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About 5,263 results

ALLMedicine™ Splenectomy Center

Research & Reviews  1,953 results

Blunt splenic injury in adults: Association between volumetric quantitative CT paramete...
https://doi.org/10.1097/TA.0000000000003684
The Journal of Trauma and Acute Care Surgery; Dreizin D, Champ K et. al.

May 14th, 2022 - Several ordinal grading systems are employed in deciding whether to perform angioembolization or splenectomy following blunt splenic injury. The 2018 AAST Organ Injury Scale (OIS) incorporates vascular lesions but not hemoperitoneum, which is cons...

High-affinity autoreactive plasma cells disseminate through multiple organs in patients...
https://doi.org/10.1172/JCI153580
The Journal of Clinical Investigation; Canales-Herrerias P, Crickx E et. al.

May 4th, 2022 - The major therapeutic goal for immune thrombocytopenia (ITP) is to restore normal platelet counts using drugs to promote platelet production or by interfering with mechanisms responsible for platelet destruction. 80% of patients possess anti-integ...

Partial splenectomy in children undergoing liver transplantation or venous shunt for se...
https://doi.org/10.1016/j.clinre.2022.101929
Clinics and Research in Hepatology and Gastroenterology; Boillot O, Chopinet S et. al.

Apr 25th, 2022 - Hypersplenism is a consequence of portal hypertension and splenomegaly secondary to cirrhosis or portal cavernoma in children. In order to avoid persistent hypersplenism and splenomegaly after liver transplantation (LT) or venous shunt (VS), parti...

Long-term Results of Splenectomy in Transfusion-dependent Thalassemia.
https://doi.org/10.1097/MPH.0000000000002468
Journal of Pediatric Hematology/oncology; Akca T, Ozdemir GN et. al.

Apr 22nd, 2022 - Splenectomy is indicated in transfusion-dependent thalassemia (TDT) only in certain situations. This study aimed to present the effectiveness, complications, and long-term follow-up results of splenectomy in children with TDT. We performed a 30-ye...

Effect of side guide marks of ultrasound transducer on the success rate of ultrasound t...
https://doi.org/10.1177/11297298221091415
The Journal of Vascular Access; Yao J, Hao S et. al.

Apr 21st, 2022 - Compared with blind technique, ultrasound (US) transducer-guided technique for radial artery puncture can improve the success rate. However, difficulty in handling US transducer-guided technology is a key limitation to its wider use. The aim of th...

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Guidelines  1 results

Laparoscopic splenectomy: the clinical practice guidelines of the European Association ...
https://doi.org/10.1007/s00464-007-9735-5
Surgical Endoscopy; Habermalz B, Sauerland S et. al.

Feb 23rd, 2008 - Although laparoscopic splenectomy (LS) has become the standard approach for most splenectomy cases, some areas still remain controversial. To date, the indications that preclude laparoscopic splenectomy are not clearly defined. In view of this, th...

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Drugs  2 results see all →

Clinicaltrials.gov  43 results

The Effect of Laparoscopic Splenectomy on the Immune Function for Cirrhosis Patients
https://clinicaltrials.gov/ct2/show/NCT05339269

Apr 21st, 2022 - The patients were enrolled according to the research criteria, and collected the general basic information of the patients. After the preoperative preparation was perfected, the same surgical team performed laparoscopic splenectomy, and the same n...

The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients
https://clinicaltrials.gov/ct2/show/NCT05325424

Apr 13th, 2022 - The patients were enrolled according to the research criteria, and collected the general basic information of the patients. After the preoperative preparation was perfected, the same surgical team performed laparoscopic splenectomy, and the same n...

Extended Dosing With Eltrombopag for Severe Aplastic Anemia
https://clinicaltrials.gov/ct2/show/NCT01891994

Apr 12th, 2022 - Severe aplastic anemia (SAA) is a life-threatening blood disease that can be successfully treated with immunosuppressive drug regimens or allogeneic stem cell transplantation. However, 20-40% of patients are ineligible for transplant due to lack o...

Laparoscopic Splenectomy and Azygoportal Disconnection With Intraoperative Endoscopic Variceal Ligation
https://clinicaltrials.gov/ct2/show/NCT04244487

Mar 21st, 2022 - After successful screening the cases of cirrhosis of liver irrespective of the etiology who have prior esophageal/gastroesophageal variceal bleeding will be enrolled. The baseline parameter will be recorded and the patient will be randomized into ...

The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT05004259

Mar 16th, 2022 - Autoimmune Hemolytic Anemia (AIHA) is a hematologic disorder in which the red blood cells are targeted and destroyed by autoantibodies produced by the immune system, specifically B-cells and plasma cells. It can be either idiopathic, or secondary ...

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News  100 results

ITP Armamentarium Expands With the Hope of Limiting Long-Term Steroid Exposure
https://www.onclive.com/view/itp-armamentarium-expands-with-the-hope-of-limiting-long-term-steroid-exposure

Apr 18th, 2022 - Although patients with primary and secondary immune thrombocytopenia (ITP) can derive good responses from corticosteroids, long-term exposure to steroids is associated with unique adverse effects (AEs), said Kanwarpal S. Kahlon, MD, who added that...

BTK Inhibitor Shows Potential in Immune Thrombocytopenia
https://www.medpagetoday.com/hematologyoncology/hematology/98188

Apr 13th, 2022 - An investigational oral Bruton's tyrosine kinase (BTK) inhibitor was tolerable and yielded rapid and durable responses in pretreated patients with immune thrombocytopenia (ITP), according to results of an open-label phase I/II trial. In the 60-pat...

Role of Splenectomy in Immune Thrombocytopenia Treatment
https://www.onclive.com/view/role-of-splenectomy-in-immune-thrombocytopenia-treatment

Feb 2nd, 2022 - James Bussel, MD: For this patient, who might be a young woman, Caroline outlined specifically why dexamethasone and rituximab may be good. We’ve been talking about the risks of vaccination, and I thought you’d bring up flu vaccines. The other thi...

FDA Grants Priority Review to Luspatercept-aamt for Non–Transfusion Dependent Beta Thalassemia
https://www.onclive.com/view/fda-grants-priority-review-to-luspatercept-aamt-for-non-transfusion-dependent-beta-thalassemia

Dec 3rd, 2021 - The FDA has granted priority review to the supplemental biologics license application (sBLA) for luspatercept-aamt (Reblozyl) for the treatment of anemia in adults with non–transfusion dependent (NTD) β-thalassemia. The European Medicines Agency h...

Hemophagocytic Lymphohistiocytosis: Early Treatment Leading to an Excellent Outcome
https://www.mdedge.com/fedprac/article/245877/hematologic-malignancies/hemophagocytic-lymphohistiocytosis-early-treatment
Gerald Marín-García, MD, José María-Rios, MD et. al.

Sep 9th, 2021 - Hemophagocytic lymphohistiocytosis (HLH) is a rare and deadly disease in which unregulated proliferation of histiocytes and T-cell infiltration takes place. It is known as a pediatric disease in which gene defects result in impaired cytotoxic NK-.

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Patient Education  6 results see all →