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About 381 results

ALLMedicine™ Mevalonate Kinase Deficiency Center

Research & Reviews  185 results

Corrigendum to: Haploidentical α/β T-cell and B-cell depleted stem cell transplantation...
https://doi.org/10.1093/rheumatology/keab208
Rheumatology (Oxford, England); Faraci M, Giardino S et. al.

Mar 11th, 2021 - Corrigendum to: Haploidentical α/β T-cell and B-cell depleted stem cell transplantation in severe mevalonate kinase deficiency.|2021|Faraci M,Giardino S,Podestà M,Pierri F,Dell'Orso G,|

Gene Expression Analysis of Mevalonate Kinase Deficiency Affected Children Identifies M...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908123
International Journal of Environmental Research and Publi... Pisanti S, Citro M et. al.

Feb 2nd, 2021 - Mevalonate kinase deficiency (MKD) is a rare autoinflammatory genetic disorder characterized by recurrent fever attacks and systemic inflammation with potentially severe complications. Although it is recognized that the lack of protein prenylation...

HAPLOIDENTICAL α/β T-CELL AND B-CELL STEM CELL TRANSPLANTATION IN SEVERE MEVALONATE KIN...
https://doi.org/10.1093/rheumatology/keaa912
Rheumatology (Oxford, England); Faraci M, Giardino S et. al.

Jan 7th, 2021 - Mevalonic aciduria (MA) represents the most severe of mevalonate kinase deficiency (MKD). Patients with MA have an incomplete response even to high doses of anti-cytokine drugs as anakinra or canakinumab and stem cell transplantation (SCT) represe...

Burden of illness in hereditary periodic fevers: a multinational observational patient ...
https://www.ncbi.nlm.nih.gov/pubmed/33025894
Clinical and Experimental Rheumatology; Kuemmerle-Deschner JB, Quartier P et. al.

Oct 7th, 2020 - This study aimed to characterise the burden of illness of patients with inadequately controlled hereditary periodic fevers (HPFs), during and outside of flares. It was focused on the burden to the patients and also considered the wider impact on t...

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Guidelines  1 results

Consensus protocols for the diagnosis and management of the hereditary autoinflammatory...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027082
Pediatric Rheumatology Online Journal; Hansmann S, Lainka E et. al.

Feb 18th, 2020 - Rare autoinflammatory diseases (AIDs) including Cryopyrin-Associated Periodic Syndrome (CAPS), Tumor Necrosis Receptor-Associated Periodic Syndrome (TRAPS) and Mevalonate Kinase Deficiency Syndrome (MKD)/ Hyper-IgD Syndrome (HIDS) are genetically ...

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Drugs  2 results see all →

Clinicaltrials.gov  191 results

Corrigendum to: Haploidentical α/β T-cell and B-cell depleted stem cell transplantation...
https://doi.org/10.1093/rheumatology/keab208
Rheumatology (Oxford, England); Faraci M, Giardino S et. al.

Mar 11th, 2021 - Corrigendum to: Haploidentical α/β T-cell and B-cell depleted stem cell transplantation in severe mevalonate kinase deficiency.|2021|Faraci M,Giardino S,Podestà M,Pierri F,Dell'Orso G,|

Gene Expression Analysis of Mevalonate Kinase Deficiency Affected Children Identifies M...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908123
International Journal of Environmental Research and Publi... Pisanti S, Citro M et. al.

Feb 2nd, 2021 - Mevalonate kinase deficiency (MKD) is a rare autoinflammatory genetic disorder characterized by recurrent fever attacks and systemic inflammation with potentially severe complications. Although it is recognized that the lack of protein prenylation...

HAPLOIDENTICAL α/β T-CELL AND B-CELL STEM CELL TRANSPLANTATION IN SEVERE MEVALONATE KIN...
https://doi.org/10.1093/rheumatology/keaa912
Rheumatology (Oxford, England); Faraci M, Giardino S et. al.

Jan 7th, 2021 - Mevalonic aciduria (MA) represents the most severe of mevalonate kinase deficiency (MKD). Patients with MA have an incomplete response even to high doses of anti-cytokine drugs as anakinra or canakinumab and stem cell transplantation (SCT) represe...

Burden of illness in hereditary periodic fevers: a multinational observational patient ...
https://www.ncbi.nlm.nih.gov/pubmed/33025894
Clinical and Experimental Rheumatology; Kuemmerle-Deschner JB, Quartier P et. al.

Oct 7th, 2020 - This study aimed to characterise the burden of illness of patients with inadequately controlled hereditary periodic fevers (HPFs), during and outside of flares. It was focused on the burden to the patients and also considered the wider impact on t...

see more →

News  2 results

Canakinumab controls periodic fever syndromes in post-flare and maintenance dosing
https://www.mdedge.com/internalmedicine/article/118666/pain/canakinumab-controls-periodic-fever-syndromes-post-flare-and
Alice Goodman

Nov 22nd, 2016 - WASHINGTON – Prolonged dosing with canakinumab, an anti-interleukin-1beta monoclonal antibody, confirmed its efficacy in controlling flares in three rare autoinflammatory diseases grouped as periodic fever syndromes: familial Mediterranean fever,.

Canakinumab (Ilaris) Gets FDA Nod for Three Rare Periodic Fever Syndromes
https://www.medscape.com/viewarticle/869226

Sep 25th, 2016 - The US Food and Drug Administration (FDA) has approved three new indications for the interleukin-1-β inhibitor canakinumab (Ilaris, Novartis). They are tumor necrosis factor receptor–associated periodic syndrome (TRAPS), hyperimmunoglobulin D synd...

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