About 5,145 results

ALLMedicine™ Vascular Dementia Center

Research & Reviews  1,676 results

Temporal Dementia and Cognitive Impairment Trends in the Very Old in the 21st Century.
Journal of Alzheimer's Disease : JAD; Weidung B, Lövheim H et. al.

Mar 21st, 2023 - Long-increasing dementia incidence and prevalence trends may be shifting. Whether such shifts have reached the very old is unknown. To investigate temporal trends in the incidence of dementia and cognitive impairment and prevalence of dementia, co...

Comparing the risk of dementia in subjects with atrial fibrillation using non-vitamin K...
Age and Ageing; Grymonprez M, Petrovic M et. al.

Mar 20th, 2023 - Atrial fibrillation (AF) is associated with cognitive decline, with anticoagulated subjects potentially having a reduced risk compared with non-anticoagulated subjects. However, whether non-vitamin K antagonist oral anticoagulants (NOACs) may redu...

Neuroinflammation and amyloid deposition in the progression of mixed Alzheimer and vasc...
NeuroImage. Clinical; Ying C, Kang P et. al.

Mar 19th, 2023 - Alzheimer's disease (AD) and vascular contributions to cognitive impairment and dementia (VCID) pathologies coexist in patients with cognitive impairment. Abnormal amyloid beta (Aβ) deposition is the hallmark pathologic biomarker for AD. Neuroinfl...

Mutations in ARHGEF15 cause autosomal dominant hereditary cerebral small vessel disease...
Acta Neuropathologica; Ding X, Chen Y et. al.

Mar 18th, 2023 - Cerebral small vessel disease (CSVD) is a prominent cause of ischemic and hemorrhagic stroke and a leading cause of vascular dementia, affecting small penetrating vessels of the brain. Despite current advances in genetic susceptibility studies, ch...

Low vitamin D status is associated with inflammatory response in older patients with ce...
Journal of Neuroimmunology; Supriya M, Christopher R et. al.

Mar 16th, 2023 - This study aimed to determine the association of the NF-κB inflammatory signaling pathway with vitamin D status in older cerebral small vessel disease (SVD) patients. We measured serum 25(OH)D, pro-and anti-inflammatory cytokines, and mRNA levels ...

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Guidelines  1 results

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.
Alzheimer Disease and Associated Disorders; Sachdev P, Kalaria R et. al.

Mar 19th, 2014 - Several sets of diagnostic criteria have been published for vascular dementia since the 1960s. The continuing ambiguity in vascular dementia definition warrants a critical reexamination. Participants at a special symposium of the International Soc...

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Drugs  5 results see all →

Clinicaltrials.gov  128 results

Observational Study on Determinants of Dementia After Stroke

Mar 8th, 2023 - Risk of dementia is high after stroke but the mechanisms of post stroke dementia (PSD) are insufficiently understood. Specifically, there are few data on how vascular and neurodegenerative mechanisms interact in determining cognitive decline after...

Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia

Mar 8th, 2023 - Butylphthalide soft capsule is a synthetic chiral compound containing L- and D-isomers of butylphthalide. Studies in the past several decades have demonstrated that it could alleviate the learning and memory deficits induced by cerebral ischemia i...

The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule

Mar 7th, 2023 - Vascular dementia (VaD) is a clinical syndrome of acquired intellectual and functional impairment that results from cerebrovascular diseases. SaiLuoTong capsule is a traditional Chinese medicine compound; it is composed of ginseng extract (the mai...

CADASIL Disease Discovery

Feb 21st, 2023 - Small vessel diseases are conditions characterized by the narrowing of small arteries leading to an imbalance of blood supply upon demand. This results in a progressive chronic hypoperfusion with detrimental outcomes for the affected organ system ...

Intensive Blood Pressure Control in Ischaemic Stroke Patients With Severe Cerebral Small Vessel Disease

Feb 3rd, 2023 - Cerebral small vessel disease (SVD) is a common disease in patients with ischemic stroke and the most common cause of vascular dementia. The global burden of cerebral SVD is high and strategies to better prevent and manage cerebral SVD is urgently...

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News  233 results

Viruses Tied to Subsequent Dementia, Other Neurodegenerative Diseases

Jan 30th, 2023 - At least 22 viral illnesses were linked with an increased risk of subsequent neurodegenerative disease, NIH researchers found. Using data from the U.K. and Finland, Mike Nalls, PhD, of the NIH Center for Alzheimer's and Related Dementias, and co-a...

Cutting Back on Smoking No Help for Dementia Risk

Jan 19th, 2023 - Quitting smoking was associated with a lower risk of dementia, but cutting back was linked with an even higher risk, according to a Korean cohort study. In the study of nearly 800,000 participants, most of whom were men with a long history of smok...

Earlier Health Conditions Tied to Subsequent Dementia

Jan 5th, 2023 - Some health conditions associated with dementia appeared early and consistently long before diagnosis, while others became significant much later, a cohort study suggested. For people with a subsequent diagnosis of Alzheimer's disease, the earlies...

Dementia Accompanying Cardiometabolic Disease: Does It Come Down to Genetics?

Dec 29th, 2022 - There may be a limit to how much reducing cardiometabolic disease would lower the risk of dementia in older people genetically predisposed to both conditions, a twin study suggested. Twins over age 60 developed dementia at an incidence of 16.9% ov...

5-ARIs Not Linked to Risk of Dementia Over the Long Term

Dec 22nd, 2022 - Men taking 5α-reductase inhibitors (5-ARIs), commonly used for androgenic alopecia and benign prostatic hyperplasia (BPH), should be aware of possible adverse psychological effects, researchers warned. In a register-based cohort study of over 2.2 ...

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Patient Education  15 results see all →