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About 5,010 results

ALLMedicine™ Lumbar Puncture Center

Research & Reviews  1,622 results

Cerebrospinal Fluid Collection and Repository Storage
https://clinicaltrials.gov/ct2/show/NCT01862107

May 20th, 2022 - In this study we are planning to establish a repository of cerebrospinal fluid (CSF), serum, and plasma. We are planning to collect a small amount of additional CSF and blood on subjects who are already going to have a lumbar puncture as part of t...

Clinical and Laboratory Study of Methylmalonic Acidemia
https://clinicaltrials.gov/ct2/show/NCT00078078

May 20th, 2022 - Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations. Affected patients with cblA, cblB and mut classes of MMA are medically fragile and can suffer ...

Inflammatory and Infectious Diseases of the Nervous System
https://clinicaltrials.gov/ct2/show/NCT02435810

May 20th, 2022 - Objective: The objective of this study is to examine the natural course of infectious and inflammatory diseases of the nervous system, to identify causative or associated pathogens when unknown, and generally to better understand the underlying im...

Long-term open-label phase I/II extension study of intrathecal idursulfase-IT in the tr...
https://doi.org/10.1016/j.gim.2022.04.002
Genetics in Medicine : Official Journal of the American C... Muenzer J, Vijayaraghavan S et. al.

May 20th, 2022 - Intrathecal (IT) idursulfase-IT for the treatment of cognitive impairment is being investigated in pediatric patients with neuronopathic mucopolysaccharidosis II (MPS II) in addition to intravenous idursulfase. In this article, we report the findi...

Outcomes of children presenting to the emergency department with fever and bulging font...
https://doi.org/10.1016/j.ajem.2022.04.011
The American Journal of Emergency Medicine; Shahada J, Tavor O et. al.

May 20th, 2022 - In infants aged 3-18 months presenting with a bulging fontanelle and fever it is often necessary to exclude central nervous system infection by performing a lumbar puncture. Several studies have shown that well-appearing infants with normal clinic...

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Guidelines  6 results

Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical p...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364256
BMJ (Clinical Research Ed.); Rochwerg B, Almenawer SA et. al.

May 24th, 2018 - Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline.|2018|Rochwerg B,Almenawer SA,Siemieniuk RAC,Vandvik PO,Agoritsas T,|economics,economics,prevention & control,adverse effects,instrumentation,

European Stroke Organization guideline for the diagnosis and treatment of cerebral veno...
https://doi.org/10.1111/ene.13381
European Journal of Neurology; Ferro JM, Bousser MG et. al.

Aug 24th, 2017 - Current guidelines on cerebral venous thrombosis (CVT) diagnosis and management were issued by the European Federation of Neurological Societies in 2010. We aimed to update the previous European Federation of Neurological Societies guidelines usin...

The UK joint specialist societies guideline on the diagnosis and management of acute me...
https://doi.org/10.1016/j.jinf.2016.01.007
The Journal of Infection; McGill F, Heyderman RS et. al.

Feb 5th, 2016 - Bacterial meningitis and meningococcal sepsis are rare conditions with high case fatality rates. Early recognition and prompt treatment saves lives. In 1999 the British Infection Society produced a consensus statement for the management of immunoc...

Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Pa...
https://doi.org/10.3171/2014.7.PEDS14322
Journal of Neurosurgery. Pediatrics; Mazzola CA, Choudhri AF et. al.

May 20th, 2015 - The objective of this systematic review and analysis was to answer the following question: What are the optimal treatment strategies for posthemorrhagic hydrocephalus (PHH) in premature infants? Both the US National Library of Medicine and the Coc...

Platelet transfusion: a clinical practice guideline from the AABB.
https://doi.org/10.7326/M14-1589
Annals of Internal Medicine; Kaufman RM, Djulbegovic B et. al.

Nov 11th, 2014 - The AABB (formerly, the American Association of Blood Banks) developed this guideline on appropriate use of platelet transfusion in adult patients. These guidelines are based on a systematic review of randomized, clinical trials and observational ...

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Drugs  10 results see all →

Clinicaltrials.gov  145 results

Cerebrospinal Fluid Collection and Repository Storage
https://clinicaltrials.gov/ct2/show/NCT01862107

May 20th, 2022 - In this study we are planning to establish a repository of cerebrospinal fluid (CSF), serum, and plasma. We are planning to collect a small amount of additional CSF and blood on subjects who are already going to have a lumbar puncture as part of t...

Clinical and Laboratory Study of Methylmalonic Acidemia
https://clinicaltrials.gov/ct2/show/NCT00078078

May 20th, 2022 - Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations. Affected patients with cblA, cblB and mut classes of MMA are medically fragile and can suffer ...

Inflammatory and Infectious Diseases of the Nervous System
https://clinicaltrials.gov/ct2/show/NCT02435810

May 20th, 2022 - Objective: The objective of this study is to examine the natural course of infectious and inflammatory diseases of the nervous system, to identify causative or associated pathogens when unknown, and generally to better understand the underlying im...

Target Engagement of Terazosin in Healthy Adults
https://clinicaltrials.gov/ct2/show/NCT04551040

May 17th, 2022 - The study is a single center, 37-day, controlled pilot study to assess the target engagement of Terazosin (TZ) in a single cohort of 6 healthy adult participants (3 men and 3 women.) During the study participants will undergo PET/CT scans, 7-Tesla...

Enoxacin for Amyotrophic Lateral Sclerosis (ALS)
https://clinicaltrials.gov/ct2/show/NCT04840823

Apr 27th, 2022 - Participants will be randomized to one of three doses of enoxacin (200, 400, or 600mg twice daily) for 30 days. On day 1, 7, 14, 21, and 30 of treatment and at a follow-up visit 14 days after the last dose, participants will be assessed for safety...

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News  187 results

Tau Moderated by Menopause; CTE Risk Underestimated; When Is a Single Study Enough?
https://www.medpagetoday.com/neurology/generalneurology/98523

May 3rd, 2022 - Menopause status moderated sex differences in tau burden, with a divergence in tauopathy between the sexes apparent 20 years earlier than previously reported. (Annals of Neurology) Plasma p-tau was a less consistent marker of brain amyloidosis in ...

What’s the most likely cause of this man’s severe headaches?
https://www.mdedge.com/internalmedicine/article/253898/neurology/whats-most-likely-cause-mans-severe-headaches
Douglas S. Paauw, MD

Apr 19th, 2022 - A 35-year-old man comes to clinic for evaluation of new, severe headaches. He reports that these started 3 days ago.

More Evidence COVID 'Brain Fog' Is Biologically Based
https://www.medscape.com/viewarticle/971408

Apr 1st, 2022 - Patients with persistent cognitive impairment months after illness with mild COVID-19 have higher levels of inflammatory markers in their cerebrospinal fluid (CSF). Researchers found elevated levels of CSF immune activation and immunovascular mark...

Febrile Infants: When Can We Skip the Lumbar Puncture?
https://www.medscape.com/viewarticle/962507

Dec 8th, 2021 - This transcript has been edited for clarity. Christopher J. Chiu, MD: Welcome back to The Cribsiders and our Medscape video recap of our pediatric medicine podcast. Justin, what are we talking about today? Justin L. Berk, MD, MPH, MBA: We're talki...

Managing Simple Febrile Seizures Without Lumbar Puncture Safe: 15-Year Study
https://www.medscape.com/viewarticle/962096

Nov 2nd, 2021 - Most children with simple febrile seizures (SFSs) can be safely managed without lumbar puncture or other diagnostic tests without risking delayed diagnosis of bacterial meningitis, new data gathered from a 15-year span suggest. Vidya R. Raghavan, ...

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Patient Education  34 results see all →