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About 1,723 results

ALLMedicine™ Autoimmune Hemolytic Anemia Center

Research & Reviews  592 results

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ANX005 in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA)
https://clinicaltrials.gov/ct2/show/NCT04691570

Jun 24th, 2022 - After being informed of study details and potential risks, all participants who provide written informed consent will undergo an up to 6-week screening period to determine eligibility. Participants who meet the eligibility criteria will receive tw...

The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT05004259

Jun 21st, 2022 - Autoimmune Hemolytic Anemia (AIHA) is a hematologic disorder in which the red blood cells are targeted and destroyed by autoantibodies produced by the immune system, specifically B-cells and plasma cells. It can be either idiopathic, or secondary ...

Autoimmune hemolytic anemia: causes and consequences.
https://doi.org/10.1080/1744666X.2022.2089115
Expert Review of Clinical Immunology; Fattizzo B, Barcellini W

Jun 16th, 2022 - Autoimmune hemolytic anemia (AIHA) is classified according to the direct antiglobulin test (DAT) and thermal characteristics of the autoantibody into warm and cold forms, and in primary versus secondary depending on the presence of associated cond...

Concurrent severe pulmonary tuberculosis with Evans syndrome: a case report with litera...
https://doi.org/10.1186/s12879-022-07512-1 10.1128/microbiolspec.TNMI7-0004-2016 10.1016/j.it.2016.09.007 10.5811/cpcem.2019.1.41028 10.1182/asheducation-2018.1.382 10.3390/jcm9123851 10.2147/JBM.S176144 10.3389/fpubh.2021.728768 10.1191/0961203306lu2262xx 10.3389/fimmu.2021.676132 10.1002/ccr3.4113
BMC Infectious Diseases; Pan XH, Xu JK et. al.

Jun 13th, 2022 - Tuberculosis is a bacterial infection involving multiple organs and systems. Its hematological presentation mainly includes anemia and leukocytosis. Evans syndrome is a rare autoimmune disease characterized by autoimmune hemolytic anemia, immune t...

Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT04119050

Jun 8th, 2022 - The study consists of a 24-week double-blind, placebo control period, a 144-week open-label extension period and follow-up period of 6 weeks after last assessment. Eligible participants will be randomized to placebo or nipocalimab (2 dose levels) ...

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Clinicaltrials.gov  52 results

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ANX005 in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA)
https://clinicaltrials.gov/ct2/show/NCT04691570

Jun 24th, 2022 - After being informed of study details and potential risks, all participants who provide written informed consent will undergo an up to 6-week screening period to determine eligibility. Participants who meet the eligibility criteria will receive tw...

The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT05004259

Jun 21st, 2022 - Autoimmune Hemolytic Anemia (AIHA) is a hematologic disorder in which the red blood cells are targeted and destroyed by autoantibodies produced by the immune system, specifically B-cells and plasma cells. It can be either idiopathic, or secondary ...

Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT04119050

Jun 8th, 2022 - The study consists of a 24-week double-blind, placebo control period, a 144-week open-label extension period and follow-up period of 6 weeks after last assessment. Eligible participants will be randomized to placebo or nipocalimab (2 dose levels) ...

A Study of INCB050465 in Participants With Autoimmune Hemolytic Anemia
https://clinicaltrials.gov/ct2/show/NCT03538041

May 18th, 2022 - The purpose of this study is to evaluate the safety and efficacy of parsaclisib administered orally to participants with autoimmune hemolytic anemia (AIHA) who have decreased hemoglobin and evidence of ongoing hemolysis that requires treatment int...

Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)
https://clinicaltrials.gov/ct2/show/NCT05002777

May 9th, 2022 - This is a single group treatment, Phase 2, open-label, study to evaluate the efficacy, safety and pharmacokinetics of rilzabrutinib in adult patients with wAIHA. All participants will receive rilzabrutinib orally. The screening period is up to 28 ...

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News  45 results

FDA Approves First Drug for Cold Agglutinin Disease
https://www.medscape.com/viewarticle/967966

Feb 7th, 2022 - A new drug has become the first and only treatment for people with cold agglutinin disease (CAD) that is approved by the US Food and Drug Administration (FDA). CAD is a rare autoimmune hemolytic anemia, affecting about 5000 people in the United St...

Fast Five Quiz: Cold Agglutinin Disease
https://www.medscape.com/viewarticle/959368

Nov 18th, 2021 - Cold agglutinin disease (CAD) is a rare, complement-dependent, classical pathway–mediated immune hemolytic disease, accounting for up to 25% of autoimmune hemolytic anemia. Whereas the incidence of CAD is rare, the disease burden is frequently hig...

Evans’ Syndrome in Undiagnosed Small Lymphocytic Lymphoma: Case Report and Literature Review
https://www.mdedge.com/fedprac/avaho/article/245949/lymphoma-plasma-cell-disorders/evans-syndrome-undiagnosed-small
Faith Opeyemi Abodunrin (faithabodunrin@creighton.edu), Abubakar Tauseef

Sep 10th, 2021 - Background Evans’ syndrome is a rare entity characterized by concomitant or sequential multilineage cytopenia particularly autoimmune hemolytic anemia, ITP and very rarely autoimmune neutropenia. Although more common in young adults, it can occur.

Challenges of Accurate Diagnosis of TA-TMA After Hematopoietic Stem Cell Transplant
https://www.onclive.com/view/challenges-of-accurate-diagnosis-of-ta-tma-after-hematopoietic-stem-cell-transplant

Apr 8th, 2021 - Samer Khaled, MD: That is a good segue to our next segment about the challenges of a prompt and accurate diagnosis of TA-TMA [transplant-associated thrombotic microangiopathy]. One of the challenges is to identify TA-TMA early in the course of the...

An International Experience at Home
https://www.onclive.com/view/an-international-experience-at-home

Dec 5th, 2020 - Christopher Dittus, DO, MPH I often find myself in awe of physicians who travel around the world seeking out the 2 most desirable aspects of medicine—patients in desperate need of medical care and patients with genuinely novel pathology. The dow...

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