ALLMedicine™ Cholera Center

May 15th, 2022 - Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action of antibiotics used against them. AR is rising to a high level across the globe, and novel resistant strains are emerging and spreading very fast. Acin...

May 15th, 2022 - Fecal contamination of water sources and open defecation have been linked to cholera outbreaks in India. However, a systematic review on the drivers responsible for these outbreaks has yet to be published. Here, we systematically review the publis...

May 15th, 2022 - In 2010, Haiti experienced one of the deadliest cholera outbreaks of the 21st century. United Nations (UN) peacekeepers are widely believed to have introduced cholera, and the UN has formally apologized to Haitians and accepted responsibility. The...

May 14th, 2022 - Mucosal-associated invariant T (MAIT) cells are unconventional T lymphocytes with a semi-conserved TCRα, activated by the presentation of vitamin B metabolites by the MHC-I related protein, MR1, and with diverse innate and adaptive effector functi...

May 10th, 2022 - Cholera causes substantial morbidity and mortality in the world's poorest populations. For nearly a decade, an inactivated oral cholera vaccine (OCV) stockpile has been available to control and prevent outbreaks. In 2017, WHO launched a bold globa...

May 12th, 2017 - Cholera, caused by infection with toxigenic Vibrio cholerae bacteria of serogroup O1 (>99% of global cases) or O139, is characterized by watery diarrhea that can be severe and rapidly fatal without prompt rehydration. Cholera is endemic in approxi...

Mar 23rd, 2022 - The World Health Organization (WHO) defines antimicrobial resistance (AMR) as a situation where drugs used to treat microbial infection caused by bacteria, viruses, fungi and parasites no longer work to treat infection because of the changes in th...

Mar 16th, 2022 - Aim 1. Develop an evidence and theory based WASH mHealth intervention for households in areas with confirmed cholera patients in Dhaka, Bangladesh through formative research Conduct formative research through in-depth interviews, focus group discu...

Mar 11th, 2022 - This study develops and evaluates a targeted water, sanitation, and hygiene (WASH) intervention to reduce cholera and severe diarrhea among the household members of diarrhea patients in South Kivu, Democratic Republic of the Congo (DRC) through fo...

Feb 10th, 2022 - The findings from the recent randomized controlled trial of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera infections in intervention hous...

Dec 16th, 2021 - The investigators plan to study immune non-inferiority, safety and lot-to-lot consistency of OCV-S compared to Shanchol™ in 1 to 40 years old healthy Nepalese participants. The investigators hypothesize that the simplified formulation is able to i...

Mar 10th, 2022 - Hypothermia, frostbite, respiratory diseases, mental health issues, and a lack of treatment for heart disease and cancer are the biggest health concerns at the moment for the people of Ukraine, the World Health Organization says. The WHO also is m...

Feb 23rd, 2022 - A new film called Salt in My Soul was recently released, with one of the expressed goals being to raise funds for phage research and antibiotic resistance. Mallory Smith The film shares the story of Mallory Smith, a young woman, now deceased, who ...

Sep 9th, 2021 - KINSHASA (Reuters) - A meningitis outbreak in Democratic Republic of Congo's north-eastern Tshopo province has killed 129 of the 267 people who have been infected since the first cases were discovered in June, the health minister said late on Tues...

Aug 20th, 2021 - Infectious Disease Tembexa (brincidofovir) Brincidofovir is a prodrug of cidofovir. Brincidofovir effectively penetrates cells via its lipid conjugate, releasing the nucleotide analog cidofovir, which then acts to inhibit viral replication. Cidofo...

Jul 9th, 2021 - NEW YORK (Reuters Health) - MucoRice-CTB, a cholera toxin B subunit (CTB) vaccine made by grinding up genetically modified grains of rice, showed promise in a proof-of-concept study, researchers say. "Although we have been developing the MucoRice-...