ALLMedicine™ Blood Substitutes Center

Feb 28th, 2022 - There has been significant progress in the development of ex vivo machine perfusion for the nonischemic preservation of donor organs. However, several complications remain, including the logistics of using human blood for graft oxygenation and hem...

Sep 24th, 2021 - Stroke is the fifth leading cause of death in the United States and is the leading cause of long term disability. Distinct geographic disparities in stroke mortality, with highest rates in the southeast United States including Arkansas, are known ...

Oct 17th, 2020 - Fluorine-19 (19F) magnetic resonance (MR) molecular imaging is a promising noninvasive and quantitative molecular imaging approach with intensive research due to the high sensitivity and low endogenous background signal of the 19F atom in vivo. Pe...

Nov 5th, 2019 - We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks. We contrib...

Sep 29th, 2019 - Adverse event reporting patterns vary between countries, reflecting differences in reporting culture, clinical practice and underlying patient populations. Japan collects about 60,000 domestic adverse event reports yearly and shares serious report...

Sep 24th, 2021 - Stroke is the fifth leading cause of death in the United States and is the leading cause of long term disability. Distinct geographic disparities in stroke mortality, with highest rates in the southeast United States including Arkansas, are known ...

Aug 19th, 2013 - Allogeneic (donor) blood transfusions are often required during and/or after orthopedic hip surgery to maintain adequate hemoglobin concentration, prevent tissue ischemia, treat hypotension, and compensate for fluid shifts. For example, during hos...

May 28th, 2010 - Sterile osseous defects of the knee joint are temporarily stabilised with a hinge arthroplasty or an intramedullary nail in the case of a long femoral defect. Assisted passive motion and isometric exercises are possible and necessary to avoid cont...

Apr 28th, 2008 - Action Points Explain to interested patients that a meta-analysis found that hemoglobin-based blood substitutes increase serious risks without increasing clinical benefit. Point out that none of these products is FDA-approved. BETHESDA, Md., April...

Abstract and Introduction Abstract Objectives: We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. Methods: We provide a review of the notable products developed in both categories and includ...