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About 3,855 results

ALLMedicine™ Restless Legs Syndrome Center

Research & Reviews  1,232 results

Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
https://clinicaltrials.gov/ct2/show/NCT03082755

May 18th, 2022 - Nighttime agitation and sleep disturbance in persons with dementia (PWD) causes patient suffering, may accelerate cognitive decline, leads to burdened caregivers, and is costly to manage. Pharmacological interventions are primarily antipsychotics ...

The conundrum of the origin of restless legs syndrome.
https://doi.org/10.1093/sleep/zsac018
Sleep Lin WS

May 14th, 2022 - The conundrum of the origin of restless legs syndrome.|2022|Lin WS,|

Striatal mechanism of the restless legs syndrome.
https://doi.org/10.1093/sleep/zsac110
Sleep Lai YY, Hsieh KC et. al.

May 11th, 2022 - Brain iron deficiency has been reported to be associated with the restless legs syndrome (RLS). However, 30%-50% of RLS patients do not respond to iron therapy, indicating that mechanisms other than brain iron deficiency may also participate in th...

Revisiting brain iron deficiency in restless legs syndrome using magnetic resonance ima...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065426
NeuroImage. Clinical; Beliveau V, Stefani A et. al.

May 3rd, 2022 - Studies on brain iron content in restless legs syndrome (RLS) using magnetic resonance imaging (MRI) are heterogeneous. In this study, we sought to leverage the availability of a large dataset including a range of iron-sensitive MRI techniques to ...

ExomeChip-based rare variant association study in restless legs syndrome.
https://doi.org/10.1016/j.sleep.2022.04.001
Sleep Medicine; Tilch E, Schormair B et. al.

May 1st, 2022 - Restless legs syndrome (RLS) is a common sleep-related movement disorder in populations of European descent and disease risk is strongly influenced by genetic factors. Common variants have been assessed extensively in several genome-wide associati...

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Guidelines  1 results

Consensus clinical practice guidelines for the diagnosis and treatment of restless legs...
https://doi.org/10.1016/j.smrv.2014.10.009
Sleep Medicine Reviews; Picchietti DL, Hensley JG et. al.

Jan 3rd, 2015 - Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is common during pregnancy, affecting approximately one in five pregnant women in Western countries. Many report moderate or severe symptoms and negative impact on sleep. There is very little...

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Drugs  100 results see all →

Clinicaltrials.gov  53 results

Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
https://clinicaltrials.gov/ct2/show/NCT03082755

May 18th, 2022 - Nighttime agitation and sleep disturbance in persons with dementia (PWD) causes patient suffering, may accelerate cognitive decline, leads to burdened caregivers, and is costly to manage. Pharmacological interventions are primarily antipsychotics ...

Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome During Opioid Medication Reduction
https://clinicaltrials.gov/ct2/show/NCT04698343

Apr 28th, 2022 - For RLS patients taking a stable dose of prescription opioid medications prior to study entry, iterative opioid dose reduction is performed in conjunction with open-label NPNS treatment. For each of two iterative step-downs in opioid dose (step-do...

Fibromyalgia Syndrome in France: The Role of Assessment and Management of Sleep Disorders
https://clinicaltrials.gov/ct2/show/NCT04775368

Mar 3rd, 2022 - The FIBOBS study is a multi-center, interventional, prospective study carried out within specialized chronic pain structures (CPS) in metropolitan France. It will estimate the prevalence of sleep disorders, divided into three categories (poor qual...

Stretching Exercises Versus Thermotherapy on Restless Legs Syndrome Symptoms
https://clinicaltrials.gov/ct2/show/NCT05261035

Mar 2nd, 2022 - a quasi-experimental study was carried out at the antenatal outpatient clinic of XXXX. A sample of 60 pregnant women was randomly assigned to two groups. One group was instructed to perform stretching exercises daily for one week, and the other gr...

The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation
https://clinicaltrials.gov/ct2/show/NCT05012605

Jan 27th, 2022 - The overall goal in this project is to develop an in-depth understanding of the complex interplay between non-obstructive sleep apnea (non OSA) sleep disorders and recovery after stroke. Sleep is vital to overall health and quality of life. Abnorm...

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News  143 results

Restless Legs Syndrome Common in X-linked Adrenoleukodystrophy
https://www.medscape.com/viewarticle/971868

Apr 8th, 2022 - Restless legs syndrome occurred in approximately 40% of adults with X-linked adrenoleukodystrophy, based on data from 32 individuals. Dr John Winkelman Patients with X-linked adrenoleukodystrophy (ALD), a neurodegenerative disease, often experienc...

Restless legs syndrome occurs often in X-linked adrenoleukodystrophy
https://www.mdedge.com/psychiatry/article/253569/movement-disorders/restless-legs-syndrome-occurs-often-x-linked
Heidi Splete

Apr 7th, 2022 - Restless legs syndrome occurred in approximately 40% of adults with X-linked adrenoleukodystrophy, based on data from 32 individuals. Patients with X-linked adrenoleukodystrophy (ALD), a neurodegenerative disease, often experience gait and balance.

Restless legs syndrome surged early during pandemic
https://www.mdedge.com/psychiatry/article/251709/movement-disorders/restless-legs-syndrome-surged-early-during-pandemic
Heidi Splete

Feb 11th, 2022 - Individuals with restless legs syndrome showed an increase in symptom severity in the early phase of the COVID-19 pandemic in the United States in 2020, but this increase had waned by 2021, according to data from 500 participants in the National R.

Restless Legs Syndrome Surged Early During COVID Pandemic
https://www.medscape.com/viewarticle/968396

Feb 11th, 2022 - Individuals with restless legs syndrome showed an increase in symptom severity in the early phase of the COVID-19 pandemic in the United States in 2020, but this increase had waned by 2021, according to data from 500 participants in the National R...

Stroke-Related Restless Legs Syndrome an 'Emerging Entity'
https://www.medscape.com/viewarticle/966725

Jan 17th, 2022 - More data support the concept of stroke-related restless legs syndrome as an "emerging entity," investigators report in a new study. New research has identified the lenticulostriate and ventral brainstem as the main regions implicated in stroke-re...

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Patient Education  13 results see all →