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About 131,318 results
FDA Approves Botox® (Onabotulinumtoxina) For Pediatric Patients With Lower Limb Spasticity, Excluding Spasticity Caused By Cerebral Palsy
https://www.allergan.com/News/Details/2019/10/FDA%20Approves%20BOTOX%20onabotulinumtoxinA%20for%20Pediatric%20Patients%20with%20Lower%20Limb%20Spasticity%20Excluding%20Sp

Oct 23rd, 2019 - Allergan plc (NYSE: AGN) today announced that the U.S. Food and Drug Administration (FDA) approved the company's supplemental Biologics License Application (sBLA) for BOTOX® for the treatment of pediatric patients (2 to 17 years of age) with lower limb spasticity, excluding spasticity caused by cerebral palsy (CP). This marks the 11th BOTOX® therapeutic indication, having been approved for pedi...

FDA approves first generics of Lyrica
https://www.fda.gov/news-events/press-announcements/fda-approves-first-generics-lyrica

Jul 21st, 2019 - On July 19, the U.S. Food and Drug Administration approved multiple applications for first generics of Lyrica (pregabalin) for the management of neuropathic pain associated with diabetic peripheral neuropathy, for the management of postherpetic neuralgia, as an adjunctive therapy for the treatment of partial onset seizures in patients 17 years of age and older, for the management of fibromyalgi...

WHO recommends dolutegravir as preferred HIV treatment option in all populations
https://www.who.int/news-room/detail/22-07-2019-who-recommends-dolutegravir-as-preferred-hiv-treatment-option-in-all-populations

Jul 21st, 2019 - Based on new evidence assessing benefits and risks, the WHO recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potential. Initial studies had highlighted a possible link between DTG and neural tube defects (birth defects of the brain and spinal cord that cause co...

Acupuncture for Pain
https://www.aafp.org/afp/2019/0715/p89.html
American Family Physician; Kelly, R. et. al.

Jul 14th, 2019 - Acupuncture has been increasingly used as an integrative or complementary therapy for pain. It is well-tolerated with little risk of serious adverse effects. Traditional acupuncture and nontraditional techniques, such as electroacupuncture and dry needling, often result in reported pain improvement. Multiple factors may contribute to variability in acupuncture's therapeutic effects, including n...

Arthritis Prevalence Statistics
https://www.rheumatology.org/Learning-Center/Statistics/Prevalence-Statistics

Jun 26th, 2019 - View overall prevalence of arthritis and rheumatic diseases as well as prevalence among specific racial and ethnic groups.

Spinal Stenosis And Neurogenic Claudication - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK430872/
Munakomi, S. et. al.

Jun 3rd, 2019 - Approximately 90% of the population will present with low back pain at some point in their lifetime. Spinal stenosis is a condition that is caused by the narrowing of the central canal, the lateral recess, or neural foramen. This is a condition that can cause significant discomfort, interfere with activities of daily living, and may result in progressive disability.With increasing longevity of...

Home-Based Cardiac Rehabilitation: A Scientific Statement From the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of C...
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000663
Thomas, R. et. al.

May 11th, 2019 - Cardiac rehabilitation (CR) is an evidence-based intervention that uses patient education, health behavior modification, and exercise training to improve secondary prevention outcomes in patients with cardiovascular disease. CR programs reduce morbidity and mortality rates in adults with ischemic heart disease, heart failure, or cardiac surgery but are significantly underused, with only a minor...

DEET | US EPA
https://www.epa.gov/insect-repellents/deet

May 8th, 2019 - Safety Review of DEET (chemical name, N,N-diethyl-meta-toluamide) is the active ingredient in many repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, an estimated one-third of the U.S. population use DEET to protect them from mosquito-borne illnesses like West Nile Virus, the Zika virus or malaria and tick-borne illnesses like Lyme disease and ...

Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000679

Apr 14th, 2019 - Cardiovascular disease is a competing cause of death in patients with cancer with early-stage disease. This elevated cardiovascular disease risk is thought to derive from both the direct effects of cancer therapies and the accumulation of risk factors such as hypertension, weight gain, cigarette smoking, and loss of cardiorespiratory fitness. Effective and viable strategies are needed to ...

Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline
http://www.bmj.com/lookup/doi/10.1136/bmj.l294
Vandvik, P.,et al

Feb 5th, 2019 - Clinical question: Do adults with atraumatic shoulder pain for more than 3 months diagnosed as subacromial pain syndrome (SAPS), also labelled as rotator cuff disease, benefit from subacromial decompression surgery? This guideline builds on to two recent high quality trials of shoulder surgery. Current practice: SAPS is the common diagnosis for shoulder pain with several first line treatment op.

International Stroke Conference 2019 Final Program
https://professional.heart.org/idc/groups/ahamah-public/@wcm/@sop/@scon/documents/downloadable/ucm_503240.pdf

Feb 4th, 2019 - The International Stroke Conference 2019 provides unique opportunities to meet and network with colleagues from around the world with wide-ranging research interests and expertise in stroke prevention, diagnosis, treatment and rehabilitation. For 2019, we anticipate more than 4,500 professional attendees, as well as exhibitors displaying exciting new stroke products and services. We are truly d...

Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2722564
Stein, M. et. al.

Jan 29th, 2019 - Question Who is at greatest risk for developing mental health problems such as posttraumatic stress disorder (PTSD) or major depression after sustaining a mild traumatic brain injury (mTBI)? Findings In this cohort study of 1155 patients with mTBI and 230 patients with orthopedic injuries not involving the head, patients with mTBI were more likely to report PTSD and/or major depressive sympto...

Intra-articular corticosteroids and the risk of knee osteoarthritis progression: results from the Osteoarthritis Initiative
https://www.oarsijournal.com/article/S1063-4584(19)30033-0/fulltext
Zeng, C. et. al.

Jan 27th, 2019 - Objective A recent randomized clinical trial reported that repeated intra-articular corticosteroids (IACs) were associated with a greater cartilage loss. This study aimed to examine the relation of IACs to knee radiographic osteoarthritis (ROA) progression in a real-world setting. Design A cohort that initiated IACs and a comparison cohort without IACs from participants with mild to moderate kn...

Teratology Society position statement on surveillance and prevalence estimation of neural tu...
https://onlinelibrary.wiley.com/doi/full/10.1002/bdr2.1434
Kancherla, V.,et al

Dec 18th, 2018 - In this position statement, the Teratology Society acknowledges the value of accurate measurement of total prevalence of neural tube defects (NTDs) in the population to support prevention, and advocates for rigorous surveillance world‐wide. NTDs, include anencephaly and spina bifida and are some of the more common types of structural birth defects affecting pregnancies worldwide.

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart ...
https://www.ahajournals.org/doi/abs/10.1161/ATV.0000000000000073
Newman, C.

Dec 9th, 2018 - One in 4 Americans >40 years of age takes a statin to reduce the risk of myocardial infarction, ischemic stroke, and other complications of atherosclerotic disease. The most effective statins produce a mean reduction in low-density lipoprotein cholesterol of 55% to 60% at the maximum dosage, and 6 of the 7 marketed statins are available in generic form, which makes them affordable for most pati.

Management Of Acute Compartment Syndrome
https://www.aaos.org/uploadedFiles/PreProduction/Quality/Guidelines_and_Reviews/guidelines/ACSguideline.pdf
Major Extremity Trauma and Rehabilitation Consortium

Dec 6th, 2018 - This clinical practice guideline is based on a formal systematic review of published studies with regard to the management of acute compartment syndrome of the upper or lower extremity in adults. In addition to providing clinical practice recommendations, this guideline also highlights limitations of the current literature and areas that require future research.

Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update
https://effectivehealthcare.ahrq.gov/sites/default/files/pdf/cer-214-stroke-a-fib-report.pdf

Sep 30th, 2018 - This systematic review is an update of an earlier report published in 2013 which evaluated questions related to stroke prevention in patients with atrial fibrillation (AF) and atrial flutter. Given evidence that has emerged since the publication of the 2013 report, this review focuses on updating and expanding the earlier work in three key areas: (1) evaluating the accuracy and utility of c...

Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild...
https://jamanetwork.com/journals/jamapediatrics/fullarticle/2698456
Lumba-Brown, A.

Sep 3rd, 2018 - Clinical guidance for health care professionals is critical to improving health and safety of this vulnerable population, the recommendations represent current best practices and comprise the first evidence-based clinical guideline to date for diagnosing and managing pediatric mTBI in the United States.

The 2018 ISDE achalasia guidelines
https://academic.oup.com/dote/article/31/9/doy071/5087687
Zaninotto, G.,et al.

Aug 31st, 2018 - Achalasia is a relatively rare primary motor esophageal disorder, characterized by absence of relaxations of the lower esophageal sphincter and of peristalsis along the esophageal body. As a result, patients typically present with dysphagia, regurgitation and occasionally chest pain, pulmonary complication and malnutrition.

Cardiac Rehabilitation Change Package
https://millionhearts.hhs.gov/files/Cardiac_Rehab_Change_Pkg.pdf
CDC

Aug 26th, 2018 - Cardiac rehabilitation (CR) is a comprehensive secondary prevention program designed to improve cardiovascular health following a cardiac-related event or procedure. While there are some instances of inpatient (Phase 1) CR, the vast majority of CR is delivered in an outpatient (Phase 2) setting and, therefore, is the focus of this publication.