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FDA Approves Botox® (Onabotulinumtoxina) For Pediatric Patients With Lower Limb Spasticity, Excluding Spasticity Caused By Cerebral Palsy
https://www.allergan.com/News/Details/2019/10/FDA%20Approves%20BOTOX%20onabotulinumtoxinA%20for%20Pediatric%20Patients%20with%20Lower%20Limb%20Spasticity%20Excluding%20Sp

Oct 23rd, 2019 - Allergan plc (NYSE: AGN) today announced that the U.S. Food and Drug Administration (FDA) approved the company's supplemental Biologics License Application (sBLA) for BOTOX® for the treatment of pediatric patients (2 to 17 years of age) with lower limb spasticity, excluding spasticity caused by cerebral palsy (CP). This marks the 11th BOTOX® therapeutic indication, having been approved for pedi...

WHO recommends dolutegravir as preferred HIV treatment option in all populations
https://www.who.int/news-room/detail/22-07-2019-who-recommends-dolutegravir-as-preferred-hiv-treatment-option-in-all-populations

Jul 21st, 2019 - Based on new evidence assessing benefits and risks, the WHO recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potential. Initial studies had highlighted a possible link between DTG and neural tube defects (birth defects of the brain and spinal cord that cause co...

Acupuncture for Pain
https://www.aafp.org/afp/2019/0715/p89.html
American Family Physician; Kelly, R. et. al.

Jul 14th, 2019 - Acupuncture has been increasingly used as an integrative or complementary therapy for pain. It is well-tolerated with little risk of serious adverse effects. Traditional acupuncture and nontraditional techniques, such as electroacupuncture and dry needling, often result in reported pain improvement. Multiple factors may contribute to variability in acupuncture's therapeutic effects, including n...

Arthritis Prevalence Statistics
https://www.rheumatology.org/Learning-Center/Statistics/Prevalence-Statistics

Jun 26th, 2019 - View overall prevalence of arthritis and rheumatic diseases as well as prevalence among specific racial and ethnic groups.

Spinal Stenosis And Neurogenic Claudication - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK430872/
Munakomi, S. et. al.

Jun 3rd, 2019 - Approximately 90% of the population will present with low back pain at some point in their lifetime. Spinal stenosis is a condition that is caused by the narrowing of the central canal, the lateral recess, or neural foramen. This is a condition that can cause significant discomfort, interfere with activities of daily living, and may result in progressive disability.With increasing longevity of...

Home-Based Cardiac Rehabilitation: A Scientific Statement From the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of C...
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000663
Thomas, R. et. al.

May 11th, 2019 - Cardiac rehabilitation (CR) is an evidence-based intervention that uses patient education, health behavior modification, and exercise training to improve secondary prevention outcomes in patients with cardiovascular disease. CR programs reduce morbidity and mortality rates in adults with ischemic heart disease, heart failure, or cardiac surgery but are significantly underused, with only a minor...

DEET | US EPA
https://www.epa.gov/insect-repellents/deet

May 8th, 2019 - Safety Review of DEET (chemical name, N,N-diethyl-meta-toluamide) is the active ingredient in many repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, an estimated one-third of the U.S. population use DEET to protect them from mosquito-borne illnesses like West Nile Virus, the Zika virus or malaria and tick-borne illnesses like Lyme disease and ...

Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000679

Apr 14th, 2019 - Cardiovascular disease is a competing cause of death in patients with cancer with early-stage disease. This elevated cardiovascular disease risk is thought to derive from both the direct effects of cancer therapies and the accumulation of risk factors such as hypertension, weight gain, cigarette smoking, and loss of cardiorespiratory fitness. Effective and viable strategies are needed to ...

Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline
http://www.bmj.com/lookup/doi/10.1136/bmj.l294
Vandvik, P.,et al

Feb 5th, 2019 - Clinical question: Do adults with atraumatic shoulder pain for more than 3 months diagnosed as subacromial pain syndrome (SAPS), also labelled as rotator cuff disease, benefit from subacromial decompression surgery? This guideline builds on to two recent high quality trials of shoulder surgery. Current practice: SAPS is the common diagnosis for shoulder pain with several first line treatment op.

International Stroke Conference 2019 Final Program
https://professional.heart.org/idc/groups/ahamah-public/@wcm/@sop/@scon/documents/downloadable/ucm_503240.pdf

Feb 4th, 2019 - The International Stroke Conference 2019 provides unique opportunities to meet and network with colleagues from around the world with wide-ranging research interests and expertise in stroke prevention, diagnosis, treatment and rehabilitation. For 2019, we anticipate more than 4,500 professional attendees, as well as exhibitors displaying exciting new stroke products and services. We are truly d...

Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2722564
Stein, M. et. al.

Jan 29th, 2019 - Question Who is at greatest risk for developing mental health problems such as posttraumatic stress disorder (PTSD) or major depression after sustaining a mild traumatic brain injury (mTBI)? Findings In this cohort study of 1155 patients with mTBI and 230 patients with orthopedic injuries not involving the head, patients with mTBI were more likely to report PTSD and/or major depressive sympto...

Intra-articular corticosteroids and the risk of knee osteoarthritis progression: results from the Osteoarthritis Initiative
https://www.oarsijournal.com/article/S1063-4584(19)30033-0/fulltext
Zeng, C. et. al.

Jan 27th, 2019 - Objective A recent randomized clinical trial reported that repeated intra-articular corticosteroids (IACs) were associated with a greater cartilage loss. This study aimed to examine the relation of IACs to knee radiographic osteoarthritis (ROA) progression in a real-world setting. Design A cohort that initiated IACs and a comparison cohort without IACs from participants with mild to moderate kn...

Teratology Society position statement on surveillance and prevalence estimation of neural tu...
https://onlinelibrary.wiley.com/doi/full/10.1002/bdr2.1434
Kancherla, V.,et al

Dec 18th, 2018 - In this position statement, the Teratology Society acknowledges the value of accurate measurement of total prevalence of neural tube defects (NTDs) in the population to support prevention, and advocates for rigorous surveillance world‐wide. NTDs, include anencephaly and spina bifida and are some of the more common types of structural birth defects affecting pregnancies worldwide.

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart ...
https://www.ahajournals.org/doi/abs/10.1161/ATV.0000000000000073
Newman, C.

Dec 9th, 2018 - One in 4 Americans >40 years of age takes a statin to reduce the risk of myocardial infarction, ischemic stroke, and other complications of atherosclerotic disease. The most effective statins produce a mean reduction in low-density lipoprotein cholesterol of 55% to 60% at the maximum dosage, and 6 of the 7 marketed statins are available in generic form, which makes them affordable for most pati.

Management Of Acute Compartment Syndrome
https://www.aaos.org/uploadedFiles/PreProduction/Quality/Guidelines_and_Reviews/guidelines/ACSguideline.pdf
Major Extremity Trauma and Rehabilitation Consortium

Dec 6th, 2018 - This clinical practice guideline is based on a formal systematic review of published studies with regard to the management of acute compartment syndrome of the upper or lower extremity in adults. In addition to providing clinical practice recommendations, this guideline also highlights limitations of the current literature and areas that require future research.

Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update
https://effectivehealthcare.ahrq.gov/sites/default/files/pdf/cer-214-stroke-a-fib-report.pdf

Sep 30th, 2018 - This systematic review is an update of an earlier report published in 2013 which evaluated questions related to stroke prevention in patients with atrial fibrillation (AF) and atrial flutter. Given evidence that has emerged since the publication of the 2013 report, this review focuses on updating and expanding the earlier work in three key areas: (1) evaluating the accuracy and utility of c...

Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild...
https://jamanetwork.com/journals/jamapediatrics/fullarticle/2698456
Lumba-Brown, A.

Sep 3rd, 2018 - Clinical guidance for health care professionals is critical to improving health and safety of this vulnerable population, the recommendations represent current best practices and comprise the first evidence-based clinical guideline to date for diagnosing and managing pediatric mTBI in the United States.

The 2018 ISDE achalasia guidelines
https://academic.oup.com/dote/article/31/9/doy071/5087687
Zaninotto, G.,et al.

Aug 31st, 2018 - Achalasia is a relatively rare primary motor esophageal disorder, characterized by absence of relaxations of the lower esophageal sphincter and of peristalsis along the esophageal body. As a result, patients typically present with dysphagia, regurgitation and occasionally chest pain, pulmonary complication and malnutrition.

Cardiac Rehabilitation Change Package
https://millionhearts.hhs.gov/files/Cardiac_Rehab_Change_Pkg.pdf
CDC

Aug 26th, 2018 - Cardiac rehabilitation (CR) is a comprehensive secondary prevention program designed to improve cardiovascular health following a cardiac-related event or procedure. While there are some instances of inpatient (Phase 1) CR, the vast majority of CR is delivered in an outpatient (Phase 2) setting and, therefore, is the focus of this publication.

Behavioral Therapy Approaches for the Management of Low Back Pain: An Up-To-Date Systematic Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993685/
Pain and Therapy; Vitoula, K. et. al.

May 15th, 2018 - Low back pain is one of the most common causes for seeking medical treatment and it is estimated that one in two people will experience low back pain at some point during their lifetimes. Management of low back pain includes pharmacological and non-pharmacological approaches. Non-pharmaceutical treatments include interventions such as acupuncture, spinal manipulation, and psychotherapy. The lat...

Female Athlete Issues for the Team Physician: A Consensus Statement
http://www.sportsmed.org/AOSSMIMIS/members/downloads/education/ConsensusStatements/FemaleAthlete.pdf
Stanley A. Herring

May 8th, 2018 - This document provides an overview of select musculoskeletal and medical issues that are important to team physicians who are responsible for the medical care of female athletes. It is not intended as a standard of care, and should not be interpreted as such.

2018 ACC/AHA Clinical Performance and Quality Measures for Cardiac Rehabilitation: A Report ...
https://www.ahajournals.org/doi/10.1161/HCQ.0000000000000037
Thomas, R

Mar 28th, 2018 - The American College of Cardiology (ACC)/American Heart Association (AHA) performance measurement sets serve as vehicles to accelerate translation of scientific evidence into clinical practice. Measure sets developed by the ACC/AHA are intended to provide practitioners and institutions that deliver cardiovascular services with tools to measure the quality of care provided and identify opportuni.

New Treatment Guidelines for Sjögren's Syndrome
https://www.sjogrens.org/files/research/RheumatologyCPG.pdf

Feb 13th, 2018 - Among all the chronic autoimmune rheumatic disorders, Sjo¨ gren’s disease (SD) is among the most difficult to evaluate and manage. Clinicians are frequently challenged to differentiate symptoms related to disease activity from those that result from preexisting damage. Additionally, the presence of multiple SD-related comorbidities, including anxiety, depression and fibromyalgia,1,2 may infl...

Fully Fund TBI Programs by Coordinating Federal Resources: BIAUSA Guideline
https://www.biausa.org/public-affairs/public-policy/fully-fund-tbi-programs
Brain Injury Association of America (BIAUSA)

Jan 31st, 2018 - BIAUSA recommends supporting HHS in carrying out its mandate to develop a plan for coordinating Federal activities impacting TBI service delivery, increase funding for TBI.

Increase Access to Care: BIAUSA Guideline
https://www.biausa.org/public-affairs/public-policy/increase-access-to-care
Brain Injury Association of America (BIAUSA)

Jan 31st, 2018 - BIAUSA recommends increasing access to care for individuals with brain injury.

Expand the Congressional Brain Injury Task Force: BIAUSA Guideline
https://www.biausa.org/public-affairs/public-policy/expand-the-congressional-brain-injury-task-force
Brain Injury Association of America (BIAUSA)

Jan 31st, 2018 - BIAUSA recommends expanding the Congressional Brain Injury Task Force.

Adult Dysphagia
https://www.asha.org/Practice-Portal/Clinical-Topics/Adult-Dysphagia/
American Speech-Language-Hearing Association

Dec 31st, 2017 - Speech-language pathologists (SLPs) with appropriate training and competence are involved in the diagnosis and management of oral and pharyngeal dysphagia. SLPs also recognize causes and signs/symptoms of esophageal dysphagia and make appropriate referrals for its diagnosis and management.

Childhood and Adolescent Adversity and Cardiometabolic Outcomes: A Scientific Statement From...
http://circ.ahajournals.org/content/early/2017/12/15/CIR.0000000000000536
Shakira F. Suglia

Dec 17th, 2017 - Adverse experiences in childhood and adolescence, defined as subjectively perceived threats to the safety or security of the child’s bodily integrity, family, or social structures, are known to be associated with cardiometabolic outcomes over the life course into adulthood. This American Heart Association scientific statement reviews the scientific literature on the influence of childhood adver.

Responses to Key Questions for Washington State Health Care Authority Health Technology Asse...
http://www.aans.org/-/media/Files/AANS/Advocacy/PDFS/Multispecialty-Society-Reponse-to-WA-HCA-HTA-Draft-Key-Questions-for-Lumbar-Radiculopathy-112717-FIN.ashx?la=en&hash=10C8E7BCB5ADFF377AC3DEF4666D95A5802C12A3
American Association of Neurological Surgeons

Nov 26th, 2017 - Lumbar radiculopathy is caused by nerve root compression in the lumbar spine. Symptoms include neuropathic pain, sensory dysfunction, and motor deficits.

Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Isc...
http://stroke.ahajournals.org/content/48/12/e343
Shadi Yaghi

Nov 1st, 2017 - Symptomatic intracranial hemorrhage (sICH) is the most feared complication of intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on expert opinion and small case series, with the efficacy of such treatments not well established.

Improving Medicare Post–Acute Care Transformation Act (IMPACT Act)?: BIAUSA Guideline
https://www.biausa.org/public-affairs/public-policy/improving-medicare-post-acute-care-transformation-act-impact-act
Brain Injury Association of America (BIAUSA)

Sep 30th, 2017 - The Improving Medicare Post-Acute Care Transformation Act of 2014 (HR 4994), commonly called the IMPACT Act, was signed by President Barack Obama as Public Law 113-185 on October 6, 2014. The legislation was designed to create a standardized platform to assess the efficacy of the treatment methods, quality measures, and health outcomes achieved by post-acute care (PAC) providers.

Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits
https://www.cghjournal.org/article/S1542-3565(17)30589-X/fulltext?code=yjcgh-site
Michael Camilleri, Anthony Lembo et. al.

Sep 29th, 2017 - The use of opioid medications on both an acute and chronic basis is ubiquitous in the United States. As opioid receptors densely populate the gastrointestinal tract, symptoms and side effects can be expected in these patients.

Protect the Affordable Care Act: BIAUSA Guideline
https://www.biausa.org/public-affairs/public-policy/protect-the-affordable-care-act
Brain Injury Association of America (BIAUSA)

Jul 31st, 2017 - Since the beginning of the 115th Congress, there has been significant attention focused on the repeal and replacement of the Affordable Care Act. The following is a summary of key developments.

ACR Appropriateness Criteria Cerebrovascular Disease
https://www.jacr.org/article/S1546-1440(17)30210-7/fulltext
Salmela, M.

Apr 30th, 2017 - Diseases of the cerebral vasculature represent a heterogeneous group of ischemic and hemorrhagic etiologies, which often manifest clinically as an acute neurologic deficit also known as stroke or less commonly with symptoms such as headache or seizures. Stroke is the fourth leading cause of death and is a leading cause of serious long-term disability in the United States.

ACR Appropriateness Criteria Stress (Fatigue/Insufficiency) Fracture, Including Sacrum, Excl...
https://www.jacr.org/article/S1546-1440(17)30218-1/fulltext
Bencardino, J.

Apr 30th, 2017 - Stress fractures, including both fatigue and insufficiency types, are frequently encountered in clinical practice as a source of pain in both athletes and patients with predisposing conditions. Radiography is the imaging modality of choice for baseline diagnosis.

Special Needs Trust Fairness Act: BIAUSA Guideline
https://www.biausa.org/public-affairs/public-policy/special-needs-trust-fairness-act
Brain Injury Association of America (BIAUSA)

Nov 30th, 2016 - The Special Needs Trust Fairness Act amends Title XIX of the Social Security Act to allow individuals with disabilities to establish their own special needs trusts. Formerly such trusts could only be established by parents, grandparents, legal guardians, or a court.

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medica...
https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/statin-use-in-adults-preventive-medication1
US Preventive Services Task Force

Oct 31st, 2016 - The USPSTF recommends that adults without a history of cardiovascular disease (CVD) (ie, symptomatic coronary artery disease or ischemic stroke) use a low- to moderate-dose statin for the prevention of CVD events and mortality when all of the following criteria are met: 1) they are aged 40 to 75 years, 2) they have 1 or more CVD risk factors (ie, dyslipidemia, diabetes, hypertension, or smoking.

Guidelines for Adult Stroke Rehabilitation and Recovery
http://www.aapmr.org/docs/default-source/advocacy/guidelines-for-adult-stroke-rehab.pdf
Carolee J. Winstein

May 11th, 2016 - Stroke rehabilitation requires a sustained and coordinated effort from a large team, including the patient and his or her goals, family and friends, other caregivers (eg, personal care attendants), physicians, nurses, physical and occupational therapists, speech-language pathologists, recreation therapists, psychologists, nutritionists, social workers, and others. Communication and coordination.

MANAGEMENT OF CARPAL TUNNEL SYNDROME: EVIDENCE-BASED CLINICAL PRACTICE GUIDELINE
https://www.aaos.org/uploadedFiles/PreProduction/Quality/Guidelines_and_Reviews/guidelines/CTS%20CPG_4.13.2017.pdf

Feb 28th, 2016 - The following is a summary of the recommendations of the AAOS Clinical Practice Guideline on the Management of Carpal Tunnel Syndrome.

MDA U.S. Neuromuscular Disease Registry
https://www.mda.org/services/neuromuscular-disease-registry
Muscular Dystrophy Association (USA)

Dec 31st, 2015 - In 2013, MDA launched the U. S.

Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation
http://www.thoracic.org/statements/resources/copd/implem-pulm-rehab.pdf
Carolyn L. Rochester

Nov 30th, 2015 - The ATS and ERS commit to undertake actions that will improve access to and delivery of PR services for suitable patients. They call on their members and other health professional societies, payers, patients, and patient advocacy groups to join in this commitment.

AAA Position on Embryo Manipulation: Guideline
https://www.anatomy.org/uploads/4/6/5/1/46517773/aaa-position-on-embryo-manipulation.pdf
American Association of Anatomists

May 26th, 2015 - letter describing position of American Association of Anatomists on embryo manipulation.

DEET (N,N-diethyl-meta-toluamide) - ATSDR
https://www.atsdr.cdc.gov/phs/phs.asp?id=1447&tid=201

Jan 20th, 2015 - DEET is the chemical N,N-diethyl-meta-toluamide. DEET is the active ingredient in some common repellents widely used to repel biting pests such as mosquitos and ticks. A significant benefit of DEET is protection against mosquito or tick borne illnesses such as West Nile Virus and Lyme disease. Occupational Safety and Health Administration (OSHA)

An Official American Thoracic Society Clinical Practice Guideline: The Diagnosis of Intensiv...
http://www.thoracic.org/statements/resources/cc/ICUAW_cpg.pdf
Eddy Fan

Dec 14th, 2014 - Research that identifies treatments that benefit patients with ICUAW is necessary to determine whether the benefits of diagnostic testing for ICUAW outweigh its burdens.

Paget's Disease of Bone: An Endocrine Society Clinical Practice Guideline
https://academic.oup.com/jcem/article/99/12/4408/2833929
Frederick R. Singer

Nov 30th, 2014 - We recommend that plain radiographs be obtained of the pertinent regions of the skeleton in patients with suspected Paget's disease. If the diagnosis is confirmed, we suggest that a radionucleotide bone scan be done to determine the extent of the disease.

Quality indicators for EGD
https://www.asge.org/docs/default-source/education/practice_guidelines/doc-b68366e5-03fd-429d-8150-77193bec8873.pdf?sfvrsn=6
Walter G. Park

Nov 30th, 2014 - EGD is used widely for the diagnosis and treatment of esophageal, gastric, and small-bowel disorders. When properly performed, it is generally safe and well-tolerated for the examination of the upper GI tract.

MANAGEMENT OF ANTERIOR CRUCIATE LIGAMENT INJURIES: EVIDENCE- BASED CLINICAL PRACTICE GUIDELINE
https://www.aaos.org/research/guidelines/ACLGuidelineFINAL.pdf

Sep 4th, 2014 - The following is a summary of the recommendations of the AAOS clinical practice guideline on the Management of Anterior Cruciate Ligament Injuries.

Four Strategies for Managing Opioid-Induced Side Effects in Older Adults
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418642/
Rogers, E. et. al.

Apr 4th, 2014 - Opioid medications are considered key therapeutic interventions in the management of both acute pain and cancer-related pain among patients of all ages; however, their role in treating patients with chronic noncancer pain remains controversial. While the debate about the appropriate role of opioids in the treatment of chronic pain continues, the fact remains that many clinicians prescribe opioi...

The role of endoscopy in the evaluation and management of dysphagia
https://www.asge.org/docs/default-source/education/practice_guidelines/doc-3c0fc1c6-37ac-4906-9301-74f813979375.pdf?sfvrsn=6
Shabana F. Pasha

Dec 12th, 2013 - Endoscopy is indicated in patients with dysphagia to determine the underlying etiology, exclude malignant and premalignant conditions, assess the need for therapy, and perform therapy, such as dilation. Esophageal dilation is a therapeutic procedure performed for the management of dysphagia.

Key Concepts and Advances in Pulmonary Rehabilitation
http://www.thoracic.org/statements/resources/copd/PRStatementrccm-2E201309-1634st.pdf
Martijn A. Spruit

Oct 14th, 2013 - The considerable growth in the science and application of pulmonary rehabilitation since 2006 adds further support for its efficacy in a wide range of individuals with chronic respiratory disease.