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About 84,405 results

ALLMedicine™ Schizophrenia Center

Research & Reviews  27,487 results

3 steps to bend the curve of schizophrenia
https://www.mdedge.com/psychiatry/article/255916/schizophrenia-other-psychotic-disorders/3-steps-bend-curve-schizophrenia
Henry A. Nasrallah, MD

Jul 1st, 2022 - Schizophrenia is arguably the most serious psychiatric brain syndrome. It disables teens and young adults and robs them of their potential and life dreams.

Adaptive changes to antipsychotics: How to avoid the consequences
https://www.mdedge.com/psychiatry/article/255918/schizophrenia-other-psychotic-disorders/adaptive-changes-antipsychotics
Ahmad Sleem, MBBCh, Rif S. El-Mallakh, MD

Jul 1st, 2022 - While our understanding of the mechanisms of psychosis continues to evolve beyond the dopamine hypothesis, the key role of dopamine in psychosis and its treatment has not faded. 1 Over time, the dopamine hypothesis of schizophrenia has evolved from.

Effects of multitask training on cognition and motor control in people with schizophren...
https://doi.org/10.1371/journal.pone.0264745
PloS One; Chien TY, Chern JS et. al.

Jul 1st, 2022 - Schizophrenia spectrum disorder (SSD) is a disabling mental illness that causes considerable deficits in motor and cognitive functions. The purpose of this study was to examine the effects of combining traditional multitask training (TMT) and vide...

Integration of multidimensional splicing data and GWAS summary statistics for risk gene...
https://doi.org/10.1371/journal.pgen.1009814
PLoS Genetics; Ji Y, Wei Q et. al.

Jul 1st, 2022 - A common strategy for the functional interpretation of genome-wide association study (GWAS) findings has been the integrative analysis of GWAS and expression data. Using this strategy, many association methods (e.g., PrediXcan and FUSION) have bee...

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.
https://doi.org/10.1371/journal.pone.0269404
PloS One; Kragness S, Clark Z et. al.

Jul 1st, 2022 - Micropeptides, encoded from small open reading frames of 300 nucleotides or less, are hidden throughout mammalian genomes, though few functional studies of micropeptides in the brain are published. Here, we describe a micropeptide known as the Pla...

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Guidelines  10 results

The American Psychiatric Association Practice Guideline for the Treatment of Patients W...
https://doi.org/10.1176/appi.ajp.2020.177901
The American Journal of Psychiatry; Keepers GA, Fochtmann LJ et. al.

Sep 2nd, 2020 - The American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia.|2020|Keepers GA,Fochtmann LJ,Anzia JM,Benjamin S,Lyness JM,|methods,methods,methods,classification,therapeutic use,diagnosis,therapy,

Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated r...
https://doi.org/10.1177/0269881119889296
Journal of Psychopharmacology (Oxford, England); Barnes TR, Drake R et. al.

Dec 13th, 2019 - These updated guidelines from the British Association for Psychopharmacology replace the original version published in 2011. They address the scope and targets of pharmacological treatment for schizophrenia. A consensus meeting was held in 2017, i...

EPA guidance on physical activity as a treatment for severe mental illness: a meta-revi...
https://doi.org/10.1016/j.eurpsy.2018.07.004
European Psychiatry : the Journal of the Association of E... Stubbs B, Vancampfort D et. al.

Sep 28th, 2018 - Physical activity (PA) may be therapeutic for people with severe mental illness (SMI) who generally have low PA and experience numerous life style-related medical complications. We conducted a meta-review of PA interventions and their impact on he...

BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascu...
https://doi.org/10.1177/0269881116645254
Journal of Psychopharmacology (Oxford, England); Cooper SJ, Reynolds GP et. al.

May 6th, 2016 - Excess deaths from cardiovascular disease are a major contributor to the significant reduction in life expectancy experienced by people with schizophrenia. Important risk factors in this are smoking, alcohol misuse, excessive weight gain and diabe...

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biologica...
https://doi.org/10.3109/15622975.2012.696143
The World Journal of Biological Psychiatry : the Official... Hasan A, Falkai P et. al.

Jul 28th, 2012 - These updated guidelines are based on a first edition of the World Federation of Societies of Biological Psychiatry Guidelines for Biological Treatment of Schizophrenia published in 2005. For this 2012 revision, all available publications pertaini...

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Drugs  953 results see all →

Clinicaltrials.gov  2,941 results

Genetic Study of Schizophrenia
https://clinicaltrials.gov/ct2/show/NCT00001486

Jun 24th, 2022 - Objective: Schizophrenia is a complex genetic disorder which likely involves many genes each producing a slight increase in risk. Finding weak-acting genes in complex genetic disorders has been challenging and will likely require a number of appro...

Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT00004571

Jun 24th, 2022 - This protocol is meant to provide a matrix for multiple, simultaneous brain imaging investigations using magnetic resonance imaging (MRI) at 3.0 Tesla (3T). We intend to study regional brain structure, physiology, and biochemistry in living human ...

Inpatient Evaluation of Adults With Schizophrenia
https://clinicaltrials.gov/ct2/show/NCT00001247

Jun 24th, 2022 - Objectives: Schizophrenia and related psychoses are chronic brain disorders whose prognosis is often poor and whose pathophysiology remains obscure. Neuroimaging technologies such as PET (positron emission tomography), fMRI (functional magnetic re...

Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT00001246

Jun 24th, 2022 - Objective: Our work is driven by the core hypotheses that many of the most severe neuropsychiatric disorders of childhood onset are associated with deviations from the path of normal brain development, the neuroanatomical substrates of which can b...

Studies of Frontal Lobe Brain Functioning in Schizophrenia
https://clinicaltrials.gov/ct2/show/NCT00001258

Jun 24th, 2022 - The purpose of this work is to investigate the role of the frontal lobe, and its connections for cognition in health and in neuropsychiatric diseases, particularly schizophrenia. Regional cerebral blood flow (rCBF) will be measured with oxygen-15 ...

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News  2,359 results

3 steps to bend the curve of schizophrenia
https://www.mdedge.com/psychiatry/article/255916/schizophrenia-other-psychotic-disorders/3-steps-bend-curve-schizophrenia
Henry A. Nasrallah, MD

Jul 1st, 2022 - Schizophrenia is arguably the most serious psychiatric brain syndrome. It disables teens and young adults and robs them of their potential and life dreams.

Adaptive changes to antipsychotics: How to avoid the consequences
https://www.mdedge.com/psychiatry/article/255918/schizophrenia-other-psychotic-disorders/adaptive-changes-antipsychotics
Ahmad Sleem, MBBCh, Rif S. El-Mallakh, MD

Jul 1st, 2022 - While our understanding of the mechanisms of psychosis continues to evolve beyond the dopamine hypothesis, the key role of dopamine in psychosis and its treatment has not faded. 1 Over time, the dopamine hypothesis of schizophrenia has evolved from.

Best Strategy to Prevent Schizophrenia Relapse Yields Unexpected Results
https://www.medscape.com/viewarticle/976372

Jun 29th, 2022 - A large meta-analysis sheds light on the best antipsychotic maintenance strategy to prevent relapse in clinically-stable schizophrenia — with some unexpected results that have potential implications for changes to current guidelines. Consistent wi...

Sleep a Potential Treatment Target for Schizophrenia?
https://www.medscape.com/viewarticle/976216

Jun 27th, 2022 - A new analysis reveals a bidirectional relationship between sleep patterns and schizophrenia, leading researchers to suggest that sleep may be a potential treatment target for the disorder. Applying a Mendelian randomization (MR) approach, the inv...

Transdermal Med May Directly Target Hostility in Schizophrenia
https://www.medscape.com/viewarticle/976028

Jun 22nd, 2022 - HP-3070, an asenapine transdermal system, is superior to placebo in reducing schizophrenia-associated hostility, results of a phase 3 study show. The results suggest that these effects are at least partially independent of general antipsychotic ef...

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Patient Education  12 results see all →