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About 113 results

ALLMedicine™ Blood Substitutes Center

Research & Reviews  40 results

The Use of Hemoglobin-Based Oxygen Carriers in Ex Vivo Machine Perfusion of Donor Organ...
https://doi.org/10.1097/MAT.0000000000001597
ASAIO Journal (American Society for Artificial Internal O... Lodhi S, Stone JP et. al.

Feb 28th, 2022 - There has been significant progress in the development of ex vivo machine perfusion for the nonischemic preservation of donor organs. However, several complications remain, including the logistics of using human blood for graft oxygenation and hem...

A Phase Ib/II in Patients With Acute Ischemic Stroke
https://clinicaltrials.gov/ct2/show/NCT02963376

Sep 24th, 2021 - Stroke is the fifth leading cause of death in the United States and is the leading cause of long term disability. Distinct geographic disparities in stroke mortality, with highest rates in the southeast United States including Arkansas, are known ...

Perfluorocarbons-Based 19F Magnetic Resonance Imaging in Biomedicine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537992
International Journal of Nanomedicine; Wu L, Liu F et. al.

Oct 17th, 2020 - Fluorine-19 (19F) magnetic resonance (MR) molecular imaging is a promising noninvasive and quantitative molecular imaging approach with intensive research due to the high sensitivity and low endogenous background signal of the 19F atom in vivo. Pe...

Alternatives to Transfusion.
https://doi.org/10.1093/ajcp/aqz175
American Journal of Clinical Pathology; Bachert SE, Dogra P et. al.

Nov 5th, 2019 - We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks. We contrib...

Data-Driven Identification of Adverse Event Reporting Patterns for Japan in VigiBase, t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858382
Drug Safety; Wakao R, Taavola H et. al.

Sep 29th, 2019 - Adverse event reporting patterns vary between countries, reflecting differences in reporting culture, clinical practice and underlying patient populations. Japan collects about 60,000 domestic adverse event reports yearly and shares serious report...

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Clinicaltrials.gov  3 results

A Phase Ib/II in Patients With Acute Ischemic Stroke
https://clinicaltrials.gov/ct2/show/NCT02963376

Sep 24th, 2021 - Stroke is the fifth leading cause of death in the United States and is the leading cause of long term disability. Distinct geographic disparities in stroke mortality, with highest rates in the southeast United States including Arkansas, are known ...

Increasing Dose Safety Study of Hemospan in Orthopedic Surgery Patients
https://clinicaltrials.gov/ct2/show/NCT00494949

Aug 19th, 2013 - Allogeneic (donor) blood transfusions are often required during and/or after orthopedic hip surgery to maintain adequate hemoglobin concentration, prevent tissue ischemia, treat hypotension, and compensate for fluid shifts. For example, during hos...

Allogeneic Vascularized Knee Transplantation
https://clinicaltrials.gov/ct2/show/NCT01133145

May 28th, 2010 - Sterile osseous defects of the knee joint are temporarily stabilised with a hinge arthroplasty or an intramedullary nail in the case of a long femoral defect. Assisted passive motion and isometric exercises are possible and necessary to avoid cont...

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News  2 results

Excess Mortality Seen with Hemoglobin-Based Blood Substitutes
https://www.medpagetoday.com/emergencymedicine/emergencymedicine/9263

Apr 28th, 2008 - Action Points Explain to interested patients that a meta-analysis found that hemoglobin-based blood substitutes increase serious risks without increasing clinical benefit. Point out that none of these products is FDA-approved. BETHESDA, Md., April...

Alternatives to Transfusion: A Case Report and Brief History of Artificial Oxygen Carriers
https://www.medscape.com/viewarticle/925171

Abstract and Introduction Abstract Objectives: We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. Methods: We provide a review of the notable products developed in both categories and includ...

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