ALLMedicine™ Antiretroviral Therapy Center

Aug 1st, 2021 - HIV-1 viral load (VL) testing is essential for monitoring the effects of antiretroviral therapy in HIV-infected patients. In order to identify factors that impact testing performance of HIV-1 VL testing laboratories, this study performed a retrosp...

Jul 31st, 2021 - Economic strengthening (ES) interventions can address economic barriers to retention and adherence (R&A) to antiretroviral therapy in prevention of mother-to-child transmission (PMTCT) services. To inform tailoring of ES activities for PMTCT, we u...

Jul 31st, 2021 - A screening centre in Soweto, South Africa (SA), investigated high-risk human papillomavirus (HR-HPV), HIV, cervical cancer risk amongst women. This cross-sectional study (June 2018-March 2019) describes screening results (Roche Linear Array HPV t...

Jul 31st, 2021 - We have previously shown that initiation of antiretroviral therapy (ART) is associated with a decrease in skeletal muscle density (greater fat accumulation), suggesting that gains in lean body mass seen in many ART studies may reflect gains in low...

Jul 31st, 2021 - The World Health Organization recommends that all countries adopt dolutegravir-based antiretroviral therapy as the preferred regimen for all individuals living with HIV. Levonorgestrel is a commonly used hormonal contraceptive, which undergoes dru...

Oct 15th, 2020 - Data on the use of antiretroviral drugs, including new drugs and formulations, for the treatment and prevention of HIV infection continue to guide optimal practices. To evaluate new data and incorporate them into current recommendations for initia...

Jan 4th, 2019 - Life expectancy of people living with HIV (PLWH) is reaching similar length as in the general population. Accordingly, age-related comorbidities, including osteoporosis, are increasing. Fracture risk is higher and increases approximately 10 years ...

Aug 23rd, 2018 - This Committee Opinion is being revised to provide updated guidance on the management of pregnant women during pregnancy and delivery to prevent mother-to-child transmission of the human immunodeficiency virus (HIV). Prevention of transmission of ...

Aug 23rd, 2018 - Given the enormous advances in the prevention of perinatal transmission of human immunodeficiency virus (HIV), it is clear that early identification and treatment of all pregnant women with HIV is the best way to prevent neonatal infection and als...

Aug 23rd, 2018 - This Committee Opinion is being revised to provide updated guidance on the management of pregnant women during pregnancy and delivery to prevent mother-to-child transmission of the human immunodeficiency virus (HIV). Prevention of transmission of ...

May 7th, 2020 - In an attempt to elucidate the mechanism(s) of immune-mediated restriction of HIV viral replication, we aim to study four groups of individuals: 1) HIV-infected long-term nonprogressors (LTNP), who appear to control HIV primarily through virus-spe...

May 6th, 2020 - HIV infection is known to cause profound and irreversible dysfunction of both innate and adaptive arms of the immune system. However, there is mounting evidence that early and aggressive treatment with antiretroviral drugs can prevent loss of immu...

May 6th, 2020 - Chronic pain affects a very high proportion of aging people living with HIV (aPLWH) and is thought to be related to both direct toxicity of HIV and antiretroviral therapy (ART) and by psychosocial factors that negatively affect pain (i.e. loneline...

May 5th, 2020 - A subset of HIV-infected patients, those with poor immunologic response to combined antiretroviral therapy (CD4+ T-cell count of less than 300-350 cells/mm^3) despite control of viremia, are at increased risk for both HIV-related and non-HIV-relat...

May 5th, 2020 - PRIMARY OBJECTIVES: I. To demonstrate safety and feasibility of ipilimumab and nivolumab at the standard doses of drug in solid tumor and relapsed refractory HIV-classical Hodgkin lymphoma (cHL) participants with human immunodeficiency virus (HIV)...

Jul 20th, 2021 - Dr Jean-Michel Molina The long-acting drug lenacapavir, a first-in-class capsid inhibitor, shows sustained viral suppression in a small cohort of heavily treatment-experienced patients with multidrug-resistant HIV at 26 weeks when combined with an...

Jul 15th, 2021 - "There are no interventions that have been shown to be effective in attaining viral suppression in people who inject drugs (PWID)," 2021 HIV/AIDS Research Avenir Award winner Hansel Tookes, MD, infectious disease specialist at the University of Mi...

Jun 24th, 2021 - Takeaway The ChAdOx1 nCoV-19 (AZD1222) vaccine given as a prime-boost regimen was well tolerated and produced similar immune responses in individuals with human immunodeficiency virus (HIV) well controlled on antiretroviral therapy (ART) vs those ...

Apr 30th, 2021 - NEW YORK (Reuters Health) - Growing availability of antiretroviral therapy (ART) has led to a rise in life expectancy among people living with HIV in Latin America and the Caribbean, according to a new study. Dr. Jessica L. Castilho told Reuters H...

Mar 17th, 2021 - NEW YORK (Reuters Health) - Replacing tenofovir disoproxil fumarate (TDF) with tenofovir alafenamide (TAF) in antiretroviral therapy (ART) regimens raises the risk of significant weight gain and worsening blood lipid levels in people living with H...