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About 123,638 results

ALLMedicine™ Tuberculosis Center

Research & Reviews  60,029 results

Clozapine-Associated Leukopenia and Agranulocytosis in Western Cape, South Africa: A 3-...
https://doi.org/10.1097/JCP.0000000000001394
Journal of Clinical Psychopharmacology; Geldenhuys C, Zunza M et. al.

Apr 12th, 2021 - Clozapine may cause life-threatening hematological side effects (HSEs). Hematological side effect incidence data from Sub-Saharan Africa are lacking. Furthermore, clozapine reduces cellular immunity, and it is unknown whether clozapine is a risk f...

MPT64 assays for the rapid detection of Mycobacterium tuberculosis.
https://doi.org/10.1186/s12879-021-06022-w 10.1016/j.bios.2018.05.017 10.1159/000273073 10.1097/MD.0000000000018073 10.1016/j.ijtb.2015.04.007 10.1016/j.ijid.2020.04.059 10.7883/yoken.JJID.2018.128 10.5588/ijtld.11.0356 10.7326/0003-4819-155-8-201110180-00009 10.2214/AJR.17.18774 10.1016/S0895-4356(03)00177-X 10.1186/s12879-020-4852-z 10.1186/s12865-019-0315-y 10.5588/ijtld.18.0060 10.1099/jmm.0.000846 10.1099/jmm.0.000726 10.1155/2017/3259329 10.4103/IJPM.IJPM_695_15 10.4102/ajlm.v6i2.383 10.4103/0377-4929.182009 10.3349/ymj.2014.55.3.746 10.1186/1471-2334-13-430 10.1097/PAT.0b013e328359d565 10.1016/j.diagmicrobio.2012.08.007 10.5588/ijtld.10.0474 10.1016/j.diagmicrobio.2010.11.009 10.5588/ijtld.10.0709 10.1128/JCM.02243-10 10.1186/1746-1596-2-36 10.1038/modpathol.3800697 10.1128/JCM.42.1.390-392.2004 10.1128/JCM.40.3.908-912.2002 10.1128/JCM.37.11.3693-3697.1999 10.17305/bjbms.2012.2531 10.5897/AJMR-11-1481 10.1128/JCM.05995-11 10.1016/j.diagmicrobio.2010.12.011 10.1128/JCM.00571-11 10.1128/JCM.01906-10 10.1590/S0074-02762011000600022 10.1128/JCM.01688-09 10.1016/j.diagmicrobio.2007.06.010 10.1111/j.1365-3156.2009.02284.x
BMC Infectious Diseases; Cao XJ, Li YP et. al.

Apr 11th, 2021 - Tuberculosis (TB) is a serious infectious disease caused by Mycobacterium tuberculosis (MTB). An estimated 1.7 billion people worldwide are infected with Mycobacterium tuberculosis (LTBI) during the incubation period without any obvious symptoms. ...

Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma...
https://doi.org/10.1016/j.ejps.2021.105831
European Journal of Pharmaceutical Sciences : Official Jo... Valente E, Testa B et. al.

Apr 11th, 2021 - Due to difficulties in drug penetration in M. tuberculosis, a prodrug approach based on mycobacterial activation appears as a promising strategy to increase the delivery of antitubercular drugs to the target microorganisms. Esters have been succes...

The escalating tuberculosis crisis in central and South American prisons.
https://doi.org/10.1016/S0140-6736(20)32578-2
Lancet (London, England); Walter KS, Martinez L et. al.

Apr 11th, 2021 - In the past decade, tuberculosis incidence has declined in much of the world, but has risen in central and South America. It is not yet clear what is driving this reversal of progress in tuberculosis control. Since 2000, the incarcerated populatio...

Outcomes of multidrug-resistant tuberculosis treated with bedaquiline or delamanid.
https://doi.org/10.1093/cid/ciab304
Clinical Infectious Diseases : an Official Publication Of... Hwang H, Kang H et. al.

Apr 10th, 2021 - Since September 1, 2016, bedaquiline and delamanid have been administered for treatment of patients with multidrug-resistant/rifampicin-resistant tuberculosis after the official approval in South Korea. This study aimed to assess and compare the f...

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Guidelines  127 results

Tuberculosis — United States, 2020
https://www.cdc.gov/mmwr/volumes/70/wr/mm7012a1.htm
MMWR Morb Mortal Wkly; Deutsch-Feldman M, Pratt RH et. al.

Mar 25th, 2021 - Tuberculosis (TB) disease incidence has decreased steadily since 1993 (1), a result of decades of work by local TB programs to detect, treat, and prevent TB disease and transmission. During 2020, a total of 7,163 TB cases were provisionally report...

Improving Quality of Patient Data for Treatment of Multidrug- or Rifampin-Resistant Tub...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045826
Emerging Infectious Diseases; Campbell JR, Falzon D et. al.

Jan 10th, 2020 - International policy for treatment of multidrug- and rifampin-resistant tuberculosis (MDR/RR TB) relies largely on individual patient data (IPD) from observational studies of patients treated under routine conditions. We prepared guidance on which...

Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline
https://www.atsjournals.org/doi/full/10.1164/rccm.201909-1874ST
American Journal of Respiratory and Critical Care Medicine; Payam Nahid et al

Nov 20th, 2019 - The American Thoracic Society, U.S. Centers for Disease Control and Prevention, European Respiratory Society, and Infectious Diseases Society of America jointly sponsored this new practice guideline on the treatment of drug-resistant tuberculosis ...

Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857485
American Journal of Respiratory and Critical Care Medicine; Nahid P, Mase SR et. al.

Nov 15th, 2019 - Background: The American Thoracic Society, U.S. Centers for Disease Control and Prevention, European Respiratory Society, and Infectious Diseases Society of America jointly sponsored this new practice guideline on the treatment of drug-resistant t...

Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis
https://www.nejm.org/doi/full/10.1056/NEJMoa1909953
The New England Journal of Medicine; Tait,D.,et al

Oct 28th, 2019 - BACKGROUND Results of an earlier analysis of a trial of the M72/AS01E candidate vaccine against Mycobacterium tuberculosis showed that in infected adults, the vaccine provided 54.0% protection against active pulmonary tuberculosis disease, without...

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Drugs  249 results see all →

Clinicaltrials.gov  61,589 results

Clozapine-Associated Leukopenia and Agranulocytosis in Western Cape, South Africa: A 3-...
https://doi.org/10.1097/JCP.0000000000001394
Journal of Clinical Psychopharmacology; Geldenhuys C, Zunza M et. al.

Apr 12th, 2021 - Clozapine may cause life-threatening hematological side effects (HSEs). Hematological side effect incidence data from Sub-Saharan Africa are lacking. Furthermore, clozapine reduces cellular immunity, and it is unknown whether clozapine is a risk f...

MPT64 assays for the rapid detection of Mycobacterium tuberculosis.
https://doi.org/10.1186/s12879-021-06022-w 10.1016/j.bios.2018.05.017 10.1159/000273073 10.1097/MD.0000000000018073 10.1016/j.ijtb.2015.04.007 10.1016/j.ijid.2020.04.059 10.7883/yoken.JJID.2018.128 10.5588/ijtld.11.0356 10.7326/0003-4819-155-8-201110180-00009 10.2214/AJR.17.18774 10.1016/S0895-4356(03)00177-X 10.1186/s12879-020-4852-z 10.1186/s12865-019-0315-y 10.5588/ijtld.18.0060 10.1099/jmm.0.000846 10.1099/jmm.0.000726 10.1155/2017/3259329 10.4103/IJPM.IJPM_695_15 10.4102/ajlm.v6i2.383 10.4103/0377-4929.182009 10.3349/ymj.2014.55.3.746 10.1186/1471-2334-13-430 10.1097/PAT.0b013e328359d565 10.1016/j.diagmicrobio.2012.08.007 10.5588/ijtld.10.0474 10.1016/j.diagmicrobio.2010.11.009 10.5588/ijtld.10.0709 10.1128/JCM.02243-10 10.1186/1746-1596-2-36 10.1038/modpathol.3800697 10.1128/JCM.42.1.390-392.2004 10.1128/JCM.40.3.908-912.2002 10.1128/JCM.37.11.3693-3697.1999 10.17305/bjbms.2012.2531 10.5897/AJMR-11-1481 10.1128/JCM.05995-11 10.1016/j.diagmicrobio.2010.12.011 10.1128/JCM.00571-11 10.1128/JCM.01906-10 10.1590/S0074-02762011000600022 10.1128/JCM.01688-09 10.1016/j.diagmicrobio.2007.06.010 10.1111/j.1365-3156.2009.02284.x
BMC Infectious Diseases; Cao XJ, Li YP et. al.

Apr 11th, 2021 - Tuberculosis (TB) is a serious infectious disease caused by Mycobacterium tuberculosis (MTB). An estimated 1.7 billion people worldwide are infected with Mycobacterium tuberculosis (LTBI) during the incubation period without any obvious symptoms. ...

Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma...
https://doi.org/10.1016/j.ejps.2021.105831
European Journal of Pharmaceutical Sciences : Official Jo... Valente E, Testa B et. al.

Apr 11th, 2021 - Due to difficulties in drug penetration in M. tuberculosis, a prodrug approach based on mycobacterial activation appears as a promising strategy to increase the delivery of antitubercular drugs to the target microorganisms. Esters have been succes...

The escalating tuberculosis crisis in central and South American prisons.
https://doi.org/10.1016/S0140-6736(20)32578-2
Lancet (London, England); Walter KS, Martinez L et. al.

Apr 11th, 2021 - In the past decade, tuberculosis incidence has declined in much of the world, but has risen in central and South America. It is not yet clear what is driving this reversal of progress in tuberculosis control. Since 2000, the incarcerated populatio...

Outcomes of multidrug-resistant tuberculosis treated with bedaquiline or delamanid.
https://doi.org/10.1093/cid/ciab304
Clinical Infectious Diseases : an Official Publication Of... Hwang H, Kang H et. al.

Apr 10th, 2021 - Since September 1, 2016, bedaquiline and delamanid have been administered for treatment of patients with multidrug-resistant/rifampicin-resistant tuberculosis after the official approval in South Korea. This study aimed to assess and compare the f...

see more →

News  1,621 results

South Africa Launches TB Mobile Clinics Amid COVID-19 Disruption
https://www.medscape.com/viewarticle/948203

Mar 28th, 2021 - CAPE TOWN (Reuters) - Parked on the roadside next to a graveyard in Cape Town's Gugulethu township, a tuberculosis hotspot, a team of health workers set up a makeshift TB screening room next to their van. Gladys Rara, 45, provides a sputum sample ...

Tuberculosis — United States, 2020
https://www.cdc.gov/mmwr/volumes/70/wr/mm7012a1.htm
MMWR Morb Mortal Wkly; Deutsch-Feldman M, Pratt RH et. al.

Mar 25th, 2021 - Tuberculosis (TB) disease incidence has decreased steadily since 1993 (1), a result of decades of work by local TB programs to detect, treat, and prevent TB disease and transmission. During 2020, a total of 7,163 TB cases were provisionally report...

Pediatric TB – More Work Needed, Especially With HIV Coinfection
https://www.medscape.com/viewarticle/947195

Mar 9th, 2021 - Despite recent advances in the diagnosis, treatment, and prevention of pediatric tuberculosis in children living with HIV (CLHIV) and HIV-exposed uninfected children (HEU), several unmet needs remain, including studies evaluating the feasibility o...

Are Long-Acting Injectables the Future of TB Treatment?
https://www.medscape.com/viewarticle/947201

Mar 9th, 2021 - Long-acting injectable (LAI) drug formulations represent a promising new strategy for the prevention and treatment of tuberculosis in women and children, according to an online presentation at the Conference on Retroviruses & Opportunistic Infecti...

As Peru Battles COVID-19, Tuberculosis Finds New Footing
https://www.medscape.com/viewarticle/947111

Mar 8th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. In late February 2020, Martin Valencia Garcia was working as a community agent in Independencia, one of the denser districts of Lima, Peru. His jo...

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Patient Education  23 results see all →