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About 3,833 results

ALLMedicine™ Opioid Abuse Center

Research & Reviews  1,447 results

Gabapentin controlled substance status.
https://doi.org/10.1016/j.japh.2021.01.025
Journal of the American Pharmacists Association : JAPhA; Campbell LS, Coomer TN et. al.

Mar 6th, 2021 - Gabapentin is approved to treat postherpetic neuralgia and epilepsy with partial-onset seizures. The large majority of gabapentin prescribing is off label. Gabapentin may be abused for euphoria, potentiating the high from opiates, reduction of alc...

Epigenome-wide study of brain DNA methylation following acute opioid intoxication.
https://doi.org/10.1016/j.drugalcdep.2021.108658
Drug and Alcohol Dependence; Shu C, Sosnowski DW et. al.

Mar 5th, 2021 - Opioid abuse poses significant risk to individuals in the United States and epigenetic changes are a leading potential biomarker of opioid abuse. Current evidence, however, is mostly limited to candidate gene analysis in whole blood. To clarify th...

Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related g...
https://doi.org/10.1016/j.drugalcdep.2021.108598
Drug and Alcohol Dependence; Liu SX, Gades MS et. al.

Feb 24th, 2021 - Opioid abuse is a chronic disorder likely involving stable neuroplastic modifications. While a number of molecules contributing to these changes have been identified, the broader spectrum of genes and gene networks that are affected by repeated op...

Zebrafish (Danio rerio) larvae show behavioral and embryonic development defects when e...
https://doi.org/10.1016/j.ntt.2021.106964
Neurotoxicology and Teratology; Sales Cadena MR, Cadena PG et. al.

Feb 23rd, 2021 - Opioid abuse continues to plague society, and in recent years, there has been an epidemic, leading to increased addiction and death. It is poorly understood how prenatal opioid use affects the lives of children. The aim of this work was to evaluat...

Understanding barriers to treatment among individuals not engaged in treatment who misu...
https://doi.org/10.1080/08897077.2021.1876199
Substance Abuse; Cavazos-Rehg P, Xu C et. al.

Feb 22nd, 2021 - Background: Many individuals misusing opioids do not enter into treatment. The question of who enters into treatment for their opioid abuse and under what circumstances is complex and shaped by multiple factors. The objective of the current study ...

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Guidelines  83 results

Opioid Medications | FDA
https://www.fda.gov/drugs/information-drug-class/opioid-medications

Jun 30th, 2019 - FDA takes actions to combat prescription opioid abuse. Prescription opioids are powerful pain-reducing medications that include prescription oxycodone, hydrocodone and morphine. These medications can help manage pain when prescribed for the right ...

A Transitioning Epidemic: How The Opioid Crisis Is Driving The Rise In Hepatitis C
https://www.healthaffairs.org/doi/abs/10.1377/hlthaff.2018.05232?journalCode=hlthaff
Powell,D.,et al

Feb 3rd, 2019 - The hepatitis C virus is responsible for more deaths in the United States than any other infectious disease, and hepatitis C infections have been rising at an alarming rate since 2010. We evaluated the role of the opioid epidemic and, in particula...

Effective management of opioid withdrawal symptoms: A gateway to opioid dependence treatment
https://onlinelibrary.wiley.com/doi/full/10.1111/ajad.12862
Kosten,T.,et al

Jan 30th, 2019 - The opioid crisis has taken an immense toll in the United States. On average, five lives are lost to an opioid overdose every hour of the day; estimated costs associated with opioid misuse exceed $500 billion annually. Illicit opioid discontinuati...

National Trends in Hospitalizations for Stroke Associated With Infective Endocarditis and Opioid Use Between 1993 and 2015
https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.118.024436
Omran,S.,et al

Jan 29th, 2019 - There has been a recent sharp rise in opioid-related deaths in the United States. Intravenous opioid use can lead to infective endocarditis (IE) which can result in stroke. There are scant data on recent trends in this neurological complication of...

Challenges with Implementing the Centers for Disease Control and Prevention Opioid Guideline: A Consensus Panel Report
https://academic.oup.com/painmedicine/advance-article-abstract/doi/10.1093/pm/pny307/5301726?redirectedFrom=fulltext
Kroenke,K.,et al

Jan 24th, 2019 - A national crisis of opioid-related morbidity, mortality, and misuse has led to initiatives to address the appropriate role of opioids to treat pain. Deployment of a guideline from the Centers for Disease Control and Prevention to reduce the risks...

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Drugs  7 results see all →

Clinicaltrials.gov  1,853 results

Gabapentin controlled substance status.
https://doi.org/10.1016/j.japh.2021.01.025
Journal of the American Pharmacists Association : JAPhA; Campbell LS, Coomer TN et. al.

Mar 6th, 2021 - Gabapentin is approved to treat postherpetic neuralgia and epilepsy with partial-onset seizures. The large majority of gabapentin prescribing is off label. Gabapentin may be abused for euphoria, potentiating the high from opiates, reduction of alc...

Epigenome-wide study of brain DNA methylation following acute opioid intoxication.
https://doi.org/10.1016/j.drugalcdep.2021.108658
Drug and Alcohol Dependence; Shu C, Sosnowski DW et. al.

Mar 5th, 2021 - Opioid abuse poses significant risk to individuals in the United States and epigenetic changes are a leading potential biomarker of opioid abuse. Current evidence, however, is mostly limited to candidate gene analysis in whole blood. To clarify th...

Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related g...
https://doi.org/10.1016/j.drugalcdep.2021.108598
Drug and Alcohol Dependence; Liu SX, Gades MS et. al.

Feb 24th, 2021 - Opioid abuse is a chronic disorder likely involving stable neuroplastic modifications. While a number of molecules contributing to these changes have been identified, the broader spectrum of genes and gene networks that are affected by repeated op...

Zebrafish (Danio rerio) larvae show behavioral and embryonic development defects when e...
https://doi.org/10.1016/j.ntt.2021.106964
Neurotoxicology and Teratology; Sales Cadena MR, Cadena PG et. al.

Feb 23rd, 2021 - Opioid abuse continues to plague society, and in recent years, there has been an epidemic, leading to increased addiction and death. It is poorly understood how prenatal opioid use affects the lives of children. The aim of this work was to evaluat...

Understanding barriers to treatment among individuals not engaged in treatment who misu...
https://doi.org/10.1080/08897077.2021.1876199
Substance Abuse; Cavazos-Rehg P, Xu C et. al.

Feb 22nd, 2021 - Background: Many individuals misusing opioids do not enter into treatment. The question of who enters into treatment for their opioid abuse and under what circumstances is complex and shaped by multiple factors. The objective of the current study ...

see more →

News  441 results

Opioid Prescribing for High-Risk Patients Continues to Rise
https://www.medscape.com/viewarticle/942287

Dec 8th, 2020 - Since the publication of the Centers for Disease Control and Prevention's (CDC's) opioid guideline in March 2016, there has been a substantial drop in the prescription rate for these medications ― except for patients at highest risk for opioid abu...

NSAID Allergy Ups Risk for Opioid Abuse in Osteoarthritis
https://www.medscape.com/viewarticle/941443

Nov 22nd, 2020 - Patients with osteoarthritis and an allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) are more likely to become addicted to opioids than nonallergic patients, according to a 5-year retrospective analysis. In fact, the risk of developing an ...

Dangers of a Medical Board Investigation: How to Protect Yourself
https://www.medscape.com/viewarticle/940672

Nov 9th, 2020 - Cynthia H. Moran, MD, has a medical degree, a passion for treating the elderly, and a desire to work. What she doesn't have is a job or hopes of getting one anytime soon. The Houston physician has never been charged with a crime, but she did run a...

US Prescription Opioid Abuse Was Declining Before Pandemic
https://www.staging.medscape.com/viewarticle/939056

Oct 13th, 2020 - NEW YORK (Reuters Health) - Prescription opioid abuse in the United States declined dramatically from 2009 to 2018, raw data indicate. Weighted data also showed a statistically significant decline, although less dramatic, according to findings pre...

US Prescription Opioid Abuse Was Declining Before Pandemic
https://www.medscape.com/viewarticle/939056

Oct 13th, 2020 - NEW YORK (Reuters Health) - Prescription opioid abuse in the United States declined dramatically from 2009 to 2018, raw data indicate. Weighted data also showed a statistically significant decline, although less dramatic, according to findings pre...

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Patient Education  2 results see all →