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About 2,795 results

ALLMedicine™ Amniocentesis Center

Research & Reviews  905 results

Biomarkers in Obstetrical Complications
https://clinicaltrials.gov/ct2/show/NCT03480139

Jul 1st, 2022 - Objective: To study the natural history of normal pregnancy and the most frequent pregnancy complications responsible for the excessive rate of perinatal morbidity and mortality, in order to develop models to predict the occurrence of these compli...

Natural History of Maternal Neoplasia
https://clinicaltrials.gov/ct2/show/NCT04049604

Jul 1st, 2022 - Background: Starting in 2011, analysis of circulating cell-free DNA (cfDNA) in the blood of pregnant women began to be offered clinically as a prenatal screen for trisomies 13, 18, and 21. Owing to its superior sensitivity and positive predictive ...

Myelomeningocele Including Fetal Prescription.
https://doi.org/10.1542/pir.2022-001255
Pediatrics in Review; Hernandez NE, Bryant JP et. al.

Jul 1st, 2022 - Myelomeningocele (MMC) is one of the most common birth defects, affecting 0.2 to 0.4 per 1,000 live births in the United States. The most strongly associated risk factor is low folate level in pregnancy. For this reason, 0.4- to 1.0-mg supplementa...

Extracellular vesicles from amniotic fluid, milk, saliva, and urine expose complexes of...
https://doi.org/10.1111/jth.15801
Journal of Thrombosis and Haemostasis : JTH; Hu Y, Repa A et. al.

Jun 25th, 2022 - Tissue factor (TF) is expressed in the adventitia of the vessel wall and also commonly present on extracellular vesicles (EVs) in normal body fluids. TF and activated coagulation factor (F) VII(a) together form the so-called extrinsic tenase compl...

Procoagulant Activity in Amniotic Fluid Is Associated with Fetal-Derived Extracellular ...
https://doi.org/10.3390/cimb44060185
Current Issues in Molecular Biology; Butov KR, Karetnikova NA et. al.

Jun 24th, 2022 - Procoagulant activity in amniotic fluid (AF) is positively correlated with phosphatidylserine (PS) and tissue factor (TF)-expressing(+) extracellular vesicles (EVs). However, it is unknown if pathological fetal conditions may affect the compositio...

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Guidelines  11 results

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of is...
https://doi.org/10.1016/j.ajog.2021.06.079
American Journal of Obstetrics and Gynecology; , Prabhu M et. al.

Jun 26th, 2021 - Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have greatly evolved in the las...

Directive clinique no 409 : Tests diagnostiques fœtaux intra-utérins en cas d'infection...
https://doi.org/10.1016/j.jogc.2020.10.006
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Wilson RD

Dec 15th, 2020 - La présente directive clinique révisée met à jour les renseignements sur la prestation de soins aux femmes atteintes d'une infection virale chronique devant se soumettre à un test diagnostique fœtal intra-utérin. Femmes atteintes d'une infection v...

Guideline No. 409: Intrauterine Fetal Diagnostic Testing in Women with Chronic Viral In...
https://doi.org/10.1016/j.jogc.2020.09.007
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Wilson RD

Dec 15th, 2020 - This revised guideline provides updated information for the care of women with chronic viral infections who require intrauterine fetal diagnostic testing. Women with chronic viral infections who are pregnant or planning a pregnancy. Non-invasive s...

Guideline No. 410: Prevention, Screening, Diagnosis, and Pregnancy Management for Fetal...
https://doi.org/10.1016/j.jogc.2020.11.003
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Douglas Wilson R, Van Mieghem T et. al.

Nov 20th, 2020 - This revised guideline is intended to provide an update on the genetic aspects, prevention, screening, diagnosis, and management of fetal neural tube defects. Women who are pregnant or may become pregnant. Neural tube defect screening should be of...

Practice Bulletin No. 162 Summary: Prenatal Diagnostic Testing for Genetic Disorders.
https://doi.org/10.1097/AOG.0000000000001438
Obstetrics and Gynecology;

Apr 23rd, 2016 - Prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fetus. In contrast, prenatal genetic screening is designed to assess whether a pat...

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Drugs  5 results see all →

Clinicaltrials.gov  78 results

Biomarkers in Obstetrical Complications
https://clinicaltrials.gov/ct2/show/NCT03480139

Jul 1st, 2022 - Objective: To study the natural history of normal pregnancy and the most frequent pregnancy complications responsible for the excessive rate of perinatal morbidity and mortality, in order to develop models to predict the occurrence of these compli...

Natural History of Maternal Neoplasia
https://clinicaltrials.gov/ct2/show/NCT04049604

Jul 1st, 2022 - Background: Starting in 2011, analysis of circulating cell-free DNA (cfDNA) in the blood of pregnant women began to be offered clinically as a prenatal screen for trisomies 13, 18, and 21. Owing to its superior sensitivity and positive predictive ...

ANDDI-PRENATOME - Feasibility Study for a " Fast " Pangenomic High Throughput Sequencing Analysis in Prenatal Diagnosis
https://clinicaltrials.gov/ct2/show/NCT03964441

Jun 22nd, 2022 - Prenatal diagnosis of genetic diseases is a real medical challenge. The discovery of antenatal abnormalities on ultrasound is frequent (5 to 10% of pregnancies), and when an abnormalities is seen on ultrasound, it raises the possibility of an unde...

To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis
https://clinicaltrials.gov/ct2/show/NCT04831086

May 18th, 2022 - To evaluate whether the implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection: Optimises antenatal management (regarding steroids, tocolysis, antibiotics, maternal length stay duration) wi...

Comparison of the Non-invasive Approach and Fetal Exome Sequencing in Prenatal Diagnosis When Fetal Ultrasound Signs Are Discovered
https://clinicaltrials.gov/ct2/show/NCT05182242

Mar 15th, 2022 - The discovery of congenital malformations and/or non-specific signs by ultrasound (5% of pregnancies) represents a real medical challenge. Their prognosis is variable depending on the underlying etiology, ranging from acquired fetopathies to rare ...

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News  103 results

Clinical Edge Journal Scan Commentary: Prenatal Testing February 2022
https://www.mdedge.com/obgyn/article/251064/prenatal-testing/clinical-edge-journal-scan-commentary-prenatal-testing
Ryan Longman, MD

Jan 24th, 2022 - Ryan Longman, MD The field of obstetrics has always aimed to optimize the ability to screen pregnancies for aneuploidy; trisomy 21, trisomy 18, and trisomy 13. A recent study by Saito et al.

Low Risk of Fetal Chromosome Abnormality After Mosaic-Embryo Transfer
https://www.medscape.com/viewarticle/962176

Nov 5th, 2021 - NEW YORK (Reuters Health) - Embryos classified as mosaic are capable of producing healthy babies and should be considered for transfer when a euploid embryo is not available, say fertility specialists. Mosaic-embryo transfer (MET) following preimp...

Infectious disease pop quiz: Clinical challenges for the ObGyn
https://www.mdedge.com/obgyn/article/248281/mixed-topics/infectious-disease-pop-quiz-clinical-challenges-obgyn
Emily Susan Edwards, MD, MS, Patrick Duff, MD

Nov 4th, 2021 - In this question-and-answer article (the first in a series), our objective is to reinforce for the clinician several practical points of management for common infectious diseases. The principal references for the answers to the questions are 2 tex.

Genetic screening and diagnosis: Key advancements and the role of genetic counseling
https://www.mdedge.com/obgyn/article/240441/obstetrics/genetic-screening-and-diagnosis-key-advancements-and-role-genetic
Christopher R. Harman, MD, Amanda S. Higgs, MGC

May 23rd, 2021 - Preconception and prenatal genetic screening and diagnostic testing for genetic disorders are increasingly complex, with a burgeoning number of testing options and a shift in screening from situations identified as high-risk to more universal cons.

Gene, Stem-Cell Therapies Emerge as Options for Fetal Care
https://www.medscape.com/viewarticle/933799

Jul 14th, 2020 - NEW YORK (Reuters Health) - Fetal gene and stem-cell therapies are emerging as treatment options for select conditions, according to a new review. "Fetal cellular and gene therapies are feasible and primed to become viable treatments for a number ...

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Patient Education  16 results see all →