About 2,220 results

ALLMedicine™ Heterotopic Ossification Center

Research & Reviews  861 results

Results of arthroscopically assisted reduction and fixation of antero-medial coronoid f...
Journal of Shoulder and Elbow Surgery; Colozza A, Menozzi M et. al.

May 14th, 2022 - Varus posteromedial rotatory instability is a typical pattern of elbow injury that involves fracture of the anteromedial facet (AMF) of the coronoid as well as injuries to the lateral ligament complex and the posterior bundle of the medial collate...

Fibrodysplasia Ossificans Progressiva

May 13th, 2022 - Practice Essentials Fibrodysplasia ossificans progressiva (FOP) is a rare, severely disabling, autosomal dominant disease characterized by recurrent painful episodes of soft-tissue swelling and the development of tumors in subcutis and muscle tiss...

Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPL...
Nature Communications; Xu C, Zhang Z et. al.

May 6th, 2022 - Ossification of the posterior longitudinal ligament (OPLL) is an emerging spinal disease caused by heterotopic ossification of the posterior longitudinal ligament. The pathological mechanism is poorly understood, which hinders the development of n...

ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progr...
The Journal of Clinical Investigation; Aykul S, Huang L et. al.

May 6th, 2022 - Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder whose most debilitating pathology is progressive and cumulative heterotopic ossification (HO) of skeletal muscles, ligaments, tendons, and fascia. FOP is caused by mutations in...

American Journal of Physical Medicine & Rehabilitation; Vasileiadis GI, Balta AA et. al.

May 6th, 2022 - The role of kinesiotherapy in heterotopic ossification (HO) remains unclear. The goal of this study is to revisit the literature on the preventive role of kinesiotherapy against HO formation and maturation. A systematic review was performed in MED...

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Drugs  2 results see all →

Clinicaltrials.gov  13 results

Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma

Apr 21st, 2022 - A multi-institutional, prospective randomized clinical trial will be employed to determine if single dose, limited field radiation therapy (XRT) will prevent post-traumatic heterotopic ossification (HO) after open reduction internal fixation of in...

An Open-Label Extension Study of Palovarotene to Prevent Heterotopic Ossification in People With Fibrodysplasia Ossificans Progressiva (FOP) in France

Feb 17th, 2022 - The main objective of this Phase 2, open-label study is to evaluate the safety and efficacy of different palovarotene dosing regimens in participants with FOP in France. Efficacy will be assessed based on the ability of palovarotene to prevent the...

HO Prophylaxis Therapy for Distal Humerus Fractures

Feb 15th, 2022 - Heterotopic ossification is the formation of ectopic lamellar bone in the soft tissues. The process is thought to occur through local and distal recruitment osteoprogenitor cells especially mesenchymal stem cells which lead to HO formation based o...

Efficacy of Multimodal Analgesia Following Hip Arthroscopy

Oct 15th, 2021 - This pilot study will be a randomized controlled trial, where the surgical team, data collector, and patient will be blinded to the treatment received. The investigators will include any patient between the ages of 18 and 60 years undergoing hip a...

Multimodal Analgesia With Acetaminophen vs. Narcotics Alone After Hip Arthroscopy

Jan 7th, 2021 - The purpose of this proposed study is to evaluate the efficacy of a multimodal approach to analgesia for patient's pain after hip arthroscopy and to also assess if this new approach will result in a reduction in post-operative narcotic use. This s...

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News  12 results

Magnetic Resonance Imaging Evaluation of the Distal Biceps Tendon
Darren Fitzpatrick, MD, Leo Menashe, MD

May 23rd, 2018 - Partial distal bicep tears are characterized on MRI by focal or partial detachment of the tendon at the radial tuberosity with fluid filling the site of the tear. The degree of partial tearing can be assessed on MRI (Figures 5A, 5B).

Pseudo-Pedicle Heterotopic Ossification From Use of Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) in Transforaminal Lumbar Interbody Fusion Cages

Jan 29th, 2018 - Bone formation with rhBMP-2 is robust and beneficial, but HO-related complications are significant, and identifiable on assessment of radiculopathy symptoms and CT characteristics. DISCUSSION We identified 38 patients with a recognizable and consi.

Painful, Persistent Swelling Restricting Range of Motion in a Child

Sep 28th, 2016 - An early finding in patients with FOP is stiffness of the neck due to associated anomalies of the cervical spine. This can precede the appearance of heterotopic ossification at that site. Deformity of the great toes, such as shortened toes and hal...

Treatment of Acetabular Fractures in Adolescents

Sep 24th, 2015 - Minor complications (eg, meralgia paresthetica) resolved spontaneously. The most common complications were abductor weakness and heterotopic ossification.

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