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About 23,482 results

ALLMedicine™ Alzheimer Disease Center

Research & Reviews  11,153 results

Developmental ethanol exposure causes central nervous system dysfunction and may slow t...
https://doi.org/10.1016/j.alcohol.2021.03.006
Alcohol (Fayetteville, N.Y.); Belhorma K, Darwish N et. al.

May 7th, 2021 - Alcohol is a known teratogen, and developmental exposure to ethanol results in Fetal Alcohol Spectrum Disorder (FASD). Children born with FASD can exhibit a range of symptoms including low birth weight, microcephaly, and neurobehavioral problems. ...

Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis.
https://doi.org/10.1212/WNL.0000000000012109
Neurology Bellaver B, Ferrari-Souza JP et. al.

May 6th, 2021 - To perform a systematic review and meta-analysis to determine whether fluid and imaging astrocyte biomarkers are altered in Alzheimer's disease (AD). PubMed and Web of Science databases were searched for articles reporting fluid or imaging astrocy...

Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age.
https://doi.org/10.1212/WNL.0000000000012067
Neurology Ballarini T, Melo van Lent D et. al.

May 6th, 2021 - To determine if following a Mediterranean-like diet (MeDi) relates to cognitive functions and in vivo biomarkers for Alzheimer's disease (AD), we analyzed cross-sectional data from the German Longitudinal Cognitive Impairment and Dementia Study ME...

Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer ...
https://doi.org/10.1212/WNL.0000000000012108
Neurology Mayblyum DV, Becker JA et. al.

May 6th, 2021 - To compare how structural MRI, Fluorodeoxyglucose (FDG), and Flortaucipir (FTP) PET signal predict cognitive decline in high-amyloid versus low-amyloid participants with the goal of determining which biomarker combination would result in the highe...

Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease.
https://doi.org/10.1080/15548627.2021.1920814
Autophagy Roca-Agujetas V, de Dios C et. al.

May 4th, 2021 - Mitochondrial dysfunction is behind several neurodegenerative diseases, including Alzheimer disease (AD). Accumulation of damaged mitochondria is already observed at the early stages of AD and has been linked to impaired mitophagy, but the mechani...

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Guidelines  59 results

Sex Differences in Cognitive Decline Among US Adults
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2776902
JAMA Network Open; Levine DA, Gross AL et. al.

Feb 24th, 2021 - Sex differences in dementia risk are unclear. It is known that women have a greater prevalence of Alzheimer disease (AD) than men, at least partly because women live longer.1-3 Some, but not all, studies suggest that women have higher incidence of...

ACR Appropriateness Criteria® Dementia.
https://doi.org/10.1016/j.jacr.2020.01.040
Journal of the American College of Radiology : JACR; , Moonis G et. al.

May 6th, 2020 - Degenerative disease of the central nervous system is a growing public health concern. The primary role of neuroimaging in the workup of patients with probable or possible Alzheimer disease has typically been to exclude other significant intracran...

Falls Risk and Alzheimer Disease: A Patient Guide.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252520
Archives of Physical Medicine and Rehabilitation; Kahya M, Sood P et. al.

Mar 2nd, 2020 - Falls Risk and Alzheimer Disease: A Patient Guide.|2020|Kahya M,Sood P,Devos H,Krishnan S,Hirsch MA,|

In Alzheimer Research, Glucose Metabolism Moves to Center Stage
https://jamanetwork.com/journals/jama/fullarticle/2758712
JAMA Kuehn BM

Jan 7th, 2020 - Areas or patterns of reduced glucose metabolism are often seen in brain scans of patients with Alzheimer disease and other dementias. Now, a growing body of evidence suggests that glucose hypometabolism may be more than just a biomarker on brain s...

Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study
http://www.cmaj.ca/content/191/37/E1018
CMAJ

Sep 15th, 2019 - BACKGROUND: Donepezil, rivastigmine and galantamine are popular cholinesterase inhibitors used to manage the symptoms of Alzheimer disease and other dementias; regulatory agencies in several countries warn about a possible risk of rhabdomyolysis w...

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Drugs  5 results see all →

Clinicaltrials.gov  11,655 results

Developmental ethanol exposure causes central nervous system dysfunction and may slow t...
https://doi.org/10.1016/j.alcohol.2021.03.006
Alcohol (Fayetteville, N.Y.); Belhorma K, Darwish N et. al.

May 7th, 2021 - Alcohol is a known teratogen, and developmental exposure to ethanol results in Fetal Alcohol Spectrum Disorder (FASD). Children born with FASD can exhibit a range of symptoms including low birth weight, microcephaly, and neurobehavioral problems. ...

Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis.
https://doi.org/10.1212/WNL.0000000000012109
Neurology Bellaver B, Ferrari-Souza JP et. al.

May 6th, 2021 - To perform a systematic review and meta-analysis to determine whether fluid and imaging astrocyte biomarkers are altered in Alzheimer's disease (AD). PubMed and Web of Science databases were searched for articles reporting fluid or imaging astrocy...

Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age.
https://doi.org/10.1212/WNL.0000000000012067
Neurology Ballarini T, Melo van Lent D et. al.

May 6th, 2021 - To determine if following a Mediterranean-like diet (MeDi) relates to cognitive functions and in vivo biomarkers for Alzheimer's disease (AD), we analyzed cross-sectional data from the German Longitudinal Cognitive Impairment and Dementia Study ME...

Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer ...
https://doi.org/10.1212/WNL.0000000000012108
Neurology Mayblyum DV, Becker JA et. al.

May 6th, 2021 - To compare how structural MRI, Fluorodeoxyglucose (FDG), and Flortaucipir (FTP) PET signal predict cognitive decline in high-amyloid versus low-amyloid participants with the goal of determining which biomarker combination would result in the highe...

Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease.
https://doi.org/10.1080/15548627.2021.1920814
Autophagy Roca-Agujetas V, de Dios C et. al.

May 4th, 2021 - Mitochondrial dysfunction is behind several neurodegenerative diseases, including Alzheimer disease (AD). Accumulation of damaged mitochondria is already observed at the early stages of AD and has been linked to impaired mitophagy, but the mechani...

see more →

News  609 results

Sex Differences in Cognitive Decline Among US Adults
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2776902
JAMA Network Open; Levine DA, Gross AL et. al.

Feb 24th, 2021 - Sex differences in dementia risk are unclear. It is known that women have a greater prevalence of Alzheimer disease (AD) than men, at least partly because women live longer.1-3 Some, but not all, studies suggest that women have higher incidence of...

Fast Five Quiz: Alzheimer Disease Management
https://reference.staging.medscape.com/viewarticle/912045_2

Aug 18th, 2020 - Answer 1/5 Which of the following is the current standard pharmacologic treatment for Alzheimer disease in the United States and Europe? Your peers chose: Carbidopa/levodopa/entacapone 0% Cholinesterase inhibitors (ChEIs) and partial N-methyl-D-as...

Fast Five Quiz: Alzheimer Disease Management
https://reference.staging.medscape.com/viewarticle/912045

Aug 18th, 2020 - Alzheimer disease is a chronic, neurodegenerative disorder of the aging population that results in progressive cognitive and behavioral dysfunction. Afflicting more than 6 million Americans and more than 8 million Europeans, Alzheimer disease is t...

Fast Five Quiz: Alzheimer Disease Management
https://reference.staging.medscape.com/viewarticle/912045_5

Aug 18th, 2020 - In addition to the medications approved for Alzheimer disease, regular physical and cognitive exercise routines are strategies to prevent and slow disease progression. Increased cardiorespiratory fitness levels are associated with higher hippocamp...

Fast Five Quiz: Alzheimer Disease Management
https://reference.medscape.com/viewarticle/912045_3

Aug 18th, 2020 - Answer 2/5 Which of the following has been shown to achieve the highest levels of cognitive and functional abilities in patients with Alzheimer disease? Your peers chose: Early diagnosis and treatment 0% Antidepressants 0% Loop diuretics and CCBs ...

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Patient Education  1 results see all →