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About 308 results

ALLMedicine™ Alpha1-antitrypsin Deficiency Center

Research & Reviews  145 results

Comparison of different algorithms in laboratory diagnosis of Alpha1-antitrypsin defici...
https://doi.org/10.1515/cclm-2020-1881
Clinical Chemistry and Laboratory Medicine; Balderacchi AM, Barzon V et. al.

Mar 6th, 2021 - Alpha1-antitrypsin deficiency (AATD) is an inherited condition that predisposes individuals to an increased risk of developing lung and liver disease. Even though AATD is one of the most widespread inherited diseases in Caucasian populations, only...

Alpha1-antitrypsin deficiency and asthma.
https://doi.org/10.1097/ACI.0000000000000711
Current Opinion in Allergy and Clinical Immunology; Pini L, Paoletti G et. al.

Dec 7th, 2020 - The aim of the article is to highlight the association between α1-antitrypsin deficiency (AATD) and asthma. AATD is one of the most common and underrecognized autosomal disorders associated with an increased risk of developing liver and lung disea...

Pulmonary Manifestations of Gastrointestinal, Pancreatic, and Liver Diseases in Children.
https://doi.org/10.1016/j.pcl.2020.09.002
Pediatric Clinics of North America; Le Fevre ER, McGrath KH et. al.

Nov 24th, 2020 - Pulmonary manifestations of gastrointestinal (GI) diseases are often subtle, and underlying disease may precede overt symptoms. A high index of suspicion and a low threshold for consultation with a pediatric pulmonologist is warranted in common GI...

Endo-phenotyping of COPD patients.
https://doi.org/10.1080/17476348.2020.1804364
Expert Review of Respiratory Medicine; Barnes PJ

Jul 30th, 2020 - Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome and may comprise several different phenotypes that are driven by different molecular mechanisms (endotypes). Several different clinical, genetic, and inflammatory phenotypes ...

Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease.
https://doi.org/10.1016/j.cld.2020.04.010
Clinics in Liver Disease; Manne V, Kowdley KV

Jul 5th, 2020 - Alpha1-antitrypsin deficiency (A1ATD) is an inherited cause of chronic liver disease. It is inherited in an autosomal codominant pattern with each inherited allele expressed in the formation of the final protein, which is primarily produced in hep...

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Guidelines  1 results

GLASSIA [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
https://www.fda.gov/downloads/ApprovedProducts/UCM217890.pdf

GLASSIA is an alpha1-proteinase inhibitor that is indicated for chronic augmentation and maintenance therapy in adults with emphysema due to congenital deficiency of alpha1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin deficiency

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Drugs  4 results see all →

Clinicaltrials.gov  155 results

Comparison of different algorithms in laboratory diagnosis of Alpha1-antitrypsin defici...
https://doi.org/10.1515/cclm-2020-1881
Clinical Chemistry and Laboratory Medicine; Balderacchi AM, Barzon V et. al.

Mar 6th, 2021 - Alpha1-antitrypsin deficiency (AATD) is an inherited condition that predisposes individuals to an increased risk of developing lung and liver disease. Even though AATD is one of the most widespread inherited diseases in Caucasian populations, only...

Prolastin-c liquid - alpha1-proteinase inhibitor (human) injection, solution-GRIFOLS USA, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2b620e6b-6a24-0957-1288-ae529c4cc3a2

Dec 22nd, 2020 - PROLASTIN®-C LIQUID is an Alpha1-Proteinase Inhibitor (Human) (Alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of Alpha1-PI (alpha1-antitrypsin...

Alpha1-antitrypsin deficiency and asthma.
https://doi.org/10.1097/ACI.0000000000000711
Current Opinion in Allergy and Clinical Immunology; Pini L, Paoletti G et. al.

Dec 7th, 2020 - The aim of the article is to highlight the association between α1-antitrypsin deficiency (AATD) and asthma. AATD is one of the most common and underrecognized autosomal disorders associated with an increased risk of developing liver and lung disea...

Pulmonary Manifestations of Gastrointestinal, Pancreatic, and Liver Diseases in Children.
https://doi.org/10.1016/j.pcl.2020.09.002
Pediatric Clinics of North America; Le Fevre ER, McGrath KH et. al.

Nov 24th, 2020 - Pulmonary manifestations of gastrointestinal (GI) diseases are often subtle, and underlying disease may precede overt symptoms. A high index of suspicion and a low threshold for consultation with a pediatric pulmonologist is warranted in common GI...

Endo-phenotyping of COPD patients.
https://doi.org/10.1080/17476348.2020.1804364
Expert Review of Respiratory Medicine; Barnes PJ

Jul 30th, 2020 - Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome and may comprise several different phenotypes that are driven by different molecular mechanisms (endotypes). Several different clinical, genetic, and inflammatory phenotypes ...

see more →

News  3 results

Alpha1-Antitrypsin Deficiency Significantly Increases Risk for Lung Cancer
https://www.medscape.com/viewarticle/575125

May 26th, 2008 - May 27, 2008 — Alpha1-antitrypsin deficiency (AATD) can greatly increase the risk for lung cancer, researchers report. AATD carriers might have a risk of developing lung cancer that is 70% higher than that for noncarriers, according to new data pu...

Alpha1-Antitrypsin Deficiency Significantly Increases Risk for Lung Cancer
https://www.staging.medscape.com/viewarticle/575125

May 26th, 2008 - May 27, 2008 — Alpha1-antitrypsin deficiency (AATD) can greatly increase the risk for lung cancer, researchers report. AATD carriers might have a risk of developing lung cancer that is 70% higher than that for noncarriers, according to new data pu...

GLASSIA [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
https://www.fda.gov/downloads/ApprovedProducts/UCM217890.pdf

GLASSIA is an alpha1-proteinase inhibitor that is indicated for chronic augmentation and maintenance therapy in adults with emphysema due to congenital deficiency of alpha1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin deficiency

see more →