About 7,656 results
FDA Approves Botox® (Onabotulinumtoxina) For Pediatric Patients With Lower Limb Spasticity, Excluding Spasticity Caused By Cerebral Palsy

Oct 23rd, 2019 - Allergan plc (NYSE: AGN) today announced that the U.S. Food and Drug Administration (FDA) approved the company's supplemental Biologics License Application (sBLA) for BOTOX® for the treatment of pediatric patients (2 to 17 years of age) with lower limb spasticity, excluding spasticity caused by cerebral palsy (CP). This marks the 11th BOTOX® therapeutic indication, having been approved for pedi...

WHO recommends dolutegravir as preferred HIV treatment option in all populations

Jul 21st, 2019 - Based on new evidence assessing benefits and risks, the WHO recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potential. Initial studies had highlighted a possible link between DTG and neural tube defects (birth defects of the brain and spinal cord that cause co...

Acupuncture for Pain
American Family Physician; Kelly, R. et. al.

Jul 14th, 2019 - Acupuncture has been increasingly used as an integrative or complementary therapy for pain. It is well-tolerated with little risk of serious adverse effects. Traditional acupuncture and nontraditional techniques, such as electroacupuncture and dry needling, often result in reported pain improvement. Multiple factors may contribute to variability in acupuncture's therapeutic effects, including n...

Arthritis Prevalence Statistics

Jun 26th, 2019 - View overall prevalence of arthritis and rheumatic diseases as well as prevalence among specific racial and ethnic groups.

Spinal Stenosis And Neurogenic Claudication - StatPearls
Munakomi, S. et. al.

Jun 3rd, 2019 - Approximately 90% of the population will present with low back pain at some point in their lifetime. Spinal stenosis is a condition that is caused by the narrowing of the central canal, the lateral recess, or neural foramen. This is a condition that can cause significant discomfort, interfere with activities of daily living, and may result in progressive disability.With increasing longevity of...

Home-Based Cardiac Rehabilitation: A Scientific Statement From the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of C...
Thomas, R. et. al.

May 11th, 2019 - Cardiac rehabilitation (CR) is an evidence-based intervention that uses patient education, health behavior modification, and exercise training to improve secondary prevention outcomes in patients with cardiovascular disease. CR programs reduce morbidity and mortality rates in adults with ischemic heart disease, heart failure, or cardiac surgery but are significantly underused, with only a minor...


May 8th, 2019 - Safety Review of DEET (chemical name, N,N-diethyl-meta-toluamide) is the active ingredient in many repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, an estimated one-third of the U.S. population use DEET to protect them from mosquito-borne illnesses like West Nile Virus, the Zika virus or malaria and tick-borne illnesses like Lyme disease and ...

Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors

Apr 14th, 2019 - Cardiovascular disease is a competing cause of death in patients with cancer with early-stage disease. This elevated cardiovascular disease risk is thought to derive from both the direct effects of cancer therapies and the accumulation of risk factors such as hypertension, weight gain, cigarette smoking, and loss of cardiorespiratory fitness. Effective and viable strategies are needed to ...

International Stroke Conference 2019 Final Program

Feb 4th, 2019 - The International Stroke Conference 2019 provides unique opportunities to meet and network with colleagues from around the world with wide-ranging research interests and expertise in stroke prevention, diagnosis, treatment and rehabilitation. For 2019, we anticipate more than 4,500 professional attendees, as well as exhibitors displaying exciting new stroke products and services. We are truly d...

Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury
Stein, M. et. al.

Jan 29th, 2019 - Question Who is at greatest risk for developing mental health problems such as posttraumatic stress disorder (PTSD) or major depression after sustaining a mild traumatic brain injury (mTBI)? Findings In this cohort study of 1155 patients with mTBI and 230 patients with orthopedic injuries not involving the head, patients with mTBI were more likely to report PTSD and/or major depressive sympto...

Intra-articular corticosteroids and the risk of knee osteoarthritis progression: results from the Osteoarthritis Initiative
Zeng, C. et. al.

Jan 27th, 2019 - Objective A recent randomized clinical trial reported that repeated intra-articular corticosteroids (IACs) were associated with a greater cartilage loss. This study aimed to examine the relation of IACs to knee radiographic osteoarthritis (ROA) progression in a real-world setting. Design A cohort that initiated IACs and a comparison cohort without IACs from participants with mild to moderate kn...

Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update

Sep 30th, 2018 - This systematic review is an update of an earlier report published in 2013 which evaluated questions related to stroke prevention in patients with atrial fibrillation (AF) and atrial flutter. Given evidence that has emerged since the publication of the 2013 report, this review focuses on updating and expanding the earlier work in three key areas: (1) evaluating the accuracy and utility of c...

Behavioral Therapy Approaches for the Management of Low Back Pain: An Up-To-Date Systematic Review
Pain and Therapy; Vitoula, K. et. al.

May 15th, 2018 - Low back pain is one of the most common causes for seeking medical treatment and it is estimated that one in two people will experience low back pain at some point during their lifetimes. Management of low back pain includes pharmacological and non-pharmacological approaches. Non-pharmaceutical treatments include interventions such as acupuncture, spinal manipulation, and psychotherapy. The lat...

New Treatment Guidelines for Sjögren's Syndrome

Feb 13th, 2018 - Among all the chronic autoimmune rheumatic disorders, Sjo¨ gren’s disease (SD) is among the most difficult to evaluate and manage. Clinicians are frequently challenged to differentiate symptoms related to disease activity from those that result from preexisting damage. Additionally, the presence of multiple SD-related comorbidities, including anxiety, depression and fibromyalgia,1,2 may infl...

DEET (N,N-diethyl-meta-toluamide) - ATSDR

Jan 20th, 2015 - DEET is the chemical N,N-diethyl-meta-toluamide. DEET is the active ingredient in some common repellents widely used to repel biting pests such as mosquitos and ticks. A significant benefit of DEET is protection against mosquito or tick borne illnesses such as West Nile Virus and Lyme disease. Occupational Safety and Health Administration (OSHA)

Four Strategies for Managing Opioid-Induced Side Effects in Older Adults
Rogers, E. et. al.

Apr 4th, 2014 - Opioid medications are considered key therapeutic interventions in the management of both acute pain and cancer-related pain among patients of all ages; however, their role in treating patients with chronic noncancer pain remains controversial. While the debate about the appropriate role of opioids in the treatment of chronic pain continues, the fact remains that many clinicians prescribe opioi...

Preventing Overuse Injuries | Overuse Injury Diagnosis & Prevention | STOP Sports Injuries

Mar 27th, 2010 - How to prevent sports related overuse injuries. How to spot and prevent an overuse injury.

Refractory heartburn
Gastroenterology Kahrilas, P.

May 31st, 2003 - A 33-year-old woman presents to her primary care physician with a chief complaint of heartburn for the past 12 months. She describes this as a severe burning discomfort beneath the breastbone occurring throughout the day. The patient has no history of dysphagia, vomiting, weight loss, or gastrointestinal bleeding. She reports regurgitation once a month, unchanged in the recent past. Reasoning t...

New Head Injury Data Reinforce Restricted Antipsychotic Use in Dementia

Jan 15th, 2020 - Antipsychotic medications raise the risk of head injury and traumatic brain injury (TBI) in people with Alzheimer's disease (AD), new research shows. These new data support long-standing evidence-based clinical guidance to limit the use of antipsychotics in dementia patients to those with the most severe neuropsychiatric symptoms and for as short a time as possible. "Previous studies have shown...

RimabotulinumtoxinB Reduces Sialorrhea in Adults

Jan 15th, 2020 - NEW YORK (Reuters Health) - RimabotulinumtoxinB (RIMA) safely reduces sialorrhea in adults, according to results from the phase 3 MYSTICOL clinical trial. Sialorrhea, the excess spillage of saliva from the mouth, affects up to 74% of people with Parkinson's disease and up to half of patients with amyotrophic lateral sclerosis (ALS), and it is commonly seen in stroke survivors. Injection of botu...