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About 61,593 results

ALLMedicine™ Tuberculosis Center

Research & Reviews  22,649 results

Impact and benefit-cost ratio of a program for the management of latent tuberculosis in...
https://doi.org/10.1371/journal.pone.0267781
PloS One; Pépin J, Desjardins F et. al.

May 20th, 2022 - The identification and treatment of latent tuberculosis infection (LTBI) among immigrants from high-incidence regions who move to low-incidence countries is generally considered an ineffective strategy because only ≈14% of them comply with the mul...

Remote analysis of sputum smears for mycobacterium tuberculosis quantification using di...
https://doi.org/10.1371/journal.pone.0268494
PloS One; Delgado LG, Postigo M et. al.

May 20th, 2022 - Worldwide, TB is one of the top 10 causes of death and the leading cause from a single infectious agent. Although the development and roll out of Xpert MTB/RIF has recently become a major breakthrough in the field of TB diagnosis, smear microscopy...

Aerosolization of Mycobacterium tuberculosis by Tidal Breathing.
https://doi.org/10.1164/rccm.202110-2378OC
American Journal of Respiratory and Critical Care Medicine; Dinkele R, Gessner S et. al.

May 19th, 2022 - Interrupting tuberculosis (TB) transmission requires an improved understanding of how - and when - the causative organism, Mycobacterium tuberculosis (Mtb), is aerosolized. Although cough is commonly assumed to be the dominant source of Mtb aeroso...

Analysis of risk factors for pulmonary tuberculosis with persistent severe inflammation...
https://doi.org/10.1097/MD.0000000000029297
Medicine Shimoda M, Yoshiyama T et. al.

May 19th, 2022 - Patients with pulmonary tuberculosis (TB) sometimes show persistent severe inflammation for more than 1 month, even if TB treatment is effective. Although this inflammation can be improved through continuous antituberculous therapy, the risk facto...

Clinicoepidemiological characteristics of cutaneous tuberculosis in 1458 Indian patient...
https://doi.org/10.1111/ijd.16267
International Journal of Dermatology; Singal A, Kaur I et. al.

May 19th, 2022 - Tuberculosis (TB) has been one of the most challenging infectious diseases globally. Cutaneous tuberculosis (CTB) accounts for 0.5-2% of extrapulmonary TB and is often missed owing to its varying morphology and paucibacillary nature. In this retro...

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Guidelines  28 results

WHO consolidated guidelines on tuberculosis Module 5: Management of tuberculosis in children and adolescents
https://www.who.int/publications/i/item/9789240046764
World Health Organization (WHO)

Mar 21st, 2022 - The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatmen...

Interim Guidance: 4-Month Rifapentine-Moxifloxacin Regimen for the Treatment of Drug-Su...
https://doi.org/10.15585/mmwr.mm7108a1
MMWR. Morbidity and Mortality Weekly Report; Carr W, Kurbatova E et. al.

Feb 25th, 2022 - On May 5, 2021, CDC's Tuberculosis Trials Consortium and the National Institutes of Health (NIH)-sponsored AIDS Clinical Trials Group (ACTG) published results from a randomized controlled trial indicating that a 4-month regimen containing rifapent...

Cancer immunotherapy in special challenging populations: recommendations of the Advisor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009216
Journal for Immunotherapy of Cancer; Gonzalez-Cao M, Puertolas T et. al.

Mar 31st, 2021 - Cancer immunotherapy based on the use of antibodies targeting the so-called checkpoint inhibitors, such as programmed cell death-1 receptor, its ligand, or CTLA-4, has shown durable clinical benefit and survival improvement in melanoma and other t...

Multisystem inflammatory syndrome in an adult with SARS-CoV-2 infection.
https://doi.org/10.1016/j.arbres.2020.03.021
European Heart Journal. Cardiovascular Imaging; Chowdhary A, Joy E et. al.

Sep 6th, 2020 - New evidence and knowledge about the clinical management of drug-resistant tuberculosis (TB) in the last 3 years, makes it necessary to update the recent guideline published by SEPAR in 2017, mainly in relation to new diagnostic methods, drug clas...

2019 update of the European AIDS Clinical Society Guidelines for treatment of people li...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754379
HIV Medicine; Ryom L, Cotter A et. al.

Sep 5th, 2020 - The European AIDS Clinical Society (EACS) Guidelines cover key aspects of HIV management with major updates every two years. The 2019 Guidelines were extended with a new section focusing on drug-drug interactions and other prescribing issues in pe...

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Drugs  382 results see all →

Clinicaltrials.gov  428 results

Trial of Vitamin D Supplementation in Cape Town Primary Schoolchildren
https://clinicaltrials.gov/ct2/show/NCT02880982

May 13th, 2022 - The investigators will conduct a n=5,400 Phase 3, double-blind, individually randomised placebo-controlled clinical trial of 5 years' duration in primary schools in City of Cape Town Metropolitan Municipality, Western Cape Province, Republic of So...

The Influence of Malnutrition, Diabetes Mellitus, and Helminth Infections on Biosignatures in Latent Tuberculosis in a South Indian Population
https://clinicaltrials.gov/ct2/show/NCT04526613

May 13th, 2022 - Approximately 2 billion people worldwide are infected with Mycobacterium tuberculosis (TB), with 90% of individuals having latent infection (LTBI). The control of TB requires clearly delineated helper T cell (Th) 1 responses and, to a lesser exten...

Using Biomarkers to Predict TB Treatment Duration
https://clinicaltrials.gov/ct2/show/NCT02821832

May 13th, 2022 - Shortening the duration of treatment for patients with drug sensitive tuberculosis from 6 to 4 months has been attempted many times in clinical trials but thus far all have failed. These failures reveal our incomplete understanding of factors driv...

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung
https://clinicaltrials.gov/ct2/show/NCT05027958

May 13th, 2022 - We propose a pilot study in which we employ directed bronchoscopic instillation of Mycobacterium tuberculosis (Mtb)-derived Purified Protein Derivative (PPD) to evaluate local airway immune response in adults with or without latent tuberculosis in...

NexGen EBA Radiologic and Immunologic Biomarkers of Sterilizing Drug Activity in Tuberculosis
https://clinicaltrials.gov/ct2/show/NCT02371681

May 13th, 2022 - Early bactericidal activity (EBA), which measures decline in serial sputum colony forming unit (CFU) counts over the first 2-14 days of treatment, has been used extensively as a means of initially evaluating the potency of individual or combinatio...

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News  1,126 results

Tuberculosis: The Disease That Changed World History
https://www.medscape.com/viewarticle/974044

May 16th, 2022 - Almost forgotten today, tuberculosis (TB) is still one of the deadliest infectious diseases in the world. In an interview with Coliquio, Ronald D. Gerste, MD, PhD, an ophthalmologist and historian, looked back on this disease's eventful history, w...

New HIV Care Guidelines From the European AIDS Clinical Society
https://www.medscape.com/viewarticle/973524

May 5th, 2022 - Version 11.0 of the 2021 revised European AIDS Clinical Society (EACS) Guidelines updates all aspects of HIV care and adds recommendations on COVID-19 and antiretroviral treatment (ART) in children and adolescents, the guidelines authors report in...

Worst TB Outbreak in 20 Years Reported in Washington State
https://www.medscape.com/viewarticle/973417

May 4th, 2022 - Tuberculosis cases are increasing in Washington, which has put public health officials on "heightened alert," according to a recent announcement from the Washington State Department of Health. Widespread disruptions in health care and missed tuber...

Nail in the Coffin for Injectable Therapy in Drug-Resistant TB?
https://www.medpagetoday.com/infectiousdisease/tuberculosis/98532

May 3rd, 2022 - Oral treatment containing bedaquiline was associated with better outcomes for patients with drug-resistant tuberculosis (TB) compared with an injectable treatment regimen, a retrospective cohort study showed. In adjusted analyses, the rate of trea...

Tuberculosis Clinical Practice Guidelines (WHO, 2022)
https://www.medscape.com/viewarticle/972831

Apr 29th, 2022 - 2022 clinical practice guidelines for the management of tuberculosis (TB) in children and adolescents were published online on March 21 by the World Health Organization (WHO) as part of the WHO Consolidated Guidelines on Tuberculosis. New recommen...

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Patient Education  24 results see all →