling human disease.
https://doi.org/10.1016/j.bbr.2022.113844
Behavioural Brain Research; Kernodle K, Bakerian AM et. al.

Mar 20th, 2022 - The dystonias are a group of movement disorders characterized by involuntary twisting movements and postures. A lack of well characterized behavioral models of dystonia has impeded identification of circuit abnormalities giving rise to the disease...

see more →

Guidelines  1 results

EFNS guidelines on diagnosis and treatment of primary dystonias.
https://doi.org/10.1111/j.1468-1331.2010.03042.x
European Journal of Neurology; Albanese A, Asmus F et. al.

May 21st, 2010 - to provide a revised version of earlier guidelines published in 2006. primary dystonias are chronic and often disabling conditions with a widespread spectrum mainly in young people. primary dystonias are classified as pure dystonia, dystonia plus ...

see more →

Drugs  1 results see all →

Clinicaltrials.gov  8 results

Brain-Computer Interfaces in Laryngeal Dystonia
https://clinicaltrials.gov/ct2/show/NCT04421365

Mar 31st, 2022 - Dystonia is a neurological disorder, which causes involuntary, sustained muscle contractions, resulting in uncontrollable twisting, repetitive movements, and abnormal postures. Selective impairment of motor control of highly skilled and goal-orien...

rTMS in Spasmodic Dysphonia
https://clinicaltrials.gov/ct2/show/NCT02957942

Oct 1st, 2020 - Focal dystonia is a neurological movement disorder characterized by excessive involuntary muscle contractions of any body part. Spasmodic dysphonia (SD) is a type of focal dystonia characterized by excessive contraction of intrinsic muscles in the...

Dystonia Coalition Projects
https://clinicaltrials.gov/ct2/show/NCT04156022

Nov 7th, 2019 - This collaborative, international effort has two primary goals. The first is to create a biospecimen repository and associated clinical database to be used as a resource for dystonia and related disease research. The second goal is to create and v...

Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia
https://clinicaltrials.gov/ct2/show/NCT00713414

Jul 5th, 2018 - Spasmodic dysphonia (SD) and writer s cramp (WC) are primary focal dystonias with selective impairment of voluntary control of speaking and writing, respectively. Although the pathophysiology of SD and WC is unknown, dystonia is considered to be a...

Imaging Neuromelanin and Iron in Dystonia/Parkinsonism
https://clinicaltrials.gov/ct2/show/NCT03572114

Jun 28th, 2018 - Iron- or Neuromelanin-sensitive MR-imaging has not been consistently applied to the study of syndromes presenting with predominant dystonia/parkinsonism yet. We are planning to study the following groups, as they can often be very difficult to be ...

see more →

News  7 results

Fast Five Quiz: Schizophrenia Management in Adults
https://reference.medscape.com/viewarticle/933512_6

Aug 11th, 2020 - First-generation antipsychotics have a high rate of extrapyramidal side effects, including rigidity, bradykinesia, dystonias, tremor, and akathisia. Tardive dyskinesia —involuntary movements of the face and extremities — is another adverse effect ...

High Rate of Waning Botox Efficacy in Dystonia, Spasticity
https://www.staging.medscape.com/viewarticle/906182

Dec 7th, 2018 - Many patients with dystonia or spasticity who receive botulinum neurotoxin type A (BoNT/A) develop neutralizing antibodies (NABs) to the toxin over time, new research shows. NABs against BoNT/A occur at "surprisingly high rates" during long-term t...

High Rate of Waning Botox Efficacy in Dystonia, Spasticity
https://www.medscape.com/viewarticle/906182

Dec 7th, 2018 - Many patients with dystonia or spasticity who receive botulinum neurotoxin type A (BoNT/A) develop neutralizing antibodies (NABs) to the toxin over time, new research shows. NABs against BoNT/A occur at "surprisingly high rates" during long-term t...

Noncosmetic uses of botulinum toxin in otolaryngology
https://www.mdedge.com/ccjm/article/103773/drug-therapy/noncosmetic-uses-botulinum-toxin-otolaryngology?channel=133
Michael S. Benninger, MD, Libby J. Smith, DO, FAOCO

Nov 1st, 2015 - Botulinum toxin is commonly used to treat movement disorders of the head and neck. It was first used to treat focal eye dystonia (blepharospasm) and laryngeal dystonia (spasmodic dysphonia) and is now also used for other head and neck dystonias, m.

Botulinum Toxin Benefits Many PSP Patients With Dystonia
https://www.medscape.com/viewarticle/806471

Jun 18th, 2013 - BARCELONA, Spain — For patients with progressive supranuclear palsy (PSP), botulinum toxin A injections relieve disabling blepharospasm and neck and hand dystonia, a relatively large retrospective study shows. About three quarters of patients with...

see more →