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About 14,981 results

ALLMedicine™ Antiepileptic Drugs Center

Research & Reviews  7,025 results

Association between ABCB1 polymorphisms and response to antiepileptic drugs among Jorda...
https://doi.org/10.1080/01616412.2021.1922182
Neurological Research; Tamimi DE, Abduljabbar R et. al.

May 5th, 2021 - Genetic polymorphisms of drug efflux transporters as ATP-binding cassette subfamily B, member 1 (ABCB1) have been suggested to modulate antiepileptic drugs (AEDs) response. We aimed to explore the association of ABCB1 polymorphisms and AEDs resist...

Efficacy of Phytocannabinoids in Epilepsy Treatment: Novel Approaches and Recent Advances.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070313
International Journal of Environmental Research and Publi... Farrelly AM, Vlachou S et. al.

Apr 30th, 2021 - Epilepsy is a neurological disorder mainly characterised by recurrent seizures that affect the entire population diagnosed with the condition. Currently, there is no cure for the disease and a significant proportion of patients have been deemed to...

Evaluating the protective effects of individual or combined ginsenoside compound K and ...
https://doi.org/10.1016/j.taap.2021.115555
Toxicology and Applied Pharmacology; Zhou L, Zeng X et. al.

Apr 29th, 2021 - Sodium valproate (SVP) is one of the most commonly prescribed antiepileptic drugs. However, SVP is known to induce hepatotoxicity, which limits its clinical application for treating various neurological disorders. Previously, we found that ginseno...

Examination of the antiepileptic effects of valacyclovir using kindling mice- Search fo...
https://doi.org/10.1016/j.ejphar.2021.174099
European Journal of Pharmacology; Takahashi S, Takechi K et. al.

Apr 28th, 2021 - Despite the availability of more than 20 clinical antiepileptic drugs, approximately 30% of patients with epilepsy do not respond to antiepileptic drug treatment. Therefore, it is important to develop antiepileptic products that function via novel...

Cymbopogon citratus (DC.) Stapf, citral and geraniol exhibit anticonvulsant and neuropr...
https://doi.org/10.1016/j.jep.2021.114142
Journal of Ethnopharmacology; Hacke ACM, Miyoshi E et. al.

Apr 28th, 2021 - Cymbopogon citratus (DC.) Stapf (C. citratus) is consumed as an infusion in folk medicine due to its pharmacological properties and action in the central nervous system. Epilepsy is a neurological disorder that affects millions of people. Since th...

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Guidelines  23 results

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003032.pub4/full
Brigo,F.,et al

Feb 7th, 2019 - Absence seizures (AS) are brief epileptic seizures which present in childhood and adolescence. Depending on clinical features and electroencephalogram (EEG) findings they are divided into typical, atypical absences, and absences with special featu...

Ketogenic diets for drug‐resistant epilepsy.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001903.pub4/full
The Cochrane Database of Systematic Reviews;

Nov 6th, 2018 - Ketogenic diets (KDs), being high in fat and low in carbohydrates, have been suggested to reduce seizure frequency in people with epilepsy. At present, such diets are mainly recommended for children who continue to have seizures despite treatment ...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs ...
http://n.neurology.org/content/91/2/74
Kanner, A.

Jul 9th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs).

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 14th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 14th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

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Drugs  27 results see all →

Clinicaltrials.gov  7,315 results

Association between ABCB1 polymorphisms and response to antiepileptic drugs among Jorda...
https://doi.org/10.1080/01616412.2021.1922182
Neurological Research; Tamimi DE, Abduljabbar R et. al.

May 5th, 2021 - Genetic polymorphisms of drug efflux transporters as ATP-binding cassette subfamily B, member 1 (ABCB1) have been suggested to modulate antiepileptic drugs (AEDs) response. We aimed to explore the association of ABCB1 polymorphisms and AEDs resist...

Efficacy of Phytocannabinoids in Epilepsy Treatment: Novel Approaches and Recent Advances.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070313
International Journal of Environmental Research and Publi... Farrelly AM, Vlachou S et. al.

Apr 30th, 2021 - Epilepsy is a neurological disorder mainly characterised by recurrent seizures that affect the entire population diagnosed with the condition. Currently, there is no cure for the disease and a significant proportion of patients have been deemed to...

Evaluating the protective effects of individual or combined ginsenoside compound K and ...
https://doi.org/10.1016/j.taap.2021.115555
Toxicology and Applied Pharmacology; Zhou L, Zeng X et. al.

Apr 29th, 2021 - Sodium valproate (SVP) is one of the most commonly prescribed antiepileptic drugs. However, SVP is known to induce hepatotoxicity, which limits its clinical application for treating various neurological disorders. Previously, we found that ginseno...

Examination of the antiepileptic effects of valacyclovir using kindling mice- Search fo...
https://doi.org/10.1016/j.ejphar.2021.174099
European Journal of Pharmacology; Takahashi S, Takechi K et. al.

Apr 28th, 2021 - Despite the availability of more than 20 clinical antiepileptic drugs, approximately 30% of patients with epilepsy do not respond to antiepileptic drug treatment. Therefore, it is important to develop antiepileptic products that function via novel...

Cymbopogon citratus (DC.) Stapf, citral and geraniol exhibit anticonvulsant and neuropr...
https://doi.org/10.1016/j.jep.2021.114142
Journal of Ethnopharmacology; Hacke ACM, Miyoshi E et. al.

Apr 28th, 2021 - Cymbopogon citratus (DC.) Stapf (C. citratus) is consumed as an infusion in folk medicine due to its pharmacological properties and action in the central nervous system. Epilepsy is a neurological disorder that affects millions of people. Since th...

see more →

News  591 results

Prenatal Dietary Folate Not Enough to Offset AEDs' Effect on Kids' Cognition
https://www.medscape.com/viewarticle/947829

Mar 21st, 2021 - New research underscores the importance of folic acid supplementation for pregnant women with epilepsy who are taking antiepileptic drugs (AEDs). Dietary folate alone, even in the United States, where food is fortified with folic acid, is "not suf...

More Reassurance for Certain Antiseizure Drugs in Pregnancy
https://www.medscape.com/viewarticle/947241

Mar 9th, 2021 - Further evidence supporting the safety of two antiseizure medications in pregnancy has come from a new study. The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study found no difference in neurobehavioral develop...

Choosing Contraception for Young Women With Seizure Disorders: New Guidance From ACOG
https://www.medscape.com/viewarticle/930698

Jun 8th, 2020 - This transcript has been edited for clarity. Ob/gyns and others who care for women often encounter teens and young women with seizure disorders. Many of these patients take antiepileptic drugs (AEDs). The American College of Obstetricians and Gyne...

Off to College: Safe to Stop His Antiepileptic Drug?
https://www.medscape.com/viewarticle/926980_2

Mar 22nd, 2020 - My Take on Deprescribing Antiepileptic Drugs Records from the patient's workup 5 years earlier and the last clinic note from neurology, dated 2 years earlier, are available. At that time, the neurologist recommended continuing his treatment. Befor...

Antiepileptic drugs may not independently impair cognition
https://www.mdedge.com/jcomjournal/article/217306/epilepsy-seizures/antiepileptic-drugs-may-not-independently-impair/page/0/1?channel=258

Feb 13th, 2020 - Approximately 45% of patients were prescribed AED polypharmacy on admission, 25. 1% were prescribed AED monotherapy, and 29.

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