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About 446 results

ALLMedicine™ Leukocyte Adhesion Deficiency Center

Research & Reviews  223 results

Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency typ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805328
Blood Advances; Bakhtiar S, Salzmann-Manrique E et. al.

Feb 11th, 2021 - Type I and III leukocyte adhesion deficiencies (LADs) are primary immunodeficiency disorders resulting in early death due to infections and additional bleeding tendency in LAD-III. The curative treatment of LAD-I and LAD-III is allogeneic hematopo...

Incidental diagnosis of leukocyte adhesion deficiency type II following ABO typing.
https://doi.org/10.1016/j.clim.2020.108599
Clinical Immunology (Orlando, Fla.); Cooper N, Li YT et. al.

Sep 29th, 2020 - Individuals with the Bombay phenotype (Oh) in the ABO blood group system do not express the H, A, and B antigens but have no clinical symptoms. Bombay phenotype with clinical symptoms has been described in leukocyte adhesion deficiency type II (LA...

CIN or not: An approach to the evaluation and management of chronic idiopathic neutroph...
https://doi.org/10.1016/j.blre.2020.100739
Blood Reviews; Otieno SB, Altahan A et. al.

Aug 19th, 2020 - Neutrophilia refers to an increase in the number of circulating neutrophils in the peripheral blood. Some common etiologies include infection, inflammatory conditions, myeloproliferative disorders, malignancies, endocrinopathies, drugs, and anemia...

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808012
Blood Wen L, Marki A et. al.

Aug 10th, 2020 - Integrin-mediated neutrophil adhesion starts by arrest from rolling. Activation of integrins involves conformational changes from an inactive, bent conformation to an extended conformation (E+) with high affinity for ligand binding (H+). The cytop...

β2 Integrin Gene (ITGB2) mutation spectra in Pakistani families with leukocyte adhesion...
https://doi.org/10.1016/j.imbio.2020.151938
Immunobiology Nawaz Tipu H, Raza R et. al.

Apr 13th, 2020 - Leukocyte adhesion deficiency I (LADI) is an autosomal recessive type of primary immunodeficiency characterized by occurrence of repeated bacterial infections, impaired pus formation and wound healing. Genetic variations in the β-2 integrin subuni...

see more →

Clinicaltrials.gov  223 results

Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency typ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805328
Blood Advances; Bakhtiar S, Salzmann-Manrique E et. al.

Feb 11th, 2021 - Type I and III leukocyte adhesion deficiencies (LADs) are primary immunodeficiency disorders resulting in early death due to infections and additional bleeding tendency in LAD-III. The curative treatment of LAD-I and LAD-III is allogeneic hematopo...

Incidental diagnosis of leukocyte adhesion deficiency type II following ABO typing.
https://doi.org/10.1016/j.clim.2020.108599
Clinical Immunology (Orlando, Fla.); Cooper N, Li YT et. al.

Sep 29th, 2020 - Individuals with the Bombay phenotype (Oh) in the ABO blood group system do not express the H, A, and B antigens but have no clinical symptoms. Bombay phenotype with clinical symptoms has been described in leukocyte adhesion deficiency type II (LA...

CIN or not: An approach to the evaluation and management of chronic idiopathic neutroph...
https://doi.org/10.1016/j.blre.2020.100739
Blood Reviews; Otieno SB, Altahan A et. al.

Aug 19th, 2020 - Neutrophilia refers to an increase in the number of circulating neutrophils in the peripheral blood. Some common etiologies include infection, inflammatory conditions, myeloproliferative disorders, malignancies, endocrinopathies, drugs, and anemia...

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808012
Blood Wen L, Marki A et. al.

Aug 10th, 2020 - Integrin-mediated neutrophil adhesion starts by arrest from rolling. Activation of integrins involves conformational changes from an inactive, bent conformation to an extended conformation (E+) with high affinity for ligand binding (H+). The cytop...

β2 Integrin Gene (ITGB2) mutation spectra in Pakistani families with leukocyte adhesion...
https://doi.org/10.1016/j.imbio.2020.151938
Immunobiology Nawaz Tipu H, Raza R et. al.

Apr 13th, 2020 - Leukocyte adhesion deficiency I (LADI) is an autosomal recessive type of primary immunodeficiency characterized by occurrence of repeated bacterial infections, impaired pus formation and wound healing. Genetic variations in the β-2 integrin subuni...

see more →