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About 28,803 results

ALLMedicine™ Bipolar Disorder Center

Research & Reviews  9,506 results

Changes in the structural brain connectome over the course of a nonrandomized clinical ...
https://doi.org/10.1038/s41386-022-01328-y 10.1007/s11920-004-0012-1 10.1007/s00787-020-01483-x 10.1002/hbm.23017 10.1007/s11682-017-9714-y 10.1016/j.jad.2018.04.069 10.1111/bdi.12782 10.1016/j.jad.2018.02.076 10.1007/s00213-011-2243-2 10.1111/bdi.12426 10.1111/bdi.13025 10.1038/nrn2575 10.1073/pnas.0911855107 10.1016/j.biopsych.2012.09.014 10.1016/j.pscychresns.2015.08.004 10.1038/nrn3465 10.1002/hbm.23534 10.1016/j.nicl.2018.03.030 10.1038/s41386-019-0586-2 10.1371/journal.pcbi.0010042 10.3389/fncom.2016.00012 10.1503/jpn.170214 10.1016/j.schres.2015.03.012 10.1016/j.jneumeth.2014.09.003 10.1002/brb3.448 10.1093/schbul/sby046 10.1097/00004583-199707000-00021 10.1192/bjp.133.5.429 10.1016/j.biopsych.2010.09.019 10.1002/mrm.1910340305 10.1111/bdi.12274 10.1016/j.neuroimage.2005.02.018 10.1006/nimg.2001.0978 10.1016/j.neuroimage.2009.10.003 10.1038/30918 10.1093/brain/awp089 10.1016/j.biopsych.2011.05.018 10.1371/journal.pcbi.0030017 10.1002/hbm.23347 10.2307/3033543 10.1016/j.jad.2013.03.004 10.1016/j.neuroimage.2012.05.048 10.1002/hbm.23111 10.1176/appi.ajp.2010.10060896 10.1016/j.biopsych.2010.03.036 10.1111/j.1399-5618.2012.01021.x 10.1016/j.euroneuro.2011.07.003 10.1038/s41386-021-00989-5 10.1016/j.jad.2021.05.086 10.1016/S0028-3908(02)00217-4 10.1016/j.neulet.2020.134916 10.1016/j.neubiorev.2013.01.003 10.4088/JCP.v63n0210 10.1002/hbm.20623 10.1177/0271678X21989246 10.1523/JNEUROSCI.0141-08.2008 10.1016/j.schres.2012.08.021 10.1016/j.neuron.2009.03.024
Neuropsychopharmacology : Official Publication of the Ame... Lei D, Li W et. al.

May 19th, 2022 - Disrupted topological organization of brain functional networks has been widely reported in bipolar disorder. However, the potential clinical implications of structural connectome abnormalities have not been systematically investigated. The presen...

Cardiac sodium channel inhibition by lamotrigine: in vitro characterization and clinica...
https://doi.org/10.1111/cts.13311
Clinical and Translational Science; Ingleby-Talecki L, van Dijkman SC et. al.

May 18th, 2022 - Lamotrigine, approved for use as an antiseizure medication (ASM) as well as the treatment of bipolar disorder, inhibits sodium channels in the brain to reduce repetitive neuronal firing and pathological release of glutamate. The shared homology of...

Effects of metabolic syndrome and obesity on suicidality in individuals with bipolar di...
https://doi.org/10.1016/j.jad.2022.05.062
Journal of Affective Disorders; Stenzel C, Dalkner N et. al.

May 18th, 2022 - The prevalence of metabolic syndrome and overweight/obesity is increased in bipolar disorder (BD) compared to the general population and is related to suicidality. The aim of this study was to examine the association between both the rate of suici...

Resting-state functional connectivity and spontaneous brain activity in early-onset bip...
https://doi.org/10.1016/j.jad.2022.05.055
Journal of Affective Disorders; Cattarinussi G, Bellani M et. al.

May 18th, 2022 - Early-onset bipolar disorder (BD) is a complex psychiatric illness characterized by mood swings, irritability and functional impairments. To improve our understanding of the pathophysiology of the disorder, we collected the existing resting-state ...

Differential trajectory of cognitive functions in neurocognitive subgroups of newly dia...
https://doi.org/10.1016/j.jad.2022.05.045
Journal of Affective Disorders; Kjærstad HL, Poulsen E et. al.

May 17th, 2022 - Cognitive impairments exist in a large proportion of remitted patients with bipolar disorder (BD). However, no study has investigated the cognitive trajectories across neurocognitive subgroups of patients or their unaffected first-degree relatives...

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Guidelines  9 results

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for...
https://doi.org/10.1111/bdi.13135
Bipolar Disorders; Yatham LN, Chakrabarty T et. al.

Oct 3rd, 2021 - The 2018 Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) guidelines provided clinicians with pragmatic treatment recommendations for bipolar disorder (BD). While these guidelines inc...

EPA guidance on physical activity as a treatment for severe mental illness: a meta-revi...
https://doi.org/10.1016/j.eurpsy.2018.07.004
European Psychiatry : the Journal of the Association of E... Stubbs B, Vancampfort D et. al.

Sep 28th, 2018 - Physical activity (PA) may be therapeutic for people with severe mental illness (SMI) who generally have low PA and experience numerous life style-related medical complications. We conducted a meta-review of PA interventions and their impact on he...

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947163
Bipolar Disorders; Yatham LN, Kennedy SH et. al.

Mar 15th, 2018 - The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published treatment guidelines for bipolar disorder in 2005, along with international commentaries and subsequent updates in 2007, 2009, and 2013. The last two updates were p...

Methodological recommendations for cognition trials in bipolar disorder by the Internat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282834
Bipolar Disorders; Miskowiak KW, Burdick KE et. al.

Sep 13th, 2017 - To aid the development of treatment for cognitive impairment in bipolar disorder, the International Society for Bipolar Disorders (ISBD) convened a task force to create a consensus-based guidance paper for the methodology and design of cognition t...

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Drugs  583 results see all →

Clinicaltrials.gov  340 results

Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
https://clinicaltrials.gov/ct2/show/NCT04684615

May 13th, 2022 - This protocol leverages existing NIMH studies and participants to accomplish time-sensitive research on the mental health impact of environmental stressors imposed by the COVID-19 pandemic. The study will describe the relationship between stressor...

Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Bipolar Disorder
https://clinicaltrials.gov/ct2/show/NCT03279224

May 4th, 2022 - The primary goals of this proof of concept study are to determine the effectiveness, safety and tolerability of FMT in adults with BD depression. Objective 1: To evaluate the effectiveness of the combination of a currently accepted approved therap...

This Phase 2, Double Blind, Placebo-controlled, Randomized Study is to Assess the Safety and Efficacy of Miricorilant in Obese Adult With Schizophrenia or Bipolar Disorder Treated With Antipsychoti...
https://clinicaltrials.gov/ct2/show/NCT03818256

May 3rd, 2022 - This is a randomized, double-blind, placebo-controlled study that will assess the safety, efficacy, and PK of miricorilant in obese patients with schizophrenia or bipolar disorder who are currently taking oral or injectable atypical antipsychotic ...

Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder
https://clinicaltrials.gov/ct2/show/NCT05179785

May 2nd, 2022 - This study aims to examine the effect of electroencephalography (EEG)-guided theta burst stimulation (TBS) on reducing mania/hypomania-related affect and reward driven behavior in adults with BD. Eligible participants will undergo 6 study visits: ...

Candesartan as an Adjunctive Treatment for Bipolar Depression
https://clinicaltrials.gov/ct2/show/NCT04430959

Apr 27th, 2022 - Pharmacological options for the treatment of Bipolar disorder (BD) are limited and a large proportion of patients does not show adequate response to treatment, especially in the case of bipolar depression. It has been hypothesized that dysfunction...

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News  1,063 results

Cats, toxoplasmosis, and psychosis: Understanding the risks
https://www.mdedge.com/psychiatry/article/254207/schizophrenia-other-psychotic-disorders/cats-toxoplasmosis-and-psychosis
E. Fuller Torrey, MD

May 2nd, 2022 - It has been clearly established that most human infectious diseases are caused by infectious agents that have been transmitted from animals to humans. 1 Based on published estimates from the 2000s, 60% to 76% of emerging infectious disease events a.

Medical Home Model of Primary Care Improves Mental Health Treatment
https://www.medscape.com/viewarticle/972951

Apr 29th, 2022 - A medical home that provides conventional primary care with a focus on mental health appears to be an effective model for managing patients with serious psychiatric illnesses, new research has found. Patients with serious mental illnesses such as ...

Schizophrenia Raises Risk of Inflammatory Bowel Disease
https://www.medscape.com/viewarticle/972866

Apr 28th, 2022 - Patients with schizophrenia are at increased risk of developing inflammatory bowel disease (IBD) compared with the general population, according to large study from Taiwan that provides more evidence of a gut-brain link. The study also shows that ...

Maternal RA tied to increased risk for mental disorders in their children
https://www.mdedge.com/rheumatology/article/254097/rheumatoid-arthritis/maternal-ra-tied-increased-risk-mental-disorders

Apr 26th, 2022 - Key clinical point: Children of mothers, but not fathers, with rheumatoid arthritis (RA) were predisposed to the risk of developing multiple mental disorders. Major finding: Children of mothers with RA had a significantly higher risk for autism sp.

Fast Five Quiz: How Much Do You Know About Tardive Dyskinesia?
https://www.medscape.com/viewarticle/910550

Apr 22nd, 2022 - Tardive dyskinesia (TD), according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), is a medication-induced movement disorder that causes involuntary repetitive muscle movements in the face, neck, arms, and legs...

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Patient Education  20 results see all →