ALLMedicine™ Aspergillosis Center

May 18th, 2022 - Patients with chronic granulomatous disease, a primary immunodeficiency, experience granulomatous complications and recurrent life-threatening opportunistic bacterial and fungal infections. In this article, we report on a case of invasive aspergil...

May 17th, 2022 - Voriconazole is the first line treatment for invasive aspergillosis (IA) Current guidelines suggest performing regular voriconazole therapeutic drug monitoring (TDM) to optimize treatment efficacy. We aimed to determine if TDM was predictive of cl...

May 12th, 2022 - Bendamustine is a standard treatment for low-grade B-cell lymphomas, and considered safe in clinical trials. Its safety in routine practice might be different. We retrospectively analyzed the infection complications in an unselected cohort of pati...

May 11th, 2022 - Approach Considerations Laboratory assessments and studies are not routinely indicated for the diagnosis of asthma, but they may be used to exclude other diagnoses. Eosinophilia and elevated serum IgE levels may help guide therapy in some cases. A...

Apr 28th, 2022 - Primary ciliary dyskinesia (PCD) is a rare inherited disease that affects the movement of the respiratory cilia. The main clinical manifestations are chronic upper and lower respiratory symptoms and recurrent lung infections, particularly bacteria...

Aug 31st, 2019 - Background: Fungal infections are of increasing incidence and importance in immunocompromised and immunocompetent patients. Timely diagnosis relies on appropriate use of laboratory testing in susceptible patients.Methods: The relevant literature r...

Jun 4th, 2019 - Presenting symptoms, distributions and patterns of diseases and vulnerability to invasive aspergillosis (IA) are similar between children and adults. However, differences exist in the epidemiology and underlying conditions, the usefulness of newer...

Sep 8th, 2018 - Voriconazole (VRZ) is a second-generation triazole antifungal agent with broad-spectrum activity. It is available in both intravenous and oral formulations, and is primarily indicated for treating invasive aspergillosis. The most commonly used dos...

Mar 17th, 2018 - The European Society for Clinical Microbiology and Infectious Diseases, the European Confederation of Medical Mycology and the European Respiratory Society Joint Clinical Guidelines focus on diagnosis and management of aspergillosis. Of the numero...

Dec 25th, 2016 - The European Conference on Infections in Leukemia (ECIL) provides recommendations for diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various types of infection in patients with hematologic malignancies or he...

Apr 8th, 2022 - Treatment will begin on Day 1 and then participants will be followed for 60 days post-last dose for safety. Treatment will be administered until the participant has a successful outcome or for a maximum duration of 84 days (IA) or 180 days (IM), w...

Mar 23rd, 2022 - Invasive aspergillosis (IA) is the most common mould infection in immunocompromised haematological patients. A relatively low mortality is observed when diagnosis is made early and treatment with voriconazole, the first choice of treatment, is ini...

Jan 25th, 2022 - This trial is aimed to study the immunological and pathological characteristics of influenza versus non-influenza severe community-acquired pneumonia patients in ICU, and correlate findings with occurrence of secondary invasive pulmonary aspergill...

Dec 9th, 2021 - Invasive filamentous fungal infections (aspergillosis, scedosporiosis, mucormycosis, fusarium wilt) are frequent and serious in immunocompromised individuals and especially in organ transplant patients. There is little recent data in liver transpl...

Oct 12th, 2021 - Aspergillus is a saprophytic fungus which is present normally in our surroundings and causes a large number of pulmonary diseases spreading through inhalational route. The spectrum of disease caused by aspergillus spp. is wide with the manifestati...

Apr 22nd, 2022 - NEW YORK (Reuters Health) - A 12-month course of itraconazole was superior to a six-month course at reducing relapses of chronic pulmonary aspergillosis in a randomized controlled trial conducted in India. "Preventing relapses and thereby further ...

Aug 9th, 2021 - Fewer than half of liver transplant patients who developed invasive fungal infections (IFI) died after surgery, with several key factors contributing to mortality risk, researchers found in a small retrospective study. Out of 33 patients who devel...

Jul 22nd, 2021 - Bronchiectasis is a chronic condition characterised by symptoms of persistent or recurrent bronchial sepsis caused by irreversible damage to and dilation of the bronchi.[1] The key principles of the diagnosis and management of bronchiectasis were ...

Apr 28th, 2021 - Key clinical point : Invasive fungal infections, though rare, have been observed in multiple sclerosis patients using a range of disease-modifying treatments and should be suspected in patients presenting with signs of infection. Major finding : T.

Jan 27th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Hospitalist Sarah Stone, MD, arrived for her dayshift at Sharp Chula Vista in California one day in late December. The ICU and hospital wards were...