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About 3,897 results

ALLMedicine™ Bacterial Pneumonia Center

Research & Reviews  1,641 results

Pharmacokinetics and Safety of Lefamulin After Single Intravenous Dose Administration i...
https://doi.org/10.1002/phar.2522
Pharmacotherapy Wicha WW, Marbury TC et. al.

Apr 3rd, 2021 - Lefamulin is a novel pleuromutilin recently approved by the FDA for the treatment of community-acquired bacterial pneumonia. Given that lefamulin is primarily metabolized by CYP450 Phase-1 reactions, this study evaluated the pharmacokinetics of IV...

Pharmacokinetics and Safety of Lefamulin After Single Intravenous Dose Administration i...
https://doi.org/10.1002/phar.2523
Pharmacotherapy Wicha WW, Marbury TC et. al.

Apr 2nd, 2021 - Lefamulin is a novel IV and oral pleuromutilin recently approved for the treatment of community-acquired bacterial pneumonia (CABP). Given that renal comorbidities are common in patients admitted for CABP, understanding the pharmacokinetics of lef...

A Phase 3, Randomized, Double-Blind Study Comparing Tedizolid Phosphate and Linezolid f...
https://doi.org/10.1093/cid/ciab032
Clinical Infectious Diseases : an Official Publication Of... Wunderink RG, Roquilly A et. al.

Mar 15th, 2021 - Hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) are associated with high mortality rates. We evaluated the efficacy and safety of tedizolid (administered as tedizolid phosphate) for treatment of gr...

Single-cell RNA sequencing reveals the sustained immune cell dysfunction in the pathoge...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937330
Genomics Wang T, Zhang X et. al.

Mar 10th, 2021 - Sepsis is a leading cause of mortality in intensive care unit worldwide, it's accompanied by immune cell dysfunction induced by multiple factors. However, little is known about the specific alterations in immune cells in the dynamic pathogenesis o...

Effect on 30-day mortality and duration of hospitalization of empirical antibiotic ther...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937361
Annals of Clinical Microbiology and Antimicrobials; Li R, Tang H et. al.

Mar 8th, 2021 - The objective of this study was to investigate whether unreasonable empirical antibiotic treatment (UEAT) had an impact on 30-day mortality and duration of hospitalization in bacterial pneumonia caused by carbapenem-resistant gram-negative bacteri...

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Guidelines  7 results

Shared Decision-Making for Administering PCV13 in Older Adults
https://www.aafp.org/afp/2020/0201/p134.html
American Family Physician; Shah AA,et al

Jan 31st, 2020 - Streptococcus pneumoniae infection, the most common cause of bacterial pneumonia, leads to significant morbidity and mortality in older people. With the addition of the pneumococcal conjugate vaccine to childhood immunization schedules in 2000, he...

Melinta Therapeutics Announces U.S. FDA Approval of Supplemental New Drug Application for BAXDELA® (delafloxacin) for the Treatment of Community-Acquired Bacterial Pneumonia (CABP)
http://ir.melinta.com/news-releases/news-release-details/melinta-therapeutics-announces-us-fda-approval-supplemental-new

Oct 23rd, 2019 - Melinta Therapeutics, Inc. (NASDAQ: MLNT), a commercial-stage company focused on the development and commercialization of novel antibiotics to treat serious bacterial infections, today announced the U.S. Food and Drug Administration (FDA) has appr...

Improving Conduct and Feasibility of Clinical Trials to Evaluate Antibacterial Drugs to...
https://doi.org/10.1093/cid/ciw258
Clinical Infectious Diseases : an Official Publication Of... Knirsch C, Alemayehu D et. al.

Aug 2nd, 2016 - The etiology of hospital-acquired or ventilator-associated bacterial pneumonia (HABP/VABP) is often multidrug-resistant infections. The evaluation of new antibacterial drugs for efficacy in this population is important, as many antibacterial drugs...

Streamlining Safety Data Collection in Hospital-Acquired Bacterial Pneumonia and Ventil...
https://doi.org/10.1093/cid/ciw316
Clinical Infectious Diseases : an Official Publication Of... Donnelly H, Alemayehu D et. al.

Aug 2nd, 2016 - Resistant bacteria are one of the leading causes of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP). HABP/VABP trials are complex and difficult to conduct due to the large number of medical procedures, adverse events, and c...

XENLETA™ (lefamulin) Website for Healthcare Professionals
https://www.xenleta.com/

community-acquired bacterial pneumonia See XENLETA™ (lefamulin) clinical trial results and product attributes

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Drugs  141 results see all →

Clinicaltrials.gov  1,911 results

Recarbrio - imipenem anhydrous, cilastatin, and relebactam anhydrous injection, powder, for solution-Merck Sharp & Dohme Corp.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=be32f468-738b-40df-a425-591e12f65159

Apr 8th, 2021 - RECARBRIO is a combination of imipenem, a penem antibacterial, cilastatin, a renal dehydropeptidase inhibitor, and relebactam, a beta-lactamase inhibitor, indicated in patients 18 years of age and older for the treatment of the following infection...

Pharmacokinetics and Safety of Lefamulin After Single Intravenous Dose Administration i...
https://doi.org/10.1002/phar.2522
Pharmacotherapy Wicha WW, Marbury TC et. al.

Apr 3rd, 2021 - Lefamulin is a novel pleuromutilin recently approved by the FDA for the treatment of community-acquired bacterial pneumonia. Given that lefamulin is primarily metabolized by CYP450 Phase-1 reactions, this study evaluated the pharmacokinetics of IV...

Pharmacokinetics and Safety of Lefamulin After Single Intravenous Dose Administration i...
https://doi.org/10.1002/phar.2523
Pharmacotherapy Wicha WW, Marbury TC et. al.

Apr 2nd, 2021 - Lefamulin is a novel IV and oral pleuromutilin recently approved for the treatment of community-acquired bacterial pneumonia (CABP). Given that renal comorbidities are common in patients admitted for CABP, understanding the pharmacokinetics of lef...

A Phase 3, Randomized, Double-Blind Study Comparing Tedizolid Phosphate and Linezolid f...
https://doi.org/10.1093/cid/ciab032
Clinical Infectious Diseases : an Official Publication Of... Wunderink RG, Roquilly A et. al.

Mar 15th, 2021 - Hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) are associated with high mortality rates. We evaluated the efficacy and safety of tedizolid (administered as tedizolid phosphate) for treatment of gr...

Online COVID-19 Symptom Checkers May Not Catch Severe Illnesses
https://www.medscape.com/viewarticle/947253

Mar 11th, 2021 - NEW YORK (Reuters Health) - Digital COVID-19 symptom checkers in the U.S. and the U.K. may fail to identify severe COVID-19 and other serious illnesses such as bacterial pneumonia or sepsis, according to a group of public-health researchers. The o...

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News  195 results

Online COVID-19 Symptom Checkers May Not Catch Severe Illnesses
https://www.medscape.com/viewarticle/947253

Mar 11th, 2021 - NEW YORK (Reuters Health) - Digital COVID-19 symptom checkers in the U.S. and the U.K. may fail to identify severe COVID-19 and other serious illnesses such as bacterial pneumonia or sepsis, according to a group of public-health researchers. The o...

How the COVID Pandemic May End: Lessons From the 1918 Flu
https://www.medscape.com/viewarticle/940788

Nov 11th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The Spanish flu hit in the fall of 1918; a second surge occurred from January to April 1919, and a smaller one followed in the winter of 1920. Forty million peop...

As COVID-19 Cases Spike, Pneumonia Vaccine Demand Rockets and Europe Runs Low
https://www.staging.medscape.com/viewarticle/939667

Oct 25th, 2020 - MILAN/FRANKFURT/NEW YORK (Reuters) - As COVID-19 infections rise, people seeking to avoid one lung disease compounding another are queuing up to get inoculated against bacterial pneumonia, causing shortages of a Merck & Co vaccine in parts of Euro...

Fast Five Quiz: Pneumonia Key Aspects
https://reference.medscape.com/viewarticle/922410_2

Mar 22nd, 2020 - Physical examination findings may vary depending on the type of organism, severity of infection, coexisting host factors, and presence of complications. Signs of bacterial pneumonia may include the following: Hyperthermia (fever, typically > 38°C)...

Fast Five Quiz: Pneumonia Key Aspects
https://reference.medscape.com/viewarticle/922410

Mar 22nd, 2020 - Bacterial pneumonia is caused by a pathogenic infection of the lungs and may present as a primary disease process or as the final, fatal disorder, primarily in an individual who is already debilitated. Community-acquired pneumonia (CAP) is one of ...

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Patient Education  2 results see all →